Newly Diagnosed Osteopenia in Related Issues & Disorders Posted July 30, 2007 · Report to Admin Miacalcin is for women past menopause that have osteopenia or osteoporosis, not younger women still in menses. After questioning my doctor about it, she told me that this medication is not very effective and it's the delivery system that's the problem. Here's another view of Miacalcin. I'm a 62 yr old male dx'ed w/ osteoporosis when I was 55. For the first year my dr prescribed Miacalcin and I had outstanding results - 5% improvement in the spine in 12 months! (3% with Fosamax is considered good.) Then along came Fosamax and he was convinced by the Pharma salesman that Fosamax was a better deal, so I was switched. For the next 4 years I had hardly any improvement in bone density. Plus I subsequently learned that Fosamax is incorporated into your bones for life, so if any of the "rare" side effects such as jaw bone death (osteonecrosis) becomes a problem, you are stuck. There is no antidote. I stopped taking Fosamax 2 yrs ago partially because I was planning some dental work but mainly because I was not comfortable with the risk (Vioxx comes to mind). Recently I had my regular DEXA bone density scan and my results had declined. So I asked my (different)dr to prescribe Miacalcin again, and I got the same story about it not being very effective, etc. It sounded like a sales pitch for Fosamax; however, since I had a previous history of good results with Miacalcin I did some research on Pubmed and lo and behold there are lots of published papers on good results with calcitonin treatment(Miacalcin). I gave my dr a stack of these papers and I think have her convinced to rx Miacalcin. From one of her comments it sounds like she may be under significant constraint against rx'ing Miacalcin; my guess due to Pharma influence. I think the manufacturer of Miacalcin just doesn't have as good of marketing as the Fosamax folks. For the record, Miacalcin (calcitonin) is a natural hormone with no known major side effects (minor side effects include drippy nose [it's a nose spray] and has performed favorably in many studies, particularly on the spine. Fosamax has several significant side effects (gastro problems, jaw bone death) and is with you for life.