• Join our community!

    Do you have questions about celiac disease or the gluten-free diet?

  • Ads by Google:

    Get email alerts Subscribe to Celiac.com's FREE weekly eNewsletter

    Ads by Google:

       Get email alertsSubscribe to Celiac.com's FREE weekly eNewsletter

  • Announcements

    • admin

      Frequently Asked Questions About Celiac Disease   09/30/2015

      This Celiac.com FAQ on celiac disease will guide you to all of the basic information you will need to know about the disease, its diagnosis, testing methods, a gluten-free diet, etc.   Subscribe to Celiac.com's FREE weekly eNewsletter   What are the major symptoms of celiac disease? Celiac Disease Symptoms What testing is available for celiac disease?  Celiac Disease Screening Interpretation of Celiac Disease Blood Test Results Can I be tested even though I am eating gluten free? How long must gluten be taken for the serological tests to be meaningful? The Gluten-Free Diet 101 - A Beginner's Guide to Going Gluten-Free Is celiac inherited? Should my children be tested? Ten Facts About Celiac Disease Genetic Testing Is there a link between celiac and other autoimmune diseases? Celiac Disease Research: Associated Diseases and Disorders Is there a list of gluten foods to avoid? Unsafe Gluten-Free Food List (Unsafe Ingredients) Is there a list of gluten free foods? Safe Gluten-Free Food List (Safe Ingredients) Gluten-Free Alcoholic Beverages Distilled Spirits (Grain Alcohols) and Vinegar: Are they Gluten-Free? Where does gluten hide? Additional Things to Beware of to Maintain a 100% Gluten-Free Diet What if my doctor won't listen to me? An Open Letter to Skeptical Health Care Practitioners Gluten-Free recipes: Gluten-Free Recipes

Gene Result Question

Rate this topic

Recommended Posts

I finally got our son's stool and gene test back from Enterolab. Here are the results. I have a question about the gene results - Does this mean he has multiply genes or just subtypes . It is very confusing.

Gluten sensitivity stool test - 13 units (shows sensitivity)

All other tests for normal

Gene test:

Molecular analysis - HLA-DQB1 *0201, 0602

Serologic analysuis: HLA-DQ 2, 1 (subtype 2,6)

It looks like he needs to be on the diet. Any comments? Thanks

Share this post

Link to post
Share on other sites
Ads by Google:
Ads by Google:

Within each set of genes there are many subtypes. The number *0201 is the exact gene your son has. Then withthin the grouping of *02xx genes there are subtypes. Same with any of the genes, so the *0602 is the DQ1, subtype 6.

The genes pan out as follows:

DQB1 *0201 = DQ2, subtype 2

DQB1 *0602 = DQ1, subtype 6 (OR it can also be referred to as DQ6)

He has 2 genes, one from you and one from your husband. BOTH of these genes predispose someone to a gluten sensitivity. DQ2 is associated with celiac disease and gastro problems, while DQ1 is associated with gluten induced neurological problems. I would definitely take a look at you and your husband and any other children.

There are some pretty good explanations on these genes and their typing on the Braintalk forum. Here is one post that gives some links to help understand your gene naming:

Help with interpreting genetic results.

Share this post

Link to post
Share on other sites

Thank you , thank you, thank you. I thought no one was ever going to reply!! That was very helpful. and actually cleared up somethings. It was very interesting that you said that that the DQ1 (I think) was tied to nuerological problems because he has many of these that we haven't been able to figure out why. Thank you so much!

Share this post

Link to post
Share on other sites

Hi ADevoto: Enterolab usually adds an interpretation of test results with their lab test results email. What did they say about the genetic results? If you have questions, write to Dr. Fine at E-lab. He WILL answer your email promptly. ;)


Share this post

Link to post
Share on other sites

They just said that the HLA - DQ2 is the main gene that predisposes to gluten sensitivity and celiac. Can also prodisse to microscopic colitis and other autoimmune syndromes. Nothing about DQ1. But Dr. Fine did return an email to me that just said the above and that DQ1 usually doesn't lead to celiac but to sensitivity only.

I just wanted to understand more. I know that there is high % of people that are celiac that have the DQ2 gene but I really need to find the statistic that show what % of people that have the gene actually become celiac. Need more "proof" for my husband.

Share this post

Link to post
Share on other sites
Ads by Google:

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now


  • Forum Statistics

    • Total Topics
    • Total Posts
  • Member Statistics

    • Total Members
    • Most Online

    Newest Member
    Melissa Keipert
  • Popular Now

  • Topics

  • Posts

    • In Austin, Wildwood Bakehouse and Wilder Wood Restaurant are totally gluten free.  I had the chicken fried steak and gravy and onion rings!!!  Awesome!!!  
    • If you yourself have Celiac's disease, you probably shouldn't give gluten-free sandwiches to the homeless, because they're disgusting. Your male neighbor doesn't need tampons. That sort of reasoning should be applied. But you must always remember that the Gospel requires you to treat other people ... View the full article
    • Hi there I have this exact same thing.. however I don’t have celiac that I know of.. I found this when google searching for what the heck is wrong with my face.  I was wondering if you ever found out.. or if it just went away. Thanks
    • I have read the newbie 101 and have been careful about reading labels. I'm the only one that's gluten free in my household, so they could be contaminating me. I was eating gluten for 6 weeks after my blood test because it took that long to get an official diagnosis and my GP told me to still be eating it for the tests to be accurate. It was probably too soon to retest, but the test was accidentally ordered by the lab. I have been having an increase in joint pain over the last couple months and my rheumatologist ordered lab work. The lab saw the celiac panel had been ordered, but didn't see results so they added it on because they thought it still needed done.  My gut issues are starting to get better, but I'm thinking the joint pain might have been from the celiacs because all of the rheumatoid tests came back normal for the first time in twenty years.
    • Hi and Welcome to the Forum.  I am glad that you are here! As with a lot of things in life, try not to compare yourself to other people. You are trying to be the best version of yourself - not Jill, Annie, or Maya.  People make a lot of foolish decisions in the world and it does not mean that you should do it too.  Also, many people are gluten free for a lot of reasons that aren't celiac. One of my best friends has gluten sensitivity but not celiac.  He eats a lot of food that I won't touch due to possible cross contamination which he doesn't worry about too much.  Be true to yourself and keep your self healthy.  It is so hard, but it's better than getting sick! I hate not being able to partake in yummy food at parties, but I have learned what junk food I can eat.  I will make sure to buy some tortilla chips or Fritos for picnics.  I freeze gluten-free cupcakes to eat when we celebrate birthday parties (I can just take one out of the freezer and go).  I make sure to take a dish to share to potlucks.  I ask permission at restaurants and parties to bring my own food - no one has ever said no, and when there is a time to celebrate, I splurge on something I really like.  Fortunately, there are a lot of gluten-free foods that I really like. Do i miss pizza and really good burger? YES! And sometimes, I still feel awkward, but life is so much more than food.
  • Upcoming Events