• Ads by Google:
     




    Get email alerts Celiac.com E-Newsletter

    Ads by Google:



       Get email alertsCeliac.com E-Newsletter

  • Announcements

    • admin

      Frequently Asked Questions About Celiac Disease   09/30/2015

      This Celiac.com FAQ on celiac disease will guide you to all of the basic information you will need to know about the disease, its diagnosis, testing methods, a gluten-free diet, etc.   Subscribe to FREE Celiac.com email alerts   What are the major symptoms of celiac disease? Celiac Disease Symptoms What testing is available for celiac disease? - list blood tests, endo with biopsy, genetic test and enterolab (not diagnostic) Celiac Disease Screening Interpretation of Celiac Disease Blood Test Results Can I be tested even though I am eating gluten free? How long must gluten be taken for the serological tests to be meaningful? The Gluten-Free Diet 101 - A Beginner's Guide to Going Gluten-Free Is celiac inherited? Should my children be tested? Ten Facts About Celiac Disease Genetic Testing Is there a link between celiac and other autoimmune diseases? Celiac Disease Research: Associated Diseases and Disorders Is there a list of gluten foods to avoid? Unsafe Gluten-Free Food List (Unsafe Ingredients) Is there a list of gluten free foods? Safe Gluten-Free Food List (Safe Ingredients) Gluten-Free Alcoholic Beverages Distilled Spirits (Grain Alcohols) and Vinegar: Are they Gluten-Free? Where does gluten hide? Additional Things to Beware of to Maintain a 100% Gluten-Free Diet What if my doctor won't listen to me? An Open Letter to Skeptical Health Care Practitioners Gluten-Free recipes: Gluten-Free Recipes Where can I buy gluten-free stuff? Support this site by shopping at The Celiac.com Store.

New To Celiac. Test Results--Celiac Or Gluten Sensitivity?
0

13 posts in this topic

My 5 year old daughter had lab work done because of her weight. She has not gained anything in over 2 years and is sitting steady at 32 pounds, she will be 6 in July. Her lab work came back yesterday with the result of possible Celiac Disease and her PCM has referred her to a Gastroenterologist...just waiting for the referral to go through. I am completely clueless about all of this, nothing like this crossed my mind...I actually figured it would be a thyroid issue. I went through her symptoms the last few years and this is what I have...

 

Decreased appetite

Diarrhea (not constant but at least once or twice a week)

Easily bruises

Very poor weight gain

Fatigue

Mouth Sores

 

Since I am so new to any of this, I have tried really hard to look through all the lab results here and try to decipher my daughters. I have spent the whole afternoon reading this site. 

 

Here are the labs

 

IgA 143 (Normal) Limits 33-185 mg/dL

Endomysial Screen (Negative)

tTG Ab, IgA 2.0 Range <20 Negative, 20-25 Equivocal, >25 Positive

 

Gliadin Peptide Ab, IgG 22.6 (Abnormal) Range <20 Negative, 20-25 Equivocal, >25 Positive

Gliadin Peptide Ab, IgA 4.1 (Normal) Range <20 Negative, 20-25 Equivocal, >25 Positive

 

tTG Ab, IgG 17.4 (Normal) Range <20 Negative, 20-25 Equivocal, >25 Positive

 

Thanks in advance to anyone who can offer me some input! 

 

 

0

Share this post


Link to post
Share on other sites
Ads by Google:
Ads by Google:


Welcome to the board, decemberhill,  :) and I am sorry it looks like your post has been missed and overlooked :(   Let me attempt to rectify.

 

Your daughter's blood test results show that she makes normal quantity of IgA antibodies, and therefore the IgA testing should be valid for her.

 

The most specific test, endomysial antibodies (EMA) is not positive and her tTG Ab IgA is also negative, as is her Gliadin Peptide Ab IgA (DGP IgA).  However, her Gliadin Peptide Ab IgG (also known as DGP IgG)  is positive.  IgA and IgG are both autoimmune antibodies.  The IgA is usually used and considered to be the celiac antibody; but if an individual does not make normal total quantities of IgA they use the IgG tests.

 

There has recently been some discussion on the board about the meaning of IgG positives on the DGP, and what it means if the person being tested is a normal IgA producer.  Nobody so far has been able to state that it means anything other than celiac disease.  This is probably the reason for the GI referral, so that he can do an endoscopy with biopsy to check for celiac damage in the small intestine.  Do not let him say it is not necessary.  Insist on having it done, and that he take at least 6 samples, because the DGP is the most sensitive of the tests and tends to catch early celiac disease, before there is too much damage.  And if there is not too much damage the naked eye is unable to see it and we have to rely on the biopsy samples and the microscope :)

0

Share this post


Link to post
Share on other sites

Decemberhill,

 

The only test I came back positive on was the DGP igG.  I am currently waiting for my biopsy results to come back in a few weeks.  I see that your daughter bruises easily, as I do too.  I thought it was something to do with my iron, but it turned out my iron and ferritin levels were fine.  I'm deficient in Vitamin K, which also causes bruising  :wacko:

 

here are two links to threads I have started:

http://www.celiac.com/gluten-free/topic/99439-need-help-with-tests-results-please/

http://www.celiac.com/gluten-free/topic/100245-other-known-causes-of-high-dgp-igg-besides-celiac/

 

hope these give you some other ideas!

0

Share this post


Link to post
Share on other sites

Thank you so much for your responses. The other diagnosis they are throwing around is Cystic Fibrosis and we go in to talk about that on Thursday. I would much rather it be a Gluten issue. 

 

From my reading and I hope I am correct...the test she was positive with, the DGP IgG shows that there is tissue damage relating to gluten? Also, on two of the tests testing IgA are low...does that mean anything or is that a good thing? Our referral for GI has been approved, although the Dr she was referred to does not treat children so I had to find her a pediatric GI which I think works much better. The Ped Dr has a special interest in Celiac. 

 

PowerOfPositive...please let me know how your biopsies turn out. Looking at so many labs and trying to decipher, I remember seeing your post about only being positive with the DGP IgG. I have started a food diary for my daughter as well as documenting her poo everyday. Is there anything else I should document or note? The GI said that new patient appts are already booked into June...so I think it's going to be a long time before we can get in...unless we get lucky and get a cancellation! 

 

Again, thank y'all so much. This board has been really helpful!

0

Share this post


Link to post
Share on other sites

Normally, the IgA testing is considered to be best for those who are IgA sufficient.  The DGP is a newer test than the tTG, is more specific for celiac disease, and tends to pick it up earlier than the tTG.    The low IgA results just show that those tests were negative.  So long as she makes sufficient overall IgA, the low scores on IgA testing have no special significance.  You do not have to be positive on all tests to be celiac - why having the entire panel is recommended.

0

Share this post


Link to post
Share on other sites
Ads by Google:


Thank you so much for your responses. The other diagnosis they are throwing around is Cystic Fibrosis and we go in to talk about that on Thursday. I would much rather it be a Gluten issue. 

 

From my reading and I hope I am correct...the test she was positive with, the DGP IgG shows that there is tissue damage relating to gluten? Also, on two of the tests testing IgA are low...does that mean anything or is that a good thing? Our referral for GI has been approved, although the Dr she was referred to does not treat children so I had to find her a pediatric GI which I think works much better. The Ped Dr has a special interest in Celiac. 

 

PowerOfPositive...please let me know how your biopsies turn out. Looking at so many labs and trying to decipher, I remember seeing your post about only being positive with the DGP IgG. I have started a food diary for my daughter as well as documenting her poo everyday. Is there anything else I should document or note? The GI said that new patient appts are already booked into June...so I think it's going to be a long time before we can get in...unless we get lucky and get a cancellation! 

 

Again, thank y'all so much. This board has been really helpful!

 

 

 

 

I will let you know how my biopsies turn out!  I definitely think keeping a food and poop diary would be great.  I even talked about my bowel movements to the GI with the bristol stool chart in mind.  Check it out if you haven't!  I would also suggest keeping track of water.  During my first GI appointment when I said I was frequently bloated and constipated, he asked the obligatory questions of how much fiber and water are in my diet.  I was able to tell him I usually drink between 60-80 oz. of pure water a day in addition to the fruits and veggies I eat.  Documenting any rashes of anything with pictures would also be very helpful.  According to Dr. Rodney Ford, DGP is suggestive of gluten gut damage http://drrodneyford.com/faq/bloods-tests/gluten-blood-tests.html  I am iga sufficient, but my IGA scores were both low.  I'm a 27 y/o female, but since your daughter is 5, Dr. Ford says that ttG is not as reliable in children.  

 

When the GI was going over reasons for Vitamin K deficiency, he mentioned cystic fibrosis, but people tend to be diagnosed as children so that was not applicable to me.  Are you able to get vitamin and mineral testing for children?  can anyone please help me out with this question?  Based on what you said, I would definitely make sure she is tested for Vitamin K.  If you can get your GP to do this, that will give you more information for your GI appointment.   I asked my OB/GYN if she would be willing to order vitamin/mineral testing for me, which thankfully she did without a problem.  When I had my second appointment with the GI, I said my OB/GYN sent you results from some more testing.  He said that Vitamin D deficiency was common, but I peaked his interest when I said I was Vitamin K deficient.  He said he normally doesn't see patients with that deficiency, and according to University of Maryland, a GI doctor is the type of doctor I would expect to see this deficiency since a lot causes seem to be malabsorption issues.  http://www.umm.edu/altmed/articles/vitamin-k-000343.htm  I haven't used antibiotics since last April, I don't have a blocked bile duct, no serious burns, so it seems that it's due to some kind of malabsorption for me.  I will be taking 5 mg of Vitamin K a day and 2000 iu of Vitamin D as directed by my OB/GYN and GI.  

 

I would suggest calling the GI to see if you can get in on a cancellation.  Repeated phone calls are not a bad thing  :)   I hope she starts feeling better soon!!

0

Share this post


Link to post
Share on other sites




I will let you know how my biopsies turn out!  I definitely think keeping a food and poop diary would be great.  I even talked about my bowel movements to the GI with the bristol stool chart in mind.  Check it out if you haven't!  I would also suggest keeping track of water.  During my first GI appointment when I said I was frequently bloated and constipated, he asked the obligatory questions of how much fiber and water are in my diet.  I was able to tell him I usually drink between 60-80 oz. of pure water a day in addition to the fruits and veggies I eat.  Documenting any rashes of anything with pictures would also be very helpful.  According to Dr. Rodney Ford, DGP is suggestive of gluten gut damage http://drrodneyford.com/faq/bloods-tests/gluten-blood-tests.html  I am iga sufficient, but my IGA scores were both low.  I'm a 27 y/o female, but since your daughter is 5, Dr. Ford says that ttG is not as reliable in children.  

 

When the GI was going over reasons for Vitamin K deficiency, he mentioned cystic fibrosis, but people tend to be diagnosed as children so that was not applicable to me.  Are you able to get vitamin and mineral testing for children?  can anyone please help me out with this question?  Based on what you said, I would definitely make sure she is tested for Vitamin K.  If you can get your GP to do this, that will give you more information for your GI appointment.   I asked my OB/GYN if she would be willing to order vitamin/mineral testing for me, which thankfully she did without a problem.  When I had my second appointment with the GI, I said my OB/GYN sent you results from some more testing.  He said that Vitamin D deficiency was common, but I peaked his interest when I said I was Vitamin K deficient.  He said he normally doesn't see patients with that deficiency, and according to University of Maryland, a GI doctor is the type of doctor I would expect to see this deficiency since a lot causes seem to be malabsorption issues.  http://www.umm.edu/altmed/articles/vitamin-k-000343.htm  I haven't used antibiotics since last April, I don't have a blocked bile duct, no serious burns, so it seems that it's due to some kind of malabsorption for me.  I will be taking 5 mg of Vitamin K a day and 2000 iu of Vitamin D as directed by my OB/GYN and GI.  

 

I would suggest calling the GI to see if you can get in on a cancellation.  Repeated phone calls are not a bad thing  :)   I hope she starts feeling better soon!!

It's entirely possible to be diagnosed with Cystic Fibrosis and Celiacs. I myself have both, I was diagnosed with CF at 6 months old but struggled until I was 26 with a lot of numerous health issues. I think having CF made my docs write off the possibility of Celiacs also being an issue but the vitamin deficiencies are the same and a lot of the symptoms are the same. Many people have been diagnosed as adults with CF, the oldest person ever diagnosed was in her sixties and her only symptoms up until then were chronic sinus infections and a few bouts of pnuemonia. Get tested for both.

0

Share this post


Link to post
Share on other sites

An osteopathic functional medicine doctor I had my 9 year old son too was offering nutrient absorption tests for him.  Yes, children may get them.  Some chiropractors can order them.  In the end my son didn't have them.  I had nutrient tests and they were very helpful for me.

 

Diana

0

Share this post


Link to post
Share on other sites

While we are still in the testing mode for my 2yr old...just wanted to confirm that nutrient testing is also done at the young age.

She's had a baseline and a followup already since she was 18months old.

 

(granted no closer to a dx, but we are watching nutrient levels)

0

Share this post


Link to post
Share on other sites




While we are still in the testing mode for my 2yr old...just wanted to confirm that nutrient testing is also done at the young age.

She's had a baseline and a followup already since she was 18months old.

 

(granted no closer to a dx, but we are watching nutrient levels)

Not sure what exactly you mean? A doctor can test blood to see if the iron, vit D, B12, etc is at a good level or not. I would be careful about some of these " tests" by "doctors" that are not MDs. Many have no real science behind them and are designed to extract your money as insurance won't cover them.

0

Share this post


Link to post
Share on other sites

Sorry, my post was in response to the question here:

When the GI was going over reasons for Vitamin K deficiency, he mentioned cystic fibrosis, but people tend to be diagnosed as children so that was not applicable to me.  Are you able to get vitamin and mineral testing for children?  can anyone please help me out with this question?  Based on what you said, I would definitely make sure she is tested for Vitamin K.  If you can get your GP to do this, that will give you more information for your GI appointment. 

Yes, any MD is able to the testing, as we are seeing only MDs for my daughter's dx quest.

 

I'm sorry if I confused anyone if I misread the question.

0

Share this post


Link to post
Share on other sites

Sorry, my post was in response to the question here:

Yes, any MD is able to the testing, as we are seeing only MDs for my daughter's dx quest.

I'm sorry if I confused anyone if I misread the question.

Great! Lots of stuff posted in between! :)

I see no reason her pediatrician couldn't test her blood for vitamins, etc.

I found this but it seems a bit extreme if you haven't had blood levels done first. Maybe something down the road if things don't improve?

http://www.nlm.nih.gov/medlineplus/ency/article/003606.htm

0

Share this post


Link to post
Share on other sites

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!


Register a new account

Sign in

Already have an account? Sign in here.


Sign In Now
0

  • Forum Statistics

    • Total Topics
      107,341
    • Total Posts
      935,591
  • Member Statistics

    • Total Members
      65,004
    • Most Online
      3,093

    Newest Member
    susa
    Joined
  • Popular Now

  • Topics

  • Posts

    •     http://www.takepart.com/article/2014/08/11/coffee-adulterated https://www.thetimes.co.uk/article/how-was-your-morning-coffee-did-it-taste-like-mud-v6rfdmrrr92 http://grist.org/food/coffee-taste-like-dirt-thats-because-it-might-be/ " Using liquid chromatography, which identifies the individual chemical components of a mixture, the Brazilian scientists found wheat, soy bean, brown sugar, barley, corn, and rice commonly interspersed with the grounded coffee they tested. Large amounts of wood and dirt were also prevalent, an issue not only for purists who prefer to drink their coffee black, but for those with potential allergies to the unknown additives. As TIME reports, the scientists are identifying the rogue coffee with increasing accuracy:" http://www.bodyandsoul.com.au/health/health-news/is-there-wheat-hidden-in-your-coffee/news-story/a3d53a7c36b76156f08d89eab6a396b3   -----   I have also read other references to coffee upsetting those with celiac.   Personally I have a family history of officially diagnosed celiac even though I have never been diagnosed myself..then again Ive never been properly tested. My drs just keep saying the following symptoms are anxiety and wont refer me to a gastroenterologist for:   Loss of bowel control, pale coloured stools, severe bloating, passing undigested food, ataxia, vertigo, migraine headaches, feeling feverish, repeated ulcers on my tongue and in my mouth, feeling generally ill and sleep issues (mostly falling asleep when I dont want to but rarely insomnia).   Because they insist its anxiety as routine blood tests are normal they wont refer me to a gut dr. They did do a blood test for celiac once on my request but it came back negative. This does not phase me when it comes to my suspicians that gluten is an issue for me because:   1 I was on a gluten free diet at the time, hence why i was well enough to crawl to the gps office. 2 I have a family history of celiac 3 MY symptoms are alleviated by a gluten free, dairy free, oat free, corn free diet..and lately, coffee free it seems. Coffee has indeed become a problem for me recently. 4 I could not tolerate gluten based baby foods as an infant. I was admitted to hospital as a baby for being underweight because I was vomitting all my food up. They put me on gluten free formula and i was fine, stopped being sick and gained weight. I could have grown out of it but considering the symtpoms i get on a gluten based diet, i really doubt it.   -----   When it comes to the coffee, food manufacturers will do most anything to make profits if they think they can get away with it. We live in a world where money is most important and if they do get caught...they can always claim they have no idea how the barley got in there!    
    • If you have had a sleep study and been diagnosed, you have sleep apnea. It's definitely different than waking up to go to the bathroom. Are you using your cpap every night for The entire night. Naps too? SA can actually cause death so it's very Important for you to use it every time you sleep. Do you follow up with your doctor yearly? Sorry to sound like the SA police, but I know someone who died from it. He wasn't using his cpap anymore, thought it was uncomfortable.     What Is Sleep Apnea?   Sleep apnea (AP-ne-ah) is a common disorder in which you have one or more pauses in breathing or shallow breaths while you sleep. Breathing pauses can last from a few seconds to minutes. They may occur 30 times or more an hour. Typically, normal breathing then starts again, sometimes with a loud snort or choking sound. Sleep apnea usually is a chronic (ongoing) condition that disrupts your sleep. When your breathing pauses or becomes shallow, you’ll often move out of deep sleep and into light sleep.
    • Summer sausage, rope sausage or link sausage? what were the ingredients? Msg makes me dizzy.
    • I found it confusing as to whether this was gluten or free not.  However, I've not had gluten in two weeks now and had Hillshire Farms beef sausage this morning and my head is literally spinning.  I'm going to assume I shouldn't have eaten it.  It was good......but will avoid it from now on.
    • I've suffered with this for a very long time and never knew it was part of celiac. At age 13 I had the very first episode that I can recall.  Much later in life I had the bad peristalsis that accompanies celiac and would suffer for up to an hour after the initial symptoms began accompanying the D.  Mine would courteously wait until later in the mornings as I would get up at 4AM to get ready for work, and then it would burst upon the scene at about 7:30 AM with a vengeance.  Finally, 17 years ago, I did a search on my computer for causes for D and learned it could be caused by wheat, or celiac most likely.  Afterward I visited my MD who poopoo'd the idea that an adult could possibly have have celiac, her words "That's a children's disease".  She then sent me to gastro for a Sigmo, and it was then labeled IBS.   The symptoms continued until I got all the glutens out of my diet and then there was mostly quiet in my gut.  Then 10 years ago she sent me back to gastro to have a look at why it kept happening, had both upper & lower GI and the old Doc could not confirm anything as by then there was healing. Had it been caught back when I was 13, sure the food choices would have been plain foods instead of the cool pies and cookies offered at home, but better health. BUT, yes Night D does accompany celiac disease.
  • Upcoming Events