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Celiac Disease & Gluten-Free Diet Blogs

  • kareng's Blog
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  • Research on South African Celiac Tours
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  • Keating's Not-so-Glutenfree life
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  • Searchin for a Primary Care Dr. In Redlands That is Knowledgeable about Celiac disease
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  • Michael Fowler's Blog
  • Living in Japan with Ceoliac Disease
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  • HONG KONG GLUTEN, WHEAT FREE PRODUCTS
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  • SMAS: www.celiac.com
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  • JillianC
  • Sugar's Blog
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  • Gluten-Free Sisters :)
  • Eab12's Celiac Blog
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  • Newly Self Diagnosed?
  • misscorpiothing's Blog
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  • Petroguy
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  • Soap Opera Central
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  • Mr J's Blog
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  • CAC's Blog
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  • Teri Kiefer's Blog
  • happyasabeewithceliac's Blog
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  • Cheryl
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  • Colleen's blog
  • DawnJ's Blog
  • Gluten Challenge
  • twins2's Blog
  • just trying to feel better's Blog
  • Celiac Teen
  • MNBelle blog
  • Gabe351's Blog
  • moosemalibu's Blog
  • Coeliac Disease or Coeliac Sprue or Non Tropical Sprue
  • karalto's Blog
  • deacon11's Blog
  • Nyxie's Blog
  • Swpocket's Blog
  • threeringfilly's Blog
  • Madison Papers: Living Gluten-Free in a Gluten-Full World
  • babinsky's Blog
  • prettycat's Blog
  • Celiac Diagnosis at Age 24 months in 1939
  • Sandy R's Blog
  • mary m's Blog
  • Jkrupp's Blog
  • Oreo1964's Blog
  • keyboard
  • Louisa's Blog
  • Guts & Brains
  • Gluten Free Betty
  • Jesse'sGirl's Blog
  • NewMom's Blog
  • Connie C.'s Blog
  • garden girl's Blog
  • april anne's Blog
  • 4xmom's Blog
  • benalexander60's Blog
  • missmyrtle's Blog
  • Jersey Shore wheat no more's Blog
  • swezzan's Blog
  • aheartsj's Blog
  • MeltheBrit's Blog
  • glutenfreecosmeticcounter
  • Reasons Why Tummy tuck is considered best to remove unwanted belly fat?
  • alfgarrie's Blog
  • SmidginMama's Blog
  • lws' Blog
  • KMBC2014's Blog
  • Musings and Lessons Learned
  • txwildflower65's Blog
  • Uncertain
  • jess4736's Blog
  • deedo's Blog
  • persistent~Tami's Blog
  • Posterboy's Blog
  • jferguson
  • tiffjake's Blog
  • KCG91's Blog
  • Yolo's Herbs & Other Healing Strategies
  • scrockwell's Blog
  • Sandra45's Blog
  • Theresa Marie's Blog
  • Skylark's Blog
  • JessicaB's Blog
  • Anna'sMommy's Blog
  • Skylark's Oops
  • Jehovah witnesses
  • Celiac in Seattle's Blog
  • March On
  • honeybeez's Blog
  • The Liberated Kitchen, redux
  • onceandagain's Blog
  • JoyfulM's Blog
  • keepingmybabysafe's Blog
  • To beer, with love...
  • nana b's Blog
  • kookooto's Blog
  • SunnyJ's Blog
  • Mia'smommy's Blog
  • Amanda's Blog
  • jldurrani's Blog
  • Why choosing Medical bracelets for women online is the true possible?
  • Carriefaith's Blog
  • acook's Blog
  • REAGS' Blog
  • gfreegirl0125's Blog
  • Gluten Free Recipes - Blog
  • avlocken's Blog
  • Thiamine Thiamine Thiamine
  • wilbragirl's Blog
  • Gluten and Maize-Free (gluten-free-MF)
  • Elimination Diet Challenge
  • DJ 14150
  • mnsny's Blog
  • Linda03's Blog
  • GFinDC's Blog
  • Kim UPST NY's Blog
  • cmc's Blog
  • blog comppergastta1986
  • JesikaBeth's Blog
  • Melissa
  • G-Free's Blog
  • miloandotis' Blog
  • Confessions of a Celiac
  • Know the significance of clean engine oil
  • bobhayes1's Blog
  • Robinbird's Blog
  • skurtz's Blog
  • Olivia's Blog
  • Jazzdncr222's Blog
  • Lemonade's Blog
  • k8k's Blog
  • celiaccoach&triathlete's Blog
  • Gluten Free Goodies
  • cherbourgbakes.blogspot.com
  • snow dogs' Blog
  • Rikki Tikki's Blog
  • lthurman1979's Blog
  • Sprue that :)'s Blog
  • twinkletoes' Blog
  • Ranking the best gluten free pizzas
  • Gluten Free Product
  • Wildcat Golfer's Blog
  • Becci's Blog
  • sillyker0nian's Blog
  • txplowgirl's Blog
  • Gluten Free Bread Blog
  • babygoose78's Blog
  • G-freegal12's Blog
  • kelcat's Blog
  • Heavy duty 0verhead crane
  • beckyk's Blog
  • pchick's Blog
  • NOT-IN-2gluten's Blog
  • PeachPie's Blog
  • Johny
  • Breezy32600's Blog
  • Edgymama's Gluten Free Journey
  • Geoff
  • audra's Blog
  • mfrklr's Blog
  • 2 chicks
  • I Need Help With Bread
  • the strong one has returned!
  • sabrina_B_Celiac's Blog
  • Gluten Free Pioneer's Blog
  • Theanine.
  • The Search of Hay
  • Vanessa
  • racecar16's Blog
  • JCH13's Blog
  • b&kmom's Blog
  • Gluten Free Foodies
  • NanaRobin's Blog
  • mdrumr8030's Blog
  • Sharon LaCouture's Blog
  • Zinc, Magnesium, and Selenium
  • sao155's Blog
  • Tabasco's Blog
  • Amanda Smith
  • mmc's Blog
  • xphile1121's Blog
  • golden exch
  • kerrih's Blog
  • jleb's Blog
  • RUGR8FUL's Blog
  • Brynja's Grain Free Kitchen
  • schneides123's Blog
  • Greenville, SC Gluten-Free Blog
  • ramiaha's Blog
  • Kathy P's Blogs
  • rock on!'s Blog
  • Carri Ninja's Blog
  • jerseygirl221's Blog
  • Pkhaselton's Blog
  • Hyperceliac Blog
  • abbiekir's Blog
  • Lasister's Thoughts
  • bashalove's Blog
  • Steph1's Blog
  • Etboces
  • Rantings of Tiffany
  • GlutenWrangler's Blog
  • kalie's Blog
  • Mommy Of A Gluten Free Child
  • ready2go's Blog
  • Maureen
  • Floridian's Blog
  • Bobbie41972's Blog
  • Everyday Victories
  • Intolerance issue? Helpppp!
  • Feisty
  • In the Beginning...
  • Cheri46's Blog
  • Acne after going gluten free
  • sissSTL's Blog
  • Elizabeth19's Blog
  • LindseyR's Blog
  • sue wiesbrook's Blog
  • I'm Hungry's Blog
  • badcasper's Blog
  • M L Graham's Blog
  • Wolicki's Blog
  • katiesalmons' Blog
  • CBC and celiac
  • Kaycee's Blog
  • wheatisbad's Blog
  • beamishmom's Blog
  • Celiac Ninja's Blog
  • scarlett54's Blog
  • GloriaZ's Blog
  • Holly F's Blog
  • Jackie's Blog
  • lbradley's Blog
  • TheSandWitch's Blog
  • Ginger Sturm's Blog
  • The Struggle is Real
  • whataboutmary's Blog
  • JABBER's Blog
  • morningstar38's Blog
  • Musings of a Celiac
  • Celiacchef's Blog
  • healthygirl's Blog
  • allybaby's Blog
  • MGrinter's Blog
  • LookingforAnswers15's Blog
  • Lis
  • Alilbratty's Blog
  • 3sisters' Blog
  • MGrinter's Blog
  • Amanda
  • felise's Blog
  • rochesterlynn's Blog
  • mle_ii's Blog
  • GlamourGetaways' Blog
  • greendog's Blog
  • Tabz's Blog
  • Smiller's Blog
  • my vent
  • newby to celiac?'s Blog
  • siren's Blog
  • myraljo's Blog
  • Relieved and confused
  • carb bingeing
  • scottish's Blog
  • maggiemay832's Blog
  • Cristina Barbara
  • ~~~AnnaBelle~~~'s Blog
  • nikky's Blog
  • Suzy-Q's Blog
  • mfarrell's Blog
  • Kat-Kat's Blog
  • Kelcie's Blog
  • cyoshimit's Blog
  • pasqualeb's Blog
  • My girlfriend has celiacs and she refuses to see a doctor
  • Ki-Ki29's Blog
  • mailmanrol's Blog
  • Sal Gal
  • WildBillCODY's Blog
  • Ann Messenger
  • aprilz's Blog
  • the gluten-free guy
  • gluten-free-wifey's Blog
  • Lynda MEADOWS's Blog
  • mellajane's Blog
  • Jaded's Celiac adventures in a non-celiac world.
  • booboobelly18's Blog
  • Dope show
  • Classic Celiac Blog
  • Keishalei's Blog
  • Bada
  • Sherry's blurbs
  • addict697's Blog
  • MIchael530btr's Blog
  • Shawn C
  • antono's Blog
  • Undiagnosed
  • little_d's Blog
  • Gluten, dairy, pineapple
  • The Fat (Celiac) Lady Sings
  • Periomike
  • Sue Mc's Blog
  • BloatusMaximus' Blog
  • It's just one cookie!
  • Kimmy
  • jacobsmom44's Blog
  • mjhere's Blog
  • tlipasek's Blog
  • You're Prescribing Me WHAT!?!
  • Kimmy
  • nybbles's Blog
  • Karla T.'s Blog
  • Young and dealing with celiacs
  • Celiac.com Podcast Edition
  • LCcrisp's Blog
  • ghfphd's allergy blog
  • https://www.bendglutenfree.com/
  • Costume's and GF Life
  • mjhere69's Blog
  • dedeadge's Blog
  • CeliacChoplin
  • Ravenworks' Blog
  • ahubbard83's Blog
  • celiac<3'sme!'s Blog
  • William Parsons
  • Gluten Free Breeze (formerly Brendygirl) Blog
  • Ivanna44's Blog
  • Daily Life and Compromising
  • Vonnie Mostat
  • Aly'smom's Blog
  • ar8's Blog
  • farid's Blog
  • Sandra Lee's Blog
  • Demertitis hepaformis no Celac
  • Vonnie Mostat, R.N.
  • beetle's Blog
  • Sandra Lee's Blog
  • carlyng4's Blog
  • totalallergyman's Blog
  • Kim
  • Vhips
  • twinsmom's Blog
  • Newbyliz's Blog
  • collgwg's Blog
  • Living in the Gluten Free World
  • lisajs38's Blog
  • Mary07's Blog
  • Treg immune celsl, short chain fatty acids, gut bacteria etc.
  • questions
  • A Blog by Yvonne (Vonnie) Mostat, RN
  • ROBIN
  • covsooze's Blog
  • HeartMagic's Blog
  • electromobileplace's Blog
  • Adventures of a Gluten Free Mom
  • Fiona S
  • bluff wallace's Blog
  • sweetbroadway's Blog
  • happybingf's Blog
  • Carla
  • jaru24's Blog
  • AngelaMH's Blog
  • collgwg's Blog
  • blueangel68's Blog
  • SimplyGF Blog
  • Jim L Christie
  • Debbie65's Blog
  • Alcohol, jaundice, and celiac
  • kmh6leh's Blog
  • Gluten Free Mastery
  • james
  • danandbetty1's Blog
  • Feline's Blog
  • Linda Atkinson
  • Auntie Lur: The Blog of a Young Girl
  • KathyNapoleone's Blog
  • Gluten Free and Specialty Diet Recipes
  • Why are people ignoring Celiac Disease, and not understanding how serious it actually is?
  • miasuziegirl's Blog
  • KikiUSA's Blog
  • Amyy's Blog
  • Pete Dixon
  • abigail's Blog
  • CHA's Blog
  • Eczema or Celiac Mom?'s Blog
  • Thoughts
  • International Conference on Gastroenterology
  • Deedle's Blog
  • krackers' Blog
  • cliniclfortin's Blog
  • Mike Menkes' Blog
  • Juanita's Blog
  • BARB OTTUM
  • holman's Blog
  • It's EVERYWHERE!
  • life's Blog
  • writer ann's Blog
  • Ally7's Blog
  • Gluten Busters: Gluten-Free Product Alerts by Celiac.com
  • K Espinoza
  • klc's Blog
  • Pizza&beer's Blog
  • CDiseaseMom's Blog
  • sidinator's Blog
  • Dr Rodney Ford's Blog
  • How and where is it safe to buy cryptocurrency?
  • lucedith's Blog
  • Random Thoughts
  • Kate
  • twin#1's Blog
  • myadrienne's Blog
  • Nampa-Boise Idaho
  • Ursa Major's Blog
  • bakingbarb's Blog
  • Does Celiac Cause Sensitivites To Rx's?
  • delana6303's Blog
  • psychologygrl25's Blog
  • Alcohol and Celiac Disease
  • How do we get it???
  • cooliactic_BOOM's Blog
  • GREAT GF eating in Toronto
  • Gluten-free Food Recommendations!
  • YAY! READ THIS!!
  • BROW-FREE DIET BLOG
  • carib168's Blog
  • A Healing Kitchen
  • Shawn s
  • AZ Gal's Blog
  • mom1's Blog
  • The Beginning - The Diagnosis
  • PeweeValleyKY's Blog
  • solange's Blog
  • Cate K's Blog
  • Layered Vegetable Baked Pasta (gluten-free Vegetarian Lasagna)
  • Gluten Free Teen by Ava
  • mtdawber's Blog
  • sweeet_pea's Blog
  • DCE's Blog
  • Infertility and Celiac Disease
  • What to do in the Mekong Delta in 1 Day?
  • glutenfreenew's Blog
  • Living in the Garden of Eden
  • toddzgrrl02's Blog
  • redface's Blog
  • Gluten Free High Protein
  • Ari
  • Great Harvest Chattanooga's Blog
  • CeliBelli's Blog
  • Aboluk's Blog
  • redface's Blog
  • Being in Control of Your Gluten-Free Diet on a Cruise Ship
  • jayshunee's Blog
  • lilactorgirl's Blog
  • Yummy or Yucky Gluten-Free Foods
  • Electra's Blog
  • Cocerned husband's Blog
  • lilactorgirl's Blog
  • A Little History - My Celiac Disease Diagnosis
  • How to line my stomach
  • sewfunky's Blog
  • Oscar's Blog
  • Chey's Blog
  • The Fun of Gluten-free Breastfeeding
  • Dawnie's Blog
  • Sneaky gluten free goodness!
  • Chicago cubs shirts- A perfect way of showing love towards the baseball team!
  • Granny Garbonzo's Blog
  • GFzinks09's Blog
  • How do I get the Celiac.com podcast on my mp3 player?
  • quantumsugar's Blog
  • Littlebit's Blog
  • Kimberly's Blog
  • Dayz's Blog
  • Swimming Breadcrumbs and Other Issues
  • Helen Burdass
  • celiacsupportnancy's Blog
  • Life of an Aggie Celiac
  • kyleandjra.jacobson's Blog
  • Hey! I'm Not "Allergic" to Wheat!
  • FoOdFaNaTic's Blog
  • Wendy Cohan, RN's Gluten-Free and Dairy-Free Cooking Classes
  • Lora Derry
  • Dr. Joel Goldman's Blog
  • The Ultimate Irony
  • Lora Derry
  • ACK514's Blog
  • katinagj's Blog
  • What Goes On, Goes In (Gluten in Skin Care Products)
  • What’s new in hydraulic fittings?
  • cannona3's Blog
  • citykatmm's Blog
  • Adventures in Gluten-Free Toddling
  • tahenderson67's Blog
  • The Dinner Party Drama—Two Guidelines to Assure a Pleasant Gluten-Free Experience
  • What’s new in hydraulic fittings?
  • sparkybear's Blog
  • justbikeit77's Blog
  • To "App" or Not to "App": The Use of Gluten Free Product List Computer Applications
  • Onangwatgo
  • Raine's Blog
  • lalla's Blog
  • To die for Cookie Crumb Gluten-Free Pie Crust
  • DeeTee33's Blog
  • http://glutenfreegroove.com/blog/
  • David2055's Blog
  • Gluten-Free at the Fancy Food Show in San Francisco
  • Kup wysokiej jakości paszporty, prawa jazdy, dowody osobiste
  • Janie's Blog
  • Managing Hives & Gluten Allergies
  • Bogaert's Blog
  • Janie's Blog
  • RaeD's Blog
  • Dizzying Disclaimers!
  • Dream Catcher's Blog
  • PinkZebra's Blog
  • Hibachi Food and Hidden Gluten Hazards (How to Celebrate Gluten-Free)
  • jktenner's Blog
  • OhSoTired's Blog
  • PinkZebra's Blog
  • gluten-free Lover's Blog
  • Gluen Free Health Australia
  • Melissamb21's Blog
  • Andy C's Blog
  • halabackgirl9129's Blog
  • Liam Edwards' Blog
  • Celiac Disease in Africa?
  • Suz's Blog
  • Gluten-Free Fast Food
  • mis_chiff's Blog
  • gatakat's Blog
  • macocha's Blog
  • Newly Diagnosed Celiacs Needed for Study in Chicago
  • Poor Baby's Blog
  • the loonie celiac's Blog
  • jenlex's Blog
  • Sex Drive/Testosterone can be Depleted by Certain Foods
  • samantha79's Blog
  • 21 Months into the Gluten-free Diet
  • WashingtonLady's Blog-a-log
  • James S. Reid's Blog
  • Living with a Gluten-Free Husband
  • runner girl's Blog
  • kp3972's Blog
  • ellie_lynn's Blog
  • trayne91's Blog
  • Gluten-free Lipstick!
  • Nonna2's Blog
  • Schar Chocolate Hazelnut Bar (Gluten-Free)
  • pnltbox27's Blog
  • Live2BWell's Blog
  • melissajohnson's Blog
  • nvsmom's Blog
  • Diagnosed with Celiac Disease and Still Sick
  • snowcoveredheart's Blog
  • Gluten Free Nurse
  • Gluten-Free Frustration!
  • Melody A's Blog
  • novelgutfeeling's Blog
  • Trouble Eating Out Gluten-Free...Good or Bad?!
  • dilsmom's Blog
  • theceliachusband's Blog
  • amanda2610's Blog
  • Pancreas and Celiac Disease Link?
  • epiphany's Blog
  • Patty55's Blog
  • The Latest Gluten-Free Food Recalls
  • kenzie's blog
  • CVRupp's Blog
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Found 17 results

  1. Hi all, Are there any of you here who have this kind of histological finding Intraepithelial lymphocytosis with hyperplasia of the crypts and moderate atrophy of intestinal villi plus SIBO positive test METHANE? Kind regards
  2. Hi Guys, I am new here and i just wanted to say hello to everybody and to say thanks to all admins and people who are sharing info so they can help each-other! Today i need help for peace and mind I am male 39y old and Recently, couple months ago 6-8 i started to have more and more symptoms and problems for example like: constant bloating, constant discomfort, fatigue, weight loss and abdominal pain. I have hemmies and occasional blood in stool. I do not have D, sometimes i have C but normal stool. I went to my GI and he did upper and lower endoscopy with biopsy. Pathologists found increased IEL and moderate villious blunting Marsh 3a/b. My serology was negative for complete celiac panel. I did not do yet the gene testing. I was positive for SIBO (methane)and now i am on antibiotics. My other examinations are ok, (ultrasound, blood cbc, h.pylori stool, and so on). My questions are: 1. Does anybody here have positive biopsy and negative celiac panel even gene testing? 2. Does andbody have increased IEl and villious blunting with SIBO? Thank You and kind regards!

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  4. Hello there! I have already written on this site: https://www.celiac.com/forums/topic/157164-i-feel-so-bad/#comment-1100551. Now I would like to find out from someone who knows what is best for me to do and whether there is a way out of my situation at all. I'll start with the story: it all started 2 years ago when I had severe stress and helicobacter. Helicobacter was successfully treated for me a year ago. But after antibiotic therapy, I developed acne (pimples climb on corn, citrus fruits, and gluten-free oatmeal). So I spent almost a year on rice, potatoes, and boiled meat. Unfortunately, my body has stopped assimilating oils (margarine, vegetable oil, olive oil, I have not tried others). I have diarrhea from oils, my stomach rumbles very much on the left in the stomach area, bad breath, gases with the smell of hydrogen sulfide (the same symptoms from any fruits, berries, vegetables, even with a low fodmap content). I tried the therapy that was advised to me: I took vitamin D3, tanned, took magnesium citrate, but the vitamin B complex made my pimples crawl, and my stomach rumbled from L-glutamine. In general, it got better after therapy. Now in the hospital I have been diagnosed with sibo with the help of a breath test. The result is positive for lactulose, negative for fructose. I take rifaximin and vitamin B12, the rumbling has passed, but I am worried about the possibility of a relapse. How do I avoid it? And why do I feel so bad from oils and even teas, such as mint? How to populate the intestines with beneficial bacteria after sibo without causing sibo? And since I have chronic constipation, could you suggest something? I forgot to say that in a regular hospital I had an ultrasound with a load, and they found a dysfunction of the gallbladder. In a better hospital, they did it without any load. And I don't understand, does this sibo somehow affect the gallbladder or what? Sorry for having so much text and questions
  5. To Whom Ever Might Read This, This is triggered by some research Scott shared with me. Entitled "With age, insufficient tryptophan alters gut microbiota, increases inflammation" https://www.eurekalert.org/pub_releases/2021-06/mcog-wai062321.php And the very recent research I came across that shows Celiac disease (by monitoring our Microbiome) can be predicted up to 18 months in advance..... (Which I believe Scott will summarize soon as an article soon).....but this thread is more about the recent research I rediscovered on how LPS production triggering a Leaky gut can be triggered by Low B-Vitamins....and the accompanying research showing how each of the B-Vitamins (B1, B2, B3) play a role in controlling LPS production in our GI Tract... Entitled "Changes in gut microbiome in longitudinal study of infants precede onset of celiac disease" https://medicalxpress.com/news/2021-07-gut-microbiome-longitudinal-infants-onset.html 18 months in advance of a Celiac diagnosis is much earlier than you would suspect if Celiac disease is a 100 percent genetic disease (as they mused) surprising the researchers....but if SIBO or LPS production is the trigger for a leaky gut then.....it is what one might conclude if Low B-Vitamins are or could be the trigger.....what one might theorize...that your microbiome is triggering a Leaky gut.....(and why I have always argued that Celiac disease (and/or SIBO) if you believe SIBO can be a trigger for Celiac disease is a 50/50 proposition.....of your environment (IE Low B-Vitamins) affecting your genes... Proving to me, at least, that the genetic Celiac disease has an environment trigger....triggered, in part, by Low B-Vitamins. Here is the research that shows how B-Vitamins (B1 (Thiamine), B2 (Riboflavin) and B3 (Niacin) specifically) are involved in the regulation of LPS production in our GI tract leading, in time, to not only a Leaky Gut, but both SIBO and Celiac disease IMHO. For those who don't know or haven't studied it Liposaccharide aka LPS (and hereafter abbreviated LPS) is the portion of bacteria (known as a Endotoxin) thought to lead to a Leaky Gut in patients with SIBO.... The below research shows how Tryptophan, B1, B2 and B3 help down regulate the toxicity of LPS leading, in time, and with high enough (amounts) the toxicity (from LPS) can result in a Leaky Gut triggered by our Microbiome.... If low in any of these Vitamins or metabolites then you can develop SIBO and a leaky gut.....IMHO See this research entitled "Protective role of benfotiamine, a fat-soluble vitamin B1 analogue, in lipopolysaccharide (LPS)induced cytotoxic signals in murine macrophages" https://pubmed.ncbi.nlm.nih.gov/20219672/ See this research entitled "Riboflavin (aka Vitamin B2) protects mice against liposaccharide (LPS) induced shock through expression of heat shock protein 25" https://www.sciencedirect.com/science/article/abs/pii/S0278691510002474 See this research entitled "Niacinamide is a potent inhibitor of proinflammatory cytokines" https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1808598/ This would explain why Tryptophan has recently been shown to help heal Villi in Celiac's.... https://www.news-medical.net/news/20201022/Tryptophan-found-in-turkeys-can-accelerate-intestinal-healing-in-people-with-celiac-disease.aspx If any of these is true.....then it will take another 15 to 20 years (sadly) for the medical community to "Catch UP" with this latest medical research. The research on Niacin alone is 18+ years old..... And why they only "theorized" this.....much more recent research I found is less than 5 year old.....confirming these findings (as well as the new Tryptophan research) Entitled "Niacin (aka Niacinamide or Vitamin B3) and its metabolites as master regulators of Macrophage activation" https://www.sciencedirect.com/science/article/abs/pii/S0955286316302960 Where they note "This study reveals for the first time that niacin and its metabolites possess antioxidant, reprogramming and antiinflammatory properties on human primary monocytes and monocyte-derived macrophages." Which if the above research on B-Vitamins is correct trigger a Leaky gut when all these B-Vitamins (B1, B2, B3 and Tryptophan) get low and we get over run with the LPS endotoxin common in SIBO and other leaky gut syndrome(s) which include Celiac disease....etc. We now SIBO can be trigger for Celiac disease because people still struggling on a gluten free diet get better once their SIBO has also been treated. See this article about this topic... They concluded quoting... "The researchers conclude that SIBO affects most celiacs who have persistent gastrointestinal symptoms after going gluten-free." My argument is to treat the underlying trigger for Both.....Low B-Vitamins! I welcome anyone's feedback and insights? I hope this is helpful but it is not medical advice. Posterboy,
  6. How Low B Vitamins can Trigger a Celiac diagnosis and be Mistaken for a Genetic Disease To Whomever May Read This, (Thank you for taking the time to read it and I hope it helps you the way it did me! and if it does tell others....is all I ask)....because I know there are many more fellow sufferers still looking for answers... (because many/most B-Vitamin deficiencies up to 80 percent of the time (especially a Thiamine Deficiency) is going undiagnosed or misdiagnosed in other diseases)....and probably a Riboflavin Deficiency too because they occur together.... Read the blog post and you will see what I mean.... Note: this Posterboy blog post will have 2 portions…. A high level summary and an Appendix/Addendum list of available resources that support these suppositions… Depending on whether you have read the other Posterboy blog post(s) will determine how you want to read this one…. If this is your first then read it all…IF you have read other Posterboy blog posts…then just jump to the Appendix where the references/additional resources are….and all the dirty details... The Posterboy blog post starts now…entitled "How Low B Vitamins can Trigger a Celiac diagnosis and be Mistaken for a Genetic Disease" For a while now (10 to 12+ years now)…..I have been studying B-Vitamins to see what role if any they (B-Vitamins) might have in regulating our Immune System and if they could be the trigger for my GI problems or could have been mistaken for my Celiac disease diagnosis…. Note: I did not say my Celiac disease….but my diagnosis as a Celiac….see Appendix for other possible triggers. I had written two previous articles/Posterboy blog posts one about Thiamine (Beri Beri) aka Vitamin B1 and one about Niacin (Pellagra) aka Vitamin B3. Provided here for easy reference.....if you want to go back and read them sometime... Both play a critical role in our immune system and down regulate inflammation pathways in the body… This Posterboy blog post/article unites the two into an "Elegant Theory" of how and why these occur together in Celiac disease. I had previously done an unpublished article/blog post on Riboflavin….which I might share in the future (but probably not at this point) This Posterboy blog post will serve as the argument (thesis) that Riboflavin deficiency is common in Celiac’s going commonly undiagnosed/misdiagnosed….much like the other B-Vitamin deficiencies of Thiamine (B1) and Niacin (B3) in Celiac’s. I have now found that it is a cascade of all three of these B-Vitamins and maybe 4 (beyond the scope of this blog post Vitamin B6)….. B1, B2, B3 work synergistically together to control inflammation in the body. I found first that Pellagra could be common in Celiac’s going undiagnosed/misdiagnosed…. Then I found that Beri Beri might also be the reason for Celiac’s thin Villi…. SO I had to write about it/that too!.....but no ONE Vitamin/Mineral answered all the questions…. So that made me think I could be wrong about the Pellagra question (in part) at least… IF there is NO SKIN issues IE DH with your Celiac diagnosis then you have NOT YET developed Pellagra…. but more appropriately Pellagra Sine Pellagra…..or Pellagra without skin issues…. And brings me to the point of my current Posterboy blog post. I believe that most Celiac’s have developed Pellagra Sine Pellagra. Now granted they developed Beri Beri FIRST….because B-Vitamin deficiencies NEVER happen alone…. It (Celiac disease) is a sequalae (aftermath) of B-Vitamin deficiencies…and possibly some Minerals like Magnesium and Zinc and Copper etc….(Again beyond the scope of this post) See this Posterboy blog post to see how nutrients (IE Vitamin and Mineral Deficiencies), Genetics and your Environment (STRESS) interact…. To produce disease… So how did I arrive at Pellagra Sine Pellagra instead of Pellagra or Beri Beri (only)…. Because you definitely develop Beri Beri (FIRST)…..why not continue on the Pellagra tack… There is a couple of distinguishing features between the two most notably the level of SKIN involvement…. Pellagra is a very VISUAL disease…..IF you don’t have DH or other Skin problems then you have not yet developed Clinical Pellagra…. But Pellagra Sine Pellagra a Riboflavin deficiency has all the same symptoms of Pellagra without the pervasive skin issues… Make no mistake about it….I had already developed Beri Beri first (horrible fatigue) and Peripheral Neuropathy etc…. They typically occur together…..because as noted earlier B-Vitamin deficiencies don’t occur alone… ONE will affect the others… And why I landed on B2 (Riboflavin) instead of B3 (Niacin)…. The 2nd clue was the pervasive Iron deficiency issues most Celiac’s develop. Is Notable that Iron Deficient Anemia aka IDA is very common in Celiac’s… And people have forgotten how Riboflavin aka Vitamin B2 plays an important role in Iron deficient anemia… https://pubmed.ncbi.nlm.nih.gov/31318024/ Riboflavin deficiency individuals often have fertility problems as well… I too had these same problems that got better after Riboflavin supplementation… Riboflavin again aka Vitamin B2 can cause people to have Hypothyroid problems…..which again was me three…. got better after Riboflavin supplementation… Reason number 4) Anxiety can be the first sign of a Riboflavin deficiency check that one off too! Reason number 5) Riboflavin is the trigger for a Homocysteine problem…..commonly diagnosed as MTHFR Gene defect…. https://chrismasterjohnphd.com/blog/2019/02/26/mthfr-just-riboflavin-deficiency/ Check, Check, Check, Check, Check….I had all the signs of a Riboflavin deficiency and the doctor’s missed them ALL! Not to mention the hallmark angular cheilitis (Leaky Lips) for years…..and the doctor could only recommend for/to me was to stop leaking my lips sooooooo much! ALL this symptom’s and more got better after supplementing with Riboflavin…. SO that is why I know Pellagra Sine Pellagra happened to me and is also happening in other Celiac’s going undiagnosed/Misdiagnosed. The Iron Deficient Anemia…..can be treated (in many if not most cases) with either/by treating your Low Stomach Acid or by taking Riboflavin and/or Copper. See this research entitled “Is achlorhydria (No Stomach Acid) an (independent) cause of iron deficiency anemia” https://pubmed.ncbi.nlm.nih.gov/25994564/ The answer was a resounding yes! So, I had developed low/NO stomach acid as the trigger for my Celiac/NCGS diagnosis… AND just what another intrepid research discovered/studied 35+ years ago and was promptly forgot and never believed….the more things change…the more they stay the same! See this research entitled “Gastric morphology and function in dermatitis herpetiformis (DH) and in Celiac disease” https://www.ncbi.nlm.nih.gov/pubmed/3992169 That should be the end of the discussion…..but It won't be....while their patients suffer...they will do more studies about it! Quoting the whole abstract for emphasis! Abstract “Gastric acid secretory capacity was evaluated in 116 patients with dermatitis herpetiformis by means of the pentagastrin test. Endoscopic gastric mucosal biopsy specimens were obtained from both the body and the antrum in 90 of them. Forty-eight patients (41%) had a maximal acid output less than 10 mmol/h, and 30 of them (26%) were achlorhydric. T he frequency of achlorhydria increased with age, and 27 out of 58 patients (47%) more than 50 years old were achlorhydric. Antrum-sparing chronic atrophic gastritis was present in 92% of the achlorhydric patients, and hypergastrinaemia and serum parietal cell antibodies were found in most of them. The prevalence of chronic gastritis of the body and of the antrum increased with age. There was no correlation between atrophic gastritis or achlorhydria and small-intestinal villous atrophy, the results of the D-xylose test, and blood folate and serum zinc determinations. The transferrin saturation index was lower in patients with achlorhydria. The frequency of achlorhydria was significantly higher in patients with dermatitis herpetiformis than in 69 patients with celiac disease.” Note: 90+ percent of Celiac’s have NO stomach acid (at all)….this is not counting the percent of Celiac’s where just Low in Stomach acid….mind you This was not in NCGS but a study of Celiac’s who were already diagnosed as Celiac’s…. But EVEN this is not enough to get some people to believe!!!! The research is out there…..this is a Classic example of Co-Morbidity….IE a Sequelae of one condition triggering the other! The aftermath of B-Vitamin and Mineral deficiencies of Zinc, Magnesium, B1 (Thiamine), B2 (Riboflavin), B3 (Niacin) and possibly Copper is being diagnosed as NCGS and/or as Celiac disease diagnosis IMHO! It is my hope by sharing this old research rediscovered that at least ONE other person will believe me (YOU) and be helped! Use a Celiac disease diagnosis as the way back. . . . not the end of the road for your health but the beginning of your way back to health! As the I have the Lord being my help! As I am fond of saying “To Educate is to truly free!” Where there is a free exchange of knowledge there is health and peace for one’s soul and body! So, what can I do NOW about this know that I know B-Vitamins might help my Celiac diagnosis? There is “No Formula” but this is the best advice I can offer you. Take a B-Complex AND a Benfotiamine (Fat Soluble B-1) or other Fat Soluble B-1s like AlliThiamine or Lipothiamine (harder to find) AND a Magnesium Citrate (with meals) or Magnesium Glycinate (anytime) 2x to 3x a day (with meals) for 3 to 6 months. (IF you are not taking an acid reducer like a PPI or H2 Blocker (better of the two kind with less long term side effects) ) you will begin to burp continuously even up to 2 hours after you have finished your meal….. and between meals with the smallest snack… producing the biggest BURPS you have had in years, and years. Don’t stop for at least 6 months….don’t stop taking them when you begin burping (again without bloating/gas distension) BUT continue for 6 months till BURPING without these other symptom’s and a regular movement will become your new normal. You are now again digesting proteins in your diet triggering a food allergy. What I didn’t know at the time was that Pellagra is a “Capstone” diagnosis and not the “Cornerstone” disease. Pellagra is definitely happening in Celiac’s because Tryptophan has been shown the ability to be a therapeutic for Celiac’s. See this research about it… https://www.eurekalert.org/pub_releases/2020-10/aaft-tri101920.php Here is another article about the same research indicating Tryptophan as Therapeutic treatment for Celiac’s… https://www.news-medical.net/news/20201023/Intestinal-microbiota-offers-new-prospects-for-treating-celiac-disease.aspx Confirming that when you develop “Leaky Gut Syndrome(s)” you have developed Pellagra. But Pellagra does not happen alone and is not the trigger….it is the combination of multiple B-Vitamin deficiencies beginning with Low Thiamine (B1), then Low B2 (Riboflavin) and finally Low Niacin (B3) aka Niacinamide presenting as DH in Celiac’s… I did not develop Pellagra but Sine Pellagra instead! Note: as to not overpower the reader (you) with too much information see addendum/appendix for more reference’s resource where you can read to your Heart’s content (as much) or as little as you need to help you understand these “Lost Connections” explaining how the Chicken came before the Egg (Diagnosis). First you develop Low B-Vitamin deficiencies (IE Thiamine deficiency or undiagnosed Beri Beri) THEN your Villi Thin and THEN you develop Pellagra Sine Pellagra a Riboflavin deficiency leading (in time) finally to a/your Celiac diagnosis! Also Note: SIBO and Cows Milk Protein IE Casein (not Lactose as is commonly believed) might also be a problem for you. See the Appendix for more details. 2 Timothy 2: 7 “Consider what I say; and the Lord give thee understanding in all things” this included. I hope this is helpful but it is not medical advice. Posterboy by the Grace of God, ADDENDUM/Appendix Resources Thiamine the Overlooked Vitamin That Improves Autoimmune Disease And Autonomic Dysfunction https://awaken.com/2021/02/the-overlooked-vitamin-that-improves-autoimmune-disease-and-autonomic-dysfunction/ The issues/symptoms of a Thiamine deficiency hide in other diseases…. It is only suspected (tested) for in diseases with high clinical suspicion such as Alcoholics and Anorexic’s etc…. Also here is a nice overview of how to recognize a Thiamine deficiency… https://healthprep.com/articles/fitness-nutrition/guide-symptoms-thiamine-deficiency/#:~:text=Weight loss may occur in a thiamine deficiency,individuals called AMP-activated protein kinase (AMPK) becomes impaired. Here is the best thread on a Thiamine deficiency and its many presentations/faces/symptoms on Celiac.com for more resources on Beri Beri in GI diseases like Celiac disease and IBS etc. Recently Celiac.com wrote an article linking AnitGAD antibodies to Celiac disease. So that set me out to see if there was a link between Gluten Ataxia and AntiGAD antibodies…. And it turns out AntiGAD antibodies are diagnostic confirmation of a Thiamine deficiency in Celiac’s manifesting themselves as Gluten Ataxia… See this research that explains the connection… entilted “Wernicke's encephalopathy: an excitotoxicity hypothesis” https://pubmed.ncbi.nlm.nih.gov/9346467/ This confirms exactly what is happening in other GI diseases like UC and Chrons. See this research entitled "Wernicke Encephalopathy in Crohn's disease and Ulcerative Colitis" https://www.sciencedirect.com/science/article/pii/S0899900721000447 AS if often the case in WE the treatment is too little too late….let's not let the same thing apply/happen to Celiac disease patients too! IF the research on UC and Chrons’ is to be believed Low Thiamine level’s can be a predictor of disease severity and recovery. NOW a similar study needs to be done to confirm my many years of research proving once and for all…. A Thiamine deficiency is the trigger for Thin Villi! Note: The Hormones Matter website is the best Thiamine resource on the web….and EON Health is a close second. Zonulin a Marker for Niacin deficiency Links/Resources https://alobar.livejournal.com/2930798.html#%2F2930798.html Dietary Tryptophan Enhanced the Expression of Tight Junction Protein ZO-1 in Intestine: Trp enhanced tight junction protein ZO-1… https://www.researchgate.net/publication/312962348_Dietary_Tryptophan_Enhanced_the_Expression_of_Tight_Junction_Protein_ZO-1_in_Intestine_Trp_enhanced_tight_junction_protein_ZO-1 Dietary l-tryptophan alleviated LPS-induced intestinal barrier injury by regulating tight junctions in a Caco-2 cell monolayer model https://pubmed.ncbi.nlm.nih.gov/30977499/ Intestinal permeability IE Leaky Gut and oxidative stress in patients with alcoholic pellagra (reversed with Niacinamide) https://pubmed.ncbi.nlm.nih.gov/16713031/ Which is what the latest research confirms Tryptophan can be used in Celiac’s to heal Villi https://www.news-medical.net/news/20201022/Tryptophan-found-in-turkeys-can-accelerate-intestinal-healing-in-people-with-celiac-disease.aspx Does Going Gluten Free Provide Relief or All Celiacs? The answer is NO! https://medicalxpress.com/news/2021-02-gluten-free-diets-cure-all-celiac-disease.html And why I recommended B-Vitamins as an adjunct treatment for Co-Morbidities that happen in Celiac’s. This a complimentary approach. See this Posterboy blog post that discusses the B-Vitamins that might help treat a Celiac diagnosis About 40 pct of Celiacs are NOT helped when they go gluten free. This is about what else someone can do that is still triggering Villi blunting when eating gluten fee is not enough to heal your Villi??? Three or four of the most common triggers (IMO) for continued GI inflammation (Issues) in IMO are Milk (Cows’ Milk Protein) aka CMP in the literature. See this great Celiac.com article about how Milk in peoples diet can also trigger Villi Blunting… A reaction to Cows Milk Protein (Casein) can happen in up to 40 percent of Celiac’s… See this nice study on the issue of Caseins’ also triggering an Immune response in Celiac’s Entitled “IgA anti-gliadin antibody immunoreactivity to food proteins IE Cows Milk Proteins” https://www.tandfonline.com/doi/full/10.1080/09540100400003204 You can just read the abstract and not surprising it is 15+ years old and only recently Celiac.com did an article on it….. people can’t wait another 15 years for the medical community to pick up on this connection and why I am writing this blog post NOW! 2) SIBO can happen in the Majority of Celiac’s Note: This study is about SIBO happening in Celiac’s already treated with a gluten free diet. Almost 2/3 of Celiac’s symptoms got better after treating their underlying causes for a Celiac diagnosis such as SIBO in this study. 3) B-Vitamins that become low when one has SIBO You will find this a common theme…..after treating Celiac disease…..continued symptoms continued until the underlying cause(s) like SIBO, Cows Milk, Low/NO stomach acid or Medicines keep triggering Villi blunting… I can only tell you it helped me to treat my underlying cause’s like Low Stomach Acid and my B-Vitamin deficiencies going undiagnosed as part of Celiac disease diagnosis. See this new research that verify this fact from 2020 just a year old…from Chicago University https://medicalxpress.com/news/2020-02-mouse-celiac-disease-treatments.html Where they note quoting “Even while maintaining a strict gluten-free diet, 40% of celiac disease patients still show signs of inflammation and villous atrophy, or damage to the villi, the small, finger-like protrusions in the small intestine that help absorb nutrients. Therefore, treatments that can reverse or prevent the disease are greatly needed to improve quality of life for people with celiac.” Tryptophan can do that. So can B1 (Thiamine), B2 (Riboflavin) and B3 (Niacin) if you can believe the latest research on this topic. Some of it is 15 or 20 years old now….and doctors are not aware of this groundbreaking research. 4) Low/NO Stomach Acid See this research discovered 30+ years ago entitled “Gastric morphology and function in dermatitis herpetiformis (DH) and in Celiac disease” https://www.ncbi.nlm.nih.gov/pubmed/3992169 Celiac’s are suffering now and can’t wait another 10 or 15 years before they rediscover this research on their own! I wrote a Posterboy blog post about this too about how Low/NO Stomach acid could be the trigger for a subsequent Non Celiac Gluten Sensitivity diagnosis aka NCGS ….but few people seemed to understand it… Recently PPIs use has shown to trigger a Celiac diagnosis…..and yet nonchalantly this research is minimized…. among other medicines that can also trigger Villi Blunting (Atrophy) with use… See this Celiac.com thread about it…how PPIs, NSAIDS and SSRIs use were found to be associated with Villi Atrophy and subsequent Celiac diagnosis. See also this thread about how some Blood Pressure Medicine might blunt your Villi…. Back to the discussion at hand….how Zonulin can be a biological marker for a Niacin deficiency… This is important because Niacin is used in Stomach Acid production…. Zonulin as a marker for a (Low) Niacin levels aka Deficiency confirms IMHO a metabolic trigger for Pellagra going undiagnosed in Celiac disease. The IJCD noted this association of Pellagra in Celiac’s in 2015…..where they noted the majority or 58 percent approximately of Celiac’s would be Co-Morbid with their Celiac disease. It just nobody has followed up on these associations…..because you can’t see Pellagra in people until Skin Rashes develop….. by then DH has been diagnosed as a symptom of Celiac disease and by then you are too late! Doctors can’t see how these two diseases are connected but researchers can……. and fellow sufferers who have suffered at the hands of Doctor’s ignorance of the 4 Ds of Pellagra…. They get a D+ on recognizing Pellagra, Beri and Beri and Pellagra Sine Pellagra in Celiac disease today! IT is no one’s fault….IT is the process. There are not good B-Vitamin tests to determine the status of B-Vitamin deficiencies in Celiac’s and other GI patients. The FIRST good study about this is the link I noted above that confirmed the SEVERITY of the Thiamine deficiency IE Beri Beri predicted the SEVERITY of UC and Chron’s patients! Provided here again for easy reference… See this research entitled "Wernicke Encephalopathy in Crohn's disease and Ulcerative Colitis" https://www.sciencedirect.com/science/article/pii/S0899900721000447 Why would we not think it would be the same for Celiac disease! And IF the research is to be believed low Zonulin levels are an indicator of Low Niacin levels aka Pellagra in it’s most severe presentation of perfuse Skin Lesions….being diagnosed as DH today! ETA: Found only this month (week) while writing this article/blog post Very recent research Circa 2021 also confirmed that eating gluten free alone does not heal all Celiac’s making supplementation with B-Vitamins (IMHO) and Magnesium, in part, an essential treatment for those suffering from inflammation not due to gluten! See this research entitled “Do gluten-free diets provide a cure-all for celiac disease” and the answer is unequivocally NO… In a subset of Celiac’s. https://medicalxpress.com/news/2021-02-gluten-free-diets-cure-all-celiac-disease.html Quoting their conclusion(s) A significant number of patients previously thought to be well-treated by a gluten-free diet may in fact require additional interventions to fully curb their gut inflammation. Don’t be surprised if takes another 10 or 15+ years of “more study” to confirm these findings! Each generation much pass on their knowledge to the next….or it soon becomes lost again… This is my humble attempt to pass on that knowledge. To quote Isaac Newton “I do not know what I may appear to the world, but to myself I seem to have been only like a boy playing on the seashore, and diverting myself in now and then finding a smoother pebble or a prettier shell than ordinary, whilst the great ocean of truth lay all undiscovered before me.” — Isaac Newton I did this first for myself…..with the hope that it might help others someday. 3 Blessed be God, even the Father of our Lord Jesus Christ, the Father of mercies, and the God of all comfort; 4 Who comforteth us in all our tribulation, that we may be able to comfort them which are in any trouble, by the comfort wherewith we ourselves are comforted of God. It is my sincerest hope that I was able to throw a few “Starfish” back. But I fear I have not helped enough! http://www.starrbrite.com/starfish.html The Starfish Story Original Story by: Loren Eisley "One day a man was walking along the beach when he noticed a boy picking something up and gently throwing it into the ocean. Approaching the boy, he asked, What are you doing? The youth replied, Throwing starfish back into the ocean. The surf is up and the tide is going out. If I don’t throw them back, they’ll die. Son, the man said, don’t you realize there are miles and miles of beach and hundreds of starfish? You can’t make a difference! After listening politely, the boy bent down, picked up another starfish, and threw it back into the surf. Then, smiling at the man, he said I made a difference for that one!" Part 4 Additional Resources Is COVID 19 primarily a GI disease first See this research entitled “Severe COVID19 Is Fueled by Disrupted Gut Barrier Integrity” https://www.medrxiv.org/content/10.1101/2020.11.13.20231209v1.full Is “Leaky Gut Syndrome” a sign of Vitamin/Mineral deficiency See this research entitled “Regulation of the intestinal barrier by nutrients (Nutrition): The role of tight junctions” https://onlinelibrary.wiley.com/doi/10.1111/asj.13357 And this one entitled Intestinal permeability and oxidative stress in patients with alcoholic pellagra https://pubmed.ncbi.nlm.nih.gov/16713031/ See also the is Live Journal article about how Zonulin can be a “Marker for Niacin Issues”….IE is Zonulin a sign of Pellagra going undiagnosed or Misdiagnosed as Celiac disease today! https://alobar.livejournal.com/2930798.html#/2930798.html I can also recommend this blog post on Zinc deficiency by Blue Sky
  7. To All, This for those who have a Sulfite allergy specifically. But I also creating this as a reference article for Molybdenum......and how It is important for us to "Detox" our body. Without it Oxidative Stress builds up in the body leading to inflammation and disease. Here are the references for anyone who has Sulfite Allergy or SIBO or a Candida (Yeast) Problem. https://www.thecandidadiet.com/molybdenum/ https://www.raggeduniversity.co.uk/2019/08/11/prospecting-document-molybdenum-adjunct-to-thiamine-therapy-in-relation-to-alcohol-use/ https://www.eonutrition.co.uk/post/got-sibo-here-s-why-you-need-to-get-your-thiamine-status-checked (And your Molybdenum levels checked) https://www.sciencedirect.com/topics/medicine-and-dentistry/molybdenum-deficiency Here is research on Molybdenum's possible role in Type 2 Diabetes... Entitled "Trace elements status in diabetes mellitus type 2: Possible role of the interaction between molybdenum and copper in the progress of typical complications" https://www.diabetesresearchclinicalpractice.com/article/S0168-8227(10)00604-2/fulltext Another on Molybdenum deficiency in wildlife leading to Diabetes like syndrome... Entitled "A syndrome of molybdenosis, copper deficiency, and type 2 diabetes in the moose population of south-west Sweden" https://pubmed.ncbi.nlm.nih.gov/10813452/ And because the Molybdenum/Copper ratio is important in Type 2 diabetes I am also including this article on Copper deficiency in Diabetes... Entitled "Effect of copper or insulin in diabetic copper-deficient rats" https://pubmed.ncbi.nlm.nih.gov/6344092/ I know I have had these deficiencies and after supplementing with them my health got better. See this Posterboy blog post about these Micronutrient deficiencies in Celiac's.... Every time I found I had a Vitamin deficiency.......the doctor's said it was RARE and I couldn't have one.... And every time I have supplemented with my "Rare" Missing Vitamin Deficiency my health has improved... I have found most Celiac's could be low in as many as 20+ Vitamin/Minerals.... It has been a long and winding road as they say.....but around each curve in the road (or set back in my health) I have found a Vitamin Deficiency going undiagnosed and supplement with it has helped it... See this research entitled "Copper deficiency as a cause of neutropenia in a case of Celiac disease" https://pubmed.ncbi.nlm.nih.gov/27635061/ It wasn't the Celiac disease that was the cause of the Nutropenia...it was the Copper deficiency that occurs in/with a Celiac diagnsois! I will quote the whole abstract because it is short! Abstract "We report a 17 year-old male patient, who presented with chronic diarrhoea, progressive pallor, short stature, anaemia (haemoglobin of 4.9 g/dL) and neutropenia and was diagnosed as coeliac disease. His neutropenia did not respond to 8 months of gluten-free diet, iron, folic acid and vitamin B12 therapy. So we suspected copper deficiency and his serum copper levels were tested, which was low. His neutrophil counts normalised after 2 months of copper supplementation. Hence we concluded that the cause of neutropenia in our case was copper deficiency." I am that "Male Patient" that they don't think could have a Copper deficiency.... My High Iron levels are from my Low Copper Status and probably my Low Molybdenum levels/status too! https://medicalxpress.com/news/2007-07-iron-copper-relationship.html#:~:text=Iron and copper relationship is studied. Hereditary hemochromatosis,body iron levels resulting from any medical condition And because Doctor's are not studying nutrition as a cause....when they see a nutrition problem....they can't understand....or haven't studied...it is pronounced as a "Genetic" Problem instead.... See this Polycythemia Vera thread for more details about why Cooper and Iron are related problems... I hope this is helpful but it is not medical advice. Posterboy,

  8. Celiac.com Sponsor (A8):
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  9. Celiac.com 04/30/2018 - Rosacea is one of the most common skin diseases, and usually manifests as chronic inflammation of the eyes and the central part of the face. Rosacea is medically harmless, but it can trigger strong self-consciousness and reduce people’s overall enjoyment of life. For most people, symptoms of rosacea include flushing and erythrosis or reddening of the face. A small percentage of patients also get the formation of papules and pustules, with phymata. Doctors have posited numerous possible triggers, including hypochlorhydria, dysmotility, anatomic anomalies of the intestine, and immunologic causes. SIBO is an acronym for small intestinal bacterial overgrowth, a medical condition marked by an abnormally high concentration of bacteria in the jejunal aspirate on culture. SIBO is more common in people with rosacea than it is in the general population, and when SIBO is treated with antibiotics, skin lesions vanish in nearly 100% of cases. This remission lasts for at least 9 months in about 80% of patients. The same thing happened when unresponsive SIBO patients receiving placebo as part of a study were switched to antibiotics, so the evidence is very strong. It’s well known that numerous patients with rosacea have stomach and gut complaints, including dyspepsia, bloating, flatulence, abdominal pain of a cramping nature, altered bowel habits such as alternating constipation and diarrhea, and meteorism. It’s also not uncommon for rosacea patients have to suffer from medical conditions such as ulcerative colitis, Crohn’s disease, celiac disease, gastritis due to H. pylori overgrowth, lipase deficiencies, hypochlorhydria, and diseases affecting the small intestinal mucosa. Rosacea patients show a good response to a variety of antibiotics, including tetracycline or macrolide drugs, metronidazole, or chloramphenicol. The overwhelmingly positive response to antibiotics, coupled with the fact that many rosacea patients see symptom improvement when treated with drugs that speed intestinal movement, lends support to the idea that skin lesions have a bacterial origin. Still, evidence of bacterial role in rosacea has been far from clear. Some researchers suspect that rosacea lesions result from increased intestinal permeability in patients with SIBO, which in turn might lead to translocation or pro-inflammatory cytokine release. Earlier studies have linked rosacea with certain genetic variants in the genomes of rosacea sufferers that were strongly associated with the disorder, including genetic variants in or near the HLA-DRA and BTNL2 genes. Interestingly, these areas of the genome are also associated with autoimmune disease, including type I diabetes and celiac disease. Read more about rosacea and SIBO at News-medical.net, and at Rosacea.org.
  10. To All, This is the thread I said I would start.... This analysis/opinion will turn on the neurotransmitter Acetylcholine. While it is well known Acetylcholine effects our CNS....it is less well know that Acetylcholine also performs the same function for the Parasympathetic Nervous System. https://en.wikipedia.org/wiki/File:1503_Connections_of_the_Parasympathetic_Nervous_System.jpg When we get low in Thiamine and subsequently Acetylcholine we lose the ability to control our bowels because our Vagus nerve in essence short circuits....and our body no longer can control it's organs connected to the Vagus Nerve leading to bowel problems associated with Celiac disease. IE a Vagus Nerve disorder develops once we get low in Thiamine..... Here is a nice over of how a Vagus nerve disorder can trigger issues with our Parasympathetic Nervous System. https://www.md-health.com/Vagus-Nerve.html I hope this is helpful but it is not medical advise. Posterboy,
  11. A Case for Thiamine Supplementation in Celiac’s IF only for a Season in Time I have been doing Posterboy blog posts every so often now for a while now to share my experience with supplementation. I have settled on the fact that many of the existing GI issues can triggered by existing nutritional deficiencies. ((I think most people must think I still take Niacinamide or Thiamine or a B-complex.....I do not now take any of these things. I only took them for a Season in Time and the reason for the name of this Posterboy blog post. For many taking an Enzymic B-Complex with Benfotiamine (preferably with Magnesium Glycinate or Magnesium Citrate with meals) for 3 to 6 months when taken with meals will be enough, for some 6 months or longer might be needed..... you decide the Season and the times that is best for you!)) See this research entitled “Nutritional inadequacies of the gluten free diet in both recently diagnosed and long term patients with celiac disease” https://pubmed.ncbi.nlm.nih.gov/23198728/ As I often note….. research is 5 or 10 years old (for whatever topic it is)…in this case that Thiamine is not only Low at diagnosis of a Celiac diagnosis…continuing to eat a gluten free diet without supplementation will make you even LOWER in Thiamine. This is not a case of the “Chicken or the Egg”….. a Thiamine deficiency comes FIRST….then you develop GI problems IMHO. This leads to an impaired Vagus Nerve response…. https://www.md-health.com/Vagus-Nerve.html I once thought this was a Niacin deficiency (and in part it still can be) but it begins with a Thiamine Deficiency first (beyond the scope of this Posterboy blog post)…..when one develops the skin condition of DH in/with their Celiac diagnosis…. the Celiac has gone onto to develop a Niacin deficiency. I never developed full blown Pellagra (beyond limited skin involvement) I did not develop symptom’s beyond Pellagra Sine Pellagra aka as a Riboflavin deficiency as noted by horrid Angular Cheiliitis (Leaky Lips)…. After extensive PMing back and forth with EnnisTx (I don’t think I ever told him) I realized….I had gotten the wrong diagnosis…. so from then I adjusted/iterated the model. I changed my opinions/mind about my conclusions…..and realized I had been wrong…. So that sent me back to the drawing board(s) so to speak…..if it wasn’t Pellagra what was it…. And I will skim over this portion because it is only an intermediate step in the process as noted above I had developed not Pellagra but Pellagra Sine Pellagra a Riboflavin deficiency. See this research entitled “Kynurenine pathway metabolites in humans: disease and healthy States” Here is the abstract to keep it on the lighter side…. https://pubmed.ncbi.nlm.nih.gov/22084578/ Once the Kynurenine Pathway breaks down…essentially your immune system goes haywire… Here is the more technical answer via their conclusion on the Kynurenine Pathway and disease states… “Conclusion The kynurenine pathway is an effective mechanism in modulating the immune response and in inducing immune tolerance. This is achieved by accelerating the degradation of tryptophan and the generation of kynurenines. The metabolites of the pathway, with their different inherent properties, can also synergize or antagonize the effects of one another. By measuring the levels of tryptophan, kynurenines and the K/T ratio under various pathological conditions, the degree of immune activation and the relationship between the kynurenine pathway and disease states may be gleaned. However, much research is still needed to fully understand the complex interaction between tryptophan, IDO and kynurenines among themselves and within the CNS and in the periphery. With the seemingly prevalent involvement of the kynurenine pathway in a wide range of different diseases and disorders, the knowledge gained from research focusing on the kynurenine pathway may be translated into designing novel and more effective treatment strategies.” I did not set out to learn this….but only set out for the truth of the matter. But from there I was able to back track and find out the trigger for this cascade… It was not B3 or B2 (not really) but B1….(Or lack thereof) that was the real trigger… I have been counting down B-Vitamins all this time….you might say I have been counting down to One! The combination of these B-Vitamins (B1, B2, B3) had been shown to down regulate inflammation in the body. See where this was recently studied in the mouse model for health entitled “Vitamin B combination (of B1, B2, B3) reduces fluconazole toxicity in Wistar rats” https://pubmed.ncbi.nlm.nih.gov/30903555/ And while they each work to down regulate inflammation…..together they are dynamite! But what was the Spark??? That creates the BOOM! Thiamine is the Spark for Energy! According to Lonsdale it (Thiamine) is the “Spark of Life”…. http://europepmc.org/article/MED/22116701 Stress requires energy and we absolutely can NOT make energy without Thiamine. The Thiamine deficiency came First…..It is not a “Chicken AND the Egg” scenario. One interesting new study that illustrates this point and I will try and wrap up this Posterboy blog post at least for a Season of Time. Let’s go back to the B1, B2, B3 issue of picking which one is the Spark for the Autoimmune BOOM triggered by inflammation..... Sepsis is a condition in the body that is triggered by unchecked infection often….and what down regulates inflammation in the body??? Answer B-Vitamins at least in part…..we know B1, B2, and B3 work synergistically to down regulate inflammation in the body thereby controlling first inflammation and thus Sepsis. How can we know it is B1 instead of B3…because new research bears this fact out! See this Sciencedirect article about Thiamine and Sepsis and how unchecked inflammation can be a sign of a Thiamine deficiency not the other way around … https://www.sciencedirect.com/topics/nursing-and-health-professions/thiamine-deficiency quoting Effect of Sepsis on Intestinal Thiamine Uptake Thiamine deficiency is prevalent in patients with sepsis.15–17 This appears to be mediated in part via an effect of sepsis on intestinal thiamine uptake37 given recently reported observations of a significant inhibition in intestinal thiamine uptake in rat model of sepsis where the degree of inhibition was shown to correlate with the severity of sepsis. The degree of the Thiamine Deficiency correlated with the degree of the Sepsis! Again, the Thiamine deficiency came First…..It is not a “Chicken AND the Egg” scenario. To quote Ecclesiastes 3 (read it all if you get chance) it is so well known the first few verses can be quoted (or commonly known). And it is often quoted at major life events such as death and at marriages or when one gets sick…..this too can pass! But if you want energy during these emotional times you can’t pass by Thiamine! Ecclesiastes 3:1 “To everything there is a season, and a time to every purpose under the heaven:” It is time for a “Season of Thiamine” to fight off the stress and inflammation your GI tract is now experiencing because your body is low in Thiamine…… before medically diagnosable Beri Beri develops from unchecked inflammation in the body! There will be time of Joy! Of Celebration that you found out what was causing your “Chronic” Fatigue that the doctors couldn’t diagnose! Because they didn’t know the cause of the unchecked inflammation https://www.msn.com/en-us/health/other/chronic-fatigue-syndrome-may-be-due-to-an-overactive-immune-system-study-shows/ar-BBR5ba3 I had similar things happen to me….before Sepsis develops someone in a Celiac Crisis will develop Refeeding Syndrome….. presenting itself as “Electrolyte Abnormalities” See my Posterboy blog post how I was a Posterboy for a Thiamine deficiency post and the doctor’s were misdiagnosing it! If this is the right diagnosis you would expect patterns to emerge in the research and when we look we see we/they do! 2 out of 3 Celiac’s who do not respond to a gluten free diet get (feel) better when they are treated for SIBO or unchecked inflammation from an overgrowth of bacteria! And a Thiamine Deficiency is known to be common in a SIBO diagnosis. It Turns out the Bacteria need Thiamine for their Spark of Life too! Draining your in the process leading to your Fatigue! And new research is emerging that Toxic Shock (this is no longer an hypothesis) but a working Theory that “Thiamine (vitamin B1) (can be used) in septic shock: a targeted therapy” which IMO is being triggered by gluten in Celiac’s when you First get low in Thiamine presenting as a Celiac Crisis or being Misdianosed as Refeeding Syndrome or SIBO in IMO. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024754/ I must stop before this blog post gets too long again…… I truly hope it helps someone else! It is time for a Season of health! I share that it might help the next person…..so they won’t have to suffer without the doctor’s help the way I did! I hope this is helpful but it is not medical advise. 2 Corinthians 1:3, 4 3 Blessed be God, even the Father of our Lord Jesus Christ, the Father of mercies, and the God of all comfort; 4 Who comforteth us in all our tribulation, that we may be able to comfort them which are in any trouble, by the comfort wherewith we ourselves are comforted of God. 2 Tim 2:7 “Consider what I say; and the Lord give thee understanding in all things” this included. Posterboy by the grace of God, ADDENDUM IF you have a spare hour of your time this youtube link about how a Thiamine Deficiency can lead to Vagus Nerve disorders is worth your time! Entitled “Is Thiamine Deficiency Destroying Your Digestive Health? Why B1 Is ESSENTIAL For Gut Function” Or if you prefer to reading to video this is a nice article that shows the Thiamine Deficiency in a SIBO Patient connection… and remember in 2 out of 3 Celiac’s who do not get better eating a gluten free diet feel better after treating their SIBO Or is it more appropriately treating their Thiamine Deficiency??? A Season of Thiamine (or a B-complex) can tell you if it was the "Chicken or the Egg". What have you got to loose but Time! It is time for a Season of Health! https://www.eonutrition.co.uk/post/thiamine-deficiency-a-major-cause-of-sibo
  12. Celiac.com 01/31/2020 - We've written previously about the connection between SIBO and rosacea, along with efforts to develop a breath test for celiac disease. Diagnosis for small intestinal bacterial overgrowth (SIBO) is usually made using non-invasive breath tests (BTs), namely lactulose BT (LBT) and glucose BT (GBT). However, there is no consensus opinion on the best way to standardize the test parameters. In an effort to move toward a consensus opinion, a team of researchers recently set out to perform a meta-analysis to analyze diagnostic performance of LBT/GBT for SIBO diagnosis. The research team included Giuseppe Losurdo, Gioacchino Leandro, Enzo Ierardi, Francesco Perri, Michele Barone, Mariabeatrice Principi, and Alfredo Di Leo. They are variously affiliated with the Section of Gastroenterology in the Department of Emergency and Organ Transplantation at the University “Aldo Moro” in Piazza Giulio Cesare in Bari, Italy; the Gastroenterology Unit at the National Institute of Research for Gastroenterology “Saverio De Bellis," Castellana Grotte, in Bari, Italy; and with the Digestive Endoscopy Unit, National Institute of Research “Casa Sollievo della Sofferenza,” in San Giovanni Rotondo, Foggia, Italy The researchers reviewed medical literature databases for articles that focused on successful SIBO diagnosis via LBT/GBT in comparison to jejunal aspirate culture, which is the reference gold standard. The team calculated pooled sensitivity, specificity, positive, and negative likelihood ratios and diagnostic odd ratios. They then drew summary receiver operating characteristic curves, and calculated the pooled areas under each curve. They chose 14 studies in all, and found that pooled sensitivity of LBT and GBT was 42.0% and 54.5%, respectively. Pooled specificity of LBT and GBT was 70.6% and 83.2%, respectively. In patients with abdominal surgery history, pooled GBT sensitivity and specificity seemed to offer better performance, with levels of 81.7% and 78.8% compared to sensitivity of 40.6% and specificity of 84.0% for subjects with no SIBO predisposing condition. Overall, GBT seems to work better than LBT. A cut-off of delta H2 expired other than and lower than 20 ppm shows a slightly better result than above 20 ppm. From these data, the team concludes that great tests are the most effective way to assess patients with surgical reconstructions of gastrointestinal tract. Read more in the Journal of Neurogastroenterol Motil. 2020 Jan; 26(1): 16–28
  13. Hello, and thank you for your interest. I've never seemed to really have the time for forums, but I'm giving it a try for two reasons: first, perhaps someday it will inform someone asymptomatic considering going gluten-free that, maybe, there could be risks, and second, because I have no idea what's going on anymore, haven't found any similar cases online, and am hoping for some advice from people with greater experience. The following is a product of my memory and a number of notes I took regarding my symptoms once things started getting bad. Henceforth, I shall reserve the term ‘pain’ to refer to ‘sharp pain’, which I define as discomfort that appears to affect my breathing (i.e. gasping, holding, unsteady, etc.). I shall use the term ‘ache’ to refer to ‘dull pain’, which I define as discomfort that does not encourage any changes to my breathing (excluding the expression of discomfort, i.e., moans, cries, expletives, etc.). I will put numbers [#] or intervals [#-#’] following a symptom to provide a measure for the intensity of discomfort out of 10 caused by the symptom. I apologize in advance for the length; it is a long story, so hearken here and gather 'round all ye ready for a tale… ------------------------------------------------------- First, some basic personal info: I'm a 29-year-old, ~165 lbs. male in grad school with no marks of malnutrition I know of (strong teeth, healthy weight, intelligent, etc.), and (before all this started at least) no known allergies or autoimmune problems of any kind (though my father has psoriasis). I have never shown signs of hypochondria, and, if I’m honest, have usually required prodding to consider going to the emergency room (ER) or doctor. Recently, I have started to suspect in hindsight that I may have had some mild, lifelong constipation. Finally, I was diagnosed with obsessive compulsive disorder (OCD) when I was 12 and have taken fluoxetine (SSRI, anti-depressant) since, though have still dealt with compulsions daily. It is a constant struggle, for which I’ve done behavioral therapy, and engage in at least 30 minutes of mindfulness meditation daily as well. While attending college I was diagnosed with adult ADHD and prescribed Vyvanse, which I’ve taken daily for ~8 years now. Roughly 4 years ago (Summer 2015) a relative of mine was diagnosed with Celiac Disease (celiac disease). While I had no symptoms (asymptomatic), I got a blood test and was found to be borderline, so my doctor suggested that I start a gluten-free (gluten-free) diet. While not terribly pleased by losing glutenous foods, the neurological connections to celiac disease made me think my OCD might improve. After all, even if it didn’t seem to help, everything I read seemed to suggest I could always just go back to eating gluten again. Thus, in January 2016 I switched to a diet of mostly potato patties, fruit, and celery in the morning and a mix of rice, beans, broccoli, cheese, and a little chopped meat for lunch and dinner. I initially lost a little weight (5-10 lbs), but returned to my normal weight within a few months once I got the hang of it. I was a little depressed at first by the loss of glutenous food, but tried to remain positive. However, after a while gluten-free, I noticed a very mild but slowly worsening gut ache [1-3]. Further, while I had been drinking milk religiously my entire life, I found it now made my stomach ache [2-3] after going gluten-free (it is noteworthy that I did not appear to have a similar issue with cheese, suggesting Casein's the problem?). Being extremely stubborn and feeling gluten had already restricted my diet enough, I refused to give up milk for another 3 months, but finally gave in as the discomfort worsened [3-4]. I also began noticing the development of other disconcerting issues, including mild fatigue [2] and a painful red rash [4] on my neck that appeared when stressed (mostly in cases of lack of sleep). Worried by these developments, I looked up more info online and found out how I really should have gotten an endoscopy+biopsy before going gluten-free. I asked my doctor, got directed to a gastrointestinal (GI) specialist, scheduled an endoscopy for ~3 months down the road (March 2017), and started eating gluten again. This is where things start getting weird: I found that upon eating gluten again, the gut ache vanished, and I could drink milk again. I had already gotten hints of this impression from a couple instances of likely gluten contamination, but this seemed to confirm it. While the endoscopy report suggested nothing looked amiss visually, the biopsy showed some villus atrophy suggestive of (among admittedly a few other things) celiac disease, and my GI doctor made the diagnosis of celiac disease (Summer 2017). Still concerned with the constant, worsening gut ache and the discomfort from drinking milk (both of which returned upon resuming a gluten-free diet), I continued to see the GI specialist, who scheduled a Lactose breath test. This came back negative. By the time I saw my GI specialist again it had been another 6 months gluten-free (scheduling both appointments and testing involve ~2.5-3 month wait times), and by then the ache had returned and worsened [3-6]. He recommended a hydrogen breath test, but due to an internal error, this didn't get scheduled correctly. I did not make too much of a fuss, since, if I'm completely honest, I had not been much impressed by the usefulness of the Lactose test, and all these tests were getting expensive for a grad student. Moreover, by the time I found out, the ache had grown severe enough that I had started intentionally eating gluten periodically, as it appeared to sort of 'reset' the growing gut ache, and was finding it a workable, if temporary, solution (~March to June 2018). In general, I also remember (throughout but especially around this time) not being able to shake the feeling that I was somehow hurting myself with the gluten-free diet, but suspicious of my desire for glutenous food and with the same encouragement from others, I ignored the feeling. Now, starting in May 2018 I had also started taking an herbal supplement encouraging good circulation for an unrelated, lifelong health issue. While this originally seemed fine, beginning around July 4th I started to feel dizzy [2], sweaty [1], and having pain in my chest (heart) [0-5], lower-left abdomen [0-5], upper-left abdomen [0-2], and a vertical pressure [2-5] slighly left of the middle of my abdomen (right where my aorta should be). This came to a head July 7th, when one night it got so bad [7-8] that I couldn't sleep, kept hyperventilating (which I repeatedly calmed using breathing techniques learned in behavioral therapy), and felt 2 'tearing' pains [4] in quick succession in my chest (just left of sternum, near 4th rib) followed by an immediate decrease of the (aorta?) pressure I’d been feeling. Finally realizing the supplement might be behind it, I stopped taking it the next day. Most of the symptoms subsequently went away, save for an ache in my chest [2-4], pain in my lower-left abdomen [2-3], pain in my upper-left abdomen [0-2], a lump in my lower throat [2-3], and a general ‘hollow’ feeling in my left side, all of which have remained (with varying intensity) up to the present. Since my grandfather had total heart failure at 36 and, after several instances, later died due to a genetic predisposition for a prolapsed mitral valve, I was concerned when the chest (heart) discomfort failed to go away after several days. Convinced by my friends that I probably should have gone to the ER that night, I went and got a chest x-ray, abdominal aorta ultrasound, and electro-cardiogram, none of which showed signs of trouble (July 2018). Later (January 2019), while trying to get to the bottom of all the pain I was in, I would also see a cardiologist who did an exercise stress test, a 24-hour holter monitor test, and an echo-cardiogram, none of which suggested anything untoward, and leads me to suspect my heart itself is okay despite the chronic discomfort. Now, back to the matter at hand: after that night of cardiac distress, the next time I tried to eat gluten I had severe nausea [6-7] and vomited. A month later (August 2018) I tried to eat gluten again, and had terrible pain in my upper-left abdomen [7-8] and an intense, painful, bloating sensation just below where my ribcage meets [6]. I later did some research online and found discussions of celiac disease being 'activated' by a stressful physical event, and suspected this might explain my sudden development of symptoms. That said, I found nothing regarding cases of asymptomatic celiac disease becoming symptomatic, and nothing about going gluten-free causing bacterial overgrowth (which was my leading theory on the growing gut ache), though I did find it commonly develops in patients with celiac disease. In any case, deprived of gluten, I lost the defense I'd been using against the growing gut ache. Eventually the ache became debilitating [5-6], and was accompanied by significant gas (~30-40 instances of flatus daily), increased burping, discomfort for around ~2 hours after eating [2-6], worsening of the lump in my throat [0-5], increased bowel movement urgency, occasional mucus in stool, irregularity in bowel movements, and intense fatigue [4-6]. Fortunately, this peak in symptoms occurred right around my next GI appointment (October 2018), where, considering the apparent severity and symptoms, the doctor decided to prescribe antibiotics for Small Intestinal Bacterial Overgrowth (SIBO) despite not having results from a breath test. Shortly after taking the antibiotic, I began to feel much, much better; the growing gut ache and gas largely disappeared, though notably the off-and-on pain in my lower- and upper-left abdomen and the ache in my chest (heart) remained. The lump in my lower throat also returned off and on [0-2], as did the gut ache gradually over time, which now generally included a sore tenderness throughout my belly [1-2]. Free of the crippling gut ache, I turned my efforts to sorting out the remaining fatigue and discomfort. I got a thyroid panel (November 2018), where I had mildly high levels of TSH (~6.4 to 7.4) in 2 consecutive thyroid blood tests six weeks apart (which could explain the lump in my throat), though thyroid antibodies returned negative and T3 & T4 levels remained normal. Hoping to avoid a recurrence of SIBO, I also tried several shifts towards a low FODMAP diet consisting mostly of salad, sweet potatoes, plain white chicken, fish, and a big mug of bone broth (with quality gelatin added in for good measure) every day (by this time, I had switched to 2 meals a day to minimize time spent incapacitated after eating). Nevertheless, by February 2019 the SIBO was back [5-6], and I had to request another round of antibiotics, which left my gut feeling even sorer than the last time. The continuing fatigue [4] left me tired all the time, and the lump in my throat began to be accompanied by an occasional ache extending down into my upper torso slightly [4]. Over a month after stopping the 2nd round of antibiotics (April 2019) I was finally able to get the Hydrogen breath test, and while I felt a rise in discomfort after drinking the glucose [from 2 up to 5], the test came back negative. However, my GI doctor suggested the tests aren't all that reliable and the effectiveness of the antibiotics is strong evidence. In this time (around January 2019 and on), I should also mention the chest (heart) ache had begun to mildly spread into my left shoulder [1-2], arm [0-1], and leg [1-2], as well as up the left side of my neck and head [0-1] (though to be clear, these are more worrying than intense, and other than my neck and head they seem closer to muscular aches). Perhaps related to the former, during a visit home my family pointed out that the way I walk has changed: my left heel turns inward, enough that it has warped the shape of my shoes over time. Over the winter (Jan.-April 2019), I also noticed my left leg seemed to get colder faster than my right, and whenever I exercise the muscles of both my left leg and left arm appear to tire faster. I occasionally have mild headaches [1-3] in the left side of my head, which while I found initially disconcerting, is evidently not terribly uncommon in people. Meanwhile, having been monitoring my TSH (which was up to ~9.4 by March 2019, but still negative on thyroid anti-bodies), I was prescribed a low-dose (25 mcg) of Levo-Thyroxine for the Hypothyroidism I was mysteriously developing. Unfortunately, I found the new medicine not only made my stomach hurt [3-4], but also didn't much alleviate the fatigue or lump in my throat, and appeared to make the chest (heart) discomfort worse [3-5]. Fearing Hashimoto's or other autoimmune disease commonly paired with celiac disease, I got a thyroid ultrasound (March 2018), but it returned unremarkable. My next doctor visit 6 weeks later showed a TSH of 8.9, so my doctor increased the Levo-Thyroxine dosage (50 mcg), though could offer no comment regarding the chest (heart) discomfort it seemed to exacerbate. Before I started taking the increased dosage however, my GI doctor suggested I hold off on taking anymore Levo-Thyroxine to see where I stand in TSH without the medicine, which I've done for ~6 weeks now and will be getting checked again soon. That largely brings us to the present, save for one last development. A few weeks ago (May 2019), I caught a stomach bug from my roommate. While mildly unpleasant for him, it was the first time I'd gotten sick with anything significant since this all started, and it felt more intense than any sickness I can recall [8-9]. Enough so that when I felt the rise in nausea that usually precedes vomiting, it was so intense I briefly blacked out and fell into the wall (something I've never experienced before). After coming to, I suddenly became drenched in sweat over a dozen seconds or so, despite lacking any noticeable fever and sitting still. Having trouble thinking clearly and worried by the fainting, I entrusted myself to my roommate, who took me to the ER where they explained I had an incidence of 'Vagus syncope' due to my Vagus nerve being overstimulated. My particularly intense reaction to what seemed a common 24-hour stomach bug has lead me to wonder if perhaps the nerves of my gut may just have somehow become hyper-sensitive causing constant “functional pain”, which could explain why so many tests have returned negative. Then again, it could also just be the bug was particularly hard on my gut because it is already inflamed. Naturally, neither can be considered more than just speculation on my part, but I wish to make it clear this instance of sickness was very far from ordinary as far as my life experience is concerned. That largely does it as far as history goes. My diet has relaxed to a fusion between my former gluten-free rice-based diet and the low-FODMAP (also gluten-free) diet. I regularly take Berberine, which has appeared to help keep the SIBO from recurring for at least the last 4 months. I still experience mild to severe gut discomfort after eating for around 2 hours [2-6], and thus stick to 2 meals a day. ‘Small’ (a relative term) quantities of gluten (1 cheez-it/day over 1 week in May 2019) no longer appear to cause a noticeable reaction, though I have not repeated this or any other tests involving gluten over the last several months in fear of aggravating my gut. Moreover, with the constant (but inconsistent) gut symptoms I have, I’m not sure I can confidently identify a reaction anyways. I still have trouble with milk [0-4], but try to eat at least some dairy regularly to avoid losing the ability to. The most consistent source of discomfort in the last few months is in my lower-left abdomen [2-6], followed by the upper-left abdomen [0-6] and chest (heart) [1-6], the 3 of which appear to be connected somehow. When particularly intense [>4], these sources of discomfort will also extend into my back, and in the case of the chest (heart) ache I can sort of feel where the two tearing sensations occured. On rare occasion the upper-left pain will be mirrored to my right side, though with lower intensity [0-4]. My left leg and arm still tire faster and still constantly ache a little [0-2], but beyond being disconcerting this usually remains only a very minor annoyance. I'm still terribly tired [3-6], and the lump in my throat comes and goes [0-4]. Mornings continue to be when symptoms tend to be at their worst. ----------------------------------------------------- That should do it; if you’re still reading this, I both respect and appreciate your determination and perseverance. If I didn’t sound all that worried throughout all this, know that it is entirely an affectation; I’m pretty much terrified at this point. I’m always tired, I’m losing my handle on my OCD, my daily meditations are in shambles, and I am constantly falling behind with my work with all the time lost incapacitated after eating (enough now that I suspect I’ll need to put off graduating). Even more though, the gradual changes in my personal behavior and outlook on life deeply frighten me. Obviously, it makes no sense (scientifically, as far as I understand it) that my problem was/is being gluten-free, and indeed, I could easily believe I shouldn’t eat gluten despite its former effectiveness at easing the growing gut ache. More, I suspect my original change in diet somehow messed up my gut biome, and my ‘glutenings’ were re-establishing whatever was going on before. My positive response to antibiotics seems to demand my problem at least involves something to do with gut flora. The hypothyroidism remains a complete mystery to me, seeing as the antibodies are negative. The hollow feeling and localized pains in my left side make me think part of the problem likely involves certain organs, though how they could have been damaged after that night of apparent cardiac distress remains unknown to me. Having done more research I’m really thinking the lower left pain has to do with my sigmoid colon (I can kind of feel it when I flex for a bowel movement). My best guess would be some sort of diverticular disease, as it fits best with my other symptoms (mucus in stool, recurring SIBO, discomfort after eating, etc.). Since it hasn’t gotten better after nearly a year I think a CT scan would be justified, but my doctors seem resistant. 29 is pretty young for diverticula, but my thought is that the mild chronic constipation I’ve always had might have hastened the process. It would also be nice to just have a picture at this point to rule out things like mesenteric ischemia. I don’t mean to complain as I clearly don’t have it as bad as some stories I’ve read, but I’m getting a little desperate for help and don’t seem to be getting anywhere with what I’ve tried so far. I’ve scheduled an appointment with a new doctor, though my current doctors are taking a lot of time to share my records. I’ve also scheduled some counseling in hopes of helping to rule out psychosomatic effects and better monitor my psyche (I’ve never really had much success with counseling in the past but I’m willing to try again at this point). Regardless, please let me know if you have any suggestions, ideas, references to similar cases you’ve heard, or anything else you think might be useful; I’d truly appreciate it.
  14. Good evening everyone, thanks for reading this post. A bit of background about me... I’ve had problems for around 20 years, but everything got really bad around the time I got pregnant 8 years ago. I started getting things like bloating, my small intestines move my tummy up and down, excessive wind, abdominal pain, migraines up to 5 days a week, balance problems, feeling/being sick, depressive, anxiety, acne, itchy blister like rash on feet, hands and face, heartburn, joint paint in hips and back so bad I often can’t stand up for long or can’t stand up straight. I have tingles in my hands and feet and legs. I have a shooting nerve pain from my head/neck down my arm. Heart goes fast & heart palpitations, I can swell up. Struggle breathing. Constipation and diarrhoea. Mucus in stools. Tinnitus. Stomach aches. Brain fog. Tired. The list goes on. Last year I couldn’t take anymore and as I was fed up with feeling so sick all the time. The NHS told me I was lactose intolerant, but I never felt better, so I paid to see a Dietitian, who is incredible. She told me to give up dairy and soya and I instantly started feeling better. She said I had an dairy and soya allergy. Fast forward 10 months and I still had the underlying problems with wind, bad abdominal pain, bloating, acne, blistery itchy rashes, (my face was completely out of control with this strange red/blistery rash) migraines just ones a week (I feel I am blessed in comparison to what I was), heartburn, stomach aches, stomach moves up and down, balance problems, tingles in my hands and feet, stabbing nerve pain from neck to arm, tinnitus, joint problems, mucus, depression, heart palpitations, sleep problems, feeling too hot or too cold. I have recently been told I have SIBO (small intestine bacteria overgrowth). I have been on the low FODMAP fruit and veg diet, which did nothing. By pure accident I took out wheat from my diet and suddenly realised I was feeling better, so my dietitian told me to go gluten free, which I did for 5 weeks. My skin had never been so clear. My face looked different. Stomach stopped bloating, wind improved, the inflammation from my back ache/hip joints improved, but the hip pain is still there, depression lifted, heart palpitations gone, felt so energetic and happy, heart burn and balance problems gone. I then decided to go back on wheat as I want to get tested for celiac, which I am on the waiting list for. I am in the UK, so it could be a very long wait. I have now been gradually reintroducing it for 3 weeks. Going back on gluten, everything has come back, except my wind and abdominal pain isn’t as severe (not everyday anyway, but maybe every other day). My balance seems better. But everything else is there, acne, itchy rash, terrible joint pain (I have just had an X-ray to test for osteoporosis and am having bloods to test vitamin levels and for arthritis), mucus in stools, sometimes they float, I have this weird thing where I can see my small and feel intestines moving about. I have videos of my stomach doing the Mexican wave, it’s like I am pregnant. I’m irritable and depressed, heart palpitations back, feel tired, heart burn back, urgency for toilet back, tingling in hands and feet never disappeared. Because my stomach doesn’t seem quite so severe, I started wondering if my dairy and soya allergy may have disappeared. I’ve had a tiny bit of Clover butter and been ok. Now I can’t decide whether to try other things. I am also being tested for inflammatory bowel disease as I had blood in my stools at times along with the mucus. I think that will be negative though. I’ve had 20 years of feeling rubbish, eliminating this that and the other during the course. Could 5 weeks of gluten free have cured my SIBO, dairy and soya allergy and gluten problem? I want to know what experiences you had if you accident had gluten or tried reintroducing it. Was it a slow downhill process or instant and what were your symptoms? Was it all GI or other symptoms? I read that everyone is different, but I’d rather hear from real people. I don’t want to obviously have an endoscopy/bloods if I don’t need to, but I also don’t want to continue not knowing. My brother has similar problems and I have also watched my mum have problems over the years (although she wouldn’t say anything). My little girl who has just turned 5 always makes me think as she’s always got such a pot belly. She’s tiny, always been very skinny, with a pot belly. She has soooo much wind all the time. She always needs the loo, but often it’s wind and her stools can be quite explosive. Thank you in advance for reading this, I really appreciate any advice.
  15. This small study suggests that taking probiotics may contribute to brain fogginess and bloating. While it may be good to keep the large intestine (colon) populated with healthy bacteria, taking probiotics in patients with impaired gastrointestinal mobility (e.g. diabetes, celiac disease) may contribute to issues like SIBO where the bacteria may populate in the small intestine instead. https://medicalxpress.com/news/2018-08-probiotic-link-brain-fogginess-severe.html Talk to your doctor about taking a probiotic. Consider modifying your diet to include foods that can help populate the large intestine (e.g. fermented foods), instead of taking a supplement.
  16. have Hashimotos hypothyroidism. was whole foods vegan for 5 years. in January I went to get blood panel ( because I couldnt digest properly and was having depression come back and weakness) and ldl was high and omegas low, decided to start eating meat again. for the last 6 months I've been struggling with hemorrhoids and possibly anal fissures. went gluten free once again (prior to all of this I had started eating gluten again for about 3 months) and mostly AIP and hemorrhoid has improved but not gone and still bleeds. if I eat certain things my stomach from below my belly button feels swollen, I thought possibly sibo but last weekend I ate pizza (not gluten free) and ever since then my stomach has felt super swollen . is this possibly just a gluten issue? It's not gas but literally feels like my intestines are swollen, and it lasts for days after eating gluten or other foods that I suspect had gluten contamination. The swelling typically only happens the next day or several hours later that night and lasts 3-5 days.
  17. So I posted back in early February2017 about having some extreme brain fog, light headed, vision problems amongst other symptoms. I thought it was because I had started a strict gluten-free diet again (after eating carelessly for a couple months and being a celiac) and was possibly have gluten withdrawals or even cross contamination some how in my diet. I literally went to 3 different MD’s and even my Optometrist. And they all told me I needed to eat more and get better “quality” sleep. After a year of strict sleeping/eating schedules the symptoms never went away and it felt like this constant drunk state of going about my day. Finally I switched to a Holistic Doctor (I think that’s what type of Doctor he is). Anyways after the first appointment he pretty much knew what I had and sent my home with two take home tests. One for SIBO, the other for Adrenal Fatigue. I tested positive for both with extremely solid results. I always told myself I’d come back on this forum to share my info if I ever figured out what was wrong with me because no one seemed to know exactly what was going on and looked at me like I was some crazy lady making up stuff. I am one week on the Rx. and already feel so much better. My ability to communicate and focus in conversations is much better. I literally felt buzzed when talking before and it took way too much effort to really even stay on topic with people. And even if I did stay on topic I couldn’t remember hardly what was discussed. As of right now my vision is still slightly off, even though my optometrist said I have perfect vision. It’s more so like the room has a hard time catching up with itself when I redirect my focus. But my energy is up and I can only assume my results will keep getting better with each passing day. I hope this helps someone who’s trying to figure out what’s going on with themselves.
  18. Hello, I'm looking for a Gastro Psychiatrist or GI doctor who works with mental illness and would appreciate any recommendations. I've also thought about looking for immunologist who work with the gut microbiome. I live in Nebraska so a doctor in the Midwest would be ideal, but I would appreciate any recomendations! I struggle with anxiety, depression, and multiple food allergies. I've been gluten free about 6 months so I don't think I can be tested for celiac. I've been thinking about doing a gluten challenge to be tested, but out of all my food allergies gluten seems to make anxiety the worst. So, I'm not sure if its worth testing or just keep avoiding. While I've seen improvement in digestive and mental health symptoms since eliminating food allergies, I'm still struggling. I highly suspect I have immune related issues from dysbiosis as I was regularly put on antibiotics for sinus infections growing up. I have a lot of symptoms that point to Candida, histamine intolerance, or SIBO. It would be great to investigate some of these causes under the care of a physician. Any advice is appreciated! <3 Elizabeth
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