Jump to content
This site uses cookies. Continued use is acceptance of our Terms of Use and Privacy Policy. More Info... ×
  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.




  • Celiac.com Sponsor (A1):



    Celiac.com Sponsor (A1-M):


  • Get Celiac.com Updates:
    Help Celiac.com:
    eNewsletter
    Donate

Did You Get A Negative Biopsy?


Newsy

Recommended Posts

Newsy Rookie

Here is the link:

Open Original Shared Link

Limited Formalin Exposure May Impair Disease Diagnosis

Last Updated: June 23, 2011.

Link to comment
Share on other sites
  • 2 weeks later...

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



jemms Apprentice

this is interesting...can you explain what this means in "lay language"? thanks so much, my brain glazed over once I got to the medical language. :blink:

Link to comment
Share on other sites
Skylark Collaborator

The article is about biopsy processing, but it says DH samples are fine in formalin. I'm not sure I see the relevance for celiac DH biopsies, and GI biopsies are not usually immunologically tested. Unfortunately I can't get the full text.

Link to comment
Share on other sites
Newsy Rookie

I am going to print & take to my derm dr. Appt. In August.

I thought it was interesting that they tested samples of DH, for one thing. I mean, of all the potential disease diagnoses out there, potentially verified by this type of testing.

Secondly, it seemed to me they were saying, for DH anyway, that a period of longer than 10 minutes in the "formulin" might possibly alter the specimen and resulting diagnosis.

I am not sure of all the possible implications for us regarding our testing and disease diagnosis confirmation with regard to this study,( I should know more after my appt.) but I had to wonder given the fact that DH samples were chosen for the study.

As I said, my DH has not been confirmed, but I will make sure to tell the doc in August not to leave my biopsy specimen in that solution for longer than 10 minutes ;)

Ps: does the biopsy hurt?

Link to comment
Share on other sites
Timothy Noel Newbie

After a blood test in Dec 2008, I was told that I have a 'wheat allergy'. I was a 2 (out of 4) in the immunoglobulin

Link to comment
Share on other sites
jemms Apprentice

how do they do a DH biopsy?

Link to comment
Share on other sites
WestyPDX Newbie

Ps: does the biopsy hurt?

Yes, but the pain is over fairly quickly. It's about twice as painful as a standard blood draw, but lasts a bit longer. It's been a long time since I had mine, so I forget if they give you a shot of local anesthetic or just rub a numbing cream over the biopsy area first.

how do they do a DH biopsy?

They do a punch biopsy using a bladed instrument to cut through the epidermis and dermis layers. The Mayo Clinic's site has a good drawing of one:

Open Original Shared Link

Mine required a few stitches.

Verdict: If this is what you have to go through to get treatment for your DH, by all means do it regardless of the pain and inconvenience. My diagnosis and treatment was a game changer for me.

Link to comment
Share on other sites

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



Newsy Rookie

Thank you for the link and info on the biopsy, Westy, but...OUCH!!! :unsure:

It sure doesn't look like fun, that's for sure.

Also, a few more questions for those experienced with the biopsy. I have been gluten free (including now all topical sources of gluten, like lotions, hair products, etc). Will that potentially affect my biopsy/diagnosis? Is it like the intestinal biopsy, where one must be EATING gluten for a positive result? My rash is getting much better now, and by the time my Dr. appt. rolls around, it may be nothing more than scars. Now, I will say this, it is fairly easy to get the rash active, with any gluten-containing lotion and the like.

I would hate to be turned away, and made to come back after either eating glutenband or putting it on my body to activate the rash.

Has anyone been diagnosed from scarring after the active rash has dissipated? My scarring is very...distinctive.

Thanks!

Link to comment
Share on other sites

Archived

This topic is now archived and is closed to further replies.


  • Celiac.com Sponsor (A19):



  • Member Statistics

    • Total Members
      120,466
    • Most Online (within 30 mins)
      7,748

    CtoThaE
    Newest Member
    CtoThaE
    Joined

  • Celiac.com Sponsor (A20):


  • Forum Statistics

    • Total Topics
      120.2k
    • Total Posts
      1m

  • Celiac.com Sponsor (A22):





  • Celiac.com Sponsor (A21):



  • Upcoming Events

  • Posts

    • knitty kitty
      Welcome to the forum, @LimpToeTheTimeless Bone growth plates close in the late teens to early twenties, so it's doubtful you'll grow much taller, but you may start to bulk up in muscle.  Remember to boost your absorption of vitamins and minerals needed to build muscle by eating a nutritionally dense diet and supplementing with essential vitamins and minerals, especially Thiamine B1, to counteract the malabsorption caused by Celiac Disease. Keep us posted on your progress! References: The effects of endurance training and thiamine supplementation on anti-fatigue during exercise https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4241913/ A functional evaluation of anti-fatigue and exercise performance improvement following vitamin B complex supplementation in healthy humans, a randomized double-blind trial https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542023/
    • B1rdL0ver
    • shadycharacter
      Fermentation breaks down some of the gluten in wheat. Nowhere enough for a wheat dough to become gluten free, but the gluten may be significantly reduced. I think some pizzerias make the dough the day before and leave it overnight. The longer the microbes are acting on the flour, the better.
    • LimpToeTheTimeless
      I am M 21 and I diagnosed myself after a week of fasting and slowly reintroducing stuff in my diet except gluten, I had terrible eczema scars ,dandruff and brain fog, now I am free after 6 years of just pain, I am 6'2, will I grow taller? And since I am a gymnast will my muscles grow like quicker, cause before no matter how effort I put in I just couldn't. 
    • trents
      And the fact is, no two celiacs will necessarily respond the same to gluten exposure. Some are "silent" celiacs and don't experience obvious symptoms. But that doesn't mean no harm is being done to their gut. It just means it is subclinical. 
×
×
  • Create New...