Dr. Kenneth Fine (enterolab) in Doctors Posted October 24, 2009 · Report to Admin Goodness . . . Yes, there IS a difference between gluten sensitivity and Celiac disease. I was gluten sensitive for many years -- diagnosed as "irritable bowel syndrome" and at one point, "ulcerative colitis". It wasn't until I encountered a tick that decided I looked somewhat like a delicacy and developed Lyme and three other tick-borne diseases that I subsequently began developing autoimmune diseases. I have a rather long list of them, but in the process of all of this, I sero-converted from "gluten sensitivity" to true Celiac Disease. My intestinal villi? Very healthy. I have Neurogenic Celiac. There is one protein on the Purkinje cell of the cerebellum that so strongly mimics gliadin that when your antigliadin antibodies are high - and you have sero-converted - it destroys those proteins. In the process, it also destroys your cerebellum's ability to maintain smooth transmission. It is also known as "Sprue-Related Ataxia" and "Neurological Celiac Disease" among others. Bottom line? I walk like a stumbling drunk. (Your cerebellum is what is affected most when you consume too much alcohol) I use a wheelchair for long outings, and I have a specially designed, weighted walker that I have just been able to get in order to try to walk without falling as much. The damage is permanent. No healing, no second chance. My son has developed two unusual autonomic manifestations recently. One is affecting his gut's inability to initiate peristalsis. Both are due to parasympathetic nervous system dysfunction -- routed through the cerebellum. He is 27 years old. He lives in Houston, TX. Because he disclosed my neurogenic celiac, he is having a full panel done. The MD understands that Celiac can manifest itself solely with neurological symptoms. My granddaughter is 14 months old and is very sensitive to many things. At this point, my daughter is keeping her on a gluten-restricted, but not gluten-free diet. She is actually doing more "challenges" to determine if gluten is one of the causes of the difficulty. If she finds that is the case, my daughter's family will live a gluten-free lifestyle and she will ensure that Sarah not consume gluten. If I knew then what I know now, the very minute that the neurologist said that I may have "Sprue-Related Ataxia", I would have gone on a strict gluten-free diet. Unfortunately, I waited almost eight months. The damage that was done to my cerebellum in that time, as I stated, is irreversible. You can see the changes chronologically when you look at my MRI studies. Then again, hindsight is 20/20. Enterolab or no, if your body has a negative reaction to gluten -- even with challenges -- it is trying to tell you something extremely important. I wish I had listened.