What And How Do You React To Foods? in Food Intolerance & Leaky Gut Posted August 12, 2010 · Report to Admin I totally hear you and I'm in the same boat. Today I had a bit of a breakthrough that may be of some help to you as I noticed we tend to react the same things. The allergy doc who works with my GI doc took blood to test IgE reactions to a number of foods (RAST). I was positive to 2 foods, neither of which I've eaten in a year, oats & rye. What he also noticed was that my blood work showed an unusually high level of histamine in my body. Previous bloodwork showed really high EOS (Eosinophils) which means I'm having some type of allergy reaction. He took more blood today to see if it's still high. If so I may have too much histamine in my body, a.k.a. a histamine intolerance. I never knew such thing existed. I've been treated for SIBO and I have been following the FODMAP diet (suspected fructmal but test was neg) and while I see some improvements I still feel like crap and have constant D. Even my bland diet of rice, bananas, and chicken makes me feel ill. I also have an occasional OAS reaction to bananas, strawberries, chocolate and almonds but IgE is negative on those foods. I can have a bit of lemon or lime but other citrus makes my face swell (paratoid glands) like crazy and my throat itches and is sore for days. I also tend to get raspy and lethargic. So I looked up histamine when I got home and found this information. So many of the foods high in histamine correspond with what's been bothering me. Foods high in histamine: 1. Champagne (76 mg/4 Oz.) 2. Sauerkraut (23 mg/3.5 Oz.) 3. Tofu (as high as 22 mg/3.5 Oz.) 4. Parmesan Cheese (15 mg/3.5 Oz.) 5. Beer (7 mg/pint) Beers vary in histamine content, with top fermented beers being higher in histamine. 6. Sausage (6 mg/3.5 Oz.) Fresh sausage is often lower in histamine than the cured/aged sausage. 7. Blue Cheese (5 mg/3.5 Oz.) 8. Red Wine (3.5 mg/4 Oz.) 9. Eggplant (3 mg/3.5 Oz.) 10. Tomato Ketchup (2 mg/3.5 Oz.) 11. Canned Fish (tuna, salmon, herring) (2 mg/3.5 Oz.) (I'm soy and lactose intolerant and beer always bothered me, but gluten free now anyways, wine gives me a raging headache if I have more than 1 glass) *Certain foods (even food that is low in histamine) can stimulate the release of histamine from mast cells (a type of immune cell). These foods include bananas, tomatoes, strawberries, pineapple, nuts, peanuts, shellfish, spinach, egg white and chocolate. (source: http://www.reverta.com/blog/histamine/top-10-histamine-containing-foods/) I bolded the foods that I seem to react to. I wonder if this is the missing link? edited to add: forgot to mention that doc put me on a med that inhibits histamine in the gut (histamine in gut causes D - who knew?) and suggested I also use an over the counter allergy med. I'm to do this for a month and see if it makes a difference.