• Ads by Google:
     




    Get email alerts Celiac.com E-Newsletter

    Ads by Google:



       Get email alertsCeliac.com E-Newsletter

  • Announcements

    • admin

      Frequently Asked Questions About Celiac Disease   09/30/2015

      This Celiac.com FAQ on celiac disease will guide you to all of the basic information you will need to know about the disease, its diagnosis, testing methods, a gluten-free diet, etc.   Subscribe to FREE Celiac.com email alerts What are the major symptoms of celiac disease? Celiac Disease Symptoms What testing is available for celiac disease? - list blood tests, endo with biopsy, genetic test and enterolab (not diagnostic) Celiac Disease Screening Interpretation of Celiac Disease Blood Test Results Can I be tested even though I am eating gluten free? How long must gluten be taken for the serological tests to be meaningful? The Gluten-Free Diet 101 - A Beginner's Guide to Going Gluten-Free Is celiac inherited? Should my children be tested? Ten Facts About Celiac Disease Genetic Testing Is there a link between celiac and other autoimmune diseases? Celiac Disease Research: Associated Diseases and Disorders Is there a list of gluten foods to avoid? Unsafe Gluten-Free Food List (Unsafe Ingredients) Is there a list of gluten free foods? Safe Gluten-Free Food List (Safe Ingredients) Gluten-Free Alcoholic Beverages Distilled Spirits (Grain Alcohols) and Vinegar: Are they Gluten-Free? Where does gluten hide? Additional Things to Beware of to Maintain a 100% Gluten-Free Diet Free recipes: Gluten-Free Recipes Where can I buy gluten-free stuff? Support this site by shopping at The Celiac.com Store.

Only Igg High....am A Celiac?
0

13 posts in this topic

Was told I was not Celiac by my GI. I went back to gluten. I feel horrible. Nauseaus all day plus much more. I dug and found my old results. So do you think I have Celiac?

Found my old results (Oct/06)

Gliadin Antibody IGG 31 High Range <11

Gliadin Antibody IGA 6 Range <6

Reticulin igg ab <1:10 Range <1:10

Reticulin IGA AB <1:10 Range <1:10

Tissue Transglut. IGA <3 Range <5

Then found 03/07/11 Everything the same but Gliadin IgG 23.4 High Range <10

What does it mean that eveything is normal BUT the Gliadin IgG?

0

Share this post


Link to post
Share on other sites
Ads by Google:
Ads by Google:


Was told I was not Celiac by my GI. I went back to gluten. I feel horrible. Nauseaus all day plus much more. I dug and found my old results. So do you think I have Celiac?

Found my old results (Oct/06)

Gliadin Antibody IGG 31 High Range <11

Gliadin Antibody IGA 6 Range <6

Reticulin igg ab <1:10 Range <1:10

Reticulin IGA AB <1:10 Range <1:10

Tissue Transglut. IGA <3 Range <5

Then found 03/07/11 Everything the same but Gliadin IgG 23.4 High Range <10

What does it mean that eveything is normal BUT the Gliadin IgG?

Well, first of all, since they do not appear to have done a total serum IgA, none of the IgA results mean a thing. If your total IgA is insufficient, ALL your IgA tests will most likely be low.

Second, your body is making antibodies against gluten. Your body does not like gluten. Your doc is a twit who should have done further testing. Especially considering you feel sick while eating gluten!

We can't answer the question definitively because we are not doctors, but there is an extremely high likelihood that yes, in spite of what your doctor said, you might have celiac.

Is there anything on your lab report that indicates whether the gliadin antibodies are "deamidated gliadin peptides"? Those are newer and more sensitive/specific than the old AGA (anti-gliadin antibody) tests. If your test was DGP, the likelihood is even higher for celiac.

0

Share this post


Link to post
Share on other sites

Thank you. I am going to a new Dr tomorrow.

Nothing else on the test results. I plan to get retested IF my insurance will cover it. Last visit the dr only used promethius and my insurance wouldnt pay. They said it would be about $1000!

Can I assume that with high IGG I am gluten intolerant? Not necessarily celiac?

0

Share this post


Link to post
Share on other sites

Thank you. I am going to a new Dr tomorrow.

Nothing else on the test results. I plan to get retested IF my insurance will cover it. Last visit the dr only used promethius and my insurance wouldnt pay. They said it would be about $1000!

Can I assume that with high IGG I am gluten intolerant? Not necessarily celiac?

Well, you can probably safely assume gluten intolerance at this point. Gluten is obviously making you feel sick. It's hard to say "celiac" for sure, because the IgG antibodies are less specific than the IgA ones, and without the EMA or TtG being positive, there is a chance your IgG elevation could be from another condition (see paragraph below). Still, you can see, there is a 91% chance it IS celiac.

Unfortunately, that leaves you in the boat of "maybe yes, maybe no". I've seen you wrestling with this on some other threads. If you are going to do more testing, you really need to make sure they do the total IgA along with everything else.

Gluten intolerance is a real condition, and can have a lot of negative effects on your life just like full-blown celiac; just without the flattened villi. Do you need a hard-copy celiac diagnosis for some reason?

Here's an explanation of the antibodies from an article on this site:

Anti-Gliadin Antibodies:

Both IgA and IgG anti-gliadin antibodies (AGA) are detected in sera of patients with gluten sensitive enteropathy (celiac disease). IgG anti-gliadin antibodies are more sensitive but are less specific markers for disease compared with IgA class antibodies. IgA anti-gliadin antibodies are less sensitive but are more specific. In clinical trials, the IgA antibodies have a specificity of 97% but the sensitivity is only 71%. That means that, if a patient is IgA positive, there is a 97% probability that they have celiac disease. Conversely, if the patient is IgA negative, there is only a 71% probability that the patient is truly negative for celiac disease. Therefore, a positive result is a strong indication that the patient has the disease but a negative result does not necessarily mean that they don not have it. False positive results are rather uncommon but false negative results can occur. On the other hand, the IgG anti-gliadin antibodies are 91% specific and have an 87% sensitivity. This means that they will show positive results more readily but there is not as strong a correlation with celiac disease. It is less specific. Patients with other conditions but not afflicted with celiac disease will occasionally show positive results. IgG anti-gliadin antibodies are detectable in approximately 21% of patients with other gastrointestinal disorders. This test might yield false positive results but is less likely to yield false negative results.

0

Share this post


Link to post
Share on other sites

Well, you can probably safely assume gluten intolerance at this point. Gluten is obviously making you feel sick. It's hard to say "celiac" for sure, because the IgG antibodies are less specific than the IgA ones, and without the EMA or TtG being positive, there is a chance your IgG elevation could be from another condition (see paragraph below). Still, you can see, there is a 91% chance it IS celiac.

Unfortunately, that leaves you in the boat of "maybe yes, maybe no". I've seen you wrestling with this on some other threads. If you are going to do more testing, you really need to make sure they do the total IgA along with everything else.

Gluten intolerance is a real condition, and can have a lot of negative effects on your life just like full-blown celiac; just without the flattened villi. Do you need a hard-copy celiac diagnosis for some reason?

Here's an explanation of the antibodies from an article on this site:

Anti-Gliadin Antibodies:

Both IgA and IgG anti-gliadin antibodies (AGA) are detected in sera of patients with gluten sensitive enteropathy (celiac disease). IgG anti-gliadin antibodies are more sensitive but are less specific markers for disease compared with IgA class antibodies. IgA anti-gliadin antibodies are less sensitive but are more specific. In clinical trials, the IgA antibodies have a specificity of 97% but the sensitivity is only 71%. That means that, if a patient is IgA positive, there is a 97% probability that they have celiac disease. Conversely, if the patient is IgA negative, there is only a 71% probability that the patient is truly negative for celiac disease. Therefore, a positive result is a strong indication that the patient has the disease but a negative result does not necessarily mean that they don not have it. False positive results are rather uncommon but false negative results can occur. On the other hand, the IgG anti-gliadin antibodies are 91% specific and have an 87% sensitivity. This means that they will show positive results more readily but there is not as strong a correlation with celiac disease. It is less specific. Patients with other conditions but not afflicted with celiac disease will occasionally show positive results. IgG anti-gliadin antibodies are detectable in approximately 21% of patients with other gastrointestinal disorders. This test might yield false positive results but is less likely to yield false negative results.

Thank you for the great response! I dont know IF there is a hard reason that I NEED to know. It would suck to be the 3% the is negative and eat gluten free ON ONE HAND. On the other hand I feel better off of gluten. Maybe I wonder if gluten intolerant can cause the same diseases? Maybe I am wanting someone to say my symptoms are something else. I honestly have no interest in going to the dr tomorrow. I kinda hope you would say yep you have it! And I would be done :)

0

Share this post


Link to post
Share on other sites
Ads by Google:


Thank you for the great response! I dont know IF there is a hard reason that I NEED to know. It would suck to be the 3% the is negative and eat gluten free ON ONE HAND. On the other hand I feel better off of gluten. Maybe I wonder if gluten intolerant can cause the same diseases? Maybe I am wanting someone to say my symptoms are something else. I honestly have no interest in going to the dr tomorrow. I kinda hope you would say yep you have it! And I would be done :)

I do hope that the new doctor is a little more intuitive and a little more curious than the one you've been working with! It is definitely unpleasant to be going through all this. It is expensive, and it is a huge hassle. On the other hand, getting health improvements is worth it!

It is extremely important to get that total serum IgA. Finding out that is insufficient would push this more in the direction of celiac. Here's another description of how the tests are used...might be a little more informational than the other one.

I sure wish, for your sake, this could be more cut and dried. Celiac diagnosis is just not all that exact for a lot of people. :huh:

Seeing the difference in yourself on and off gluten is a huge factor but I know what you mean about being the 3%. It was difficult for me to allow myself to think I had to be off gluten forever because I also have a weird test presentation (positive only on TtG Igg). I LOVE and ADORE sourdough bread. No gluten-free substitute for a good,crusty San Francisco sourdough! My doc made it a lot easier for me to get on the gluten-free path.

0

Share this post


Link to post
Share on other sites

One thing shalnuts; if you still intend to go to the doc & get tested again. You MUST be consuming & HAVE BEEN consuming gluten. You can not have been off gluten for even a week. Otherwise the tests get screwed up b/c of that.

0

Share this post


Link to post
Share on other sites

Most "gliadin IgG" these days is deamidated gliadin peptide, not the AGA Beachbirdie posted about. That is a very sensitive and specific test for celiac and it's the IgG that tends to be positive. If you know what lab ran the 2011 test you can call them and check what you got. If you have gliadin peptide IgG positive and feel awful on gluten I'd say you can consider yourself celiac.

0

Share this post


Link to post
Share on other sites

Skylark, here's the whole story:

http://www.celiac.com/gluten-free/topic/94090-lost-and-confused-so-sick-please-advise/page__p__804336__fromsearch__1#entry804336

She was dx'd celiac 9 years ago. Went gluten-free for 5 yrs. but still felt bad, went back to doc & doc said go back to gluten & take immodium. She's just had a series of BAD docs.

0

Share this post


Link to post
Share on other sites

Thanks for the rest of the story. Yeah, it sure sounds like celiac. Damn doctors. :blink:

0

Share this post


Link to post
Share on other sites

Really. It's like there's a secret society of them which is determined to not diagnose people. Pardon me, I wasn't skeletal and I had neuropathy and was falling over my own feet literally so therefore it just couldn't be that ! blah, blah, blah. <_<

To original poster. You were diagnosed, so stop eating the ****ed gluten ! None of us get to "100% normal" even if we eat perfectly, because we can be temporarily knocked down by cross contamination, or still have some other related diseases or conditions which we have to deal with, but most of us get to very high or at least acceptable functioning.

1

Share this post


Link to post
Share on other sites

Most "gliadin IgG" these days is deamidated gliadin peptide, not the AGA Beachbirdie posted about. That is a very sensitive and specific test for celiac and it's the IgG that tends to be positive. If you know what lab ran the 2011 test you can call them and check what you got. If you have gliadin peptide IgG positive and feel awful on gluten I'd say you can consider yourself celiac.

Not if you get it from my doctor's lab. :blink: It's why I asked for clarification.

She has been frustrated because she cannot get them to do the DGP. She's now going to be sending her celiac testing outside the local health conglomerate collective monopoly errr....system, even though people will likely have to drive 25 miles to get the tests.

0

Share this post


Link to post
Share on other sites

You know, I really wish people would keep their story in one thread. It's impossible to help someone with all the relevant info scattered about. :(

0

Share this post


Link to post
Share on other sites

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!


Register a new account

Sign in

Already have an account? Sign in here.


Sign In Now
0

  • Forum Statistics

    • Total Topics
      106,427
    • Total Posts
      930,502
  • Member Statistics

    • Total Members
      63,851
    • Most Online
      3,093

    Newest Member
    Daniellesmom
    Joined
  • Popular Now

  • Topics

  • Posts

    • Yeah we learned that the hard way.  I am inclined to think (as I did initially) that it was JUST the Cheerios but as time is passing and she is not bouncing back I am worried that we need to strip away dairy again for a while.
    • Oh I have no issue with being dairy free personally but tell that to a 13 year old.  We both went gluten-free at the same time and it has been mindlessly easy for me.  But I am easy about food and no real food issues.  I am far more adaptable.  She comes to the table with her own unique set of issues that complicate just easily transitioning to dairy free versions of much loved favorites.  To most they are jst that "substitutes" to her they are completely different foods and ones that she has no interest in eating.  They don't satisfy her need for XYZ.  It is like craving an apple and someone handing you a fish.  For her anyway! LOL!
    • I believe the talk around this forum is that cheerios are not gluten free enough for people with celiac at this time. I don't know if anything has changed on that and when their lawyer calls me I'll quickly delete this. haha  
    • Could be we generally say get off of dairy for a few months when going gluten free. The part of the intestines that produce the enzymes, and help break down dairy are associated with the tips of the villi, which are the most damaged if not gone in celiacs. THIS is why most of us end up with a lactose intolerance early on. And most can introduce it later after healing. As to her symptoms with it there was a bunch of research about dairy permeated the gut and causing neurological issues in a autism study I was looking at years ago. And there have been other studies about damaged intestines and how the hormones in milk can easier effect ones body.   Personally I also have a huge grudge against dairy on a personal level as it is not natural to suck on a cows tits and drink the stuff, nor your dogs, nor a rabbits......I mean come on even Human Breast milk you would find odd to drink as an adult right? Back in the past dairy was a great way to get calories and fats when there was famine, etc around I mean it is meant to make a calf grow into a 500+lb cow. But on a genetic and hormonal level it is not really for human consumption and now days the whole corporate BS propaganda push and dairy farms shove that oh its healthy stuff down your throat. There are plenty of dairy free options for everything feel free to message me if you need help finding anything I have been dairy free for over a decade.
    • The full celiac panel checks TTG IGA and IGG, DGP IGA and IGG, IGA, EMA as Jmg stated above. Your test included TTG IGA and IGA. If your IGA was low, a low on TTG IGA would be inconclusive. But your IGA is fine. A high on any one test is a positive for celiac and should lead to an endoscopy for confirmation. So I'd get tested for TTG IGG, DGP IGA and IGG and EMA since there are symptoms. Warning I'm not a doc.    
  • Upcoming Events