Jump to content
Celiac Disease FAQ | This site uses cookies GDPR notice. Read more... ×
  • Sign Up
0
mainemommy1

Enterolab Results-seems Mild -do I Still Avoid

Rate this topic

Recommended Posts

I did the Enterolab because my son's results came back positive including for the genes and I knew I had at least one of the genes going into the test. My numbers were not that much higher than the normal range but according to Enterolab's site, the actual number doesn't tell how severe other than you are having an immune reaction and shouldn't eat gluten-not even small amounts even though the numbers are not that high. My son's numbers were obviously out of range and very high . I know I am not celiac but I am guessing this means gluten sensitivity and I should avoid all gluten? symptoms include: hungry all the time, occasional digestion issues, very very tired, very low ferritin and vit d, headaches, trouble loosing weight -

Fecal Anti-gliadin IgA: 14 Units

Fecal Anti-tissue Transglutaminase IgA: 11 Units

Quantitative Microscopic Fecal Fat Score: Less than 300 Units

Fecal Anti-casein (cow's milk) IgA: 8 Units

HLA-DQB1 Molecular analysis, Allele 1: 0302

HLA-DQB1 Molecular analysis, Allele 2: 0202

Serologic equivalent: HLA-DQ 3,2 (Subtype 8,2)

Interpretation of Fecal Anti-gliadin IgA (Normal Range is less than 10 Units): Intestinal antigliadin IgA antibody was elevated, indicating that you have active dietary gluten sensitivity. For optimal health, resolution of symptoms (if you have them), and prevention of small intestinal damage and malnutrition, osteoporosis, and damage to other tissues (like nerves, brain, joints, muscles, thyroid, pancreas, other glands, skin, liver, spleen, among others), it is recommended that you follow a strict and permanent gluten free diet. As gluten sensitivity is a genetic syndrome, you may want to have your relatives screened as well.

Interpretation of Fecal Anti-tissue Transglutaminase IgA (Normal Range is less than 10 Units): You have an autoimmune reaction to the human enzyme tissue transglutaminase, secondary to dietary gluten sensitivity.

Interpretation of Quantitative Microscopic Fecal Fat Score (Normal Range is less than 300 Units): Provided that dietary fat is being ingested, a fecal fat score less than 300 indicates there is no malabsorbed dietary fat in stool indicating that digestion and absorption of nutrients is currently normal.

Interpretation of Fecal Anti-casein (cow's milk) IgA (Normal Range is less than 10 Units): Levels of fecal IgA antibody to a food antigen greater than or equal to 10 are indicative of an immune reaction, and hence immunologic "sensitivity" to that food. For any elevated fecal antibody level, it is recommended to remove that food from your diet. Values less than 10 indicate there currently is minimal or no reaction to that food and hence, no direct evidence of food sensitivity to that specific food. However, because 1 in 500 people cannot make IgA at all, and rarely, some people can still have clinically significant reactions to a food antigen despite the lack of a significant antibody reaction (because the reactions primarily involve T cells), if you have an immune syndrome or symptoms associated with food sensitivity, it is recommended that you try a strict removal of suspect foods from your diet for up to 12 months despite a negative test.

Interpretation Of HLA-DQ Testing: HLA-DQB1 gene analysis reveals that you have one of the main genes that predisposes to gluten sensitivity and celiac sprue (HLA-DQB1*0201 or HLA-DQB1*0302). Each of your offspring has a 50% chance of receiving this gene from you, and at least one of your parents passed it to you. You also have a second gene that by itself can rarely be associated with celiac sprue (HLA-DQ2 other than by HLA-DQB1*0201), and when associated with one of the main celiac genes, strengthens the predisposition to getting the disease, and with more severe manifestations. Having one celiac gene and one gluten sensitive gene, means that each of your parents, and all of your children (if you have them) will possess at least one copy of a gluten sensitive gene. Having two copies also means there is an even stronger predisposition to gluten sensitivity than having one gene and the resultant immunologic gluten sensitivity or celiac sprue may be more severe.

Share this post


Link to post
Share on other sites

Both you and your son have a gluten sensitivity according to Enterolabs interpretation. The genes indicate that you MAY be at risk or predisposed to several autoimmune disorders, but not specifically to Celiac according to what I understand.

May people choose Enterolab as a piece of a puzzle to include serologic blood panel, endoscopy/biopsy exams and dietary results. Collective results, in some combination, can be diagnostic of Celiac Disease.

To answer your question, you should remain on a full gluten diet until you have exausted your testing options in order to achieve a diagnosis, if that is your direction.

If not, try the diet and see if your symtoms improve.

Here is a good article on genetic testing:

http://www.celiac.com/articles/21567/1/Ten...ting/Page1.html

Bonfils, Quest and Enterolab only test for the beta subunit portions and therefore their test can miss part of a minor alpha subunit that carries a risk of Celiac disease. A negative DQ2 and DQ8 report from these labs may not necessarily be truly negative for the risk of Celiac disease.

Share this post


Link to post
Share on other sites

My Enterolab results were much like yours - only slightly elevated above the normal range.

I asked Enterolab about this because I was concerned, and they told me you have to look at it as if it were a pregnancy test - you can't be a little bit pregnant, you either are or you aren't. So a positive result of any kind is still positive, no matter what the numbers are. All of our bodies are different from one another's so it's no wonder we all have different results.

You've already received great advice from Momma Goose. If you're still skeptical and if you want further testing you should definitely pursue it before starting the diet.

Let us know how everything goes. Good luck :)

Share this post


Link to post
Share on other sites

Thanks everyone! I was wondering if everyone had mildly elevated test results and if they experienced success with the diet. Honestly, I am not interested in additional testing-I'll just follow the diet. I wanted to know more for any future children I may have and for when I breastfeed them in terms of genes. My son was a miserable baby-labeled colic- but at one year of age I put my foot down-colic does not last for a year. I was up every hour, all night, every night for a year with him-not normal but no one was concerned but me. The nutritionist/natural dr suggested a gluten free diet and I had a different child. So, I have my issues with mainstream drs as it is. We recently started giving him gluten in the past year and noticed changes but just could not link it to when he ate the gluten. We did the test mainly because he'll be going to preschool and we wanted concrete evidence that he really did need to be gluten free. The nutritionist is writing me a letter for his school file and that will be that. I don't see any need to make either of us undergo invasive testing -I don't love gluten that much! I was just confused by my results being just over the cut off. Honestly, it will be much easier and probably healthier to just go all gluten free for the family and possibly avoid the traumatic first year my son had if we have any additional children. Thanks so much for your responses and taking the time to reply. What a nice group of people to have stumbled across online. Thank you everyone!

Share this post


Link to post
Share on other sites

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now
0

  • Top Posters +

  • Upcoming Events

    • February 27, 2019 04:00 PM Until 08:00 AM
      0  
       
       
       
      Celiac Emotional Healing Support Group
       
       
       
      Again you are invited to join Johnny Patout, LCSW for Baton Rouge's first emotional healing support group meeting to assist those living with celiac disease manage the emotional challenges so many of us face. Most often the emotional disturbances include depression, disinterest in normal activities, insomnia, grief, mood changes, anxiety, inability to concentrate, extreme concern about managing a gluten-free lifestyle and other emotional and behavioral challenges.
       
      The professionals at Jamestown Avenue Counseling Center created the emotional healing support group to give us a safe place to begin to process our emotions and support each other as we heal emotionally while managing celiac disease and the resulting autoimmune disorders.
       
      The emotional healing support group meets every Thursday, 6:00-7:00pm, at the Jamestown Avenue Counseling Center of Baton Rouge. Jamestown Avenue Counseling Center is located at 4637 Jamestown Avenue, Baton Rouge, Suite B-1. Suite B-1 is upstairs.
       
      The support group is free and open everyone managing celiac disease. For more information: emotionalhealingforceliacs@hotmail.com
    • March 24, 2019 Until March 27, 2019
      0  
      NEW ORLEANS GOURMET GLUTEN-FREE mini GETAWAY    March 24 ~ 27, 2019   We have arranged a fun and Gluten-free food filled mini in the city known for it's food and fun.  We have arranged to eat many of the famous dishes that aren't usually Gluten-free at a few of the World Renown restaurants.   Staying at the Royal Sonesta Hotel on Bourbon Street in the center of the French Quarter, you'll be able to enjoy the ambiance of the city at all hours.   Our itinerary will include a Luxury Coach tour of the city and surrounding area - Admission to The National World War II Museum, including the Tom Hanks" 4D film "Beyond All Boundaries" - an exciting Airboat ride and tour through the Bayou.      This it the 3rd time we have visited New Orleans and it has always been well attended, so join us even if you've been there before.  Check out our website for the complete itinerary and cost.    Due to contractual obligations we must have 20 participants by October 31, 2018 to make this a go.      If you have any questions just give us a call at 410-939-3218.  Bob & Ruth info@bobandruths.com (410) 939-3218
    • March 30, 2019 Until March 31, 2019
      0  
      Nourished Festival is a family-friendly event with 10 locations across the US. Attendees will be able to sample food, health and beauty products, meet with companies, learn about the most current food lifestyles, receive coupons and attend educational sessions with industry experts. 
      Nourished Festival, managed by The Nourished Group and presented by Enjoy Life Foods, is the largest gluten-free, allergy-friendly and specialty diet event in the US, with 10 locations including.
      ABOUT THE NOURISHED FESTIVALS
      Managed by The Nourished Group, formerly The Gluten Free Media Group, The Nourished Festivals are the largest and fastest growing special diet consumer events in the United States. Started in 2007, the events have expanded from one to ten cities throughout the country. The festivals cater to anyone looking to lead a healthier lifestyle or those who follow a specialty diet due to autoimmune conditions, food sensitivities, allergies or intolerances. Offerings including Paleo, Keto, Plant-Based, Gluten-Free, Allergen-Friendly and Nut-Free products. The events provide the opportunity for attendees to sample and purchase new products, receive coupons, meet with brand ambassadors and attend educational classes with industry experts. For more information, visit http://www.nourishedfestival.com 
       
×