• Announcements

    • admin

      Frequently Asked Questions About Celiac Disease   09/30/2015

      This Celiac.com FAQ on celiac disease will guide you to all of the basic information you will need to know about the disease, its diagnosis, testing methods, a gluten-free diet, etc.   Subscribe to Celiac.com's FREE weekly eNewsletter   What are the major symptoms of celiac disease? Celiac Disease Symptoms What testing is available for celiac disease?  Celiac Disease Screening Interpretation of Celiac Disease Blood Test Results Can I be tested even though I am eating gluten free? How long must gluten be taken for the serological tests to be meaningful? The Gluten-Free Diet 101 - A Beginner's Guide to Going Gluten-Free Is celiac inherited? Should my children be tested? Ten Facts About Celiac Disease Genetic Testing Is there a link between celiac and other autoimmune diseases? Celiac Disease Research: Associated Diseases and Disorders Is there a list of gluten foods to avoid? Unsafe Gluten-Free Food List (Unsafe Ingredients) Is there a list of gluten free foods? Safe Gluten-Free Food List (Safe Ingredients) Gluten-Free Alcoholic Beverages Distilled Spirits (Grain Alcohols) and Vinegar: Are they Gluten-Free? Where does gluten hide? Additional Things to Beware of to Maintain a 100% Gluten-Free Diet What if my doctor won't listen to me? An Open Letter to Skeptical Health Care Practitioners Gluten-Free recipes: Gluten-Free Recipes
1 1
  • entries
  • comments
  • views

Positive Ttg, Negative Biopsy



This is a pretty good article that explains the December 2010 research on people with positive blood tTG or EMA blood tests and negative or Marsh 1 biopsy and its implications. Basically, because people with positive bloodwork and negative biopsy have the same metabolic markers as celiacs with full villous atrophy. The researchers recommend a gluten-free diet if you're positive on tTG or EMA, even if your biopsy is completely normal.

Here is the Pubmed link to the original abstract.

In the paper it explains the potential celiacs as: "Patients with potential celiac disease were all positive for anti-tissue transglutaminase antibodies (tTGA); all but one were also EmA positive; histological examination revealed an apparently normal mucosa (Marsh 0) in 9 subjects, just an increase in intraepithelial lymphocytes (Marsh 1) in 12 and increased intraepithelial lymphocytes coupled with crypt hyperplasia (Marsh 2) in 8 patients."


Recommended Comments

There are no comments to display.

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now