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Found 5 results

  1. Hi, it's me again. A quick question for you guys! Im waiting to see a gastro in June, but as symptoms have been almost unbearable, i decided to do a DNA test in the interim to see if I had the hladq2 or hladq8 markers. Got the results back a couple days ago, and i have neither of those markers, and have been told i have a low risk of developing the disease. What I would like to know is this, can you test negative for the dq2/dq8 markers and still go on to develop celiac disease? Any thoughts, opinions etc would be very appreciated! Thank you
  2. Hello! I'm new to joining but have found a lot of helpful info here. I'm hoping I can get some help understanding these SNPs? I did 23 and me and I'm a little confused. I searched for these SNPs in my data (per an article online) and am still a little unsure of their link to celiac? I've been gluten free for a few months and really, truly don't want to do a gluten challenge but still hopeful for maybe a little insight from DNA. Does simply having them mean something or just the allele results? rs3184504 T/T rs2187668 G/G rs7454108 T/T
  3. I had a celiac blood test around may 2015. I'm 20, male. AGA - 35 range 0-20 TTG IgA - 5 range 0-20 I believe total IgA was normal. I have been gluten free, avoiding gluten best I could for about 2 weeks before this. On june 2015, did a biopsy, results said no signs of villous atrophy, doctor convinced I don't have it. Been gluten free for about a month before this, doctor only said to eat a 'normal' diet beforehand. I know that this could yield false negative results, but I don't think the amount of time is enough to hide the damage? Had symptoms since I was 4-5 years old, very skinny , pale, constipation, diarrhea, inconsistent nausea (from eating wheat products, soy sauce), migraines, stomachaches, night terrors, sleepwalking. Symptoms were most evident till around 10 years of age. During my teens, the symptoms seemingly start to fade, rarely nauseated, random bouts of diarrhea 1-2 times a month or so. Been gluten free for up to 8 months now, decided to start eating gluten again just to see how I would feel/ for retesting. Almost on day 2, no noticeable symptoms. Ate gluten heavy for a month, a year before, breads, pasta 2-3 times a day, lost over 3-4 kg, started feeling overly lethargic during the day/after eating gluten. Sharp stomach pains and mild diarrhea once or twice. I'm quite certain it's celiac, but if its not, and after reading about how non celiac gluten sensitivity might not exist,i don't really know what to think anymore. Any opinions/ similar experiences would be appreciated.
  4. Hi all: I've been lurking here for about a month and finally decided to post. Thinking I may have a problem with gluten sensitivity, I did the Enterolab "poop" test (really gross, but had quite the laugh in the car on the way to UPS, wondering if they would ask me if I wanted to insure the contents! ). Here are my results: Fecal Anti-gliadin IgA 71 Units Fecal Anti-casein (cow’s milk) IgA 31 Units Fecal Anti-ovalbumin (chicken egg) IgA 9 Units Fecal Anti-soy IgA 13 Units Because anything over 10 is outside the normal range, I show sensitivities to gluten, casein, and soy. Then they checked my fat malabsorption: Quantitative Microscopic Fecal Fat Score 1288 Units Anything over 300 is outside the normal range, with over 1000 being in the severe range. Wow!! Finally, I had my gene panel done: HLA-DQB1 Molecular analysis, Allele 1 0301 HLA-DQB1 Molecular analysis, Allele 2 0501 Serologic equivalent: HLA-DQ 3,1 (Subtype 7,5) No DQ2 or DQ8, but two gluten sensitivity genes, one of them a DQ7 which has been implicated in a low percentage of celiac cases. Here's a history of medical problems I've had over the years, many of which I've seen reported as correlaeted with celiac disease:: Bedwetter till age 12 (so were my sister and brother) Very irregular menstrual cycles Chronic UTI Fibromyalgia Seborrheic dermatitis (severe) - started with "cradle cap" as an infant Mouth sores Episodes of tingling and numbness Obesity since age 9 Diarrhea/Constipation/Stomach upset Frequent eye twitching Rosacea Severe hay fever Heart palpitations Costochondritis Kidney stones Gallstones Diverticulosis with 3 episodes of diverticulitis Migraine headaches Leukocytoclastic vasculitis (also known as cutaneous vasculitis), an autoimmune disorder Possible Sjogren's - rheumatologist did not test for it, but believes it's likely, although I'm not so sure I'm thinking I may be one of the few celiac patients without DQ2 or DQ8. I cannot have blood testing done because I've been gluten free and dairy free for about six weeks and have no desire to do a gluten challenge. I am feeling significantly better off gluten -- fibromyalgia pain is essentially gone, knees don't hurt, SD has cleared up, heart palpitations have slowed down, hay fever is reduced, UTI's have decreased, and I've lost about 13 pounds. What do y'all think?
  5. Hi, I am new here. My 5 yr old son was negative for all celiac disease bloodwork in 2010 and July 2012. He used to have mild GI symptoms that improved drastically after determining he is lactose intolerant, but he still had some ongoing, occassional issues until I realized that he also has an issue with fructose. I'm happy to report that since I started limiting his fructose intake in August, all of his symptoms have completely resolved and he is doing well, gaining weight, and growing I should mention that he was borderline anemic in July (10.8hgb) that has gone up to 12.2 with a low dose iron supplement. Likewise, since I started limiting his fructose, his appetite has increased tenfold (he never was hungry before!) and he is the happiest I've ever seen him. All of this has really made me believe in the fructose malabsorption diagnosis. We have seen 2 GIs (NJ/NYC) and both were not concerned with celiac disease any longer; they felt we had ruled that out. Both agreed that if I saw complete resolution of symptoms with the new low fructose diet, that is it. However, my pediatrician decided to throw a wrench in the works and said, "Why don't we do the DNA testing for celiac disease? It will show us for certain that he doesn't have the gene and you can forget about it." Well, now I get these results. And of course, the pediatrican doesn't know how to interpret them other than to read the paper to me and tell me that not everyone with the gene will get celiac disease. I'd also like to know what these results may mean for my other 2 children (healthy). Please help! I'm waiting to hear from the specialist. Thank you so much in advance. Lab Corp results: Celiac HLA-DQ Result DQ Alpha 1 01, 03 DQ Beta 1 03:02, 05 Interpretation: These genes are permissive for celiac disease. The absence of HLA celiac permissive genes would make the presence of celiac disease unlikely. However, these genes can also be present in the normal population.