Is It Possible To Have More Mood Symptoms? in Celiac Disease Pre-Diagnosis, Testing & Symptoms Posted November 11, 2006 · Report to Admin I take Enterolab with a grain of salt, honestly, but I was positive on that and negative on my blood test and the only thing I know for sure is how sick I get immediately after eating gluten. (Too sick to even go on a gluten challenge in order to get a biopsy). My symptoms are mostly physical, however, I get MAJOR ANXIETY when I eat gluten. Usually right afterwards. I also have been less depressed since I went gluten-free. Yeah, I don't know for sure exactly what's really going on... but I've been reading some very good books, and one, "Going Against the Grain" (Melissa Smith) says that NOBODY should really be eating gluten. Human beings have only been eating it for the past 10,000 years. We really didn't evolve to digest it. (Or if someone doesn't believe in evolution, Adam and Eve didn't eat it in the garden, you know. So it's possible to have sensitivity to it without anything showing up on a test (according to her theories, anyway.) I'm thinking about doing a very strict diet for a month, and then re-introducing things. At the absolute least, it can't hurt!