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      Frequently Asked Questions About Celiac Disease   09/30/2015

      This Celiac.com FAQ on celiac disease will guide you to all of the basic information you will need to know about the disease, its diagnosis, testing methods, a gluten-free diet, etc.   Subscribe to FREE Celiac.com email alerts What are the major symptoms of celiac disease? Celiac Disease Symptoms What testing is available for celiac disease? - list blood tests, endo with biopsy, genetic test and enterolab (not diagnostic) Celiac Disease Screening Interpretation of Celiac Disease Blood Test Results Can I be tested even though I am eating gluten free? How long must gluten be taken for the serological tests to be meaningful? The Gluten-Free Diet 101 - A Beginner's Guide to Going Gluten-Free Is celiac inherited? Should my children be tested? Ten Facts About Celiac Disease Genetic Testing Is there a link between celiac and other autoimmune diseases? Celiac Disease Research: Associated Diseases and Disorders Is there a list of gluten foods to avoid? Unsafe Gluten-Free Food List (Unsafe Ingredients) Is there a list of gluten free foods? Safe Gluten-Free Food List (Safe Ingredients) Gluten-Free Alcoholic Beverages Distilled Spirits (Grain Alcohols) and Vinegar: Are they Gluten-Free? Where does gluten hide? Additional Things to Beware of to Maintain a 100% Gluten-Free Diet Free recipes: Gluten-Free Recipes Where can I buy gluten-free stuff? Support this site by shopping at The Celiac.com Store.
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Mthfr Gene Mutation
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7 posts in this topic

My doctor is giving me this gene test...from what I read it can affect the bodies ability to detox...detox what exactly i'm not sure but I may have a problem with salicylates and I did read chemical sensitivities can happen as a result of this. I don't know if I completely understand the whole thing yet only that they often give methyl b12....does this help with methylation? Does it detox whatever is going on in your body? A little confused. Either way..anyone else have this gene mutation?

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Yes a specific kind of b12 because it bypasses a certain stage of conversion that people with this mutation can't do.

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methylcobalamin, that is B12 that is already methylated, which is the usable form.  If you take the cyano- variety, the body needs break the cyano- molecule off, ad then methylate the cobalamin.  most persons can do that, but those with that particular gene mutation can't.

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Right. From what I understand the defective gene is actually very common...about 40% of the population is suppose to have it.

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I've been reading up on it. Not sure how much is real science and how much is interweb psudoscience. It sounds like many people with this issue has had success with the Methy version of B-12 along with l-methylfolate as part of their treatment "protocol", along with a bunch of other vitamins and minerals that are of course linked directly to websites that sell them. Taking those two above vitamins (available from any health supplement store) did help me with my fatigue and mental fog... not  totally but maybe 50-75%. The biggest thing is that it doesn't take me an hour to get out of bed anymore. I actually got out of bed before my alarm! which has never happened in my life!

 

anyway.. There seems to be quite a few overlaping symptoms between mthfr gene mutation and gluten intolerance.. and a common recommendation on mthfr treatment is to actually eliminate gluten and casein. I wonder if there is some kind of link between the two????? 

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Wouldn't shock me. The defect can lead to any number of issues. A friend of mine has it and has blood clotting issues. It tends to affect everyone differently.

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