The Lyme Disease Thread in Food Intolerance & Leaky Gut Posted July 27, 2011 · Report to Admin Hi, I'm new to this board and I'm happy to see there so much support and information from it! I have a question, if anyone would happen to know it. My sister has had peripheral neuropathy (burning/tingling/vibration in hands/feet and other places) for ~2years, and recently, she did the Igenex test. Here were the results: IGM: 31 ++ 41 IND 83-93 IND Rest negative IGG: 30 + 39 IND 41 ++ Rest negative CD57 Count: 37 The above doesn't classify as a true positive, but I was wondering if people had some thoughts/insight into the above results? Thank-you. With symptoms I would bet a lyme doctor would give a diagnosis based on this test. It's a clinical diagnosis. Bands 30 and 31 can actually be retested to clarify whether it's positive from Lyme or from cross-reactivity. This is a very interesting thread. I've been gluten free for almost five years (self diagnosed) and staying off gluten seems to improve my immune system. Two years ago I was tested for lyme disease, and the test was negative, so I was happy (not knowing anything about how difficult it is to test for lyme disease). But my doctor did notice a very low IgM value, and several other tests later still showing IgM deficiency. As I understand it, an IgM deficiency can be an indication of an autoimmune disease, so I suggested to my doctor, that he did a celiac test. A couple of months ago I prepared for the test doing a four weeks gluten challenge. My ttg blood test was negative, but my symptoms suggested a non celiac gluten sensitivity. Good to know, and easy for me to return to my gluten free diet. But my symptoms would not go away again, and they got worse after a tick bite. I did not get the bullseye rash, but symptoms were felt while the tick was sucking blood from my leg. I have almost always lived in a high risk area, and have had hundreds of tick bites before this one. The ELISA test for lyme disease is now positive. The interesting thought is, did I get lyme disease because gluten had weakened my immune system, or am I gluten intolerant because I have lyme disease? I am currently doing a three weeks doxycycline treatment, and if it helps, I am willing to try to eat gluten again. I would bet gluten sentivity as a result of Lyme. Once I treated Lyme, my gluten sensitivity went away.