Jump to content
  • Sign Up
  • Join Our Community!

    Do you have questions about celiac disease or the gluten-free diet?


Blood Test Negative, But I'm Immunoglobulin A Deficient

Rate this topic

Recommended Posts

Just a short background…

I’ve been experiencing some symptoms of Celiac for quite some time. I get extreme fatigue after I eat, have eczema, frequent and foul smelling gas, panic attacks, vertigo, bloating, and a history of Celiac in my family (both on my mom’s and dad’s sides). My blood test was negative but revealed that I am Immunoglobulin A deficient (<3, 61). I heard that when you are Immunoglobulin A deficient you are 10-15 times more likely to have a false negative. I’ve gone gluten free before and felt significantly different, but am unsure if that was from the gluten or just the diet change. I’m frustrated, and don’t know what to do as my next step. Has anyone had this happen to them, especially with Immunoglobulin A deficiency? Does anyone recommend a next step? I hear that a biopsy is better than blood work. Is this a sure-fire method of detection? Sorry for the long post. A lot is going through my head and it seems like every time I get results back they are inconclusive.

Thanks for the help.

Share this post

Link to post
Share on other sites

Yes I have. So have many others. The biopsy is not a for sure thing either unfortunately. You can either pursue a biopsy, you could go with Enterolab, they do not diagnose celiac but can tell you if you are forming antibodies to gluten or you could just go back on the diet strictly. If the diet helps IMHO that is the best test there is.

Share this post

Link to post
Share on other sites

If you are still eating gluten then I would do a combination of things. I would do IgG testing if that has not been already done and a biopsy. If those are inconclusive and you still do not feel like you have your answer, then you might consider genetic tests for celiac. ~97% of celiac patients are either HLA-DQ 02 and/or 0302 (08) positive.

Share this post

Link to post
Share on other sites

If they do a full panel, being IgA deficient shouldn't stop a diagnosis. But they have to run the IgG antibodies as well. If they didn't... well, they didn't test you very well at all. You might try asking for the IgG antibody tests.

Share this post

Link to post
Share on other sites

Join the conversation

You can post now and register later. If you have an account, sign in now to post with your account.
Note: Your post will require moderator approval before it will be visible.

Reply to this topic...

×   Pasted as rich text.   Paste as plain text instead

  Only 75 emoji are allowed.

×   Your link has been automatically embedded.   Display as a link instead

×   Your previous content has been restored.   Clear editor

×   You cannot paste images directly. Upload or insert images from URL.

  • Top Posters +

  • Upcoming Events

    • March 20, 2019 04:00 PM Until 08:00 AM
      Celiac Emotional Healing Support Group
      Again you are invited to join Johnny Patout, LCSW for Baton Rouge's first emotional healing support group meeting to assist those living with celiac disease manage the emotional challenges so many of us face. Most often the emotional disturbances include depression, disinterest in normal activities, insomnia, grief, mood changes, anxiety, inability to concentrate, extreme concern about managing a gluten-free lifestyle and other emotional and behavioral challenges.
      The professionals at Jamestown Avenue Counseling Center created the emotional healing support group to give us a safe place to begin to process our emotions and support each other as we heal emotionally while managing celiac disease and the resulting autoimmune disorders.
      The emotional healing support group meets every Thursday, 6:00-7:00pm, at the Jamestown Avenue Counseling Center of Baton Rouge. Jamestown Avenue Counseling Center is located at 4637 Jamestown Avenue, Baton Rouge, Suite B-1. Suite B-1 is upstairs.
      The support group is free and open everyone managing celiac disease. For more information: emotionalhealingforceliacs@hotmail.com
    • March 24, 2019 Until March 27, 2019
      NEW ORLEANS GOURMET GLUTEN-FREE mini GETAWAY    March 24 ~ 27, 2019   We have arranged a fun and Gluten-free food filled mini in the city known for it's food and fun.  We have arranged to eat many of the famous dishes that aren't usually Gluten-free at a few of the World Renown restaurants.   Staying at the Royal Sonesta Hotel on Bourbon Street in the center of the French Quarter, you'll be able to enjoy the ambiance of the city at all hours.   Our itinerary will include a Luxury Coach tour of the city and surrounding area - Admission to The National World War II Museum, including the Tom Hanks" 4D film "Beyond All Boundaries" - an exciting Airboat ride and tour through the Bayou.      This it the 3rd time we have visited New Orleans and it has always been well attended, so join us even if you've been there before.  Check out our website for the complete itinerary and cost.    Due to contractual obligations we must have 20 participants by October 31, 2018 to make this a go.      If you have any questions just give us a call at 410-939-3218.  Bob & Ruth info@bobandruths.com (410) 939-3218
    • March 30, 2019 Until March 31, 2019
      Nourished Festival is a family-friendly event with 10 locations across the US. Attendees will be able to sample food, health and beauty products, meet with companies, learn about the most current food lifestyles, receive coupons and attend educational sessions with industry experts. 
      Nourished Festival, managed by The Nourished Group and presented by Enjoy Life Foods, is the largest gluten-free, allergy-friendly and specialty diet event in the US, with 10 locations including.
      Managed by The Nourished Group, formerly The Gluten Free Media Group, The Nourished Festivals are the largest and fastest growing special diet consumer events in the United States. Started in 2007, the events have expanded from one to ten cities throughout the country. The festivals cater to anyone looking to lead a healthier lifestyle or those who follow a specialty diet due to autoimmune conditions, food sensitivities, allergies or intolerances. Offerings including Paleo, Keto, Plant-Based, Gluten-Free, Allergen-Friendly and Nut-Free products. The events provide the opportunity for attendees to sample and purchase new products, receive coupons, meet with brand ambassadors and attend educational classes with industry experts. For more information, visit http://www.nourishedfestival.com 
I know this is an older post but I am glad that I found this thread in an internet search. I am finally realizing that my months of vertigo are related to eating white rice hot cereal each morning. I even went to a vertigo specialist who did Epley Maneuvers which did not help.  When I took a break by eating grain-free and then resumed by eating a bowl of white rice hot cereal (hey, it’s comfort food for me), I had a bad spell of dizziness. The next day (still not making the connection), I a
  • Blog Entries

  • ×
    • Create New...