• Ads by Google:
     




    Get email alerts Celiac.com E-Newsletter

    Ads by Google:



       Get email alertsCeliac.com E-Newsletter

  • Announcements

    • admin

      Frequently Asked Questions About Celiac Disease   09/30/2015

      This Celiac.com FAQ on celiac disease will guide you to all of the basic information you will need to know about the disease, its diagnosis, testing methods, a gluten-free diet, etc.   Subscribe to FREE Celiac.com email alerts   What are the major symptoms of celiac disease? Celiac Disease Symptoms What testing is available for celiac disease? - list blood tests, endo with biopsy, genetic test and enterolab (not diagnostic) Celiac Disease Screening Interpretation of Celiac Disease Blood Test Results Can I be tested even though I am eating gluten free? How long must gluten be taken for the serological tests to be meaningful? The Gluten-Free Diet 101 - A Beginner's Guide to Going Gluten-Free Is celiac inherited? Should my children be tested? Ten Facts About Celiac Disease Genetic Testing Is there a link between celiac and other autoimmune diseases? Celiac Disease Research: Associated Diseases and Disorders Is there a list of gluten foods to avoid? Unsafe Gluten-Free Food List (Unsafe Ingredients) Is there a list of gluten free foods? Safe Gluten-Free Food List (Safe Ingredients) Gluten-Free Alcoholic Beverages Distilled Spirits (Grain Alcohols) and Vinegar: Are they Gluten-Free? Where does gluten hide? Additional Things to Beware of to Maintain a 100% Gluten-Free Diet What if my doctor won't listen to me? An Open Letter to Skeptical Health Care Practitioners Gluten-Free recipes: Gluten-Free Recipes Where can I buy gluten-free stuff? Support this site by shopping at The Celiac.com Store.

Lab Results-Confused
0

9 posts in this topic

I got my lab results emailed to me today from my biopsy but I'm not quite sure what they mean. Clearly, there is damage but I'm wondering whether it confirms the drs guess of mild celiac based on my blood results of 83 on the ttg or whether the damage is more severe. Any thoughts?

FINAL DIAGNOSIS DUODENUM BIOPSY: FLATTENED MUCOSA WITH CHRONIC INFLAMMATION (SEE

MICROSCOPIC).

PATHOLOGIST: Mullen MD, Dennis L. Electronically Signed: 08/29/2011

SOURCE A) a. duodenum

PRE-OPERATIVE DIAGNOSIS celiac disease

GROSS APPEARANCE Received in a container labeled with the patient's name and "duodenum" are

0.3 and 0.4 cm soft tissue fragments, AE/(2).

MICROSCOPIC EXAMINATION This flattened mucosa includes only a few blunt villi. The lamina propria

shows a mixed inflammatory cell infiltrate. The differential diagnosis

includes celiac disease, peptic ulcer disease, and nonspecific duodenitis.

0

Share this post


Link to post
Share on other sites
Ads by Google:
Ads by Google:


I'm not a dr. or expert, but it sounds like the radiologist is saying that you have severe damage to you villi. He only found a few blunt villi on the specimens your GI took. The radiologist diagnosed you with celiac disease (not mild), and peptic ulcer disease, which will undoubtedly improve with a totally gluten-free diet. Thanks for posting, I'm going to ask my gastro for my radiologist report, even though it's been over a year since I had it.

The good news and bad news is that you have celiac disease. Wish you well and hope all of your first degree relatives get tested.

0

Share this post


Link to post
Share on other sites

I'm not a dr. or expert, but it sounds like the radiologist is saying that you have severe damage to you villi. He only found a few blunt villi on the specimens your GI took. The radiologist diagnosed you with celiac disease (not mild), and peptic ulcer disease, which will undoubtedly improve with a totally gluten-free diet. Thanks for posting, I'm going to ask my gastro for my radiologist report, even though it's been over a year since I had it.

The good news and bad news is that you have celiac disease. Wish you well and hope all of your first degree relatives get tested.

Thank you, that's extremely helpful. It sounded both like it was severe and also like it was mild in that the only damage was a few blunted villi so more experienced interpretations are helpful. I'm okay with having celiac (and honestly, I was kind of hoping for a very clear biopsy to avoid any ambivilence). Where do you get the peptic ulcer from?

0

Share this post


Link to post
Share on other sites

I don't know, Marilyn. The way I read it, it is a bit of a mixed bag. I looked up 'differential diagnosis' to confirm in my mind what it means:

Differential diagnosis: The process of weighing the probability of one disease versus that of other diseases possibly accounting for a patient's illness. The differential diagnosis of rhinitis (a runny nose) includes allergic rhinitis (hayfever), the abuse of nasal decongestants and, of course, the common cold.

So the differential diagnosis is weighing what disease process is actually causing the symptoms found. He talks about flattened mucosa; it's not clear if he's including the villi in the mucosa, and when he says ' only a few blunt villi', does he mean that's all he found or that's all that's left?? So I read that he is trying to determine which of the three caused the symptoms: The differential diagnosis includes celiac disease, peptic ulcer disease, and nonspecific duodenitis.

So is he meaning to diagnose all three conditions or differentiate between them? given that the final diagnosis is given as:

FINAL DIAGNOSIS DUODENUM BIOPSY: FLATTENED MUCOSA WITH CHRONIC INFLAMMATION

I am as confused as the poster. :rolleyes:

0

Share this post


Link to post
Share on other sites

I asked a lab tech friend to take a look and she read it as saying there was severe damage. I'm leaning towards that as well because he first says the mucosa is flattened.

0

Share this post


Link to post
Share on other sites
Ads by Google:


I read it as saying mild damage. Inflammation, flattening, but only a few villi are blunted. Notice there is no crypting mentioned, which is the hallmark of severe celiac. Also, if the damage were severe, the pathologist would have firmly diagnosed celiac rather than saying it's possibly peptic ulcer disease or duodenitis.

I believe it confirms your doctors hunch of celiac disease that's not gotten too severe yet.

0

Share this post


Link to post
Share on other sites

Either way, it is a very poorly written report to create so much confusion :P

0

Share this post


Link to post
Share on other sites




Either way, it is a very poorly written report to create so much confusion :P

True. That fellow needed to take a couple English classes along with his pre-med. :lol:

0

Share this post


Link to post
Share on other sites

It doesn't seem to complicated to me. It's been my experience that radiologists, pathologists, etc only report what they see, they don't diagnose. So...

FINAL DIAGNOSIS DUODENUM BIOPSY: FLATTENED MUCOSA WITH CHRONIC INFLAMMATION (SEE

MICROSCOPIC).

This is not a diagnosis in the normal sense. This is a description of the damage to your intestine.

PATHOLOGIST: Mullen MD, Dennis L. Electronically Signed: 08/29/2011

SOURCE A) a. duodenum

Seems straightforward. This was a duodenal endoscopy.

PRE-OPERATIVE DIAGNOSIS celiac disease

This is what your doctor suspected you had, your diagnosis before the endoscopy.

MICROSCOPIC EXAMINATION This flattened mucosa includes only a few blunt villi. The lamina propria

shows a mixed inflammatory cell infiltrate. The differential diagnosis

includes celiac disease, peptic ulcer disease, and nonspecific duodenitis.

This is the important part. As others have said, there's flattened mucosa but only a few blunted intestinal villi, etc. Then, the pathologist lists the diseases that can cause that damage.

Since you went for the endoscopy to confirm Celiac, and have results consistent with Celiac, this is almost certainly a positive result. You should call the doctor who sent you for the endoscopy to get his/her feedback and to make sure you've ruled out peptic ulcers as a causative agent.

It's sometimes easier to think of a result like this as not really designed for you to read. It's really intended for your doctor which is why it seems unclear. Call your doctor to discuss, and stop eating gluten if you haven't already.

1

Share this post


Link to post
Share on other sites

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!


Register a new account

Sign in

Already have an account? Sign in here.


Sign In Now
0

  • Forum Statistics

    • Total Topics
      107,391
    • Total Posts
      935,838
  • Member Statistics

    • Total Members
      65,077
    • Most Online
      3,093

    Newest Member
    MayonnaisePlease
    Joined
  • Popular Now

  • Topics

  • Posts

    • First have you been tested for celiac disease? Any doctor can do the blood test but you have to be eating gluten on a daily basis for the test to work, nut much just a half slice of bread a day. You should get this tested, the high constipation, coughing stuff up was very common for me before diagnosis. The coughing stuff up for me was from a allergy that developed I did not know of, the mucus was draining down my throat and choking me at times, and was constantly running a fever and night sweats. I was constipated for 4-10 days average back then and drinking plenty of liquids did not help in the least. Your gut rumbling could be many things, celiac is one, SIBO is another especially with the bad breath. in your case it could be related to constipation causing rotting, fermenting, and bacterial overgrowth of the waste in your system. Now to deal with the immediate symptoms, your constipation is also a sign of magnesium deficiency, I imagine you might have noticed some other symptoms from these. Now normally I would suggest either the Natural Vitality Calm or Doctors Best which is easier on the stomach. In your case I straight up suggest the Natural Vitality Calm it is a Magnesium Citrate and works a bit like a laxative. Start with 1/4 tsp twice a day in a beverage, I like the orange or the cherry in a hot green tea or you can try it in a juice. Up the dose slowly over a periods of a week to the full dose or perhaps a little more til you get a bit looser stool.     You mentioned the mucus in the stool 2 things cause this normally. Undigested fats, and inflammation/irritation causing the body to produce the mucus to help defend itself and purge the irritants. A doctor can probably tell you more but I might suggest a digestive enzyme in the mean time. I like to use a super papaya enzyme before and after a meal, find them on amazon. Jarrow also makes full enzyme complex that can help. Other thoughts if your on dairy, stop, with the constipation, and other issues this is a equation for trouble and you can reintroduce it in a few months when you clear up and see if it bothers you then. The bad breath can be a sign of lactose intolerance/digestive issues with dairy also. If it comes you you have celiac then you would have your explanation here as the villi which produce the enzymes to break down lactose are damaged/destroyed first causing most to develop a temporary lactose intolerance which for some goes away after a few months of healing. B-vitamin folic acid, and niacin will be a huge help also with some things. but will we get into that a bit later feel free to look up Liquid Health Stress & Energy if you thing it might be relevant at this point it is what I use 3 times a day with another blend they have.
    • Some of your symptoms sound like my ulcers.  I take carafate before every meal now and they are much better.  I have 3 ulcers possibly caused by taking iron supplements.  They are worse when I eat spicy food and dairy. I might be wrong but for your sake I hope it's just ulcers.  They were found by endoscopy.
    • The yellow is probably fat you are not absorbing.  The pain could be from your intestines being inflamed.  Go see the gastroenterologist.  The ER did not help me with any of those symptoms.  Good thing it's clear so you know it's not your appendix or any other vital organ.  It takes time but probiotics, bone broth and  vitamin D and b 12 help. My pain was mainly my muscles giving out from the malabsorption.
    • Hi, this has been a postcode lottery for some time, some health authorities support it others don't. The govt has recently indicated that doctors should no longer prescribe food to celiacs, you should check with your local GP to see if they are still doing this or not. if you want some advice on where to shop just ask  
    • @CleoTheLeoI've learned that I have a sluggish liver and that before trying to cleanse the liver, I need to make sure that the gall bladder is clear and working well, as well as the gut, so that when the liver is detoxing, the toxic wastes have an elimination route. Dr. Lam explains so many things in detail in his articles. https://www.drlam.com/blog/sluggish-liver-and-adrenal-fatigue/7854/.
  • Upcoming Events