• Ads by Google:

    Get email alerts Celiac.com E-Newsletter

    Ads by Google:

       Get email alertsCeliac.com E-Newsletter

  • Announcements

    • admin

      Frequently Asked Questions About Celiac Disease   09/30/2015

      This Celiac.com FAQ on celiac disease will guide you to all of the basic information you will need to know about the disease, its diagnosis, testing methods, a gluten-free diet, etc.   Subscribe to FREE Celiac.com email alerts   What are the major symptoms of celiac disease? Celiac Disease Symptoms What testing is available for celiac disease? - list blood tests, endo with biopsy, genetic test and enterolab (not diagnostic) Celiac Disease Screening Interpretation of Celiac Disease Blood Test Results Can I be tested even though I am eating gluten free? How long must gluten be taken for the serological tests to be meaningful? The Gluten-Free Diet 101 - A Beginner's Guide to Going Gluten-Free Is celiac inherited? Should my children be tested? Ten Facts About Celiac Disease Genetic Testing Is there a link between celiac and other autoimmune diseases? Celiac Disease Research: Associated Diseases and Disorders Is there a list of gluten foods to avoid? Unsafe Gluten-Free Food List (Unsafe Ingredients) Is there a list of gluten free foods? Safe Gluten-Free Food List (Safe Ingredients) Gluten-Free Alcoholic Beverages Distilled Spirits (Grain Alcohols) and Vinegar: Are they Gluten-Free? Where does gluten hide? Additional Things to Beware of to Maintain a 100% Gluten-Free Diet What if my doctor won't listen to me? An Open Letter to Skeptical Health Care Practitioners Gluten-Free recipes: Gluten-Free Recipes Where can I buy gluten-free stuff? Support this site by shopping at The Celiac.com Store.

Steroids (For Allergies) And Endoscopy?

4 posts in this topic

I'm new here, but I've been reading this forum for a while. I'm seeing my doctor in two weeks to discuss celiac testing. I'm 37 years old and have had many, many symptoms for my whole life and was given a lot of misinformation whenever I asked previous doctors about celiac or food allergy testing. (One doctor told me that I'd have died as a child if I had undiagnosed celiac, and that it was a ridiculous idea and she'd never order the tests. Another doctor said that the incredibly itchy rash covering my entire torso, which I had for years on end, did not require further investigation and would go away as soon as I "stopped worrying about it so much".) I finally have a doctor who seems willing to take my concerns seriously, and I want to make sure my test results are as accurate as possible.


I've gotten mixed results with food allergy tests. I had clear positive skin pricks for wheat and several other foods, but negative blood allergy tests for those same foods. On my skin pricks, I had very large red flares around half the fruit and vegetable prick sites but no wheals; this was considered negative, but it was unusual and didn't just indicate general skin irritability because the saline control spot and half the others had no flare. Anyhow, the allergist concluded that I did not have a wheat allergy because of the negative IgE test, and she said the positive skin pricks were just from cross-reaction to environmental allergens (which I know I have). I'm not entirely confident about that assessment, but I've had so many weird and inconclusive test results for various things over the years that I'm used to it.


I stopped eating wheat after the allergy tests anyway, and within days many of my long-standing problems were definitely improving. After several weeks I started eating a little wheat again while taking antihistimines, and the symptoms returned. My stomach bloated up even more than before, and it looked like I was six months pregnant just from one meal of wheat. Having this reaction while on antihistimines seemed like pretty clear evidence that a wheat allergy alone (if indeed I have one) couldn't be the whole problem. At that point I switched to a new primary care doctor and started eating small amounts of wheat again every day because I want the celiac tests to be accurate. 


My immediate question is about the effect that small amounts of topical cortisone cream or a one-time pill dose of prednisone might have on celiac blood tests or an endoscopy.


I've been using a tiny dab of cortisone cream on a rash spot on my face every day. It doesn't make the rash go away, but it makes it less red. I can do without it, but it's a tiny amount and the rash is embarrassing because it's so visible on my face. Should I stop using it completely? For how long?


Also, I get monthly allergy shots for environmental allergens, and after an full year on the maintenance dose my whole arm still swells up hugely after the shot unless I take two antihistimines and one prednisone pill first. I started to have breathing difficulty after the shot without the prednisone once, and it was scary so my allergist said to just routinely take the predinose on shot days from now on. I can take up to four doses on prednisone if needed, but I've never needed more than two and I'm willing to stick to just one even though it means dealing with the swelling longer. However, I'm very nervous about doing the allergy shot without that one dose. I do have an epi-pen and could treat myself for anaphylaxis until I got to a hospital, but that's the last thing I need right now! If I go more than 42 days between shots, the whole five-year process becomes invalid and I'd have to start all over again. My environmental allergies are pretty severe, so I really don't want to abandon the process. I can try to schedule the celiac tests so they're as close as possible to the 42-day cut-off since I've last had prednisone, but will one dose of prednisone five weeks earlier make the test results invalid? And do steroids affect blood test results too, or just the endoscopy? 



Share this post

Link to post
Share on other sites
Ads by Google:
Ads by Google:

I have heard that steroids can affect celiac endoscopic testing but I have no idea where or if it is even correct... Perhaps others can point you in the right direction on that.


It sounds like you have a reasonable plan for the celiac testing. Perhaps you can contact your doctor about the effect the steroids will have on testing? Perhaps contact the doctors performing the endoscopy too.


Good luck with testing. Try not to minimize your gluten intake too much before testing so your results are as accurate as possible.


Share this post

Link to post
Share on other sites

Yes, steroids can give a false negative for celiac testing. I have a citation somewhere - I think it's in the new guidelines for dxing children without scoping. There's a flow chart and at the end is "steroid use?" under a negative tests when all evidence points to positive.

I'm not in a position to search for the doc now, but you may find it by searching.

I don't know how much steroid is enough to interfere with testing. I've wondered, too. I was given mega doses, so it wouldn't have mattered. I also used topical cream and while the concentration was low, the results when the cream was withdrawn was dramatic. So, I don't know how much was circulating but it had a massive effect on my dh.

Perhaps you could time testing right at one month after your shot? Perhaps try going without the cream and see how it goes?


Share this post

Link to post
Share on other sites

Thank you both!

I've stopped using the cortisone cream for now and will try to make the best of it until I'm tested. I'm sure my allergist will say to definitely take the prednisone pill, even if my other doctor says it's better not to. If necessary, I'll just try to space the testing out as far as possible after my last allergy shot, though I have limited control over how things are scheduled.


Share this post

Link to post
Share on other sites

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now

  • Forum Statistics

    • Total Topics
    • Total Posts
  • Member Statistics

    • Total Members
    • Most Online

    Newest Member
  • Popular Now

  • Topics

  • Posts

    • I am sorry that you are sick!  Ennis has offered some great advice.  With small children, they can be glutening you.  I recall member Jebby getting glutened by her kids.  She worked full time as a neonatologist (premie doctor) and her kids would give her slobbery, adorable kisses, etc.  Jebby had the household go gluten free.  That might be something to consider.  
    • Hmm... my massage therapists use aromatherapy and specifically ask you to inhale several times while they hold it very close to your face and I do have them rub my face (although some people don't like that and don't have it done.) Lotion also ends up on your hands which you could transfer to food you eat afterwards if you haven't washed your hands well (obviously hand washing is key!) But I don't think that is too far of a stretch to think it *could* be injested and to double check to be sure the products used are gluten-free.  And at a salon I realize that they'd wash my hair tilted back but what about product(s) being spritzed on your hair when styled? Rare yes, but I do know I've "tasted" those products before! Ick.  
    • I was noticeably gray at 18. Both of my parents went gray young as well. I have no thyroid problems and I'm pretty sure my celiac issues didn't start until 20 years later....   I started dying it when I was 28. I wanted to look more professional!
    • Celiac disease is not diagnosed by symptoms alone. Why?  There are over 300 of them and many, if not all, overlap with other autoimmune issues or other illnesses.  Learn more about proper testing: http://www.cureceliacdisease.org/screening/ I am formally diagnosed.  My hubby is not.  His mis-informed doctors told him 16 years  ago to give up gluten.  It worked, but now we do not really know if he has celiac disease or not.  He will be the first to say that I get WAY more support from family, friends and medical.   I am sorry at your doctor gave you the wrong advice.  Now, you must decide if testing is worth pursuing.  I wish you well.  
    • I am considering having my brother - who inherited Daddy's power woodworking tools - plane down my cutting boards and sand the edges enough so I can keep them. The spoons and soup stirring things though will have to be decorative. Breaks my heart. I've had good luck with Merle Norman cosmetics. They have a listing of things that are gluten-free that has helped me. My local store owner was able to get the list and knows what I can use and what I can't.
  • Upcoming Events