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Help me!! interpret my blood panel results


Lgerb6

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Lgerb6 Rookie

The Dr said via phone that it is likely I have celiac. I received more numbers today. Do these show a definitive positive? I think they are awaiting one more celiac result. I do see a GI in a couple weeks. See below:

Gliadin igA 63.9 with standard range <15

Gliadin igG 177.4 with standard range <15

Tissue Transglutaminase iga 208.3 with standard range <15

Tissue Transglutaminase igg 40.0 with standard range <15

Immuniglobin A 125 with reference range 70-100

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kareng Grand Master
1 hour ago, Lgerb6 said:

The Dr said via phone that it is likely I have celiac. I received more numbers today. Do these show a definitive positive? I think they are awaiting one more celiac result. I do see a GI in a couple weeks. See below:

Gliadin igA 63.9 with standard range <15

Gliadin igG 177.4 with standard range <15

Tissue Transglutaminase iga 208.3 with standard range <15

Tissue Transglutaminase igg 40.0 with standard range <15

Immuniglobin A 125 with reference range 70-100

I don't think it could be anything else with numbers that high!

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cyclinglady Grand Master

Your doctor is wise.  I bet your doctor said “likely”, because he wants the GI to confirm!  So, keep eating gluten until you discuss with your GI.  In the meantime, learn about celiac disease and treatment.  

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Lgerb6 Rookie

Thank you!!!

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squirmingitch Veteran

That's about the most definitive positive across the board that I've ever seen. You're way positive on every one. Keep eating gluten every single day until the endoscopy! You don't have to eat a ton, 1 or 2 slices of gluten bread per day will do it. Orrrrrrrrrrr you could take this time to pig out on all of your favorite gluten foods to say goodbye to them. 

Ultimately, those foods will become a distant memory. There are gluten free replacements for literally everything but for 6 months to a year, you will need to eat whole foods & none of the processed stuff so you can heal.

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Lgerb6 Rookie

My allergist did suggest I cut out gluten right away, but I’ll call the GI tomorrow and discuss that. Thank you!

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Gemini Experienced

My panel was the same as yours........all tests positive by large numbers so you can consider yourself a Celiac.  Are you very symptomatic?

I will add that I did not eat Whole Foods exclusively when healing.  I needed to gain weight badly so ate gluten-free bread and a few other things that seemed to agree with me.  Never had a problem once I went gluten free, except to discover that I had a problem with dairy also. But I healed well and all is good.  You'll be fine now that you know what the problem is.  Good luck!  :)

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squirmingitch Veteran
43 minutes ago, Lgerb6 said:

My allergist did suggest I cut out gluten right away, but I’ll call the GI tomorrow and discuss that. Thank you!

From the Chicago Celiac Disease Center which is one of the premier celiac disease research & treatment centers in the world:

Are you scheduled for a biopsy? Are

you eating gluten?

Any changes in your diet can affect the accuracy of your biopsy results. It is necessary for you to be eating gluten every day for at least 4-8 weeks before the procedure. If you are scheduled for a biopsy and are not eating gluten, talk to your doctor about what is necessary to obtain accurate results. If you have
a biopsy and have eaten gluten only a short time before the test, you and your physician will not know if a negative test result is accurate or due to your diet.

Here's a link:

Open Original Shared Link

Also, you might want to read this:

Open Original Shared Link

 

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Lgerb6 Rookie

Very helpful. Thank you!

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Lgerb6 Rookie
11 hours ago, Gemini said:

My panel was the same as yours........all tests positive by large numbers so you can consider yourself a Celiac.  Are you very symptomatic?

I will add that I did not eat Whole Foods exclusively when healing.  I needed to gain weight badly so ate gluten-free bread and a few other things that seemed to agree with me.  Never had a problem once I went gluten free, except to discover that I had a problem with dairy also. But I healed well and all is good.  You'll be fine now that you know what the problem is.  Good luck!  :)

I am symptomatic, yes. Pretty much everything except weight loss!

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Agquick Newbie

Can I just ask what Is the difference between tt igg and tt Iga? 

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squirmingitch Veteran

An autoimmune disease can occur when the body's immune system mistakenly perceives a nonthreatening substance. In the case of people with celiac disease, gluten (a protein found in wheat, barley, rye, and oats) is seen as a foreign invader and is attacked by the immune system. This immune system response in celiac disease also involves the production of antibodies directed against an enzyme normally present in the intestines called tissue transglutaminase (tTG).

In celiac disease, the body produces two types of antibodies that attack tTG: immunoglobulin A (IgA) and immunoglobulin G (IgG). Measuring the IgA form of tTG antibody in the blood is more useful in detecting celiac disease because it's made in the small intestine, where gluten causes inflammation and irritation in sensitive people.

Levels of the IgG form of tTG antibody, on the other hand, are less specific to celiac disease, but may still be useful in diagnosing the condition in people who are unable to make normal amounts of IgA antibodies.

From: 

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Agquick Newbie

Ah ok thank you! Only because my ttg came back at 41 and am now waiting to see a doctor, not shure what all the numbers mean! 

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squirmingitch Veteran

It only takes on positive on the celiac serum panel to move to an endoscopic biopsy. A positive is a positive, even if it's 1/2 point above the normal range. Do not dwell on your 41 number. You have so many highs that are shockingly high that barring wearing a white coat & having a medical degree hanging on the wall; we would say you have celiac.

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