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Should I Request More Tests?

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Hello,

I was suspecting celiac disease and got these preliminary blood results from my PCP:

GLIADIN ANTIBODY (IGA): 14 U/mL

REFERENCE RANGE:

<11 NEGATIVE

11-17 EQUIVOCAL

>17 POSITIVE

GLIADIN ANTIBODY (IGG): 72 U/mL

REFERENCE RANGE:

<11 NEGATIVE

11-17 EQUIVOCAL

>17 POSITIVE

My PCP didn't order any other celiac panel tests, only those above, and referred me to a GI doctor. The GI doctor did not see that any further blood testing would be necessary, and scheduled a colonoscopy and upper endoscopy to confirm diagnosis. The results of the biopsy were perfectly normal, he said.

I asked him about the possibility of tissue transglutaminase testing, or a more specific test than just AGA, just to rule out celiac, but he said that because biopsy testing is the 'gold standard' for the disease, that no further testing is at all necessary. He said I can safely resume a normal, glutenous diet without worry.

But this does nothing to explain those high IgG levels. Should I force him to order additional testing? Or do I just assume I have leaky gut but not celiac?

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I would start the diet. Your IGG is a strong positive and endoscopies can have a false negative.


Courage does not always roar, sometimes courage is the quiet voice at the end of the day saying

"I will try again tommorrow" (Mary Anne Radmacher)

Diagnosed by Allergist with elimination diet and diagnosis confirmed by GI in 2002

Misdiagnoses for 15 years were IBS-D, ataxia, migraines, anxiety, depression, fibromyalgia, parathesias, arthritis, livedo reticularis, hairloss, premature menopause, osteoporosis, kidney damage, diverticulosis, prediabetes and ulcers, dermatitis herpeformis

All bold resoved or went into remission in time with proper diagnosis of Celiac November 2002

 Gene Test Aug 2007

HLA-DQB1 Molecular analysis, Allele 1 0303

HLA-DQB1 Molecular analysis, Allele 2 0303

Serologic equivalent: HLA-DQ 3,3 (Subtype 9,9)

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Yes, if you google ford gluten you get Dr. Ford's website and he explains why the antigliadin IgG is important.

(it means you are at least gluten intolerant, maybe even celiac, as the first thing rising in early celiac is often this test)


gluten-free since may 06 after neg. biopsy symptoms went away and DH symptoms which I had since 03 got gradually better.

daughter officially diagnosed celiac and casein intolerant.

non-DQ2 or DQ8. Maybe DQ1? Updated: Yes, double DQ5

Hypothyroid since 2000, thyroxine first started to work well 06 on a low-carb and gluten-free diet

Lost 20 kg after going gluten-free and weighing 53 kg now. neg. biopsy for DH. Found out afterwards from this forum that it should have been taken during an outbreak but it was taken two weeks after. vitaminD was 57 nmol/l in may08)

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