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Hi, I've struggled with GI issues (IBS, GERD) and poly-cystic ovarian syndrome for the last 5-6 years (I am 26). My reflux has been continually getting worse and my doctor was concerned since I take high doses of Zantac. They referred me to specialty clinic for endoscopy. During my EGD doctor noticed lots of inflammation and he left a note stating that my villi in small intestine were flat. Only post op notes were to wait for the biopsy results of duodenum and along stomach; and to try another med. I've been having a lot of fatigue and easy bruising the last few months on top of worsening reflux. I've been primary surviving on chicken, bread, carrots...but it wasn't helping like it normally seemed to. Last week I started having joint pain that moves and comes/goes, as well as tingling in my hands and feet. After the tingling/joint pain started I stopped eating gluten/complex carbs because I thought maybe it was related to blood sugar; reflux is a little better but joint pain is not. Does this sound familiar to anyone? I had some blood work done for vitamins/minerals and liver function. Nurse over phone said it seems within normal limits; but that my liver function was on the lowest end of normal (AST =10). I have an appointment with my regular doctor tomorrow; as of Friday they didn't have my results but they wanted to follow up on joint pain/tingling.
Can Video Capsule Endoscopy Diagnose Celiac Disease When Esophogastroduodenoscopy (EGD) and Biopsy Fail?
Jefferson Adams posted an article in Celiac Disease & Gluten Intolerance ResearchCeliac.com 12/10/2012 - In celiac disease, doctors use video capsule endoscopy (VCE) mainly to follow-up on stubborn cases, and to diagnose adenocarcinoma, lymphoma or refractory celiac disease. However, some doctors are suggesting that VCE could replace standard esophagogastroduodenoscopy (EGD) and biopsy in certain circumstances. A team of researchers recently evaluated the use of VCE to diagnose celiac disease in place of esophagogastroduodenoscopy (EGD) and biopsy under certain circumstances. The research team included Matthew S. Chang, Moshe Rubin, Suzanne K Lewis, and Peter H. Green. They are variously affiliated with the Celiac Disease Center, Division of Digestive and Liver Diseases of the Department of Medicine at Columbia University College of Physicians and Surgeons in New York, and with the Division of Gastroenterology and Hepatology of the Department of Medicine at New York Hospital Queens, Weill Cornell Medical College in Flushing, New York. For their study, the team evaluated eight patients with suspected celiac disease who were diagnosed by VCE. Of the eight patients, four underwent EGD and biopsy, with negative biopsy results. Two patients declined the procedure, and two showed contradictory results due to hemophilia and von Willebrand disease. Using VCE, the team found that all patients showed mucosal scalloping, mucosal mosaicism and reduced folds in either the duodenum or jejunum. After treatment with a gluten-free diet, seven patients who participated in follow-up showed improvement in either their blood tests, or their presenting clinical symptoms. From this small study, the team concludes that VCE and the observation of the classic mucosal changes of villous atrophy may replace biopsy as the mode of diagnosis for celiac disease in patients who either decline EGD, or show contradictory results, or in suspect patients with negative duodenal biopsy. They encourage further study to determine the role and cost of using VCE to diagnose celiac disease. Source: BMC Gastroenterolohy. 2012;12(90)