• Ads by Google:
     




    Get email alerts Celiac.com E-Newsletter

    Ads by Google:



       Get email alertsCeliac.com E-Newsletter

  • Announcements

    • admin

      Frequently Asked Questions About Celiac Disease   09/30/2015

      This Celiac.com FAQ on celiac disease will guide you to all of the basic information you will need to know about the disease, its diagnosis, testing methods, a gluten-free diet, etc.   Subscribe to FREE Celiac.com email alerts   What are the major symptoms of celiac disease? Celiac Disease Symptoms What testing is available for celiac disease? - list blood tests, endo with biopsy, genetic test and enterolab (not diagnostic) Celiac Disease Screening Interpretation of Celiac Disease Blood Test Results Can I be tested even though I am eating gluten free? How long must gluten be taken for the serological tests to be meaningful? The Gluten-Free Diet 101 - A Beginner's Guide to Going Gluten-Free Is celiac inherited? Should my children be tested? Ten Facts About Celiac Disease Genetic Testing Is there a link between celiac and other autoimmune diseases? Celiac Disease Research: Associated Diseases and Disorders Is there a list of gluten foods to avoid? Unsafe Gluten-Free Food List (Unsafe Ingredients) Is there a list of gluten free foods? Safe Gluten-Free Food List (Safe Ingredients) Gluten-Free Alcoholic Beverages Distilled Spirits (Grain Alcohols) and Vinegar: Are they Gluten-Free? Where does gluten hide? Additional Things to Beware of to Maintain a 100% Gluten-Free Diet What if my doctor won't listen to me? An Open Letter to Skeptical Health Care Practitioners Gluten-Free recipes: Gluten-Free Recipes Where can I buy gluten-free stuff? Support this site by shopping at The Celiac.com Store.

Only Igg High....am A Celiac?
0

13 posts in this topic

Was told I was not Celiac by my GI. I went back to gluten. I feel horrible. Nauseaus all day plus much more. I dug and found my old results. So do you think I have Celiac?

Found my old results (Oct/06)

Gliadin Antibody IGG 31 High Range <11

Gliadin Antibody IGA 6 Range <6

Reticulin igg ab <1:10 Range <1:10

Reticulin IGA AB <1:10 Range <1:10

Tissue Transglut. IGA <3 Range <5

Then found 03/07/11 Everything the same but Gliadin IgG 23.4 High Range <10

What does it mean that eveything is normal BUT the Gliadin IgG?

0

Share this post


Link to post
Share on other sites
Ads by Google:
Ads by Google:


Was told I was not Celiac by my GI. I went back to gluten. I feel horrible. Nauseaus all day plus much more. I dug and found my old results. So do you think I have Celiac?

Found my old results (Oct/06)

Gliadin Antibody IGG 31 High Range <11

Gliadin Antibody IGA 6 Range <6

Reticulin igg ab <1:10 Range <1:10

Reticulin IGA AB <1:10 Range <1:10

Tissue Transglut. IGA <3 Range <5

Then found 03/07/11 Everything the same but Gliadin IgG 23.4 High Range <10

What does it mean that eveything is normal BUT the Gliadin IgG?

Well, first of all, since they do not appear to have done a total serum IgA, none of the IgA results mean a thing. If your total IgA is insufficient, ALL your IgA tests will most likely be low.

Second, your body is making antibodies against gluten. Your body does not like gluten. Your doc is a twit who should have done further testing. Especially considering you feel sick while eating gluten!

We can't answer the question definitively because we are not doctors, but there is an extremely high likelihood that yes, in spite of what your doctor said, you might have celiac.

Is there anything on your lab report that indicates whether the gliadin antibodies are "deamidated gliadin peptides"? Those are newer and more sensitive/specific than the old AGA (anti-gliadin antibody) tests. If your test was DGP, the likelihood is even higher for celiac.

0

Share this post


Link to post
Share on other sites

Thank you. I am going to a new Dr tomorrow.

Nothing else on the test results. I plan to get retested IF my insurance will cover it. Last visit the dr only used promethius and my insurance wouldnt pay. They said it would be about $1000!

Can I assume that with high IGG I am gluten intolerant? Not necessarily celiac?

0

Share this post


Link to post
Share on other sites

Thank you. I am going to a new Dr tomorrow.

Nothing else on the test results. I plan to get retested IF my insurance will cover it. Last visit the dr only used promethius and my insurance wouldnt pay. They said it would be about $1000!

Can I assume that with high IGG I am gluten intolerant? Not necessarily celiac?

Well, you can probably safely assume gluten intolerance at this point. Gluten is obviously making you feel sick. It's hard to say "celiac" for sure, because the IgG antibodies are less specific than the IgA ones, and without the EMA or TtG being positive, there is a chance your IgG elevation could be from another condition (see paragraph below). Still, you can see, there is a 91% chance it IS celiac.

Unfortunately, that leaves you in the boat of "maybe yes, maybe no". I've seen you wrestling with this on some other threads. If you are going to do more testing, you really need to make sure they do the total IgA along with everything else.

Gluten intolerance is a real condition, and can have a lot of negative effects on your life just like full-blown celiac; just without the flattened villi. Do you need a hard-copy celiac diagnosis for some reason?

Here's an explanation of the antibodies from an article on this site:

Anti-Gliadin Antibodies:

Both IgA and IgG anti-gliadin antibodies (AGA) are detected in sera of patients with gluten sensitive enteropathy (celiac disease). IgG anti-gliadin antibodies are more sensitive but are less specific markers for disease compared with IgA class antibodies. IgA anti-gliadin antibodies are less sensitive but are more specific. In clinical trials, the IgA antibodies have a specificity of 97% but the sensitivity is only 71%. That means that, if a patient is IgA positive, there is a 97% probability that they have celiac disease. Conversely, if the patient is IgA negative, there is only a 71% probability that the patient is truly negative for celiac disease. Therefore, a positive result is a strong indication that the patient has the disease but a negative result does not necessarily mean that they don not have it. False positive results are rather uncommon but false negative results can occur. On the other hand, the IgG anti-gliadin antibodies are 91% specific and have an 87% sensitivity. This means that they will show positive results more readily but there is not as strong a correlation with celiac disease. It is less specific. Patients with other conditions but not afflicted with celiac disease will occasionally show positive results. IgG anti-gliadin antibodies are detectable in approximately 21% of patients with other gastrointestinal disorders. This test might yield false positive results but is less likely to yield false negative results.

0

Share this post


Link to post
Share on other sites

Well, you can probably safely assume gluten intolerance at this point. Gluten is obviously making you feel sick. It's hard to say "celiac" for sure, because the IgG antibodies are less specific than the IgA ones, and without the EMA or TtG being positive, there is a chance your IgG elevation could be from another condition (see paragraph below). Still, you can see, there is a 91% chance it IS celiac.

Unfortunately, that leaves you in the boat of "maybe yes, maybe no". I've seen you wrestling with this on some other threads. If you are going to do more testing, you really need to make sure they do the total IgA along with everything else.

Gluten intolerance is a real condition, and can have a lot of negative effects on your life just like full-blown celiac; just without the flattened villi. Do you need a hard-copy celiac diagnosis for some reason?

Here's an explanation of the antibodies from an article on this site:

Anti-Gliadin Antibodies:

Both IgA and IgG anti-gliadin antibodies (AGA) are detected in sera of patients with gluten sensitive enteropathy (celiac disease). IgG anti-gliadin antibodies are more sensitive but are less specific markers for disease compared with IgA class antibodies. IgA anti-gliadin antibodies are less sensitive but are more specific. In clinical trials, the IgA antibodies have a specificity of 97% but the sensitivity is only 71%. That means that, if a patient is IgA positive, there is a 97% probability that they have celiac disease. Conversely, if the patient is IgA negative, there is only a 71% probability that the patient is truly negative for celiac disease. Therefore, a positive result is a strong indication that the patient has the disease but a negative result does not necessarily mean that they don not have it. False positive results are rather uncommon but false negative results can occur. On the other hand, the IgG anti-gliadin antibodies are 91% specific and have an 87% sensitivity. This means that they will show positive results more readily but there is not as strong a correlation with celiac disease. It is less specific. Patients with other conditions but not afflicted with celiac disease will occasionally show positive results. IgG anti-gliadin antibodies are detectable in approximately 21% of patients with other gastrointestinal disorders. This test might yield false positive results but is less likely to yield false negative results.

Thank you for the great response! I dont know IF there is a hard reason that I NEED to know. It would suck to be the 3% the is negative and eat gluten free ON ONE HAND. On the other hand I feel better off of gluten. Maybe I wonder if gluten intolerant can cause the same diseases? Maybe I am wanting someone to say my symptoms are something else. I honestly have no interest in going to the dr tomorrow. I kinda hope you would say yep you have it! And I would be done :)

0

Share this post


Link to post
Share on other sites
Ads by Google:


Thank you for the great response! I dont know IF there is a hard reason that I NEED to know. It would suck to be the 3% the is negative and eat gluten free ON ONE HAND. On the other hand I feel better off of gluten. Maybe I wonder if gluten intolerant can cause the same diseases? Maybe I am wanting someone to say my symptoms are something else. I honestly have no interest in going to the dr tomorrow. I kinda hope you would say yep you have it! And I would be done :)

I do hope that the new doctor is a little more intuitive and a little more curious than the one you've been working with! It is definitely unpleasant to be going through all this. It is expensive, and it is a huge hassle. On the other hand, getting health improvements is worth it!

It is extremely important to get that total serum IgA. Finding out that is insufficient would push this more in the direction of celiac. Here's another description of how the tests are used...might be a little more informational than the other one.

I sure wish, for your sake, this could be more cut and dried. Celiac diagnosis is just not all that exact for a lot of people. :huh:

Seeing the difference in yourself on and off gluten is a huge factor but I know what you mean about being the 3%. It was difficult for me to allow myself to think I had to be off gluten forever because I also have a weird test presentation (positive only on TtG Igg). I LOVE and ADORE sourdough bread. No gluten-free substitute for a good,crusty San Francisco sourdough! My doc made it a lot easier for me to get on the gluten-free path.

0

Share this post


Link to post
Share on other sites

One thing shalnuts; if you still intend to go to the doc & get tested again. You MUST be consuming & HAVE BEEN consuming gluten. You can not have been off gluten for even a week. Otherwise the tests get screwed up b/c of that.

0

Share this post


Link to post
Share on other sites




Most "gliadin IgG" these days is deamidated gliadin peptide, not the AGA Beachbirdie posted about. That is a very sensitive and specific test for celiac and it's the IgG that tends to be positive. If you know what lab ran the 2011 test you can call them and check what you got. If you have gliadin peptide IgG positive and feel awful on gluten I'd say you can consider yourself celiac.

0

Share this post


Link to post
Share on other sites

Skylark, here's the whole story:

http://www.celiac.com/gluten-free/topic/94090-lost-and-confused-so-sick-please-advise/page__p__804336__fromsearch__1#entry804336

She was dx'd celiac 9 years ago. Went gluten-free for 5 yrs. but still felt bad, went back to doc & doc said go back to gluten & take immodium. She's just had a series of BAD docs.

0

Share this post


Link to post
Share on other sites

Thanks for the rest of the story. Yeah, it sure sounds like celiac. Damn doctors. :blink:

0

Share this post


Link to post
Share on other sites




Really. It's like there's a secret society of them which is determined to not diagnose people. Pardon me, I wasn't skeletal and I had neuropathy and was falling over my own feet literally so therefore it just couldn't be that ! blah, blah, blah. <_<

To original poster. You were diagnosed, so stop eating the ****ed gluten ! None of us get to "100% normal" even if we eat perfectly, because we can be temporarily knocked down by cross contamination, or still have some other related diseases or conditions which we have to deal with, but most of us get to very high or at least acceptable functioning.

1

Share this post


Link to post
Share on other sites

Most "gliadin IgG" these days is deamidated gliadin peptide, not the AGA Beachbirdie posted about. That is a very sensitive and specific test for celiac and it's the IgG that tends to be positive. If you know what lab ran the 2011 test you can call them and check what you got. If you have gliadin peptide IgG positive and feel awful on gluten I'd say you can consider yourself celiac.

Not if you get it from my doctor's lab. :blink: It's why I asked for clarification.

She has been frustrated because she cannot get them to do the DGP. She's now going to be sending her celiac testing outside the local health conglomerate collective monopoly errr....system, even though people will likely have to drive 25 miles to get the tests.

0

Share this post


Link to post
Share on other sites

You know, I really wish people would keep their story in one thread. It's impossible to help someone with all the relevant info scattered about. :(

0

Share this post


Link to post
Share on other sites

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!


Register a new account

Sign in

Already have an account? Sign in here.


Sign In Now
0

  • Forum Statistics

    • Total Topics
      107,389
    • Total Posts
      935,830
  • Member Statistics

    • Total Members
      65,076
    • Most Online
      3,093

    Newest Member
    MayonnaisePlease
    Joined
  • Popular Now

  • Topics

  • Posts

    • Hello thankyou its always great to know that other people are going through things the same time. Yes my endoscopy is friday coming at 8.15am, been through the procedure before for diagnosing a hernia so that side of things are ok, just not sure if i needed the biopsy at first being the blood test confirmed  positive but i know now that i do need it not just for me but also for my 11 year old daughter who could also be celiac later and it would be better for her to know 100% mum is celiac.
    • Hi Whitepaw Your question about what was I eating before I fell ill is a good one.  I had given a party the previous month and there was a lot of cake left over and what is more, it was all gluten free because I had made it!  So I was eating maybe a couple of slices a day...  I was taking soluable aspirin when I shouldn't take it, really.  I was also taking iron supplements.   And adding chilli to a lot of my food - normally not a problem.   And I had a huge amount of stress going on having just completed a project and also having tests on a lump on my tongue. Oh yes - and  I ate some marshmallows which may have contained gluten?  And my son had a stomach virus at the time. High fat food + aspirin + iron supplements + chilli + stress+ possible glutening + stomach virus?  = gastritis!! I also ate quite a lot of walnuts the days before it got really bad so maybe they didn't help. I need to be much more careful - it has taught me a lesson. I'm particularly cross with myself about the aspirin and also not checking the marshmallow ingredients as I am usually so careful. I know exactly what you mean about dreading the next meal - last night I had chicken and potato again but added a tiny bit of bolognese and I actually enjoyed the meal, which I think meant it sat easier in my stomach.   I think that there is a psychological element to acute gastritis, too.  I think if one is stressed it can hang around a lot longer.  I have read a few posts from people who found after trying to do all the right things to get better it was going onto medication to help with stress that actually helped them get better in the end.  I can see that - because if I could hear the children fighting, or had a stressful conversation with someone, I could actually feel my stomach react. Anyway - thank you for your help, I am so grateful. And great idea about the food diary.  Perhaps, also, worth making a note about stress factors on a particular day, and what meds one was on.  I think ompremazole was a great way to stop the gnawing pain for me but since I have lowered the dose I have to say that a lot of the bloating and feeling of nausea has gone. I think if I ever get gastritis again I'll stick myself on a gastritis diet first, just for a few days.   If that doesn't help I'll probably check with my doctor but take ompremazole for maybe two to three weeks til the gnawing stops, then taper down.  I hope it won't happen again though!  There is no doubt about it, it is a drug to be taken with caution, but I have to say I have heard some success stories too of people who took it short term and were helped tremendously.  I think tapering off it is probably a good idea, though, because I do have a friend who I think is suffering from rebound at the moment by coming off an inhibitor cold turkey.
    • Hey all so ever since about a week ago I felt a sharp pain in my upper right quadrant, followed by a minor hotflash and it hurts to press on my right side. I'm extremely worried because I was admitted to the ER last night, blood came back fine, xray fine and ultrasound fine. What prompted me to enter the ER was the fact that now my breathing is affected..   SYMPTOMS SO FAR: Sharp Pain Touching My Right Side Minor weakness , no fever. Mucus in stools? (when i wipe its a yellow on the toilet paper sorry for tmi) Right shoulder soreness Mucus in jugular? Or lung!? The "pipe" you can feel on your neck going up to your head, somewhat warm to the touch. Aches to touch. Happens mostly at night. Began last night and returned tonight. Unusually smelly breath. Awful Constipation, when I CAN go barely anything comes out as its flaky. Slight Pain in right leg, comes and goes. Very active stomach, gurgling can be heard from as high up as my chest. Slight stomach pain relief when massaging. I'm very worried people I'm petrified of surgery and I don't want to die.. But I don't understand why everything would come clean if im experiecing these symptoms?   Anyways
    • Well thanks everyone seriously. I'm sure this will get better and I'm thankful this reaction is normal. So guilty when I think of others worse off than me. I will read and read and read until I've taught myself to feel better. And then help others ((((hugs all around)))
    • I'm curious to hear updates on your EC condition.   Thanks
  • Upcoming Events