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Showing results for tags 'gluteguard'.
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Celiac.com 10/12/2018 - Ever since I read the study about how caricain enzymes can break down specific gliadin peptides in celiacs on a gluten challenge, I've been hoping for a chance to try out Glutagen's GluteGuard enzymes. The tablets contain Caricain, which is an enzyme that is found in the skin of an unripe papaya fruit. According to the company, GluteGuard can help people manage their gluten-free diet better by supporting "gluten digestion" whenever they may encounter cross-contamination. Celiac.com's standard disclaimer about enzymes: If you have celiac disease AVOID ALL GLUTEN, and do not misuse these in a way that would cause you to knowingly eat gluten, or be less vigilant about your gluten-free diet. Glutagen advises that the supplement is not a treatment or cure for celiac disease, and it is essential that people with celiac disease maintain a strict gluten free diet. My GluteGuard Trial As soon as my sample bottle arrived I began taking them as per the directions on the bottle: One GluteGuard tablet before each meal, and I did this before every meal over a two week period. My goal was to see if I noticed any difference while taking them, in comparison to how I felt before. The first thing I noticed was that my digestion was suddenly kicked into overdrive, which means I had firmer stools, and shorter times in the bathroom. I was surprised to find my digestion improve so much, even when I knew that my diet was not in any way contaminated by gluten (at least as far as I know!), which was an added bonus. Eating Out I normally eat out 1-2 times per week, and I like to believe that I am very careful whenever I do this. However, a recent study has shown that 9 out 10 people are exposed to gluten when attempting to eat gluten-free in a restaurant. I would not call myself a "super sensitive celiac," but I did not notice any difference between eating out vs. eating at home, and more importantly, I had no issues after eating out five times during my trial period. Overall Impression I would recommend GluteGuard to anyone who wishes to improve their digestion, as it definitely improved mine, regardless of whether or not I was ever cross-contaminated during my trial of the product. For those on a gluten-free diet who do continue to eat out, or those who must do so when they travel, definitely consider this product as it may help prevent the very negative effects of cross-contamination. Visit their site for more information.
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Celiac.com 02/07/2017 - There's been a great deal of excitement, and plenty of confusion, among celiac sufferers about a drug that breaks down gluten into harmless smaller molecules. The good news is that the drug, GluteGuard, has shown some early promise in treating gluten intolerance in randomized human trials. The enzyme supplement currently available through Glutagen's website, and registered in Australia as a "listed complementary medicine". The bad news is that the drug is not designed as a cure for people with celiac disease, and even the company that makes the drug has concerns about exaggerated reports of how widely it can be used. The maker, Glutagen, claims that: "GluteGuard has been clinically evaluated in people with celiac disease who were challenged with 1gm of gluten per day for six weeks. GluteGuard was shown to significantly protect these patients from the serious symptoms they would normally experience after gluten ingestion. It is clear that GluteGuard prevents inadvertently ingested gluten from triggering the common symptoms of gluten sensitivity, whether individuals have coeliac disease, NCGS or other gluten allergies. GluteGuard was expressly designed for digesting the gluten peptides that induce symptoms and histological damage. Clinical studies proving it's utility were conducted in celiacs and dermatitis Herpetiformis individuals." The company is doing further studies, but as yet, at least as far as those who have celiac disease are concerned, there is only evidence that it may be a hedge against accidental gluten ingestion. GluteGuard is based on the papaya enzyme, caricain, which not only reduces gluten to smaller molecules, but further breaks down those products that negatively impact individuals affected by gluten. The company recently sought to clarify confusion among people with celiac disease by issuing a statement that reads in part: "The manufacturer of GluteGuard, Glutagen, advises the supplement is not a treatment or cure for coeliac disease and it is essential that people with coeliac disease maintain a strict gluten free diet." Bottom line is that if you have celiac disease, you must maintain a strict gluten-fee diet, and never willingly eat gluten, no matter what kind of supplements you take. Hoever, it you regularly travel or eat outside of your home it may be a good idea to use this supplement. Celiac.com will be among the first to announce any kind of cure or change to celiac disease treatment that might change that. Until then, stay tuned, and stay informed. Read an important notice regarding GluteGuard for people with celiac disease: Celiac.org.au This article was revised by Celiac.com on 11/02/2017 to address concerns that were raised by GluteGuard.
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Celiac.com 12/14/2017 - Can enzyme supplements help people with gluten sensitivity, including those with celiac disease? An Australian company is touting the results of a recent randomized, double blind study that supports enzyme supplements might be helpful for celiac patients in certain circumstances. The enzyme supplement was designed for people with celiac disease to use when facing likely or possible exposure to gluten, such as when traveling or eating food prepared outside their direct control. The company is careful to state that "enzyme supplementation won't cure celiac disease, and sufferers still need to avoid gluten." But the evidence from the two most recent studies does suggest that the product does help digest dietary gluten and could make life much easier for many people with celiac disease. The product, called GluteGuard, is based on a papaya fruit enzyme called caricain. This enzyme is shown to be helpful for celiac patients. A 2015 study showed adding caricain to bread dough reduced gluten toxicity to gluten by 90% for celiac patients. GluteGuard was recently evaluated in two clinical studies in Poland. The first study looked at 20 patients with celiac disease who were in clinical remission on a gluten-free diet. In that study, all patients ate one gram of gluten, equal to about one slice of bread, each day for 42 days, with 14 patients also taking GluteGuard and six taking a placebo tablet. Patients noted their symptoms and well-being each day, and received biopsies both before and after the study. Thirteen of the 14 celiac patients (93%) taking GluteGuard showed no adverse changes in clinical symptoms, biopsy results or well-being throughout the 42 day trial. Only one GluteGuard patient withdrew due to celiac-associated symptoms, while 4 of 6 taking placebo withdrew after 14 days due to adverse celiac symptoms. The second Polish study looked at the effectiveness of GluteGuard in patients with dermatitis herpetiformis, a gluten-triggered skin condition common in celiac patients. As with the first study, all patients in these study were in clinical remission. Patients consumed around six grams of gluten daily for seven days, with ten patients also receiving GluteGuard tablets and ten getting a placebo. The GluteGuard showed better results compared with the placebo group, with 81% showing no increase in areas of skin lesions and 71% showing a reduction in the appearance of skin lesions. The GluteGuard group also showed a 38% reduction in skin itchiness. Of the seven patients who withdrew from the study due to gluten symptoms, six were taking placebo. Both clinical trials met high scientific standards. In both studies, participants were randomly allocated to receive the treatment or placebo, and neither the participants nor the researchers knew owhich patient was receiving which intervention. So, yes, enzyme supplements may provide some help for people with celiac disease, especially as a hedge against minor or occasional gluten ingestion. So far though, they are not a magic bullet, and cannot replace a gluten-free diet. Read more at Medicalexpress.com.
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