• Join our community!

    Do you have questions about celiac disease or the gluten-free diet?

  • Ads by Google:

    Get email alerts Subscribe to Celiac.com's FREE weekly eNewsletter

    Ads by Google:

       Get email alertsSubscribe to Celiac.com's FREE weekly eNewsletter

  • Announcements

    • admin

      Frequently Asked Questions About Celiac Disease   09/30/2015

      This Celiac.com FAQ on celiac disease will guide you to all of the basic information you will need to know about the disease, its diagnosis, testing methods, a gluten-free diet, etc.   Subscribe to Celiac.com's FREE weekly eNewsletter   What are the major symptoms of celiac disease? Celiac Disease Symptoms What testing is available for celiac disease?  Celiac Disease Screening Interpretation of Celiac Disease Blood Test Results Can I be tested even though I am eating gluten free? How long must gluten be taken for the serological tests to be meaningful? The Gluten-Free Diet 101 - A Beginner's Guide to Going Gluten-Free Is celiac inherited? Should my children be tested? Ten Facts About Celiac Disease Genetic Testing Is there a link between celiac and other autoimmune diseases? Celiac Disease Research: Associated Diseases and Disorders Is there a list of gluten foods to avoid? Unsafe Gluten-Free Food List (Unsafe Ingredients) Is there a list of gluten free foods? Safe Gluten-Free Food List (Safe Ingredients) Gluten-Free Alcoholic Beverages Distilled Spirits (Grain Alcohols) and Vinegar: Are they Gluten-Free? Where does gluten hide? Additional Things to Beware of to Maintain a 100% Gluten-Free Diet What if my doctor won't listen to me? An Open Letter to Skeptical Health Care Practitioners Gluten-Free recipes: Gluten-Free Recipes

New Here With Test Results

Rate this topic

Recommended Posts


I went for a consult for my fist colonoscopy. The GI doctor noticed I had marked Hashimotos Thryroiditis on my health questionnaire. He suggested I test for Celiac since often Hashimotos and Celiac go "hand in hand."

Test results are back:

TT Ab IgA normal 1.2 (<4)

TT Ab IgG positive 18 (>9 positive)

Gliadin IgA normal 3.1 ( < 20)

Gliadin IgG normal 3.1 (< 20)

IgA 132 normal (71-397)

The only positive is the TT Ab IgG. He is recommending a biopsy to confirm the results. I'm thinking I should go ahead and do it, if nothing else then to spare my close relatives and kids the need to be tested for Celiac. Could the Hashimotos throw off the results? Do these results look typical of Celiac? Any help or advice would be appreciated.

(I do not have obvious GI problems so this has been a surprise....)


Share this post

Link to post
Share on other sites
Ads by Google:
Ads by Google:

I have Hashimoto's and will be tested for celiac soon... Hope you get some answers!

Share this post

Link to post
Share on other sites

No, the Hashimoto's would not affect the results which are measuring antibodies to gluten in the bloodwork, and damage to the small intestine when they do the biopsy.

There is no "typical" set of celiac results. It is only necessary to be positive on one of the tests. Yours is a little unusual in that you tested positive on the IgG tissue transglutaminase and negative on the IgA, but yet you make normal quantities of IgA. Normally they run the IgG only if you make insufficient quantities of IgA, but your IgA was normal. I note that they did not run the newer, and more specific for celiac, DGP (deamidated gliadin peptide) which is often run in both IgA and IgG versions.

At any rate, the biopsy is often useful to make sure that everything else is normal in the upper intestinal tract and to check the level of damage. Sometimes the bloods are positive and the EGD negative. If this happens with you, don't let the doctor tell you that you don't have celiac, because it is often missed. Make sure he takes at least 6-8 samples because the damage can be patchy and easily missed. You can start the gluten free diet immediately after the biopsy, so now is a good time to start going through your pantry for foods to donate to a food pantry, and to start thinking about preparing your food gluten free. There is a lot of good reading on this site, beginning with Newbie 101, and plenty of threads on how to deglutenize, lots of recipes, etc. Happy reading, and best wishes for your EGD if you decide to go ahead with it. :)

Welcome to the board, and ask as many questions as you want.

Share this post

Link to post
Share on other sites

Thank you mushroom. I am definitely reading a lot about going gluten free and getting set-up to give it a try.

Edited by lizcon

Share this post

Link to post
Share on other sites

I think it is different for each person. My son had normal IgA tests and was only positive on the IgG tests. He had ZERO GI symptoms. Our only clue something was wrong was a drastic change in behavior. He didn't even complain of feeling bad, he just turned in to the devil. (age 5). His biopsy was very positive.

My blood tests were the opposite. Only my IgA tests were positive. I had all the classic GI symptoms for about 5 years (maybe triggered by my pregnancy?). When I had the endoscopy, it came back negative.

We both went gluten free and it has made a world of difference. The other two in the family seem to tolerate gluten just fine, but I do have my older son checked every couple of years to make sure.

After you complete the tests, try the diet REGARDLESS of the results.

Good luck -


Share this post

Link to post
Share on other sites
Ads by Google:

Yes the TTG can be falsely positive in Hashimoto's. Before some member asks "What does a false positive really mean?" or "There are no false positives"

A false positive means that in clinical evaluation members of a certain population sample with an elevated TTG did not actually have celiac upon further testing and never went on to develop it during clinical follow up years and even decades later. YES there are absolutely false positive in antibody tests, the endomysial is interpreting a staining pattern on monkey oesophagus, the whole point is that celiac blood tests are highly unreliable unless all very strongly positive (10 times the normal range). Your test is a very low number and is typical in the false positive range, do the biopsy and report back to us what happens.


What’s the problem with diagnosing celiac disease simply by measuring the decrease in antibodies once someone switches to a gluten-free diet?

The con is that you’ll never know if a patient truly has celiac disease versus other causes for elevated antibodies. tTG are thought to be 97-98% specific, but by definition this means that 3 in 100 persons who don’t have celiac disease will have elevated tTG (biological variations, nothing more). If you consider that celiacs are 1% of the general population, it follows that out of 100 persons tested for tTG: 1 has celiac disease and 3 do not. This could mean that only 1 out of 4 of those with positive antibodies will have celiac disease as the cause. This is why you need a biopsy to confirm it.


Share this post

Link to post
Share on other sites

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now


  • Forum Statistics

    • Total Topics
    • Total Posts
  • Member Statistics

    • Total Members
    • Most Online

    Newest Member
  • Popular Now

  • Topics

  • Posts

    • I’m 62 and have just now been tested for Celiac.  My Titer was negative, I have zero IGa and too much IGg (16) which is an indicator of intolerance at the very least and may indicate the need for another endoscopy. He also tested for EPI (exocrine pancreatic insufficiency) which was negative.  I just had a colonoscopy/endoscopy last year as a part of being diagnosed w/ Gastroparesis. I also have (among other things which I’m not sure are as relevant) - T2 Diabetes, Hashimotos Thyroiditis (late 30’s) Chronic Kidney Stones (since age 40), Osteoporosis (way before Menopause and not well controlled), and Gallbladder disease.(was removed) I’m discovering that all those I listed may be related in some way, and related to Celiac.  I haven’t seen the gastro doc for followup since the testing (obtained results from lab) so I’m not sure what he’s going to recommend.  Here’s where it gets scary... my daughter has many of the same things. She was just diagnosed with EDS (Ehlers-Danlos Syndrome) at 32.  She was diagnosed w/Glucose intolerance at 15, had her Gallbladder removed at 20, PCOS at 22, and Gluten intolerance at 30 (no testing, just her gastro’s recommendation). She’s been diagnosed w/Gastroparesis, POTS,  MAST Cell Activation Disorder, Peripheral Neuropathy, (lost use of her bladder and has a neuro stimulator) - all in the last year.  Too much coincidence for me.  This has to be all related. I keep reading more and more studies linking all these things (like EDS and Celiac) together. My daughters  geneticist is blown away by the multiple overlapping and co-morbid conditions we have and tells us it’s not uncommon. She also says research is expanding.  Sadly, the specialist docs seem baffled and can’t even begin to address our issues, and only help to manage the symptoms - sometimes. And every “Disease/Disorder” has a “diet” or protocol, and they are all at odds with each other - very frustrating.  I guess the moral of this story is to let others know that there’s a lot more to all this than meets the eye. Don’t let anyone tell you you’re fine if you have what seem to be strange unrelated symptoms. You’re not crazy. Keep fighting for understanding and knowledge. Be an advocate for yourself, you’re loved ones,  for us all.      
    • Nice to know that Disney makes an effort to take care of people with allergies or special diets (like gluten free!): https://publicaffairs.disneyland.com/walt-disney-parks-resorts-receives-honors-allergy-friendly-fare/
    • Wow, I also had pyloric stenosis that was misdiagnosed for some weeks as an infant (and almost died from it).  I also have Raynauld’s and I started following celiac diet, finding an immediate improvement of my symptoms.  I thought I was the only one that had all 3 of these diagnoses.   Interesting.
    • If you are lucky enough to travel in the Spanish-speaking world, just about anywhere you go, you will very likely run into a some version of chicken and rice, or ‘Arroz con Pollo’ as it appears on countless menus. This Cuban-style version relies on annatto oil to give it a red color. You can make your own annatto oil by putting achiote chili seeds in vegetable oil and heating it up for a few minutes over the stove. Cool and store. This version of chicken and rice is tasty, gluten-free and keeps well in the freezer. View the full article
    • I was diagnosed with celiac at the end of October. My DGP IgA was tested September 12th and was 127. I just got it retested and it was 135. I have been eating gluten free since I was diagnosed. I thought the numbers should be going down. How long does it usually take for the numbers to start dropping? Right now I feel like I must be getting cross contamination somewhere.
  • Upcoming Events