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Celiac Category 4 (NOTE) CATEGORY DQ HAPLOTYPE RELATIVE RISK Category 7 DQ2.2 AND DQ2.5 Extremely High Category 7 DQ2.5 AND DQ2.5 Extremely High Category 6 DQ2.2 AND DQA1*05, DQB1*03:01 Very High Category 5 DQ2.2 AND DQ8 Very High Category 5 DQ2.5 AND DQ8 Very High Category 4 DQ8 AND DQ8 High Category 3 DQ2.5 AND DQA1*05, DQB1*03:01 High Category 3 DQ2.5 AND DQA1*03, DQB1*02 High Category 3 DQ2.5 AND OTHER LOW RISK ALLELE High Category 3 DQ2.2 AND DQA1*05, DQB1*03:03 High Category 2 DQ8 AND OTHER LOW RISK ALLELE Moderate Category 1 DQ2.2 AND OTHER LOW RISK ALLELE Low Category 0 NEGATIVE FOR DQ2.2 Negative Category 0 NEGATIVE FOR DQ2.5 Negative Category 0 NEGATIVE FOR DQ8 Negative DQ2.2 = DQA1*02:01, DQB1*02:02 DQ2.5 = DQA1*05, DQB1*02:01 DQ8 = DQA1*03, DQB1*03:02 The identification of o ne of these HLA-DQ genotypes is not, by itself, sufficient for the diagnosis of celiac disease, since both DQ2 and DQ8 are relatively common in the general population. Hi friends. I was tested last year as I had very severe bloating problems and after lots of searching and adking around on the internet, someone informed me it may be celiac. Every doctor I have seen so far has brushed it off, I don't have it blablabla. I didn't believe them, couldn't afford to visit with a GI doc, and definitely couldn't afford the endoscopy. Also I have been thinking as this has been relatively new, and inconsistent- perhaps my intestines wouldn't have such a visible difference at this point. I was gluten-free for weeks, then succumbed to everyone telling me "it's not Celiac!! nobody really has it!" Even my professor at my medical school told us this. So I ate badly all of December (birthday, holidays, etc!) and now I have what I'm realizing is psoriasis on my hands/fingernails. And a burning pain in my back/shoulders that I am assuming is arthritis? Also extreme muscle fatigue in my arms, I can hardly stir a pot of soup.. it's pretty ridiculous. Also not sure if this is related, but sugar makes me crash hard. As in I literally fall asleep. I'm back on fully gluten-free diet, but curious what your thoughts are about these results? When I called to ask the nurse she said it didn't mean anything. Thank you for reading!
I am in Pittsburgh and have been to multiple doctors for stomach issues. I had an endoscopy that showed "villous atrophy indicative of celiac sprue". I had IgG and IgA testing- both came back negative. I had genetic testing and the doctor says it is also negative, but the results say I am positive for: DQB1*03 DQB1*06 DQA1*01 DQA1*03 I have googled and googled with no luck. I guess I have a few questions. Can everything be negative and I still have Celiac disease? Or what else could cause the damage to my intestines? Does anyone know enough about genetics to interpret these positives? I know I shouldn't be seeking medical advice on a forum, but my doctors have been useless. Any advice is appreciated. Should I keep up the hunt for a doctor or is this a true negative? Thanks!