First Menstrual Period gluten-free, Feeling Aweful! in Coping with Celiac Disease Posted July 29, 2011 · Report to Admin If it's any consolation my periods are way better since I went gluten free. They are less painful, shorter and best of all I have so much less PMS beforehand - it used to be awful and last up to two weeks before my period started. I used to feel like my hormones ruled my life - in a very negative way! They are not very regular now, but that could be because of the stress of imminent emigration... I agree with the idea that cycles have a run in time of a couple of months - it may take a while to see positive changes, but yes, absolutely gluten issues affect hormones in the body - how about the effect on thyroid levels for an example? Gluten/wheat derivatives turn up in the weirdest places. It really wouldn't surprise me if it was in sanitary products too.