Jump to content
This site uses cookies. Continued use is acceptance of our Terms of Use and Privacy Policy. More Info... ×
  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.




  • Celiac.com Sponsor (A1):



    Celiac.com Sponsor (A1-M):


  • Get Celiac.com Updates:
    Help Celiac.com:
    eNewsletter
    Donate

Those Crazy Villi...


Emme999

Recommended Posts

Emme999 Enthusiast

I spoke with the pathologist/doctor today who viewed my endoscopy biopsies. She was *really* nice and even showed them to me under a microscope. It was really cool. The only un-cool part was that I couldn't see any villi! I said, "Where are they??" She just kind of grinned and said, "Exactly." Then she showed me a textbook picture of what they are supposed to look like. Mine were all sorts of funked up. It was kind of sad.

Anyway, she gave me a copy of the pathology report and it said the following:

COMMENTS:

Sections of the small bowel biopsy show extensive villous blunting ranging from moderate villous blunting to completely flat atrophic mucosa. Focal crypt hyperplasia is also identified. Only a rare intact villous structure is noted. Although a rare neutrophilic cryptitis is noted, the predominant inflammatory cell infiltrate is that of a mild to moderate mucosal intraepithelial lymphocytosis on the order of 25-40 lymphocytes per 100.

What the #*@^$?? :blink:

If anyone can decifer the lymphojargon, please do!

Thanks,

- Michelle :wub:

Link to comment
Share on other sites

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



Carriefaith Enthusiast

Don't worry I don't think it's anything bad, they are just "medical/scientific terms" for alterations in the intestinal wall due to gluten damage in celiacs. Open Original Shared Link

I believe that people with celiac who are eating gluten or just starting the diet have a lot of those crypts and intraepithelial lymphocytes. They should go away or there should be less of them with time.

25-40 lymphocytes per 100
those numbers should go down once you have been on the diet for a while.

I had to learn about some of this stuff for a seminar. I was giving a seminar on genetically modified foods and found that a certain kind of genetically modified potato (which wasn't put on the market thankfully) caused the same sort of intestinal damage (crypts and intraepithelial lymphocytes) in rats as in people with celiac disease. So I had to learn all of those crazy terms and then present them :blink:

Link to comment
Share on other sites
psawyer Proficient
COMMENTS:

Sections of the small bowel biopsy show extensive villous blunting ranging from moderate villous blunting to completely flat atrophic mucosa...  Only a rare intact villous structure is noted.

This is a clear, definite diagnosis of celiac disease. My endoscopy results were very similar. Given that, I would not worry too much about decoding the other obscure language. Many other conditions can be presented when celiac is present and gluten is still being ingested.

As I understand it, the lympho... language refers to the state of the immune system. Since celiac disease is an autoimmune disease, the presence of gluten in the diet triggers an elevated immune response. If you are newly gluten-free, I would not be concerned. If you still show hightened iummune activity levels after several months on the gluten-free diet, then I would look for possible other causes (or gluten still being ingested from an unrecognized source).

Link to comment
Share on other sites
lovegrov Collaborator

As others have said, it simply means you're showing an autoimmune response and you have celiac. The "lympho" language does not mean you have cancer, if that's what you're thinking.

richard

Link to comment
Share on other sites

Archived

This topic is now archived and is closed to further replies.


  • Celiac.com Sponsor (A19):



  • Member Statistics

    • Total Members
      120,460
    • Most Online (within 30 mins)
      7,748

    BrittanyH
    Newest Member
    BrittanyH
    Joined

  • Celiac.com Sponsor (A20):


  • Forum Statistics

    • Total Topics
      120.2k
    • Total Posts
      1m

  • Celiac.com Sponsor (A22):





  • Celiac.com Sponsor (A21):



  • Upcoming Events

  • Posts

    • shadycharacter
      Fermentation breaks down some of the gluten in wheat. Nowhere enough for a wheat dough to become gluten free, but the gluten may be significantly reduced. I think some pizzerias make the dough the day before and leave it overnight. The longer the microbes are acting on the flour, the better.
    • trents
      And the fact is, no two celiacs will necessarily respond the same to gluten exposure. Some are "silent" celiacs and don't experience obvious symptoms. But that doesn't mean no harm is being done to their gut. It just means it is subclinical. 
    • AlyO
      Thank you, Trents.  I appreciate your helpful and friendly reply. It seems more likely to be a bug.  It has been a pretty severe bought. I feel that I don’t have enough experience to know what signs my little one shows after exposure to gluten. 
    • trents
      Hannah24, be aware that if you are on a gluten free diet, you will invalidate any further testing for celiac disease (except genetics) and would need to go back to eating significant amounts of gluten for weeks or months to qualify for valid testing.
    • knitty kitty
      Hello, @Hannah24 Have you had a DNA test done?  Celiac Disease is genetic.  You must have at least one gene to develop celiac disease.  You don't have to be consuming gluten for a genetic test.   Anemia, diabetes and thiamine deficiency can cause false negatives.  Some lucky people are seronegative, but still have celiac disease.  Peripheral neuropathy, tingling in hands and feet are symptoms of vitamin deficiencies.  Vitamin C, Thiamine B1, Niacin B3, Pyridoxine B6, and Cobalamine B12 can each cause peripheral neuropathy.  These same vitamins are needed to produce blood cells.  Most undiagnosed Celiacs suffer from nutritional deficiencies. The DNA test would be helpful.
×
×
  • Create New...