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  • JillianC
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  • Gluten-Free Sisters :)
  • Eab12's Celiac Blog
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  • Cheryl
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  • Celiac Teen
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  • Coeliac Disease or Coeliac Sprue or Non Tropical Sprue
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  • Madison Papers: Living Gluten-Free in a Gluten-Full World
  • babinsky's Blog
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  • Celiac Diagnosis at Age 24 months in 1939
  • Sandy R's Blog
  • mary m's Blog
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  • Guts & Brains
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  • Jersey Shore wheat no more's Blog
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  • glutenfreecosmeticcounter
  • Reasons Why Tummy tuck is considered best to remove unwanted belly fat?
  • alfgarrie's Blog
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  • lws' Blog
  • KMBC2014's Blog
  • Musings and Lessons Learned
  • txwildflower65's Blog
  • Uncertain
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  • jferguson
  • tiffjake's Blog
  • KCG91's Blog
  • Yolo's Herbs & Other Healing Strategies
  • scrockwell's Blog
  • Sandra45's Blog
  • Theresa Marie's Blog
  • Skylark's Blog
  • JessicaB's Blog
  • Anna'sMommy's Blog
  • Skylark's Oops
  • Jehovah witnesses
  • Celiac in Seattle's Blog
  • March On
  • honeybeez's Blog
  • The Liberated Kitchen, redux
  • onceandagain's Blog
  • JoyfulM's Blog
  • keepingmybabysafe's Blog
  • To beer, with love...
  • nana b's Blog
  • kookooto's Blog
  • SunnyJ's Blog
  • Mia'smommy's Blog
  • Amanda's Blog
  • jldurrani's Blog
  • Why choosing Medical bracelets for women online is the true possible?
  • Carriefaith's Blog
  • acook's Blog
  • REAGS' Blog
  • gfreegirl0125's Blog
  • Gluten Free Recipes - Blog
  • avlocken's Blog
  • Thiamine Thiamine Thiamine
  • wilbragirl's Blog
  • Gluten and Maize-Free (gluten-free-MF)
  • Elimination Diet Challenge
  • DJ 14150
  • mnsny's Blog
  • Linda03's Blog
  • GFinDC's Blog
  • Kim UPST NY's Blog
  • cmc's Blog
  • blog comppergastta1986
  • JesikaBeth's Blog
  • Melissa
  • G-Free's Blog
  • miloandotis' Blog
  • Confessions of a Celiac
  • Know the significance of clean engine oil
  • bobhayes1's Blog
  • Robinbird's Blog
  • skurtz's Blog
  • Olivia's Blog
  • Jazzdncr222's Blog
  • Lemonade's Blog
  • k8k's Blog
  • celiaccoach&triathlete's Blog
  • Gluten Free Goodies
  • cherbourgbakes.blogspot.com
  • snow dogs' Blog
  • Rikki Tikki's Blog
  • lthurman1979's Blog
  • Sprue that :)'s Blog
  • twinkletoes' Blog
  • Ranking the best gluten free pizzas
  • Gluten Free Product
  • Wildcat Golfer's Blog
  • Becci's Blog
  • sillyker0nian's Blog
  • txplowgirl's Blog
  • Gluten Free Bread Blog
  • babygoose78's Blog
  • G-freegal12's Blog
  • kelcat's Blog
  • Heavy duty 0verhead crane
  • beckyk's Blog
  • pchick's Blog
  • NOT-IN-2gluten's Blog
  • PeachPie's Blog
  • Johny
  • Breezy32600's Blog
  • Edgymama's Gluten Free Journey
  • Geoff
  • audra's Blog
  • mfrklr's Blog
  • 2 chicks
  • I Need Help With Bread
  • the strong one has returned!
  • sabrina_B_Celiac's Blog
  • Gluten Free Pioneer's Blog
  • Theanine.
  • The Search of Hay
  • Vanessa
  • racecar16's Blog
  • JCH13's Blog
  • b&kmom's Blog
  • Gluten Free Foodies
  • NanaRobin's Blog
  • mdrumr8030's Blog
  • Sharon LaCouture's Blog
  • Zinc, Magnesium, and Selenium
  • sao155's Blog
  • Tabasco's Blog
  • Amanda Smith
  • mmc's Blog
  • xphile1121's Blog
  • golden exch
  • kerrih's Blog
  • jleb's Blog
  • RUGR8FUL's Blog
  • Brynja's Grain Free Kitchen
  • schneides123's Blog
  • Greenville, SC Gluten-Free Blog
  • ramiaha's Blog
  • Kathy P's Blogs
  • rock on!'s Blog
  • Carri Ninja's Blog
  • jerseygirl221's Blog
  • Pkhaselton's Blog
  • Hyperceliac Blog
  • abbiekir's Blog
  • Lasister's Thoughts
  • bashalove's Blog
  • Steph1's Blog
  • Etboces
  • Rantings of Tiffany
  • GlutenWrangler's Blog
  • kalie's Blog
  • Mommy Of A Gluten Free Child
  • ready2go's Blog
  • Maureen
  • Floridian's Blog
  • Bobbie41972's Blog
  • Everyday Victories
  • Intolerance issue? Helpppp!
  • Feisty
  • In the Beginning...
  • Cheri46's Blog
  • Acne after going gluten free
  • sissSTL's Blog
  • Elizabeth19's Blog
  • LindseyR's Blog
  • sue wiesbrook's Blog
  • I'm Hungry's Blog
  • badcasper's Blog
  • M L Graham's Blog
  • Wolicki's Blog
  • katiesalmons' Blog
  • CBC and celiac
  • Kaycee's Blog
  • wheatisbad's Blog
  • beamishmom's Blog
  • Celiac Ninja's Blog
  • scarlett54's Blog
  • GloriaZ's Blog
  • Holly F's Blog
  • Jackie's Blog
  • lbradley's Blog
  • TheSandWitch's Blog
  • Ginger Sturm's Blog
  • The Struggle is Real
  • whataboutmary's Blog
  • JABBER's Blog
  • morningstar38's Blog
  • Musings of a Celiac
  • Celiacchef's Blog
  • healthygirl's Blog
  • allybaby's Blog
  • MGrinter's Blog
  • LookingforAnswers15's Blog
  • Lis
  • Alilbratty's Blog
  • 3sisters' Blog
  • MGrinter's Blog
  • Amanda
  • felise's Blog
  • rochesterlynn's Blog
  • mle_ii's Blog
  • GlamourGetaways' Blog
  • greendog's Blog
  • Tabz's Blog
  • Smiller's Blog
  • my vent
  • newby to celiac?'s Blog
  • siren's Blog
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  • Relieved and confused
  • carb bingeing
  • scottish's Blog
  • maggiemay832's Blog
  • Cristina Barbara
  • ~~~AnnaBelle~~~'s Blog
  • nikky's Blog
  • Suzy-Q's Blog
  • mfarrell's Blog
  • Kat-Kat's Blog
  • Kelcie's Blog
  • cyoshimit's Blog
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  • My girlfriend has celiacs and she refuses to see a doctor
  • Ki-Ki29's Blog
  • mailmanrol's Blog
  • Sal Gal
  • WildBillCODY's Blog
  • Ann Messenger
  • aprilz's Blog
  • the gluten-free guy
  • gluten-free-wifey's Blog
  • Lynda MEADOWS's Blog
  • mellajane's Blog
  • Jaded's Celiac adventures in a non-celiac world.
  • booboobelly18's Blog
  • Dope show
  • Classic Celiac Blog
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  • Bada
  • Sherry's blurbs
  • addict697's Blog
  • MIchael530btr's Blog
  • Shawn C
  • antono's Blog
  • Undiagnosed
  • little_d's Blog
  • Gluten, dairy, pineapple
  • The Fat (Celiac) Lady Sings
  • Periomike
  • Sue Mc's Blog
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  • It's just one cookie!
  • Kimmy
  • jacobsmom44's Blog
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  • You're Prescribing Me WHAT!?!
  • Kimmy
  • nybbles's Blog
  • Karla T.'s Blog
  • Young and dealing with celiacs
  • Celiac.com Podcast Edition
  • LCcrisp's Blog
  • ghfphd's allergy blog
  • https://www.bendglutenfree.com/
  • Costume's and GF Life
  • mjhere69's Blog
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  • CeliacChoplin
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  • William Parsons
  • Gluten Free Breeze (formerly Brendygirl) Blog
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  • Daily Life and Compromising
  • Vonnie Mostat
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  • Sandra Lee's Blog
  • Demertitis hepaformis no Celac
  • Vonnie Mostat, R.N.
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  • Kim
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  • Living in the Gluten Free World
  • lisajs38's Blog
  • Mary07's Blog
  • Treg immune celsl, short chain fatty acids, gut bacteria etc.
  • questions
  • A Blog by Yvonne (Vonnie) Mostat, RN
  • ROBIN
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  • Adventures of a Gluten Free Mom
  • Fiona S
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  • Carla
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  • SimplyGF Blog
  • Jim L Christie
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  • Alcohol, jaundice, and celiac
  • kmh6leh's Blog
  • Gluten Free Mastery
  • james
  • danandbetty1's Blog
  • Feline's Blog
  • Linda Atkinson
  • Auntie Lur: The Blog of a Young Girl
  • KathyNapoleone's Blog
  • Gluten Free and Specialty Diet Recipes
  • Why are people ignoring Celiac Disease, and not understanding how serious it actually is?
  • miasuziegirl's Blog
  • KikiUSA's Blog
  • Amyy's Blog
  • Pete Dixon
  • abigail's Blog
  • CHA's Blog
  • Eczema or Celiac Mom?'s Blog
  • Thoughts
  • International Conference on Gastroenterology
  • Deedle's Blog
  • krackers' Blog
  • cliniclfortin's Blog
  • Mike Menkes' Blog
  • Juanita's Blog
  • BARB OTTUM
  • holman's Blog
  • It's EVERYWHERE!
  • life's Blog
  • writer ann's Blog
  • Ally7's Blog
  • Gluten Busters: Gluten-Free Product Alerts by Celiac.com
  • K Espinoza
  • klc's Blog
  • Pizza&beer's Blog
  • CDiseaseMom's Blog
  • sidinator's Blog
  • Dr Rodney Ford's Blog
  • How and where is it safe to buy cryptocurrency?
  • lucedith's Blog
  • Random Thoughts
  • Kate
  • twin#1's Blog
  • myadrienne's Blog
  • Nampa-Boise Idaho
  • Ursa Major's Blog
  • bakingbarb's Blog
  • Does Celiac Cause Sensitivites To Rx's?
  • delana6303's Blog
  • psychologygrl25's Blog
  • Alcohol and Celiac Disease
  • How do we get it???
  • cooliactic_BOOM's Blog
  • GREAT GF eating in Toronto
  • Gluten-free Food Recommendations!
  • YAY! READ THIS!!
  • BROW-FREE DIET BLOG
  • carib168's Blog
  • A Healing Kitchen
  • Shawn s
  • AZ Gal's Blog
  • mom1's Blog
  • The Beginning - The Diagnosis
  • PeweeValleyKY's Blog
  • solange's Blog
  • Cate K's Blog
  • Layered Vegetable Baked Pasta (gluten-free Vegetarian Lasagna)
  • Gluten Free Teen by Ava
  • mtdawber's Blog
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  • DCE's Blog
  • Infertility and Celiac Disease
  • What to do in the Mekong Delta in 1 Day?
  • glutenfreenew's Blog
  • Living in the Garden of Eden
  • toddzgrrl02's Blog
  • redface's Blog
  • Gluten Free High Protein
  • Ari
  • Great Harvest Chattanooga's Blog
  • CeliBelli's Blog
  • Aboluk's Blog
  • redface's Blog
  • Being in Control of Your Gluten-Free Diet on a Cruise Ship
  • jayshunee's Blog
  • lilactorgirl's Blog
  • Yummy or Yucky Gluten-Free Foods
  • Electra's Blog
  • Cocerned husband's Blog
  • lilactorgirl's Blog
  • A Little History - My Celiac Disease Diagnosis
  • How to line my stomach
  • sewfunky's Blog
  • Oscar's Blog
  • Chey's Blog
  • The Fun of Gluten-free Breastfeeding
  • Dawnie's Blog
  • Sneaky gluten free goodness!
  • Chicago cubs shirts- A perfect way of showing love towards the baseball team!
  • Granny Garbonzo's Blog
  • GFzinks09's Blog
  • How do I get the Celiac.com podcast on my mp3 player?
  • quantumsugar's Blog
  • Littlebit's Blog
  • Kimberly's Blog
  • Dayz's Blog
  • Swimming Breadcrumbs and Other Issues
  • Helen Burdass
  • celiacsupportnancy's Blog
  • Life of an Aggie Celiac
  • kyleandjra.jacobson's Blog
  • Hey! I'm Not "Allergic" to Wheat!
  • FoOdFaNaTic's Blog
  • Wendy Cohan, RN's Gluten-Free and Dairy-Free Cooking Classes
  • Lora Derry
  • Dr. Joel Goldman's Blog
  • The Ultimate Irony
  • Lora Derry
  • ACK514's Blog
  • katinagj's Blog
  • What Goes On, Goes In (Gluten in Skin Care Products)
  • What’s new in hydraulic fittings?
  • cannona3's Blog
  • citykatmm's Blog
  • Adventures in Gluten-Free Toddling
  • tahenderson67's Blog
  • The Dinner Party Drama—Two Guidelines to Assure a Pleasant Gluten-Free Experience
  • What’s new in hydraulic fittings?
  • sparkybear's Blog
  • justbikeit77's Blog
  • To "App" or Not to "App": The Use of Gluten Free Product List Computer Applications
  • Onangwatgo
  • Raine's Blog
  • lalla's Blog
  • To die for Cookie Crumb Gluten-Free Pie Crust
  • DeeTee33's Blog
  • http://glutenfreegroove.com/blog/
  • David2055's Blog
  • Gluten-Free at the Fancy Food Show in San Francisco
  • Kup wysokiej jakości paszporty, prawa jazdy, dowody osobiste
  • Janie's Blog
  • Managing Hives & Gluten Allergies
  • Bogaert's Blog
  • Janie's Blog
  • RaeD's Blog
  • Dizzying Disclaimers!
  • Dream Catcher's Blog
  • PinkZebra's Blog
  • Hibachi Food and Hidden Gluten Hazards (How to Celebrate Gluten-Free)
  • jktenner's Blog
  • OhSoTired's Blog
  • PinkZebra's Blog
  • gluten-free Lover's Blog
  • Gluen Free Health Australia
  • Melissamb21's Blog
  • Andy C's Blog
  • halabackgirl9129's Blog
  • Liam Edwards' Blog
  • Celiac Disease in Africa?
  • Suz's Blog
  • Gluten-Free Fast Food
  • Eldene Goosen
  • mis_chiff's Blog
  • gatakat's Blog
  • macocha's Blog
  • Newly Diagnosed Celiacs Needed for Study in Chicago
  • Elaine Anne
  • Poor Baby's Blog
  • the loonie celiac's Blog
  • jenlex's Blog
  • Sex Drive/Testosterone can be Depleted by Certain Foods
  • Sharon
  • samantha79's Blog
  • 21 Months into the Gluten-free Diet
  • WashingtonLady's Blog-a-log
  • James S. Reid's Blog
  • Living with a Gluten-Free Husband
  • Diane King
  • runner girl's Blog
  • kp3972's Blog
  • ellie_lynn's Blog
  • trayne91's Blog
  • Gluten-free Lipstick!
  • Nonna2's Blog
  • Schar Chocolate Hazelnut Bar (Gluten-Free)
  • pnltbox27's Blog
  • Live2BWell's Blog
  • melissajohnson's Blog
  • nvsmom's Blog
  • Diagnosed with Celiac Disease and Still Sick
  • snowcoveredheart's Blog
  • Gluten Free Nurse
  • Gluten-Free Frustration!
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  1. Hello! I would like to preface this by saying I’m experiencing a lot of brain fog and gluten ataxia while writing this so I really apologize if this post seems disorganized. Also I’m a 24 year old woman to give this post some context. For a very long time now I’ve always had very very bad digestive issues that have only gotten worse over time. I was diagnosed with POTS when I was 14 and my doctor always told me my gut problems are from my pots. I also was diagnosed with Ankylosing Spondylitis at age 22. But I looked into celiac and have read so many articles and a few books about it and I realized I had so many symptoms in common with celiac. So I decided to cut gluten out of my diet and a week later my entire life changed. I didn’t have any digestive problems at all, my brain fog was cleared, I no longer felt uncoordinated, my arthritis was so much better, and all my pots symptoms vanished. It was incredible. But about a month and a half later I started feeling symptoms I’ve never felt before. I constantly felt nauseous and hungry at the same time, my head is constantly hurting, my digestive issues are worse than they’ve ever been, I’m constantly fatigued, my arthritis is so bad and crippling, my anxiety and depression are back and I have panic attacks every night and really struggle falling asleep. It’s complete and utter hell. I share a kitchen with my family and I do everything in my capacity to make sure my food doesn’t get cross contaminated. I’ve completely cut out dairy recently but it doesn’t seem to make a big difference. I can no longer function especially with my gluten ataxia and brain fog. Is this normal for symptoms to reappear in the healing process? I do everything in my power to make sure I don’t get anything cross contaminated and double triple check ingredients lists to make sure it doesn’t contain gluten or is processed in any facility with gluten. I don’t even eat at restaurants and cook everything at home. I’ve also checked medications, skincare products, and vitamins and supplements to make sure I’m not getting gluten from that.
  2. Celiac.com 06/06/2020 - Patients with depression are told they have a chemical imbalance. If someone else in their family is also depressed, the “gene card” is played. “Your depression is genetic”, they are told. I have been in practice for over 20 years and I find the above data to be false. Consistently we find patients who are suffering from depression and anxiety to be gluten sensitive. How could a food cause depression? Let’s take a look: After the digestive tract, the system most commonly affected by gluten is the nervous system. It is thought that depression can be caused by gluten in one of two ways, inflammation and protein absorption. The first is through the inflammatory changes caused by gluten. A gluten sensitive individual’s immune system responds to the protein gliadin. Unfortunately, that protein is structurally similar to body proteins, including those of the brain and nerve cells. A cross reaction can occur when the immune system “confuses” body proteins with gliadin proteins. This is called cellular mimicry and the result is inflammation where the body is attacking its own tissues. When inflammation happens in the brain and nervous system, a variety of symptoms can occur, including depression. Research shows that patients with symptoms involving the nervous system suffer from digestive problems only 13% of the time. This is significant because mainstream medicine equates gluten sensitivity almost exclusively with digestive complaints. In a study examining blood flow in the brain, 15 patients with untreated celiac disease were compared to 15 patients treated with a gluten-free diet for one year. The findings were amazing. In the untreated group, 73% had abnormalities in brain circulation by testing while only 7% in the treated group showed any abnormalities. The patients with the brain circulation problems were frequently suffering from anxiety and depression as well. In addition to circulation problems, other research looks at the association between gluten sensitivity and its interference with protein absorption. Specifically the amino acid tryptophan can be deficient. Tryptophan is a protein in the brain responsible for a feeling of well-being and relaxation. A deficiency can be correlated to feelings of depression and anxiety. Our society is too willing to accept “chemical imbalance” as an explanation for their symptoms. Instead of getting to the root cause of the condition, we simply swallow a pill—a pill that in the case of anti-depressants has very dangerous and sometimes lethal side effects. The frequency with which we are able to successfully taper patients off their anti-depressants is considered “unbelievable” by many mainstream doctors, yet we do it regularly. How is that possible? We actually diagnose the root cause of the depression. Frequently the culprit is gluten.

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  4. Traveling with celiac is really draining. Trying to find food you can eat, feeling like a burden to the people you're traveling with, and worrying about having a reaction that spoils the trip.
  5. Celiac.com 09/01/2023 - Celiac disease, a chronic autoimmune disorder triggered by the consumption of gluten, has long been associated with gastrointestinal symptoms and malabsorption issues. However, a growing body of research has shed light on an often-overlooked aspect of celiac disease: its potential impact on mental health. The intricate relationship between the gut and the brain, known as the gut-brain axis, is garnering attention for its role in influencing both physical and mental well-being. As scientists delve deeper into the complexities of this connection, a compelling picture emerges—one that suggests that the health of the gut could play a pivotal role in shaping our mental state. In this article, we embark on a journey through the fascinating landscape of celiac disease and its intricate relationship with mental health. We'll explore the mechanisms that underlie the gut-brain axis and how they contribute to various mental health conditions. We'll delve into the scientific evidence that links celiac disease to conditions such as anxiety, depression, ADHD, autism spectrum disorders, schizophrenia, and bipolar disorder. Additionally, we'll examine how nutritional deficiencies stemming from untreated celiac disease may exacerbate these mental health issues. As we navigate this intricate web of connections, we'll address the question of whether a gluten-free diet—one that is central to managing celiac disease—could also hold the key to alleviating mental health symptoms in gluten sensitive individuals. The Gut-Brain Axis: Exploring the Connection The intricate interplay between the gut and the brain is a captivating area of scientific inquiry that has been gaining momentum in recent years. This communication network, known as the gut-brain axis, serves as a two-way highway along which information travels between these seemingly distant organs. The gut, often referred to as the "second brain," is home to a complex ecosystem of trillions of microorganisms, collectively known as the gut microbiota. These microorganisms play a pivotal role in maintaining the gut's health and influencing various bodily processes, including those related to mental well-being. The gut-brain axis operates through intricate signaling pathways that involve both direct and indirect communication. The vagus nerve, a long cranial nerve that connects the brain to the abdomen, acts as a vital conduit for this communication. In addition, a dynamic network of biochemical messengers, including neurotransmitters, hormones, and immune molecules, enables the gut and brain to send and receive messages. The gut microbiota, which includes a diverse range of bacteria, viruses, fungi, and other microorganisms, has emerged as a key player in shaping this communication. These microbes contribute to the production of neurotransmitters such as serotonin, dopamine, and gamma-aminobutyric acid (GABA), which are not only crucial for brain function but also have a profound impact on mood regulation. A growing body of research suggests that imbalances in the gut microbiota, often referred to as dysbiosis, may contribute to mental health disorders. Understanding the gut-brain axis offers a fresh perspective on the way physical and emotional health intersect. Factors that disrupt the balance of this delicate axis, such as chronic inflammation, stress, and dietary choices, can have far-reaching consequences for mental health. As researchers unravel the intricate threads of this connection, they are uncovering insights that may pave the way for innovative therapeutic approaches to address mental health conditions, particularly in individuals with underlying conditions such as celiac disease. Celiac Disease and Mental Health: A Complex Link As we journey deeper into the realm of celiac disease and its implications for mental health, we encounter a multifaceted connection that underscores the complexity of human physiology. Celiac disease, an autoimmune disorder triggered by the ingestion of gluten—a protein found in wheat, barley, and rye—has long been recognized for its impact on the gastrointestinal system. However, the story does not end there. A growing body of research suggests that the effects of celiac disease extend beyond the gut, reaching into the realm of mental health. While the exact mechanisms that link celiac disease to mental health conditions are still being unraveled, several factors contribute to this intricate relationship. One of the key elements is inflammation. Untreated celiac disease triggers an immune response that leads to chronic inflammation within the small intestine. This inflammation has the potential to extend beyond the gut, affecting other systems within the body—including the brain. This raises the intriguing possibility that the inflammation associated with celiac disease could play a role in the development or exacerbation of mental health issues. Moreover, the gut-brain axis comes into play once again. The gut microbiota, a collection of microorganisms residing in the gastrointestinal tract, plays a significant role in influencing both physical and mental health. Emerging research suggests that the gut microbiota of individuals with celiac disease may differ from those without the condition. This dysbiosis could potentially impact the production of neurotransmitters, such as serotonin, that are crucial for mood regulation. The prevalence of mental health issues among individuals with celiac disease adds another layer of complexity to the equation. Studies have shown that individuals with celiac disease are at an increased risk of conditions such as anxiety, depression, and attention disorders. While the exact causal relationship between celiac disease and these conditions remains under investigation, the implications are undeniable. Understanding the connections between celiac disease and mental health not only sheds light on the broader impact of the disorder but also offers new avenues for therapeutic interventions. Anxiety and Celiac Disease: Breaking Down the Ties Research has revealed a compelling link between celiac disease and anxiety disorders. While the exact mechanisms remain a subject of ongoing investigation, several factors contribute to this connection. One notable element is the role of inflammation. Untreated celiac disease triggers an immune response that leads to chronic inflammation in the small intestine. This inflammation may extend beyond the gut, affecting other areas of the body, including the brain. Inflammation is increasingly recognized as a potential contributor to anxiety, as it can disrupt neurotransmitter balance and neural pathways. In addition to inflammation, nutritional deficiencies resulting from malabsorption in celiac disease could exacerbate anxiety symptoms. Nutrients like B vitamins, particularly B12 and folate, are essential for maintaining optimal neurological function. Deficiencies in these vitamins have been linked to mood disorders, including anxiety. The gut's compromised ability to absorb these nutrients can hinder their availability to the brain, potentially amplifying feelings of anxiety. As for the impact of a gluten-free diet on anxiety, findings are promising but complex. Some individuals with celiac disease report a reduction in anxiety symptoms after adopting a gluten-free diet. However, the relationship is not one-size-fits-all. It's important to note that anxiety can stem from various factors, and while dietary changes might alleviate symptoms in some cases, they may not be a standalone solution for everyone. Seeking professional guidance from both medical and mental health experts is crucial for individuals with celiac disease experiencing anxiety. Depression and Celiac Disease: Searching for Clues Among the spectrum of mental health conditions, depression stands as a particularly intricate puzzle. Its origins are multifaceted, influenced by a combination of genetic, environmental, and physiological factors. As researchers delve into the complexities of depression, a new avenue of exploration emerges—one that involves the interplay between celiac disease and this mood disorder. Depression, characterized by persistent feelings of sadness, hopelessness, and a lack of interest in activities, affects millions of individuals worldwide. Interestingly, studies have shown a higher prevalence of depression among individuals with celiac disease compared to the general population. The question that naturally arises is whether there is a genuine connection between these two seemingly unrelated conditions. One avenue of investigation lies in the realm of serotonin, a neurotransmitter known for its role in regulating mood and emotions. An estimated 90% of serotonin is produced in the gastrointestinal tract, where the gut microbiota plays a significant role in its synthesis. Here, the gut-brain axis comes into play once again. Untreated celiac disease, with its potential to disrupt the balance of the gut microbiota, could potentially impact serotonin production and utilization. This disruption may contribute to the development or exacerbation of depressive symptoms. Moreover, nutritional deficiencies associated with celiac disease could play a role in the development of depression. Nutrients such as B vitamins, folate, and iron are essential for optimal neurological function. Malabsorption in celiac disease could lead to deficiencies in these nutrients, potentially affecting mood regulation. For instance, vitamin B12 deficiency has been linked to symptoms of depression, fatigue, and cognitive impairment—symptoms that often overlap with those of celiac disease. Could a gluten-free diet offer a ray of hope for individuals with celiac disease who also grapple with depression? While the research is ongoing and the results are variable, some individuals report improvements in their mood after adopting a gluten-free diet. This phenomenon raises intriguing possibilities regarding the connection between dietary choices and mental well-being. However, it's important to note that depression is a complex condition with diverse causes, and a gluten-free diet may not be a standalone solution for everyone. Consultation with medical and mental health professionals is essential for those considering dietary changes to manage their depression. Celiac Disease, ADHD, and Cognitive Function: Insights and Considerations Attention Deficit Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder that affects both children and adults, characterized by symptoms of inattention, hyperactivity, and impulsivity. While traditionally associated with behavioral and cognitive challenges, emerging research suggests a potential link between celiac disease and ADHD. The relationship between celiac disease and ADHD is complex and multifaceted. While definitive causality has not been established, studies have highlighted intriguing associations between the two conditions. Individuals with celiac disease seem to be at a higher risk of developing ADHD-like symptoms compared to the general population. Additionally, some research suggests that individuals with ADHD might have an increased prevalence of celiac disease. One plausible connection lies in the potential impact of untreated celiac disease on cognitive function. Nutritional deficiencies, often a consequence of malabsorption in celiac disease, can affect various aspects of cognitive performance. Nutrients like iron, zinc, and certain B vitamins are essential for optimal brain function. Deficiencies in these nutrients might contribute to attention difficulties and cognitive impairments often observed in individuals with ADHD. Furthermore, the gut-brain axis plays a role in shaping cognitive function and behavior. The gut microbiota, with its influence on neurotransmitter production and immune responses, could potentially impact the neural pathways associated with ADHD. Dysbiosis or imbalances in the gut microbiota might disrupt these pathways, contributing to the development or exacerbation of ADHD symptoms. Could adopting a gluten-free diet offer potential benefits for individuals with celiac disease who also experience ADHD-like symptoms? While the research is still unfolding, anecdotal evidence and some studies suggest that dietary changes might have positive effects on cognitive function and attention in individuals with celiac disease and ADHD. However, the outcomes vary, and the efficacy of a gluten-free diet for managing ADHD requires further investigation. It's essential for individuals to work closely with healthcare professionals when considering dietary interventions for managing ADHD symptoms. Autism Spectrum Disorders and Celiac Disease: An Evolving Understanding Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition characterized by a range of challenges in social interaction, communication, and behavior. While the exact causes of ASD remain elusive, researchers have been exploring potential links between celiac disease and autism, shedding light on intriguing intersections between the two. The relationship between celiac disease and ASD is a topic that continues to evolve. Studies investigating this connection have yielded mixed findings, with some suggesting a potential association and others failing to establish a clear link. Despite the ambiguity, there are notable overlaps in genetic and immunological factors between the two conditions, prompting researchers to delve deeper into the shared mechanisms. One avenue of exploration lies in the immune system's role in both celiac disease and ASD. Both conditions involve immune dysregulation and inflammation, suggesting that disruptions in the immune response could contribute to the development of both disorders. Shared genetic markers and pathways further underscore the potential connections between celiac disease and ASD. Additionally, nutritional deficiencies resulting from untreated celiac disease may play a role in the development of ASD symptoms. Nutrients like zinc, iron, and certain B vitamins are crucial for optimal neurological development. Deficiencies in these nutrients, which are common in individuals with celiac disease, could potentially impact brain development and function, potentially contributing to ASD symptoms. The question of whether a gluten-free diet could positively impact individuals with celiac disease and ASD remains a topic of interest. Some parents and caregivers have reported improvements in certain behaviors and symptoms in individuals with ASD after adopting a gluten-free diet. However, the results are variable, and the research landscape is complex. Rigorous scientific studies are needed to establish the potential benefits of dietary interventions for individuals with both celiac disease and ASD. Navigating the relationship between celiac disease and ASD requires a comprehensive approach that takes into account genetic, immunological, and nutritional factors. As researchers continue to explore this connection, individuals with celiac disease and caregivers of those with ASD are encouraged to collaborate with healthcare professionals to make informed decisions that consider the individual's unique needs and circumstances. Schizophrenia and Celiac Disease: Investigating the Intersection Schizophrenia, a complex and often debilitating mental health disorder, challenges our understanding of the intricate workings of the brain. Characterized by symptoms such as hallucinations, delusions, disorganized thinking, and impaired cognitive function, schizophrenia remains an enigma in the field of psychiatry. Recent research has sparked interest in the potential connections between celiac disease and schizophrenia, shedding light on an intersection that warrants further exploration. The relationship between celiac disease and schizophrenia is a topic of ongoing investigation, and while the evidence is limited, it presents intriguing insights into the possible links between immune dysregulation, inflammation, and brain function. Some studies suggest that individuals with celiac disease may be at a higher risk of developing schizophrenia-like symptoms compared to the general population. Furthermore, a shared genetic susceptibility between the two conditions raises the possibility of overlapping mechanisms. One avenue of inquiry involves the potential role of inflammation in both celiac disease and schizophrenia. Chronic inflammation, a hallmark of untreated celiac disease, has been proposed as a contributor to the development of schizophrenia symptoms. Immune molecules released during inflammation could impact neural circuits and neurotransmitter balance, potentially leading to the characteristic symptoms of schizophrenia. Moreover, the gut-brain axis comes into focus once again. The gut microbiota, with its influence on immune responses and neurotransmitter production, could play a role in shaping brain function and behavior. Alterations in the gut microbiota composition, often observed in individuals with celiac disease, may influence immune responses and inflammation, potentially contributing to the development or exacerbation of schizophrenia symptoms. As for the potential impact of a gluten-free diet on schizophrenia symptoms, the landscape is complex and the research is limited. Some case studies and anecdotal reports suggest that individuals with schizophrenia and celiac disease experienced improvements in their mental health after adopting a gluten-free diet. However, these outcomes are far from uniform, and more rigorous research is needed to establish the potential benefits of dietary interventions for managing schizophrenia. Understanding the potential connections between celiac disease and schizophrenia offers a fresh perspective on the intricate interplay between the immune system, inflammation, and brain function. As the scientific community continues to delve into this complex relationship, individuals with celiac disease and those with schizophrenia are encouraged to engage in open dialogues with healthcare professionals to make informed decisions that consider their unique circumstances. Bipolar Disorder and Celiac Disease: A Complex Interaction Bipolar Disorder, characterized by extreme shifts in mood, energy, and activity levels, presents a unique challenge in the realm of mental health. Individuals with bipolar disorder experience periods of elevated mood (mania) and periods of depression, often accompanied by changes in behavior and cognition. While the origins of bipolar disorder are multifaceted, researchers are uncovering potential connections between celiac disease and bipolar symptoms, shedding light on an intricate interplay that warrants exploration. The relationship between celiac disease and bipolar disorder is multifaceted and not fully understood. Studies exploring this connection have yielded mixed results, making it difficult to establish definitive causality. However, shared genetic factors and the potential impact of inflammation on brain function suggest potential links between the two conditions. One avenue of investigation involves the role of omega-3 fatty acids, essential nutrients with anti-inflammatory properties. Individuals with celiac disease are at risk of nutritional deficiencies, including deficiencies in omega-3 fatty acids. These deficiencies could potentially contribute to neuroinflammation and impact brain function, potentially exacerbating bipolar symptoms. Furthermore, the gut-brain axis enters the spotlight once again. The gut microbiota's influence on inflammation, neurotransmitter production, and immune responses makes it a key player in the relationship between celiac disease and bipolar disorder. Imbalances in the gut microbiota, often associated with celiac disease, could potentially contribute to immune dysregulation and impact mood regulation. The potential impact of a gluten-free diet on bipolar disorder symptoms remains a topic of interest. Some individuals with bipolar disorder and celiac disease have reported improvements in mood stability and overall well-being after adopting a gluten-free diet. However, the results are variable, and the research landscape is complex. Rigorous scientific studies are needed to establish the potential benefits of dietary interventions for individuals with both conditions. As researchers continue to explore the complex connections between celiac disease and bipolar disorder, individuals with celiac disease and those managing bipolar disorder are encouraged to engage in conversations with healthcare professionals. Understanding the potential impact of dietary choices and addressing nutritional deficiencies could hold promise in the realm of mental health, offering a comprehensive approach to managing bipolar disorder symptoms. The Impact of a Gluten-Free Diet on Mental Health As the intricate relationship between celiac disease and mental health unfolds, the question that looms large is whether a gluten-free diet—an essential component of managing celiac disease—could potentially have a positive impact on mental well-being. While the research is complex and the outcomes are variable, investigating the potential effects of a gluten-free diet on mental health conditions sheds light on a promising avenue of exploration. Anxiety and Depression: A Glimmer of Hope? For individuals with celiac disease who also experience anxiety and depression, the prospect of a gluten-free diet alleviating their symptoms is an intriguing one. While studies investigating the direct impact of a gluten-free diet on anxiety and depression are limited, some individuals report improvements in their mood and overall emotional well-being after adopting such a diet. The reasons behind these improvements are not fully understood, but they could stem from a combination of factors, including reduced inflammation and improvements in nutrient absorption. Attention and Cognitive Function: Enhancing Clarity? In the realm of attention disorders and cognitive function, the potential benefits of a gluten-free diet for individuals with celiac disease and ADHD remain under exploration. Anecdotal evidence suggests that some individuals experience improvements in attention and focus after adopting a gluten-free diet. However, rigorous scientific studies are needed to establish the efficacy of dietary interventions on cognitive function in individuals with ADHD. Autism Spectrum Disorders: Navigating Complexity For individuals with celiac disease and autism spectrum disorders, the potential impact of a gluten-free diet on symptoms remains a topic of debate. Some parents and caregivers report observed improvements in behavior and communication after removing gluten from the diet. However, the results are highly variable, and research findings have been mixed. It's crucial for individuals considering dietary changes to collaborate closely with healthcare professionals to make informed decisions that consider the individual's unique needs. Schizophrenia and Bipolar Disorder: A Bridge to Explore In the realm of severe mental health conditions like schizophrenia and bipolar disorder, the evidence regarding the impact of a gluten-free diet on symptoms is limited. While some case studies and anecdotal reports suggest potential benefits, the landscape is complex and the outcomes are far from uniform. The relationship between celiac disease, inflammation, and these conditions raises intriguing possibilities, but further research is needed to establish the potential role of dietary interventions. In the pursuit of understanding the impact of a gluten-free diet on mental health conditions, it's essential to approach dietary changes with caution. While the potential benefits are promising, it's important to recognize that dietary interventions are not a substitute for professional medical and mental health care. Consulting with healthcare providers who specialize in both celiac disease and mental health is crucial before making any significant changes to one's diet. Conclusion The intricate relationship between celiac disease and mental health unveils a captivating narrative that underscores the interconnectedness of the body and mind. As we navigate the complex landscape of the gut-brain axis, immune responses, and nutritional influences, a mosaic of connections emerges—highlighting the potential impact of celiac disease on a spectrum of mental health conditions. The gut-brain axis, a bidirectional communication network, serves as a bridge between the physical and emotional realms. The gut microbiota, immune responses, and inflammation play pivotal roles in shaping mental well-being. While the mechanisms are complex and multifaceted, the emerging research paints a compelling picture—one that invites us to consider new perspectives on mental health. From anxiety and depression to ADHD, autism spectrum disorders, schizophrenia, and bipolar disorder, each mental health condition weaves a unique thread in the tapestry of celiac disease's influence. Shared genetic factors, immune dysregulation, and nutritional deficiencies intermingle to create a symphony of interactions that challenge our understanding of the mind's intricate workings. As individuals with celiac disease and mental health conditions seek answers, it's essential to approach the journey with patience, curiosity, and a commitment to holistic well-being. While a gluten-free diet holds promise for some, it's not a panacea. Collaborating closely with healthcare professionals—those who specialize in both celiac disease and mental health—offers a comprehensive approach to addressing the nuanced connections between these realms. The exploration doesn't end here. As science continues to advance, our understanding of the gut-brain connection will deepen, unveiling new insights and potential interventions. The complexities of celiac disease's impact on mental health remind us of the intricate tapestry that makes us human—a tapestry woven with the threads of genetics, environment, biology, and experience. In the journey toward unraveling the gut-brain connection, we bridge the gap between the physical and emotional, gaining a deeper appreciation for the profound interplay that shapes our lives. As we move forward, let us continue to foster open dialogue, advance scientific inquiry, and empower individuals to make informed choices that honor both their physical health and mental well-being.
  6. Celiac.com 07/17/2023 - Celiac disease has been associated with higher levels of anxiety, but study evidence is scant. A team of researchers recently set out to measure the frequency of anxiety and depressive symptoms in Jordanian patients with celiac disease. The Research Team The research team included Sara Haj Ali, Rahaf Alqurneh, Awni Abu Sneineh, Bandar Ghazal, Lana Agraib, Layali Abbasi, Sufian Rifaei, and Tarek Mazzawi. They are variously affiliated with the department of Medicine, Al-Balqa Applied University, Al-Salt, JOR; the department Gastroenterology and Hepatology, University of Jordan, Amman, JOR; and the department of Food Science and Nutrition, Jerash University, Jerash, JOR. Celiac disease is a condition where the immune system reacts to gluten, causing intestinal problems and other symptoms. Researchers conducted a study to understand the frequency of anxiety and depressive symptoms in Jordanian patients with celiac disease. Anxiety and Depressive Symptom Questionnaire The study involved sending a questionnaire electronically to celiac disease patients through WhatsApp. The questionnaire asked about demographics, disease-related information, and assessed anxiety and depressive symptoms using validated scales. A total of 133 patients participated in the study, mostly females with an average age of 33.9 years. About one-third of the patients were not following a gluten-free diet, and more than half were experiencing symptoms at the time of the study. 83% Report Depressive Symptoms The prevalence of anxiety and depressive symptoms among the participants was found to be high, with 85% reporting anxiety symptoms and nearly 83% reporting depressive symptoms. There were no significant correlations found between the variables and the presence of anxiety or depressive symptoms. These findings highlight the significant proportion of Jordanian celiac disease patients who experience anxiety and depressive symptoms. Considering the potential impact on their quality of life, it is important for healthcare providers to screen celiac disease patients for psychiatric comorbidities and refer them for further evaluation if needed. This can help improve their overall well-being and provide appropriate support. Read more at Cureus. 2023 Jun; 15(6): e39842
  7. Hello All, I was recently diagnosed with Celiac a little over a month ago after losing 25 pounds, excruciating abdominal pains & extreme anxiety. In my blood work they also found a pretty bad Vitamin D deficiency (17, when the lowest normal level is 30). I am currently on a 50,000 IU/week pill for this. After about 3 weeks of a gluten free diet, the abdominal pains have pretty much subsided. However, it seems I have developed pain on the right side of my body only as well as other sensations such as pins & needles/numbness. I was recently in the ER after I felt numbness down the whole right side of my body, but my brain CT & MRI came back normal. I am now scheduled to go the neurologist for a possible lumbar puncture & spinal MRI to try and rule out MS all together. I have been told that Celiac & Anxiety can cause weird pains and different for everyone. I was just wondering if anyone else has experienced a one sided pain or sensations previously mentioned as I feel like I am going crazy. Is there any other supplements people have taken to help as well. Any input will greatly be appreciated. Thanks

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  9. Celiac.com 03/27/2023 - Celiac disease, a chronic inflammatory disorder of the intestines, affects about 1% of the world's population. Celiac disease causes diarrhea, abdominal discomfort, bloating, flatulence, and, in rare cases, constipation in the digestive tract. Since the identification of gluten as the disease-causing antigen, celiac patients have been treated with a gluten-free diet, which usually eliminates symptoms and restores gut health, but which also has limitations for some patients. Celiac disease is also associated with numerous neurological and psychological manifestations. A recent article details findings from the most recent study, but here we try to provide more comprehensive information. Neurological Manifestations of Celiac Disease The neurological manifestations of celiac disease are varied and can include psychiatric and neurological symptoms such as ataxia, peripheral neuropathy, seizures, headaches, cognitive impairment, and myoclonus. The specific mechanisms of celiac disease's neurological effects are still being researched, but they may involve gluten-mediated pathogenesis that can lead to antibody cross-reactions, immune-complex deposition, direct neurotoxicity, or extreme vitamin or food deficiencies. A gluten-free diet can alleviate most celiac disease symptoms, except for cortical myoclonus and dementia, which may require immunosuppressive therapy. However, there is currently no consensus on whether serological or neurophysiological data can accurately predict or monitor celiac disease-related neurological involvement. Treatment for gluten-related neurological symptoms typically involves embarking on a strict gluten-free diet as soon as possible, which can have a positive therapeutic effect for most cases. Symptomatic management may also be required. Immunosuppression is only used in cases where a gluten-free diet alone has not been beneficial or for patients with refractory celiac disease. Peripheral Neuropathy and Gluten Ataxia Peripheral neuropathy and gluten ataxia are common in celiac patients, with up to 39% of patients experiencing gluten neuropathy. Gluten-free diets have been shown to improve neuropathy and ataxia. Gluten ataxia is an uncommon immune-mediated neurological disease that can be difficult to identify. The early signs of ataxia may be subtle, but worsen if left untreated. Patients with gluten ataxia may experience structural alterations in different parts of the brain, including the cerebellum and thalamus, and have larger lateral ventricles. Higher Epilepsy Risk Celiac disease increases the risk of epilepsy, especially in children and adolescents. The presence of villus atrophy on follow-up biopsies may reduce the risk of epilepsy but does not affect hospitalizations for epilepsy emergencies. Unexplained epilepsy should prompt celiac disease screening since early identification and therapy may increase the effectiveness of anti-epileptic drugs. Celiac patients also have a higher prevalence of migraines and tension headaches. The underlying relationship between celiac disease and headache involvement is still unknown, but adherence to a gluten-free diet can alleviate neurological symptoms. Celiac disease can also cause cognitive impairment, including memory loss, clouded thinking, personality shifts, and an inability to calculate. Nutrient deficiencies, systemic inflammation, and low brain serotonin levels have been suggested as possible reasons for this. Celiac disease has also been associated with Alzheimer's and vascular and fronto-temporal dementias. Neuropsychological assessments should be conducted in celiac disease patients to assess cognitive function. Psychiatric Manifestations of Celiac Disease Celiac disease is associated with depression, anxiety, eating disorders, autism spectrum disorder, attention deficit hyperactivity disorder (ADHD), bipolar disorder, schizophrenia, and mood disorders. The relationship between celiac disease and these psychiatric disorders is not well-known or established. Particular biological aspects as well as the effect of a gluten-free diet require additional research. Depression and Anxiety Celiac disease has been associated with various psychiatric disorders such as depression, anxiety, eating disorders, autism spectrum disorder, attention deficit hyperactivity disorder (ADHD), bipolar disorder, schizophrenia, and mood disorders. However, the relationship between these disorders and celiac disease remains unclear and requires further research. Research suggests that gastrointestinal disorders have a link with depression and anxiety due to prolonged pain and inflammation, affecting specific brain targets like the anterior cingulate cortex. Gastrointestinal disorder patients have reduced cognitive and mood status, leading to anxio-depressive phenotypes, even in the absence of clear evidence of threats. Children with celiac disease may experience anxiety and depressive symptoms, and pediatric patients with celiac disease should be frequently assessed for mental health issues, especially anxiety and sadness. Adults with celiac disease have reported experiencing anxiety and depression as well, particularly due to clinical illnesses and symptoms. Following a gluten-free diet may worsen symptoms like anxiety and fatigue, leading to a diminished quality of life. Therefore, clinicians must recognize the importance of promoting both dietary adherence and social and emotional well-being in celiac disease patients. Studies have shown that individuals with celiac disease experience low quality of life, anxiety, and depressive symptoms, and nutrition plays a crucial role in reducing these effects. However, the role of motivation in the quality of life and adherence remains unclear and requires further research. Eating Disorders Eating disorders may be a comorbidity with celiac disease (celiac disease) and the need for further investigation. celiac disease patients may experience disordered eating due to the disease itself or other factors such as food neophobia. It is crucial for gastroenterology clinicians to be aware of potential risks for eating disorders in celiac disease patients. The article notes that while numerous examples of eating disorders have been described in celiac disease patients, few epidemiological studies have investigated this potential link. One study found that patients with celiac disease had higher Eating Attitude Test scores than controls when testing individuals aged 13 and up, but no clear differences were seen between patients with celiac disease and controls when using other screening measures for ED. The article suggests that further investigations with larger samples and prospective designs are needed to corroborate these results. The article also discusses how celiac disease may cause food neophobia, which is linked to sensory aversions or fears of the negative effects of eating particular foods. This fear may be more severe in celiac disease patients than in non-celiac disease patients who choose to follow a gluten-free diet and can be linked to the possibility of having an unfavorable reaction to gluten-contaminated food products. The article emphasizes the importance of gastroenterology clinicians being aware of potential risks for eating disorders in celiac disease patients. It notes that eating disorders are defined by thoughts and actions linked to physical and/or psychological problems and that it is crucial to identify past, current, and potential risks for eating disorders in celiac disease patients. Autism Disorder Autism spectrum disorder is caused by a complex interplay of genetic and environmental factors, affecting individuals in diverse ways. Recent studies suggest that immune system dysfunction could contribute to the development of autism spectrum disorder in some people [55]. While some research suggests a connection between celiac disease, an autoimmune disorder triggered by gluten consumption that mainly affects the small intestine, and autism spectrum disorder, other studies have not found a significant association between the two conditions. Attention Deficit Hyperactivity Disorder (ADHD) Research has suggested a potential link between celiac disease and ADHD, with studies showing that celiac disease is overrepresented in ADHD patients, and a gluten-free diet improved ADHD symptoms in celiac disease patients. However, routine screening for ADHD in people with celiac disease or vice versa is not recommended. Cognitive problems similar to those seen in children with ADHD, such as a lack of focus or trouble paying attention, were linked to gluten-free diet noncompliance in childhood celiac disease, as were psychosomatic symptoms and antisocial behavior. Individuals with untreated celiac disease may be at risk for engaging in ADHD-like behavior, specifically inattention. Out of 23 studies, 13 found a favorable correlation between ADHD and celiac disease. Bipolar Disorder Bipolar Disorders refer to a group of serious and long-term mental health conditions that are characterized by manic and depressive episodes. Research has shown that people with bipolar disorder have higher levels of immunoglobulin G (IgG) antibodies against gliadin than those without a history of psychiatric illness. However, there is still a need for further investigation into the specific antibody response to gluten antigens in bipolar disorder. Close associations have also been observed between celiac disease and major depressive disorder, panic disorder, and bipolar disorder, leading to reduced quality of life. Therefore, early reporting of symptoms and screening for celiac disease is recommended, especially for those with a family history of the disease or essential symptoms. Schizophrenia Schizophrenia is a severe mental illness that increases the risk of premature death 2-4 times compared to the general population. Genetic and environmental factors, including drug abuse, especially involving cannabis, are associated with an increased risk of developing schizophrenia. Research suggests an association between schizophrenia and celiac disease, although a causal link has yet to be established. Although having elevated antibodies against gliadin is a common immunological abnormality between schizophrenia and celiac disease, most patients with schizophrenia who had elevated anti-gliadin antibodies (AGA) did not have celiac disease. However, there is evidence that a gluten-restricted diet may benefit schizophrenia patients with immunological gluten sensitivity. One treatment-resistant schizophrenia patient with immunological gluten sensitivity benefited from a gluten-restricted diet improvement in both mental and physical symptoms, as well as a reduction in the plasma quantitative level of AGA-IgG. Chronic inflammation, which is thought to increase due to gluten intolerance, may worsen the symptoms of schizophrenia and make it harder for patients to respond to treatment and absorb medications. Schizophrenia patients also have a higher rate of digestive and liver problems. While removing gluten from the diet may alleviate some symptoms, it is not recommended for all patients. Gluten intolerance is believed to increase chronic inflammation, exacerbating symptoms and reducing medication absorption. However, the available data on the link between celiac disease, gluten allergies, and schizophrenia are inconsistent, and a gluten-free diet is not recommended for people with psychosis and mood disorders without further research. Other Psychiatric Disorders Previous research has shown that people with celiac disease are more likely to suffer from neuropsychiatric disorders than the general population. So far, more than 60 non-human leukocyte antigen (HLA) genes have been linked to celiac disease by genome-wide association studies; of these, it is believed that 15% have a role in neurological health. Many common neuropsychiatric disorders include celiac disease as a primary predisposing factor. It's possible that the co-occurrence of diseases is in large part due to shared molecular networks and biological processes. To determine what causes these disorders, we need to look at the underlying molecular mechanisms. Celiac disease was associated with an increased risk of psychiatric problems in children, raising their lifetime risk by 1.4 times that of the general population. Celiac disease in children has been linked to an increased likelihood of developing psychosocial difficulties later in life, including depression, anxiety, eating disorders, antisocial behavior, attention deficit hyperactivity disorder, autism spectrum disorder, and intellectual disability. It was also more common to have been diagnosed with a mood, eating, or behavioral condition prior to the celiac disease diagnosis. In contrast, no elevated risk was found for any of the psychological diseases studied in the siblings of people with celiac disease. A cohort study included nearly 20,000 children with biopsy-verified celiac disease, pairing each patient with 5 reference child controls. Approximately 16.5% of celiac children were diagnosed with a psychological condition during a median follow-up of 12.3 years, compared to 14.1% of controls. Celiac disease in childhood increased the risk of psychiatric illness by 19% and this risk increases during maturity, in particular, mood, anxiety, eating, ADHD, and autism spectrum problems. There was no statistically significant increase in psychotic disorders, psychoactive substance use, behavioral disorders, personality disorders, suicide attempts, or suicides. Celiac disease increases the use of psychiatric medication. Psychological issues associated with celiac disease were also more prevalent. As a result, the attending physician should conduct routine surveillance of potential psychiatric symptoms in patients of all ages who have gluten-related diseases, including both children and adults. Conclusions In conclusion, celiac disease has been linked to numerous neurological and psychiatric conditions, including depression, anxiety, eating disorders, autism spectrum disorder, attention deficit hyperactivity disorder (ADHD), bipolar disorder, schizophrenia, and mood disorders. Clinicians should assess mental health factors when making a celiac disease diagnosis. Overall, the relationship between celiac disease and these neurological and psychiatric disorders is not well-known or established. More research is needed to understand the pathophysiology of celiac disease's neurological and psychiatric manifestations. Particular biological aspects as well as the effect of a gluten-free diet require additional research. Read more at Cureus.com
  10. Celiac.com 09/26/2022 - Celiac disease is on the rise, and so are the gastrointestinal and other symptoms that go with it. A number of researchers have documented connections between various psychiatric disorders and celiac disease. However, the relationship between celiac disease, and such psychiatric disorders is not well studied or documented. A team of researchers recently set out to provide a greater understanding of the existing evidence and theories surrounding psychiatric manifestations of celiac disease. The research team included Emma Clappison, Marios Hadjivassiliou, and Panagiotis Zis. They are variously affiliated with the Medical School of the University of Sheffield, Sheffield, and the Academic Department of Neurosciences, Sheffield Teaching Hospitals NHS Foundation Trust and University of Sheffield, Sheffield. Their systematic review and meta-analysis appears in a special issue on gluten-related disorders, titled, Time to Move from Gut to Brain. The team conducted a search of online medical literature search using PubMed, pulling data on rates of celiac disease and psychiatric disorders from eligible articles. They then conducted a meta analysis of odds ratios. For their review, the team found a total of 37 articles that met their eligibility parameters. Compared with healthy controls, the team found people with celiac disease to have a significantly higher risk for autistic spectrum disorder, attention deficit hyperactivity disorder, depression, anxiety, and eating disorders. They found no significant differences for bipolar disorder or schizophrenia. The study revealed that celiac disease is associated with a higher risk of depression, anxiety, eating disorders, along with ASD and ADHD. The team is calling for more research into the specific biological reasons underpinning this connection, along with the potential benefits of a gluten free diet in improving these conditions. Read more in Nutrients 2020, 12(1), 142
  11. Celiac.com 07/06/2022 - More and more people are avoiding gluten and FODMAP food components (fermentable oligosaccharides, disaccharides, monosaccharides and polyols) over concerns about their potential connection to celiac-like reactions in the gut. In recent years, gluten-free diets (GFD) and low-FODMAP diets (LFD) have become more popular across the globe. This is due to intolerances or allergies in some people, but also due to the direct influence of marketing movements or diet trends on eating choices. At the same time, understanding, diagnosing and treating neurological and psychiatric diseases is becoming more important in numerous countries. A number of researchers have started to examine FODMAPs for that reason. Because of this, the research team conducted a bibliographic systematic review to see if there is a pathophysiological relationship between consumption of gluten or FODMAPs and mental disorders. The research team included Egoitz Aranburu; Silvia Matias; Edurne Simón; Idoia Larretxi; Olaia Martínez; María Ángeles Bustamante; María del Pilar Fernández-Gil; and Jonatan Miranda. They are variously affiliated with the Gluten Analysis Laboratory of the University of the Basque Country, Department of Nutrition and Food Science, University of the Basque Country in Vitoria, Spain; the GLUTEN3S Research Group, Department of Nutrition and Food Science, University of the Basque Country in Vitoria, Spain; the Bioaraba, Nutrición y Seguridad Alimentaria, in Vitoria, Spain; and the Centro Integral de Atención a Mayores San Prudencio in Vitoria-Gasteiz, Spain. The team's review gathered data from clinical and randomized controlled trials, based on the PRISMA statement, published since 2012. Their analysis found that limiting or ruling out gluten or FODMAPs may improve symptoms such as depression, anxiety, or cognition deficiency, and to a lesser extent for schizophrenia and the autism spectrum. Nevertheless, further studies are needed to obtain completely reliable conclusions. Read more in Nutrients 2021, 13(6), 1894.
  12. Good morning. I am new to this forum and am so glad to have found it. My mom (81) has moved in with me. She is a celiac, which we are doing well getting in a groove with that. My question is this, do any of you have a horrific cough? She has had every text under the sun completed with the final result being “allergy cough”. I’m leaning more towards anxiety. She coughs all day (I mean she really coughs to the point of loosing her breath) and all night...and has for years. Last night, when I climbed into bed with her, she stopped and didn’t cough for the rest of the night. Other little things I’ve started to pay more attention to makes me lean in this direction. Are any of you on a anxiety medication? If so, which one? Thank you!!
  13. I really need a better list of high Salicylate products. I use Tea Tree Oil on my face because it's the only thing that works on me for redness due to mites I'm apparently allergic to. Any way, I usually just use one drop in skin cleanser, but my cat jumped up right when I was using the dropper. Oops! Oh well, I went ahead and washed my face with it and wiped it off. Now my heart is pounding out of my chest and the anxiety is horrible. It always happens with Sals for me among other symptoms. Does anyone else have these symptoms with Sals? Also, I don't know how much Sals is in Tea Tree Oil, because of conflicting information. I know it wasn't what I ate because I been eating plain oatmeal and drinking water all week.
  14. Hey guys! I'm new to the gluten free lifestyle. It's been about 10 days and the dizziness anxiety and constant hunger are making me wanna loose my sh!t! Has anyone else experienced these symptoms after quitting gluten? I don't have tummy issues aside from the fact that I was backed up all of my life! Never thought it could be gluten because all I ever heard was diarrhea and stomach cramps. I would like to try exercising but I'm afraid the dizziness will get worse. From the research I've done these are all withdrawl symptoms but I'm hoping it doesn't last much longer because I do not take pharmaceuticals. The constant feeling of anxiety in my stomach tends to ease up a bit when I'm out of the house with other people but I'm mostly alone at home so it escalates. I meditate and ground and do qigong take deep breaths hot baths use essential oils drink herbal teas etc etc. So I'm exhausted and thinking it's just a matter of time.
  15. Hello, I recently got diagnosed with Celiac Disease around a month and half ago. I have been dealing with symptoms for two years (little did I know). When I was around 13, I started to gain a lot of weight out of nowhere, my hair started thinning and falling out, I developed a rash on my arms (Keratosis Pilarious), became very depressed and anxious constantly, had a never-ending stomach, became extremely tired all the time, and frankly never felt well. I had been dealing with minor knee problems up until this time but they quickly escalated due to the influx in weight and lack of muscle. i ended up having my first knee surgery in 7th grade. Meanwhile all of these symptoms were becoming more and more evident I was undergoing testing, where I was told it was all due to puberty. Heartbroken to know there was no answer to be given I had to except this new version of myself. Fast forward two years later where I was still dealing with the same problems, they did additional testing (only because my mother urged them to) and found I was iron deficient, however I was not anemic (hemoglobin was low but not terrible) even though I had .002 values. I started to take supplements and it made me sicker. Luckily for me my mother was relentless in finding an answer. We went to Vanderbilt and saw a Endocrinologist but once again my thyroid was in normal range. The next day I was scheduled for my second knee surgery which would be caused by an abundance of scar tissue caused by none other than inflammation. The doctor told me that I needed to go to a psychologist, which absolutely crushed me. I had no hope for ever getting any relief from not even one of my symptoms. My mother had other plans. She requested a Celiac panel, and the doctor clearly saw that as a psychotic move and wouldn't consider me for it because I am not underweight. The panel came back positive to my surprise, nevertheless there was the pandemic so naturally things took much longer to process. I was confirmed Celiac a month and 1/2 ago and I hope that some of what I am dealing with clears up. There is nothing like taking a shower and pulling out clumps of hair at age 15 and working out everyday and eating healthy for months and actually gaining weight. It definitely did a number on my self-confidence and mental stability. Let me know if this helps anyone or anyone has any advice for me! It would be much appreciated, I am still very new to this. Moral of the story: do not give up on yourself just because your doctors have.
  16. Celiac.com 08/27/2021 - Like most celiacs, my social life was eclipsed by strict new rules following diagnosis. At the age of 22, I could be seen, as often as not, with one hand over a pint glass and the other in a communal snack bowl. Shortly after my 23rd birthday, however, I was informed by my specialist that I had celiac disease. This meant a lifelong diet without wheat, rye, or barley. “So, like, you mean no beer, bread, or pasta, right doc?” It seemed like a small freedom to sacrifice for protection from the intense discomfort I’d been experiencing. It wasn’t until I visited a dietitian that my life was violently overtaken by one word: cross-contamination. This new despot threatened my public and private life. For the following year, no door handle, remote control, or receipt was touched without a slight rise of panic. I understand that gluten cannot be absorbed through the skin but once something is on your hands, it’s not too long until it has a chance to be ingested, be it through a brush of your nose, grabbing a snack on-the-go, or, as is a nervous behavior of mine, picking at dry bits of skin on my lips (disgusting, I know). The kitchen I shared with my non-celiac roommate soon became a center of stress and anxiety. Each time I entered, I visualized those mischievous little protein molecules crawling on everything. Preparing any meal involved washing my hands about five times: 1) Opened the fridge to get out vegetables, contaminated fridge door, must wash hands; 2) opened the drawer to get out knife to cut vegetables, contaminated drawer handle, must wash hands; etc. My knuckles became as red and cracked as a sailor’s. Nearly every day I envisioned a new way in which my food might become contaminated. This added mile seemed to push recovery and good health further away. The check-out counter at the grocery store; assignments from my students—zealous consumers of powder-flavored, prepackaged snacks; and who’s to say that some sandwich-loving employee at the coffee plant would always wash her or his hands after each bagel break? I even had anxiety attacks when my most conscientious friends and relatives cooked for me. In retrospect, I’m grateful amicable relations survived my leery stares over the shoulders of unfortunate hosts. My own kitchen was also turned into a tightly-controlled operation, where I made my roommate and houseguests quake at the mere thought of straying from the line. The anxiety about people touching my food and dishes with their contaminated hands caused me to bark rules at house guests before they’d so much as taken off their shoes. My party-girl personality was eradicated by the new prudish and intolerant ideology. For one thing, I could no longer consume in ignorance. I had to know exactly what I was putting in my body (“What’s in this shot?” “Uh….I dunno…vodka and some other stuff” “Sounds good.”). My inability to be laid back about alcohol crossed over into an inability to be laid back and fun-loving in general. A watchful eye was forever darkening my thoughts. I’d order a gin and soda, thinking it was safe, and my spirit would become crushed like the lime the bartender, hands covered in beer suds, squeezed onto the rim of the glass. I began to favour staying within the regulated confines of my own home. Whispers of “neurotic,” “controlling,” and “lunatic” threatened a rebellion against my methods of control. Although my particular neurosis has yet to be categorized and defined, the obvious parallel is germaphobia. I did some elementary research into this disorder and gained a little insight through the help of my good friend, Wikipedia, ( It is by no means definitive but a great starting point). It lists the following characteristics of germaphobes: Obsessive washing, such as repeated hand washing. Avoidance of activities that involve uncleanliness. Makes well-known their unwillingness to share food, utensils, and other personal items, even when unasked. Any of this sound familiar? I had to admit it. I was gluten-phobic. There are still times I’d like to crawl inside a gluten-proof bubble. The benefits of being isolated from gluten seem to far outweigh the benefits of being integrated into society. As yet, however, there is no such option for us Howard Hughes’ of the celiac world. The unfortunate thing for celiacs is that, to a certain extent, we have to be gluten-phobic. Unlike ingesting germs, which may or may not make a person ill, ingesting gluten will almost definitely cause us harm. Furthermore, many people argue that exposure to common germs and viruses is necessary to build a strong immune system, whereas the prevalent medical argument of today is that celiacs should not try to build up even a small amount of gluten tolerance. Yet, if we are to continue to live in a gluten-consuming society, we must not let fear dictate our lives. Family, friends, co-workers, and roommates must adapt to the rules we have no choice about. Some individuals are frustratingly slow to catch on. A few are inevitably condemned to exile. Fortunately, there are others who can adapt to our way of life here in celiac country. My problem was that I needed to trust these allies, to help them learn our customs by being positive, patient, and encouraging rather than through paranoia. My new roommate and I are hosting a New Year’s party. We are hoping to squeeze at least fifty inebriated friends into our cozy apartment. When the subject of snacks was discussed with our friends, people began offering their cooking services. One woman was titillated at the prospect of making her favorite guilty-pleasure snack: cheese whiz on toast with bacon bits. I’d already begun fretting over errant drippings of beer foam. Now, I pictured jovial, uninhibited, crumb-covered hands searching through cupboards, contaminating dishes and food products, leaving gluten-y traces on bottles of lotion and lipstick in the bathroom. I became so filled with worry that I eventually broached the subject with my roommate. It was difficult to voice my concerns, because I hate feeling like an inflexible militia-leader. For the sake of my roommate, family, and friends, I don’t want to implement a regime of fear-induced adherence to strict anti-gluten measures. I want my home to feel relaxed rather than tense. A compromise was reached: our invitations read, “B.Y.O.B. Snacks provided.” Yes, more than one sudsy bottle will likely overflow. I console myself with the fact that, just as black must live with white, Christian with Hindu with Buddhist with Muslim with Jew, heterosexual with homosexual, so must we gluten-intolerant live side by side with beer-guzzling bread eaters. When I think of my wonderful friends and relatives, I wouldn’t have it any other way.
  17. Celiac.com 02/15/2021 - A number of studies have tied celiac disease to psychiatric disorders, but there is still not much good data to support the connection. To get a better picture of the issue, a team of researchers recently set out to describe the epidemiology of several psychiatric disorders in celiac disease. The research team included Motasem Alkhayyat, Thabet Qapaja, Manik Aggarwal, Ashraf Almomani, Mohammad Abureesh, Omaymah Al‐otoom, Mohammad Zmaili, Emad Mansoor, and Mohannad Abou Saleh. They are variously affiliated with the Department of Gastroenterology, Hepatology, and Nutrition, Cleveland Clinic Foundation, Cleveland, Ohio; the Department of Internal Medicine, Cleveland Clinic Foundation, Cleveland, Ohio; the Department of Gastroenterology, University Hospitals Cleveland Medical Center, Cleveland, Ohio; the Department of Internal Medicine, University Hospitals Cleveland Medical Center, Cleveland, Ohio; University of Jordan Medical School, University of Jordan, Amman, Jordan; and Department of Internal Medicine, Staten Island University Hospital, New York City, New York. For their study, the team used a multi‐center database, called Explorys Inc, which offers electronic health record data from 26 major integrated healthcare systems consisting of 360 hospitals in the US. Of the 3,746,581 patients in the database between 2016‐2020, there were 112,340 patients with celiac disease. The team identified a group with celiac disease using the Systematized Nomenclature Of Medicine ‐ Clinical Terms (SNOMED–CT). They then conducted multivariate analysis using SPSS version 25. Compared to patients with no history of celiac disease, celiac patients were more likely to have a history of anxiety, depression, bipolar, ADHD, eating disorder, and autistic disorder. Patients with celiac disease and psychiatric conditions were more likely to be smokers, and to have a history of alcohol and substance abuse , along with a history of personality disorder. This large database study shows that celiac patients have a higher risk of having multiple psychiatric diseases including anxiety, depression, bipolar, ADHD, eating disorder, and autism. The team advises clinicians to keep mental health in mind when treating celiac patients, and to make psychiatric referrals as needed. Read more in Gastroenterology
  18. Celiac.com 06/29/2020 - Coronavirus Disease 2019 (Covid-19) has killed nearly a half a million people globally, and over 120,000 here in the United States. People with celiac disease have to eat gluten-free in order to avoid negative health consequences. The pandemic fallout has included home lockdowns, food shortages, and disruptions. How concerned and/or anxious are people with celiac disease about the lockdowns and the possible shortages of gluten-free food? A team of researchers recently set out to to evaluate the perception of this in celiac disease patients who require a lifelong gluten-free diet as a therapy. The research team included Monica Siniscalchi, Fabiana Zingone, Edoardo Vincenzo Savarino, Anna D'Odorico, and Carolina Ciaccia. They are variously affiliated with the Celiac Center at Department of Medicine, Surgery, Dentistry of the Scuola Medica Salernitana at the University of Salerno in Salerno, Italy, and the Gastroenterology Unit of the Department of Surgery, Oncology and Gastroenterology at University of Padua in Padua, Italy. To get a picture of the concerns people with celiac disease are having during the pandemic, the team created an e-mail COVID-19 survey for adult patients from the University of Salerno in Campania, in the south of Italy, and the University of Padua in Venice, in northern Italy. After emailing 651 surveys to adult celiac patients, the team received 276 replies, for a response rate of just over 42%. Nearly 60% of celiacs said that they were not concerned about being more susceptible to Covid-19 just because they had celiac disease. Nearly 50% said that they were not concerned "at all" about the possible gluten-free food shortages during the pandemic. Of patients who were concerned about exposure and food shortages, most were older, female, and suffered from other comorbidities. Finally, celiac patients said that they were happy with remote consultations and explicitly asked to have them. The researchers point out that COVID-19 offers clinicians a chance to practice large-scale remote consultation for providing healthcare for people with celiac disease. According to the researchers, telemedicine is popular with celiacs, and should be integrated into the celiac healthcare regimen. The COVID-19 pandemic has affected numerous celiac patients, especially women, elderly patients, and those with comorbidities. Read more in Dig Liver Dis. 2020 May 16
  19. Celiac.com 08/25/2020 - A number of studies describe psychological disorders, in addition to other extra intestinal manifestations of celiac disease, such as fatigue, neurological conditions including headache and neuropathy. However, there hasn't been study with robust enough data to provide accurate risk estimates. In an effort to obtain accurate risk estimates, Jonas F. Ludvigsson, MD, PhD, of the department of medical epidemiology and biostatistics at Karolinska Institutet in Sweden, and colleagues analyzed data from the Swedish nationwide ESPRESSO cohort to explore associations between childhood celiac disease and psychiatric disorders. They matched nearly 20,000 children with biopsy verified celiac with up to five of 100,000 reference children, and gathered data on psychiatric disorders from the patient register. During a follow-up period of just over 12 years, nearly 17% of 3,174 children with celiac disease were diagnosed with a psychiatric disorder, compared with about 14% of the 13,286 control subjects. People with childhood celiac disease had a nearly 20% increase in risk for any psychiatric disorder, an increase seen in every childhood age group. Specifically, celiac patients faced elevated risks for mood disorders, anxiety disorders, eating disorders, attention deficit hyperactivity disorder, autism spectrum disorder, and increased use of psychiatric drugs. The risk was highest in the first year after celiac diagnosis, but continued into adulthood. The results of this study underline the importance of mental health monitoring in people diagnosed with celiac disease as children. Because of the elevated risk of psychiatric disorder, the team advises that people diagnosed with celiac disease in childhood receive both physical and mental monitoring into adulthood. Stay tuned for more on this and related stories. Read more at Healio.com.
  20. Hello everyone, I went gluten free before 6 months after 2 years of many symptoms. I am not celiac, biopsy revealed chronic inflammation. I tested positive for SIBO but decided not to take antibiotics for it as I was not convinced of the test results. I went to a functional medicine doctor and my symptoms improved after elimination diet for 45 days where I stopped eating top 8 allergens. I was able to eat eggs, dairy and nuts for couple of months. Now I feel very anxious and depressed after eating eggs and nuts. And my feets are also burning like before. Anyone experienced this? I am clueless on what to do, I am planning to eliminate foods again. Any pointers would be very helpful.
  21. Hi All, I was diagnosed with celiac about 4 months ago and am having persisting symptoms. I'm looking for some advice. Since January of this year I was having gastrological symptoms (sharp abdominal pain after consuming gluten or acidic foods, constipation, acid reflux, bloating, mild weight gain). Throughout the year I noticed other symptoms like face puffiness, especially around my eyes, mouth, and under my chin. I went gluten free in June because I realized it alleviated some intestinal symptoms. They tried to give me omeprazole for the acid reflux but it made me very nauseous so I stopped. I also found out I was anemic and began taking iron supplements. In August I went back on a gluten diet for two weeks in order to have the celiac blood test, which came back positive. The next available appointment for an endoscopy/biopsy wasn't until November and my doctor said I could remain gluten-free because it would put me in too much pain, but that it may cause a false negative in the biopsy. So I decided to act as if I had celiac-- I stuck to a VERY strict gluten-free diet and started to really pay attention to cross-contamination. I got all new cookware, etc. However, at that point a whole host of other symptoms began, mostly neurological. I started getting debilitating brain fog (like I couldn't think clearly at all, couldn't pay attention, felt brain dead), my anxiety and depression went through the roof, I felt dizzy constantly (like the room was spinning), headaches, fatigue. The intestinal symptoms got better-- no more sharp pain, no acid reflux unless I got gluten sick, less bloating. My skin and face also began to suffer-- it started looking dull and sagging like I was aging (I'm 24 and otherwise healthy), acne got worse, my face was more swelled than before, my eyelids started drooping (the left one droops all the way to my eyelashes). But the neurological symptoms were the most difficult to endure because it made functioning in daily life almost impossible. I suspected a thyroid issue and got that tested but the results were normal. I finally had my endoscopy and the biopsy results were negative other than some "mild chronic inflammation." Slowly over the course of 4 months there has been some improvement (my face looks less puffy some days/acne has cleared up), my dizziness is better but still persistent, my brain is still foggy but better than before. My first clue to getting gluten cross-contaminated is a bout of dizziness followed by a panic attack and acid reflux, constipation the next day, and pretty bad brain fog for a few days until I level off. I have little to no other gastrological symptoms. Despite being better than before, I still haven't felt "normal" in 4 months since August. I had been feeling like I was improving slightly but recently I feel like it's leveling off and I'm stuck at this half-sick stage. I am very strict with my eating habits and I eat mostly vegetables and meat. I exercise multiple days a week. I don't understand why these neurological symptoms came on so suddenly when I had already been on a gluten-free diet for a few months... I don't understand why I'm not getting better. When I consulted my doctor about this she said I might be having physical manifestations of anxiety/depression (since they came on so quickly after I was formally diagnosed and that could've triggered it). But I feel like there is more going on in my body. I just want to feel like a normally functioning human again. So I'm asking for some advice on what to do next? Why am I not improving? Do I just need to give it more time? Any other tests I could be taking to see if something else is going on? My doctors have been so unhelpful. Thank you!
  22. Celiac.com 05/02/2019 - Both gastrointestinal and mental disorders can occur alongside other disorders, and both can be triggered by early adversity, such as parental deprivation. Interactions between the brain and bacteria that live in the gut microbiome potentially influence interactions between adversity, gastrointestinal issues and anxiety. These connections have been well-studied in animals, but very little study has been done during human development. What can we learn about mood and gastrointestinal distress in children exposed to adversity? A team of researchers recently set out to explore adversity–gastrointestinal–anxiety associations in youth who were raised with their biological parents, or were exposed to early adverse care giving experiences, such as institutional or foster care followed by international adoption. The research team included Bridget L. Callaghan, Andrea Fields, Dylan G. Gee, Laurel Gabard-Durnam, Christina Caldera, Kathryn L. Humphreys, Bonnie Goff, Jessica Flannery, Eva H. Telzer, Mor Shapiro and Nim Tottenham. To assess connections between adversity, gastrointestinal issues, and anxiety, the team assessed data from a 344 youth, aged from 3–18 years old, who were raised with biological parents, or else exposed to early adverse care giving experiences, such as institutional or foster care followed by international adoption. In Study 1, we demonstrated that previous adverse care experiences were associated with increased incidence of gastrointestinal symptoms in youth. Gastrointestinal symptoms were also associated with concurrent and future anxiety (measured across 5 years), and those gastrointestinal symptoms mediated the adversity–anxiety association at Time 1. Study 2 comprised a sub-sample of children who provided both stool samples and functional magnetic resonance imaging of the brain, and served as a “proof-of-principle." The data from study 2 showed that adversity was tied to changes in both alpha and beta diversity of microbial communities, and both adversity-associated and adversity-independent bacteria level correlated with prefrontal cortex activation to emotional faces. Read more about the implications of these data for supporting youth mental health at Cambridge.org The researchers are variously affiliated with the Department of Psychology, Columbia University in New York, NY; the Department of Psychiatry, Melbourne University, Melbourne, Australia; the Department of Psychology, Yale University in New Haven, CT; Harvard Medical School, Boston, MA, USA; the Semel Institute for Neuroscience and Human Behavior at the University of California Los Angeles in Los Angeles; the Department of Psychology and Human Development at Vanderbilt University in Nashville, TN, USA; the Department of Psychology, University of California, Los Angeles, Los Angeles, CA, USA; the Department of Psychology at the University of Oregon in Eugene, OR; the Department of Psychology and Neuroscience at the University of North Carolina, Chapel Hill, in Chapel Hill, NC; and the David Geffen School of Medicine, University of California, Los Angeles in Los Angeles, CA.
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