• Join our community!

    Do you have questions about celiac disease or the gluten-free diet?

  • Ads by Google:
     




    Get email alerts Subscribe to Celiac.com's FREE weekly eNewsletter

    Ads by Google:



       Get email alertsSubscribe to Celiac.com's FREE weekly eNewsletter

  • Announcements

    • admin

      Frequently Asked Questions About Celiac Disease   09/30/2015

      This Celiac.com FAQ on celiac disease will guide you to all of the basic information you will need to know about the disease, its diagnosis, testing methods, a gluten-free diet, etc.   Subscribe to Celiac.com's FREE weekly eNewsletter   What are the major symptoms of celiac disease? Celiac Disease Symptoms What testing is available for celiac disease?  Celiac Disease Screening Interpretation of Celiac Disease Blood Test Results Can I be tested even though I am eating gluten free? How long must gluten be taken for the serological tests to be meaningful? The Gluten-Free Diet 101 - A Beginner's Guide to Going Gluten-Free Is celiac inherited? Should my children be tested? Ten Facts About Celiac Disease Genetic Testing Is there a link between celiac and other autoimmune diseases? Celiac Disease Research: Associated Diseases and Disorders Is there a list of gluten foods to avoid? Unsafe Gluten-Free Food List (Unsafe Ingredients) Is there a list of gluten free foods? Safe Gluten-Free Food List (Safe Ingredients) Gluten-Free Alcoholic Beverages Distilled Spirits (Grain Alcohols) and Vinegar: Are they Gluten-Free? Where does gluten hide? Additional Things to Beware of to Maintain a 100% Gluten-Free Diet What if my doctor won't listen to me? An Open Letter to Skeptical Health Care Practitioners Gluten-Free recipes: Gluten-Free Recipes

Rate this topic

Recommended Posts

Morning All,

While using my limited Google-Fu skills to find a way of deciphering the results of my Enterolab stool testing, I saw several results pointing me to this forum. While I consider myself a reasonable intelligent person, this seems sort of Greek to me so, I thought I'd try to ask someone who might be more of a 'subject matter expert'. If I'm reading this correctly, I do not really have Celiac disease but, I do have sensitivity to both gluten and eggs (the later completely threw me for a loop!) - am I correct in my understanding?

I also don't know if I really understand the genetic results but, again, sounds like I do not have the genes for Celiac but, do have two genes which indicate a predisposition to gluten sensitivity, does that sound right? Any input or guidance would be greatly appreciated. I'd like to be able to explain this to my other half who's pretty much said he won't be changing the way he cooks, with regard to the elimination of gluten, until I can show him there's a legitimate reason why he should (e.g., results showing that I have a sensitivity to wheat products).

Thanks in advance for your time and information!

Best,

C.

Edit - Realized I never included the actual results....

B) Gluten/Antigenic Food Sensitivity Stool/Gene Panel

Fecal Anti-gliadin IgA 13 Units (Normal Range is less than 10 Units)

Fecal Anti-casein (cow’s milk) IgA 7 Units (Normal Range is less than 10 Units)

Fecal Anti-ovalbumin (chicken egg) IgA 13 Units (Normal Range is less than 10 Units)

Fecal Anti-soy IgA 4 Units (Normal Range is less than 10 Units)

HLA-DQB1 Molecular analysis, Allele 1 0301

HLA-DQB1 Molecular analysis, Allele 2 0609

Serologic equivalent: HLA-DQ 3,1 (Subtype 7,6)

I wasn't sure if the narrative bits were also important to include but if so, please let me know and I'll happily update the information.

Edited by cwredden

Share this post


Link to post
Share on other sites
Ads by Google:
Ads by Google:


Curious....why didn't you go to a doctor and get a blood test? from what I have seen with Enterolabs, everyone gets a positive result. :).

I don't believe scientists have identified any genes for gluten sensitivity as that is a fairly new area of study.

Also read this link and the link T the bottom of it:

http://www.cureceliacdisease.org/archives/faq/why-dont-you-recognize-tests-stool-tests-or-otherwise-for-gluten-sensitivity-that-are-currently-available-through-companies-like-enterolab-or-cyrex

"Why don’t you recognize tests (stool tests or otherwise) for non-celiac gluten sensitivity that are currently available through companies like Enterolab or Cyrex?

We only embrace tests that have endured rigorous scientific evaluations. So far, these tests have received no evidence-based support.

Enterolab has never successfully published anything on the accuracy of stool tests (nor have any other stool test manufacturers, to our knowledge) making it difficult to confirm the research results. Because of this, we must make our decisions based on what has been published; Harvard, UCSD, and the American College of Gastroenterology all agree that stool tests are simply not sensitive or specific enough methods in screening for celiac disease.

Further reading: “Detection of secretory IgA antibodies against gliadin and human tissue transglutaminase in stool to screen for coeliac disease in children: validation study” at BMJ.com"

Share this post


Link to post
Share on other sites

Curious....why didn't you go to a doctor and get a blood test? from what I have seen with Enterolabs, everyone gets a positive result. :).

Primarily because from searching around the internet, it sounded as though blood tests were not as reliable (a link from an article on this site) and in my mind it did seem reasonable that if there was an issue with something related to the antibodies in the digestive tract, it made more sense to look there before those made their way into the blood stream. In my case, I don't think the test showed a positive for Celiac, which I'm quite happy about. With regard to everyone getting a positive result from Enterolab, I think a reasonable answer might be that individuals who have symptoms which align with gluten intolerance/sensitivity are the ones requesting the test. Could there be false positives? Possible. From my readings, I've seen a lot of information about false negatives from blood tests as well.

If the results from the stool testing had indicated Celiac then my next step would have been to move to the blood testing and/or the biopsy testing.

Share this post


Link to post
Share on other sites

Updated....realized I didn't actually include the information from the test.... :wacko:

Share this post


Link to post
Share on other sites

The only test you did that tests for celiac (as far as I can tell) is your anti-gliadin IgA whish is positive at 13. As you said, your next step is to try blood testing. The most common tests are:

ttg IgA and IgG

EMA IgA

total serum IgA

DGP IgA and IgG

I'm not sure how accurate the enterolab tests are (did not do them) but I have heard they tend to have a LOT of positives. The blood work done in your typical lab will err the other way: they have approximately a 25% false positive rate, but biopsies seem to catch those who appear to have normal blood.

I don't know anything about the DNA testing. I tested positive on blood work so I never bothered learning about the DNA tests since it's a moot point for me.

Good luck with your future testing if you choose to go tha direction. I hope you feel well soon.

Share this post


Link to post
Share on other sites
Ads by Google:


I do believe that the blood testing has a 25% false negative rate. There are very very few false positives on blood work. :-)

It looks like you have DQ7 and DQ6. Currently, DQ7 is not recognized as a celiac gene but there is some research starting to come out which points otherwise, especially in the case of no DQ2 or DQ8.

Laura

Share this post


Link to post
Share on other sites

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now

0

  • Forum Statistics

    • Total Topics
      108,923
    • Total Posts
      943,524
  • Member Statistics

    • Total Members
      67,134
    • Most Online
      3,093

    Newest Member
    SherriMT
    Joined
  • Popular Now

  • Topics

  • Posts

    • Almost 2 years into my diagnosis after losing about 35-40 pounds I have now added about 60 with clean gluten free eating. I also changed jobs which for me has been much more of a physical change, thus needing more calories I have finally been able to put back some pounds. It is possible, for me the clean diet which helped restore my guts let me finally start absorbing the nutrients I was lacking. 
    • Hi Niza, Try to eat lots of protein.  Meats, peanut butter, avocadoes, things like that.  Try to avoid processed (pre-made) foods like frozen pizza, cereals, pot pies, cookies etc.   There gluten-free versions of many of these foods, but they are best saved for later on like 6 months after going gluten-free. If you are just starting out gluten-free, eat a simple diet of mostly foods you make yourself at home.  Also, try not eat eating any dairy (milk, cheese etc) for a couple months.  Oats are also a thing to avoid eating for a couple months.  You may not have any problem with dairy or oats, but some people do. Welcome to the forum Niza!
    • I am. I went undiagnosed for years and years and I honestly thought I was dying. I had been trying to gain weight even before my diagnosis and could barely gain a thing. I am so relieved to actually have an answer as to WHY! I was just diagnosed last weekend so I still have a lot of internal healing to do after years of villus atrophy. I have been drastically underweight for some time now, although I am slowly gaining. I am currently eating around 2,500 calories a day and not doing any strenuous exercise. I am only 74 lb (at 5'2") and I started out at 67 back in the beginning of December. I eat as much as some of my guy friends eat in order to "bulk" when they are lifting heavy at the gym and yet I still seem to gain at a slower rate. Just goes to show how messed up your intestines can become after years of abuse. 
    • Hey Deb, In theory (based on some studies), your small instestine should heal pretty fast (within weeks), but often there is collateral damage that can take longer (like your bone pain).  For me, personally, a gluten exposure can set me back three to six months.  My antibodies can last over a year.  And worse, I now developed autoimmune gastritis and hives.  Yikes!   I had  some hip and rib cage pain when I was first diagnosed.  Two months later I fractured some vertebrae.  I had been undiagnosed for so long, that I developed osteoporosis.  I assume that once on a gluten free diet, your pain should diminish based on a strict adherence to the diet and  your previous experience.   I hope you feel better soon!  
    • I know-pretty dumb. I'm usually very careful. I didn't check into it. Thanks for reply. DebLee
  • Upcoming Events