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Jefferson Adams posted an article in Celiac Disease & Gluten Intolerance ResearchCeliac.com 06/19/2018 - Could baking soda help reduce the inflammation and damage caused by autoimmune diseases like rheumatoid arthritis, and celiac disease? Scientists at the Medical College of Georgia at Augusta University say that a daily dose of baking soda may in fact help reduce inflammation and damage caused by autoimmune diseases like rheumatoid arthritis, and celiac disease. Those scientists recently gathered some of the first evidence to show that cheap, over-the-counter antacids can prompt the spleen to promote an anti-inflammatory environment that could be helpful in combating inflammatory disease. A type of cell called mesothelial cells line our body cavities, like the digestive tract. They have little fingers, called microvilli, that sense the environment, and warn the organs they cover that there is an invader and an immune response is needed. The team’s data shows that when rats or healthy people drink a solution of baking soda, the stomach makes more acid, which causes mesothelial cells on the outside of the spleen to tell the spleen to go easy on the immune response. "It's most likely a hamburger not a bacterial infection," is basically the message, says Dr. Paul O'Connor, renal physiologist in the MCG Department of Physiology at Augusta University and the study's corresponding author. That message, which is transmitted with help from a chemical messenger called acetylcholine, seems to encourage the gut to shift against inflammation, say the scientists. In patients who drank water with baking soda for two weeks, immune cells called macrophages, shifted from primarily those that promote inflammation, called M1, to those that reduce it, called M2. "The shift from inflammatory to an anti-inflammatory profile is happening everywhere," O'Connor says. "We saw it in the kidneys, we saw it in the spleen, now we see it in the peripheral blood." O'Connor hopes drinking baking soda can one day produce similar results for people with autoimmune disease. "You are not really turning anything off or on, you are just pushing it toward one side by giving an anti-inflammatory stimulus," he says, in this case, away from harmful inflammation. "It's potentially a really safe way to treat inflammatory disease." The research was funded by the National Institutes of Health. Read more at: Sciencedaily.com
mbaxter2 posted a topic in Celiac Disease - Pre-Diagnosis, Testing & SymptomsI have suspected I have celiac disease (or at the very least am gluten-intolerant) for several years. I know very little about this disease and the more I learn the more confused I get. There is still so much more to learn and I feel overwhelmed reading about it. A few years ago, I read Elisabeth Hasslebeck’s book (I think it’s called the gluten-free Diet?) and was pretty convinced I had this disease. I just thought ok well one day I will get tested for it and deal with it then. Honestly, I did not want to have it. I read about all that you CANNOT eat and it sounded awful. So, I just put it out of my mind and thought to myself I probably don’t have it anyway. I have suffered from gastrointestinal problems since I can remember. My main issues are constipation, bloating, horrible abdominal pains, and every now and then nausea. I sometimes feel a sharp pain under my left rib cage. Sometimes the bloating and uncomfortable abdominal pain hurts so bad it hurts to move and I have to unbutton my jeans in order to ease the pain. Sometimes I have painful diarrhea after a particularily fatty meaI. I have tried loading up on fiber and water to help with the constipation. I have tried drinking Miralax. I have eaten prunes, drank prune juice, eaten 25 grams of fiber a day (along with lots of water), drank green smoothies, and just about all that is suggested. Nothing ever helps. I have accepted that this is just how my body is and I will “go when I go”. If I go days without a bowel movement I will take a laxative, which helps, although there have been times it didn’t. I have also used suppositories and enemas (both working most of the time, however, there have been times when no bowel movement was produced). Last year I was having shooting, stabbing pains in my tummy and a friend rushed to the store to get an enema. I layed on the bathroom floor until she came back because it hurt to move. I am currently suffering from tummy issues (as usual) and today I randomly looked celiac up online again. I am once again convinced I have this. I just discovered that iron-deficiency anemia is often linked to celiac disease and that Candida is linked to celiac disease as well. Here is some background info: 1. Had surgery when I was 2 years old due to a hernia. My mom says that from then on I had issues with my bowels. I have read that stress or surgery can trigger or cause celiac disease. 2. Had bad yeast infections since I was a little girl. As an adult I asked the gyno what made me get them so often and she told me that some women are just more prone to them. 3. Diagnosed with IBS when I was 18 years old. 4. Diagnosed with an auto-immune disease when I was 20 years old. (It is a rare disease called henoch-scholein purpura and attacks the kidneys) 5. Diagnosed with hypothyroidism last fall. The doctor told me she wanted to wait and see if my thyroid would get better on its own because once I start the hormone replacement I will have to take it forever. 6. Diagnosed with iron-deficiency anemia and started on Ferro-sequels, a potent iron supplement. I was happy to discover I was anemic because I was horribly fatigued and it gave me an explanation as to why. (I was also deficient in vitamin D, but I think this is pretty common?) 7. Auto-immune diseases run in my family (my grandma has Addison’s disease, cousin has thyroid disease, multiple sclerosis, etc) Can anyone relate to this or give me any insight? What is the likelihood that I have celiac disease? I have not lost weight, if anything I cannot lose weight. From what I've read constipation isn't common with celiac, it is usually the opposite (having to go too much). I am going to have blood work done in a few weeks and am thinking about requesting to be tested for celiac disease. My only reservation is the cost of the additional tests (I do not have insurance and am paying out of pocket). Also, from what I have read, false-negatives are common for celiac disease so should I even bother with spending money on the test right now? Should I just go gluten-free and see how I feel? I know that if I should NOT go gluten-free if I do decide to have the test done, as this can affect the accuracy of the results. I will definitely have the test done at some point, just trying to figure out if I should pay out of pocket right now or wait a year until I have insurance. Any suggestions would be extremely appreciated. The more I learn about celiac disease the more questions I have. I know there is so much more for me to learn and I will continue to do research. Thank you! Meagan