Celiac.com Sponsor (A1):

Celiac.com Sponsor (A1-m):


Advanced Members
  • Content Count

  • Joined

  • Last visited

  • Days Won


RMJ last won the day on December 25 2020

RMJ had the most liked content!

About RMJ

  • Rank
    Star Contributor

Profile Information

  • Gender

Recent Profile Visitors

11,951 profile views

  1. Celiac antibody tests are immunoassays.  They use antibodies to detect antibodies.  I am a scientist and used to develop this type of assay.  They are NOT perfect.  Even those approved by the FDA (or Canadian equivalent) can give false positives and false negatives.  However, MOST positives and negatives are real.  

    I looked up the FDA information on the Bioplex assay (type indicated in your lab results).  They occasionally got false positives from Crohns and rheumatoid arthritis, about one in 20 patients with those disorders came up positive. 

    One thing that might help you determine if your positives are real or not - after being carefully gluten free for at least six months, see if your antibody levels go down significantly.  This would not be meaningful if your diet is being contaminated with gluten (which perhaps it is if you're not feeling any better)?  So if levels don't go down it could be either that you had a false positive, or gluten contamination.

    I hope you find answers.


  2. I think you could taste the difference if you do it with foods.  Instead, you could get empty gelatin capsules, fill some with a gluten free flour, and fill the others with actual gluten.  They might look a bit different, but your partner could hand them to you each day when your eyes were closed.  With pure gluten you wouldn't have to take too many each day.

  3. How far do you go in avoiding processed foods that may have been contaminated before they get to you?  At first I just avoided anything with gluten-containing ingredients.  My antibodies went down but not to normal levels.  I had to use Fasano's gluten contamination elimination diet:


  4. Usually the ranges I've seen for positive are >3, or >19.  I think it is likely that you are high positive for the two celiac tests.  (The Immunoglobulin A test is not a test for celiac, it is to be sure your IgA is in the normal range because if not, the other tests aren't valid if they are negative).

    Keep eating gluten until you see the GI in case he wants to do a biopsy to confirm the diagnosis.

  5. On November 3, 2015 at 6:36:33 PM, Seeking said:

      I am okay with being gluten free but wonder if the blood test could be wrong. Should I get another blood test?

    You probably know this, but just in case - if you have another blood test after you've done a good job being gluten free, it will probably be negative.  But that does not mean the first one was wrong.  It means you have celiac and are keeping it under control with your diet.

  6. Have all of your tests been done by the same lab?  Unlike blood glucose and Vitamin D, different labs have different units and different ranges for celiac tests so they can't be compared.

    TTG and DGP are both celiac tests.  They are looking for different types of antibodies which may be involved.  They do NOT both have to be positive to indicate celiac.  One is enough.  Hopefully nvsmom will chime in with the explanation of the differences, or someone will quote her.

    If you don't eat gluten your numbers can get to the negative range, it may just take a while.  I'm almost there after 3 years.

    I hope you get some answers and feel better soon.