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Hi there, Thanks for taking the time to read this. I am so very confused, so thought I’d ask for help to see if anyone can understand my ANA results. I am currently under investigation for celiac and for ulcerative colitis. I had some bloods done last month and only through deciding to do a private referral (I am in the UK) have I found out there there are some abnormalities in my antinuclear antibodies. I asked my doctors for a print out of all my bloods. I have lower white blood cells, my ESR is very slightly raised. These are my ANA results: ENA ANTIBODIES - (SJM) • Ro antibody level - negative • La antibody level - negative • RNP antibody level - weak positive • Sm antibody level - negative • Jo-1 antibody level - negative • Scl 70 antibody level - negative DNA binding autoantibodies (SJM) - negative • Complement - third component - C3 - 1.39g/l (range 0.55-1.20) HEP2 ANA - (SJM) - Cytoplasmic Does anyone understand what this means? Do I ignore it? Why does it not say ANA negative or positive, but says cytoplasmic instead? Why is there no titre? I am no doctor so I have no idea, but I’d really like your opinion. Something has obviously been picked my from the lovely doctor I saw privately. I also have Raynauds Thanks so much for your help.
Hi everyone, I wanted to tell you all about an article that I came across as I was researching dsDNA and celiac correlation. When I had my testing done for celiac disease, my dsDNA was also detected which is a marker for SLE (Systemic Lupus Erythematosus) but my neurologist, family doctor and several other second opinions later, they all say I do not have lupus because of the low titer range being 1:10 and I never get the rashes nor joint pain association. I have had seizure type activity, photophobia, neuropathies, and weak muscles that I surely thought was lupus, however I never have had all of the criterion and things just didnt quite add up. I also tested positive for the deamidated gliadin peptide igG (DGP IgG) which indicates celiac disease. In doing research I found an article wriiten about a woman, Margaret Romero, who was diagnosed with lupus nephritis, and she found out that she had the genes for gluten intolerance. Her story is pretty remarkable and I wanted to ask you guys if you have heard of her before and what you think about her story. I will attach a link but I am not sure what the rules are for posting for links, but here it is, I hope that you can read it and see her success. http://celiaccorner.com/celiac-gluten-free-blog/surviving-a-dual-diagnosis-of-lupus-and-gluten-sensitivity/ I also found this study for those with lupus like symptoms and even diagnosis which turned out to be gluten sensitivity. http://ard.bmj.com/content/63/11/1501.full I am not saying this is EVERY case because everyone is different. I think for learning and knowledge purposes it can be very informative. It also may offer some of us relief. I wonder if celiac really can be mistaken for lupus? Has this ever happened to anyone here? Thanks in advance and I really hope that it is okay that I am giving these links for others to read.