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Found 6 results

  1. I've been gluten free for 2 months now. My doctor is still not sure whether I have non-celiac gluten sensitivity or celiac (blood tests positive, biopsies negative, still waiting for gene test results). Since going gluten free my hormones seem to have changed. My acne is suddenly back after being gone for years, my nails split and peel (something they did my whole life until I got pregnant, and then they were strong until now), my breasts are suddenly sprouting these odd tiny white hairs that pull out with no resistance, my PMS symptoms now include a delightful 4 or 5 days of loose bm's, and I get irritable and emotional around ovulation time. Has anyone else experienced something similar? I would've hoped any hormonal changes would've made me feel and look BETTER, not worse, but so far that doesn't appear to be the case. Is this typical while the body is healing?
  2. Celiac.com 05/16/2011 - Nearly 75% of the 24 million Americans suffering from autoimmune disease are women, according to the American Autoimmune Related Diseases Association (AARDA). Women appear to mount larger inflammatory responses than men when their immune systems are triggered, thereby increasing their risk of autoimmunity. The fact that sex hormones are involved is indicated by the fact that many autoimmune diseases fluctuate with hormonal changes such as those that occur during pregnancy, during the menstrual cycle, or when using oral contraceptives. A history of pregnancy also appears to increase the risk for autoimmune disease. The sex hormone that is commonly low in such women is Dehydroepiandrosterone (DHEA). This is a natural steroid and is produced by the adrenal glands, the reproductive organs and the brain. DHEA is used by the body to make the male and female hormones, testosterone and estrogen respectively, and is known to have anti-inflammatory effects. It has been proposed that a DHEA deficiency is a contributing factor in autoimmune diseases. Last year a study was done to look at precisely that effect. The study’s conclusions have been supported by other, similar research and I think you’ll find it quite interesting. The Journal of Clinical Endocrinology & Metabolism Vol. 94, No. 6 2044-2051(2009) published an article entitled “Low Serum Levels of Sex Steroids Are Associated with Disease Characteristics in Primary Sjogren’s Syndrome; Supplementation with Dehydroepiandrosterone Restores the Concentrations”. The authors investigated whether there was a relationship between steroid levels and the disease characteristics of Sjogren’s. They based their study on the known data that DHEA not only declines with aging but is reduced in Sjogren’s, an autoimmune disease. The study was populated by 23 post-menopausal women with primary Sjogren’s syndrome and subnormal levels of DHEA. The investigation was a controlled, double blind crossover study, conducted over a 9 month period, where DHEA was assessed by sophisticated laboratory measurements and typical symptoms of Sjogren’s such as dry mouth and eyes and salivary flow rates were similarly assessed. Results revealed a strong correlation between low DHEA and Sjogren’s symptoms. DHEA and its sex hormone metabolites (testosterone and estrogen) were found to increase with DHEA supplementation but not with the placebo. Symptoms such as dry eyes were seen to improve as estrogen levels The researchers concluded that the disease manifestations of primary Sjogren’s syndrome were associated with low sex hormone levels and the supplementation of DHEA allowed the body to transform into androgens, testosterone and estrogen, with testosterone production predominating. Please allow me to add some personal interpretation. For the most part I agree with the premise and applaud the results. The facts that autoimmune disease occurs more often in women, that women frequently have low DHEA, and that androgens have anti-inflammatory effects that can benefit autoimmune disease are all true. But should we simply give such women DHEA and call it a day? I don’t think so. I propose that we do three things: First, evaluate hormonal levels in women regularly; Second, address WHY their hormonal levels are imbalanced; And third, when supplementing with hormones such as DHEA, ensure that the delivery system is one that mimics what the body does naturally. Remember that autoimmune disease can begin many years before the first symptoms become manifest. Therefore evaluating hormonal levels in our younger women is a good idea. When I find DHEA levels that are low, my first order of business is to assess why. Frequently it is due to a phenomenon known as “pregnenelone steal” that occurs when the adrenal glands are under stress. It is a common occurrence and one of the fantastic abilities of the human body to shift from one pathway to another when under stress. The “steal” pathway diverts the body away from making sex hormones and instead it makes more “stress” hormones. So while adding some DHEA into the mix might very well help, does it make sense to find out WHY it’s being diverted away from making sex hormones? I hope so because it’s the very foundation of the medicine that we practice—functional medicine. Once you understand the root cause of the deficiency you can take steps to truly remedy it rather than simply covering it up by taking DHEA. Not to keep hitting you over the head with this concept, but supplementing with DHEA as your sole treatment misses the underlying cause since the body is designed to make adequate quantities of DHEA. A common reason for the diversion or “steal” pathway to become activated is adrenal stress from poor absorption of nutrients, unstable blood sugar and the presence of infections—all problems we see with the gluten intolerant patient! While I’m not implying that every autoimmune patient has a gluten intolerance, it certainly warrants screening all of them because of its high prevalence. As we travel down the road to optimal health through avoiding any food the body isn’t tolerating well, improving the integrity of the small intestine and normalizing adrenal function, there are certainly times when hormonal supplementation is beneficial. I don’t recommend the oral route because the first place the hormone travels is to the liver and this can be burdensome to that organ. When the body makes hormones naturally it delivers them straight to the bloodstream. In an effort to mimic that delivery system we use a buccal route (placed between cheek and gum in the mouth) that does a good job in bringing the hormone directly to the bloodstream and bypassing the liver and digestive tract. Autoimmune diseases comprise the third leading cause of death in our country and research strongly suggests that its rapid increase is due to environmental factors, especially those that weaken the small intestine. I am committed to earlier diagnosis while the disease is still remediable, as well as overall reduction of incidence through addressing digestive health. I hope you find this informative. Please share this information with those who have autoimmune disease themselves as well as in their family.
  3. Hi fellow celiacs! I have been diagnosed with celiac disease when I was 19 years old, 13 years ago! I have always face my diagnosis with optimism and a positive mind but as I grew older I started to feel a little hopeless sometimes about all my health issues that may or may not be related to celiac disease. I have always consider that I had a good health overall but now, at 32 I have a diagnosed celiac disease, I take mild medication for anxiety/depression, two years ago I started to have a hormonal imbalance and digestive disorders like ibs (maybe ¿?) and I often suffer from brain fog. I have always have high myopia, runner's knee, seasonal allergies... I am very careful with my gluten free diet but with the years If I accidentally get some gluten I get itchy blisters and one month ago I got something similar to eczema. It is my first time in a forum since I have started wondering if there is something else that I should be taking care of. I don't want to get to obsessed with my health but the truth is that I feel that I am young to have all this little health concerns. I am exploring alternative medicine solutions, specially related to nutrition to ease my different issues and heal my gut. I don't know any professional in my country that can take a holistic look at my health so I have done most of the research by myself in the internet which can be a little confusing and overwhelming at times... Any word of encouragement or advise will be much appreciated : ) All the best to you,
  4. Hi all, I had the best Dr's appointment yesterday, with my allergist, and he got me really thinking about what's going on with my body. After we talked about my allergies and how allergy shots were going (I'm so allergic 4+ to everything), I told him that I had been diagnosed with celiac disease in January and that I was still having trouble with bloating, D and fatigue. He says have you been tested for Hashimoto's? That it goes hand in hand so often with celiac. It turns out that his wife has both! This is the first Dr. I've encountered who has actual real life experience with this disease. So, I picked his brain for a while. We talked about how there are no good celiac Dr's where we live. He and his wife have been to see Fasano. He told me if I came up with any questions about celiac to feel free to call because he and his wife have been through it all over the past 2 years. Amazing appointment...a Dr who gets it!! Anyway, I was diagnosed with hypothyroid shortly after my oldest was born 14 years ago. I've never been tested for Hashimoto's. I've only ever had TSH and T4 tested. My allergist said that until the thyroid is working the way it needs to, the gut will have issues. Is that true? Could this be part of my issue? The last time I had my thyroid checked my TSH was 4.65. So, my Dr. upped my dose to 112 mcg. That was 4 weeks ago and I'm supposed to go in 2 weeks from now to have it re-checked. I think it's time that I ask for everything else related to the thyroid to be checked. Anyone know exactly what that is and what levels should be. Almost forgot...When I had my blood work done, both my ldl cholesterol and triglycerides were high...they've always been low before. I've been having so many weird issues lately....beyond the digestive, I've got some issues with my period and have realized thanks to my food diary that all of my digestive issues get much worse from ovulation-period. So 2 1/2 - 3 weeks out of the month I feel bad. Ugh. I guess I'm searching and wondering still, but things made sense yesterday. I guess it could also be female hormones...perimenopause? I will be 43 soon. I'm wondering if anyone knows how this all works together and how Hashi's and other hormonal issues could affect things like digestion, D, bloating and fatigue. Thanks in advance for all input and wisdom!
  5. This may be purely anecdotal, but I'm wondering if there's a connection between progesterone levels and DH flare ups. Back story: For as long as I can remember, I've had a very irregular period. I've averaged about 3 cycles per year, but it's improving since going gluten free about 5 months ago. Over the past several years, I've tracked my cycles as a way to prove to my doctors that it was really that serious. Because of this, even being irregular, I now know when I'm about to "start." I've also noticed that my DH tends to flare really bad in the two weeks leading up to my period. Those last two weeks are when progesterone levels increase sharply. (Look up a chart of hormone levels during a cycle and you'll see what I mean.) I know I saw a post on this forum about the progesterone-DH connection. It wasn't very detailed though and my searches have turned up very little. So does anyone have any info about this? Is it really that significant, or is it all in my head?
  6. I'm new here, and happy to be reading all the posts. I'm in the midst of a personal storm, both physical and emotional. I lost my son four months ago... and that should explain all my symptoms, especially the emotional. Except, my symptoms look more like celiac or gluten intolerance. I should mention that I am a Type 1 (insulin dependent) Diabetic. Briefly: 5 years ago I underwent a rapid weigh loss, and severe depression. I was given an endoscopy, blood tests for gluten... all were negative. Yet, the ONLY thing that helped me climb out of that mess and eventually regain my health and normal weight were eliminating gluten and dairy. (and eggs). At that time, a stool test through Genova/Metametrix did show off-the-chart sensitivity to gliadin. So, regardless of what the testing showed, I really stuck with the gluten-free diet. I've been fine since then, except if I cheat much on the gluten... I can "feel" the old symptoms coming back. But since I didn't have "celiac", I never was 1000% gluten free. Then in early January, I got a flu. I was already emotionally distraught over my son. And I do recall being more lax with avoiding gluten. (Went to several restaurants in Los Angeles on a trip, and wound up having a French Dip sandwich, some Chinese food with coated chicken, etc.) Suddenly the weight loss and fatigue are back... 20 pounds in two months. This time, huge abdominal issues, constant burping, constipation, nausea. Everyone is alarmed... and the depression is also oppressive. I just went back to a GI doc who did an MRI (looking for pancreatitis), and he also did the blood gluten testing, which was completely negative. I do NOT have fat in my stools, so this apparently rules out most major problems (including gluten intolerance?) The thing is, to prove that I am eating (and not simply depressed), I've kept a food journal. I'm eating 2500 calories or more every day, including a ton of fat and oil. WHERE does this food go, if not down the toilet, or digested onto my body? I should be big as a house. Any thoughts or advice would be SO appreciated! I haven't been able to work or function now in a month. Blessings~
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