Search the Community
Showing results for tags 'autoimmune disease'.
Found 4 results
Jefferson Adams posted an article in Celiac Disease & Gluten Intolerance ResearchCeliac.com 04/25/2018 - A team of Yale University researchers discovered that bacteria in the small intestine can travel to other organs and trigger an autoimmune response. In this case, they looked at Enterococcus gallinarum, which can travel beyond the gut to the spleen, lymph nodes, and liver. The research could be helpful for treating type 1 diabetes, lupus, and celiac disease. In autoimmune diseases, such as type 1 diabetes, lupus, and celiac disease, the body’s immune system mistakenly attacks healthy cells and tissues. Autoimmune disease affects nearly 24 million people in the United States. In their study, a team of Yale University researchers discovered that bacteria in the small intestine can travel to other organs and trigger an autoimmune response. In this case, they looked at Enterococcus gallinarum, which can travel beyond the gut to the spleen, lymph nodes, and liver. They found that E. gallinarum triggered an autoimmune response in the mice when it traveled beyond the gut. They also found that the response can be countered by using antibiotics or vaccines to suppress the autoimmune reaction and prevent the bacterium from growing. The researchers were able to duplicate this mechanism using cultured human liver cells, and they also found the bacteria E. gallinarum in the livers of people with autoimmune disease. The team found that administering an antibiotic or vaccine to target E. gallinarum suppressed the autoimmune reaction in the mice and prevented the bacterium from growing. "When we blocked the pathway leading to inflammation," says senior study author Martin Kriegel, "we could reverse the effect of this bug on autoimmunity." Team research team plans to further investigate the biological mechanisms that are associated with E. gallinarum, along with the potential implications for systemic lupus and autoimmune liver disease. This study indicates that gut bacteria may be the key to treating chronic autoimmune conditions such as systemic lupus and autoimmune liver disease. Numerous autoimmune conditions have been linked to gut bacteria. Read the full study in Science.
squirmingitch posted a topic in Celiac Disease - Publications & PublicityUniversity of Bristol press release 9/3/14 Read the article: http://www.bris.ac.uk/news/2014/september/autoimmune-disease.html
No one besides me has been checked or diagnosed with Celiac's Disease. My mother has hypothyroid (poorly managed-not sure if it's Hashi or not) and EoE (eosinophilic esophagitis) also poorly managed. She has had to have her esophagus dilated 3x now. It is ridiculous that the only therapy that they have offered is steroids and acid reflux medication. I *finally* convinced her to get tested for Celiac Disease (I have told everyone in my immediate family to be screened). She has an appointment with her gastroenterologist next Tuesday. I told her to request a Celiac Panel to check her antibodies. Hopefully we can get to the root of this issue. She has had other signalments of celiac disease as well including: headaches, hair loss, skin rashes, extreme fatigue, nerve issues, weight gain/bloat, constipation. If it is not gluten that is her trigger, I sincerely hope she starts a dietary elimination trial starting with dairy products. Is there anything else I need to tell her or have her request of her doctor next week? Also - unless her doctor specifically tells her to stop eating gluten she won't.. and she won't listen to me. She is stubborn stubborn stubborn!!!
runsuzannerun posted a topic in Celiac Disease - Pre-Diagnosis, Testing & SymptomsI am an emerging professional distance runner and have suffered from all of the celiac symptoms in the book. I have also had hypothyroidism for about 12 years and have had to increase my dose after every visit due to malabsorption. My symptoms started about 3 years ago when I started running and were almost unbearable, and I have also been suffering from anemia. I only became aware of celiac disease after another runner suffering from the same symptoms was diagnosed. Not knowing much about it, I skipped the blood tests and went straight to the GI. The nurse practioner said it sounded like classic celiac and had no problem getting me in for the endoscopy. When I went in for the procedure, the official "doctor" asked me what my problems were. I told him that I am convinced I had celiac disease, and his reply was, "you don't have celiac." This really concerned me, but I was already hooked up to the IV and prepped. When I called for my results, they said that they were negative, but they found some redness and chronic inflammation that was from gastritis. They said I should come back in for a follow-up and think about getting a colonoscopy. Completely unconvinced and frustrated, I asked to see the results for myself. They sent me the actual pictures from the biopsy, and I spent hours comparing them to other biopsies of people with celiac disease. Clearly, I am not a doctor, but my biopsies looked identical to other biopsies with a celiac disease diagnosis! The vili are definitely blunted and much shorter than they should be. I self-diagnosed myself with celiac disease and went gluten-free for what's been 4 months now. I started feeling almost 100% better after about a month, but now I am having some other problems that are representing a hyperthyroid. I feel that my gut is able to absorb my synthroid much better now, that I am actually overmedicated. This has now brought me back to the frustration of getting the proper diagnosis for celiac disease and seeing a doctor who actually knows about the connection between celiac disease and other autoimmune disorders such as Thyroiditis. I feel really helpless and am looking for some advice as to who I should see. I live in the San Diego area and would appreciate any feedback. Is it possible to just take my biopsy results to another doctor? Please help!