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Showing results for tags 'mental health'.
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Celiac.com 12/27/2024 - Country music star Luke Combs, widely admired for his soulful voice and heartfelt lyrics, recently revealed a significant lifestyle change that has impacted both his mental and physical health. At 34 years old, Combs has taken steps to prioritize his well-being, a decision inspired by his desire to be a better father to his two young sons. A Surprising Change Luke Combs shocked fans with what he called "the least country thing" he's ever done: adopting a gluten-free lifestyle. The decision followed a period of heightened anxiety and obsessive-compulsive tendencies that began interfering with his daily life. These mental health challenges prompted Combs to delve deeper into understanding the root causes of his struggles. During his search for answers, Combs consulted a doctor in Nashville and underwent a food sensitivity test. The results revealed a significant gluten sensitivity, prompting him to eliminate the protein from his diet. Although Combs initially made this change to address his mental health, he was surprised by the broader impact it had on his overall well-being. Mental Health Transformation Since removing gluten from his diet, Combs reports experiencing profound mental clarity and reduced symptoms of anxiety and obsessive-compulsive behavior. "Ever since eliminating [gluten], it’s changed my life mentally," Combs shared. His story aligns with growing evidence suggesting that gluten sensitivity can exacerbate mental health issues in some individuals, though such outcomes may vary widely. This discovery was life-altering for Combs, as he had long struggled with mental health challenges that, at times, felt debilitating. Taking control of his diet proved to be a critical step in regaining balance and finding relief. A Positive Physical Side Effect Interestingly, Combs also noted a physical transformation as a result of his dietary shift, though weight loss was not his original intention. By focusing on his mental health and making sustainable changes, he inadvertently reaped benefits for his physical health as well. This unintended outcome has further motivated Combs to continue his wellness journey. Inspired by Fatherhood At the heart of Combs’ decision to prioritize his health are his two sons, 2-year-old Tex and 1-year-old Beau. Reflecting on his role as a father, Combs expressed his commitment to being present and healthy for his children. “Longevity is the goal,” he said. "Every day you get to spend with those guys is really fun and tough, and you need to be your best self to take care of them the way that you feel like they deserve." Balancing fatherhood and a demanding career is no small feat, but Combs is determined to rise to the challenge. For him, the effort to improve his mental and physical health is a deeply personal and ongoing process. Career Highlights and Dedication to Family In the midst of his personal transformation, Combs is also celebrating professional success. His latest album, Fathers & Sons, has earned multiple nominations at the 2024 Country Music Association Awards, including Album of the Year. Dedicated to his two boys, the album holds a special place in his heart, symbolizing both his love for them and his passion for music. “To be able to have something like that for them… and have it be recognized is always nice,” Combs said, expressing gratitude for the acknowledgment of his work. A Journey of Resilience Combs’ journey serves as a reminder that health is a multifaceted and deeply personal endeavor. His story highlights the importance of listening to one’s body, seeking professional guidance, and making lifestyle changes that align with personal goals and values. For Luke Combs, going gluten-free was not just about changing what he eats—it was about improving his mental resilience, building a stronger connection with his family, and laying a foundation for a healthier, more fulfilling life. His candid reflections on the challenges and rewards of this journey inspire others to take proactive steps toward their own well-being. As he balances fatherhood, career, and personal growth, Combs exemplifies how small but meaningful changes can have a transformative impact. For his fans and anyone facing similar struggles, his story is a testament to the power of perseverance, self-awareness, and love for family. Read more at: abcnews.go.com
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Celiac.com 12/13/2024 - The study investigates whether there is a causal relationship between autoimmune diseases and schizophrenia. Schizophrenia, a severe neuropsychiatric disorder, has been associated with immune system dysfunction in prior research. However, conflicting evidence has left the nature of this connection unclear. By using advanced genetic analysis, the researchers sought to determine whether autoimmune diseases and schizophrenia directly influence each other. Why Study Schizophrenia and Autoimmune Diseases? Schizophrenia is a complex disorder with genetic, environmental, and biological contributors. It affects approximately 1% of the global population and significantly reduces life expectancy. Autoimmune diseases, where the immune system mistakenly attacks the body, have also been linked to schizophrenia in observational studies. However, these links could be due to overlapping genetic or environmental factors rather than direct causation. Understanding these connections could pave the way for improved prevention and treatment strategies for both conditions. Study Design: Using Genetics to Uncover Causality This research used Mendelian randomization, a statistical method that analyzes genetic data to infer causality between factors. By examining genetic variations associated with both schizophrenia and 10 common autoimmune diseases, the study aimed to identify whether there are direct effects between the two. These diseases included conditions like celiac disease, lupus, type 1 diabetes, and psoriasis, among others. The bidirectional nature of the analysis meant that researchers looked at whether autoimmune diseases influenced schizophrenia and vice versa. A variety of statistical approaches were used to ensure robust results and account for confounding factors. Key Findings The study found distinct patterns in how schizophrenia and autoimmune diseases are linked: Autoimmune Diseases Increasing Schizophrenia Risk: Ankylosing Spondylitis: Genetic predisposition to this inflammatory arthritis was associated with a higher risk of developing schizophrenia. Autoimmune Diseases Decreasing Schizophrenia Risk: Celiac Disease, Type 1 Diabetes, and Lupus: Genetic markers for these conditions were linked to a lower risk of schizophrenia, challenging prior studies that suggested an increased risk. Schizophrenia Increasing Autoimmune Disease Risk: Schizophrenia was found to heighten the risk of certain autoimmune diseases, including inflammatory bowel disease (encompassing Crohn’s disease and ulcerative colitis) and psoriasis. No Causal Link Identified: Multiple sclerosis and rheumatoid arthritis showed no causal relationship with schizophrenia in either direction. Exploring Biological Mechanisms The study delved into why these links might exist. Several immune-related factors could explain the relationship: Immune Dysregulation: Schizophrenia and autoimmune diseases share immune system irregularities, such as imbalances in certain immune cells and altered cytokine levels. Genetic Overlap: Some genetic regions associated with schizophrenia also contribute to autoimmune diseases, suggesting shared pathways in their development. Inflammatory Triggers: Chronic inflammation and infections might simultaneously predispose individuals to both schizophrenia and autoimmune diseases. Antibodies and Neural Impact: In conditions like celiac disease, antibodies produced in response to gluten have been implicated in psychiatric symptoms, possibly linking immune responses to brain function. Study Strengths and Limitations This study was the first to use a large-scale genetic approach to comprehensively assess the relationship between schizophrenia and autoimmune diseases. By relying on genetic data, it avoided biases often present in observational studies. Sensitivity analyses further validated the results. However, the study had limitations: The genetic data came exclusively from individuals of European ancestry, so findings may not apply to other populations. It only included 10 autoimmune diseases, leaving the potential for overlooked associations with other conditions. Nonlinear relationships and environmental factors, such as stress or diet, were not accounted for. Implications for Those With Celiac Disease One of the most significant findings for individuals with celiac disease is the evidence suggesting a protective effect against schizophrenia. This aligns with earlier studies that found improvements in psychiatric symptoms for some schizophrenia patients who adopted a gluten-free diet. Although more research is needed, this connection underscores the potential importance of nutrition and immune health in managing mental health conditions. Why This Matters Understanding the links between autoimmune diseases and schizophrenia is crucial for advancing medical care. This research provides evidence of specific causal relationships, shedding light on potential shared biological mechanisms. For individuals with celiac disease, it offers reassurance that their condition may not increase—and could even reduce—their risk of schizophrenia. More broadly, the findings could inspire new treatment strategies that address the immune system to improve outcomes for those with schizophrenia. Read more at: bmcpsychiatry.biomedcentral.com Watch the video version of this article:
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Celiac.com 07/25/2024 - Patients with celiac disease must follow a strict gluten-free diet to manage their condition. However, this dietary restriction can introduce psychological challenges, including eating disorders and body image issues. This study aims to assess the prevalence of these psychological problems and their association with adherence to a gluten-free diet in individuals with celiac disease. Study Design and Population This cross-sectional study involved 217 patients with celiac disease aged between 18 and 55 years. Participants were randomly selected from the East-Azerbaijan celiac disease registry. The study excluded pregnant or lactating women and those with untreated comorbidities like diabetes and thyroid disorders. Participants were assessed using the 26-item Eating Attitude Test (EAT-26) for eating disorders, the Stunkard Figure Rating Scale (FRS) for body image issues, and the Celiac Dietary Adherence Test (CDAT) for adherence to a gluten-free diet. Prevalence of Eating Disorders and Body Image Issues The study found that 43.5% of participants had eating disorders, while 65.9% experienced body dissatisfaction, and 41.1% had body image distortion. These figures highlight a significant psychological burden among celiac disease patients, suggesting that managing celiac disease involves more than just dietary adherence. Association Between Gluten-Free Diet and Psychological Issues The analysis revealed a significant negative association between adherence to a gluten-free diet and the presence of eating disorders. Patients who strictly followed the diet were less likely to have eating disorders. However, the study did not find a significant relationship between diet adherence and body image dissatisfaction or distortion. This suggests that while a gluten-free diet may help reduce eating disorders, it does not necessarily improve body image issues in celiac disease patients. Psychological Barriers to Diet Adherence The study underscores the importance of considering psychological barriers when advising celiac disease patients on diet adherence. Patients with eating disorders might struggle more with maintaining a strict gluten-free diet, which can, in turn, exacerbate their psychological issues. This creates a cycle where psychological distress and dietary non-compliance feed into each other. Implications for Treatment Given the high prevalence of eating disorders and body image issues among celiac disease patients, healthcare providers should incorporate psychological support into their treatment plans. Nutritionists and dietitians should be aware of these potential barriers and work closely with patients to address their psychological needs. This could involve referrals to mental health professionals or incorporating strategies to improve body image and eating behaviors into dietary counseling. Conclusion This study highlights the significant psychological challenges faced by celiac disease patients, particularly concerning eating disorders and body image dissatisfaction. While adherence to a gluten-free diet can help mitigate eating disorders, it does not necessarily address body image issues. Therefore, a comprehensive approach that includes psychological support is crucial for effectively managing celiac disease. For patients, understanding these potential challenges can encourage them to seek holistic care that addresses both their physical and psychological needs, ultimately improving their quality of life. Read more at: biomedcentral.com
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Celiac.com 09/01/2023 - Celiac disease, a chronic autoimmune disorder triggered by the consumption of gluten, has long been associated with gastrointestinal symptoms and malabsorption issues. However, a growing body of research has shed light on an often-overlooked aspect of celiac disease: its potential impact on mental health. The intricate relationship between the gut and the brain, known as the gut-brain axis, is garnering attention for its role in influencing both physical and mental well-being. As scientists delve deeper into the complexities of this connection, a compelling picture emerges—one that suggests that the health of the gut could play a pivotal role in shaping our mental state. In this article, we embark on a journey through the fascinating landscape of celiac disease and its intricate relationship with mental health. We'll explore the mechanisms that underlie the gut-brain axis and how they contribute to various mental health conditions. We'll delve into the scientific evidence that links celiac disease to conditions such as anxiety, depression, ADHD, autism spectrum disorders, schizophrenia, and bipolar disorder. Additionally, we'll examine how nutritional deficiencies stemming from untreated celiac disease may exacerbate these mental health issues. As we navigate this intricate web of connections, we'll address the question of whether a gluten-free diet—one that is central to managing celiac disease—could also hold the key to alleviating mental health symptoms in gluten sensitive individuals. The Gut-Brain Axis: Exploring the Connection The intricate interplay between the gut and the brain is a captivating area of scientific inquiry that has been gaining momentum in recent years. This communication network, known as the gut-brain axis, serves as a two-way highway along which information travels between these seemingly distant organs. The gut, often referred to as the "second brain," is home to a complex ecosystem of trillions of microorganisms, collectively known as the gut microbiota. These microorganisms play a pivotal role in maintaining the gut's health and influencing various bodily processes, including those related to mental well-being. The gut-brain axis operates through intricate signaling pathways that involve both direct and indirect communication. The vagus nerve, a long cranial nerve that connects the brain to the abdomen, acts as a vital conduit for this communication. In addition, a dynamic network of biochemical messengers, including neurotransmitters, hormones, and immune molecules, enables the gut and brain to send and receive messages. The gut microbiota, which includes a diverse range of bacteria, viruses, fungi, and other microorganisms, has emerged as a key player in shaping this communication. These microbes contribute to the production of neurotransmitters such as serotonin, dopamine, and gamma-aminobutyric acid (GABA), which are not only crucial for brain function but also have a profound impact on mood regulation. A growing body of research suggests that imbalances in the gut microbiota, often referred to as dysbiosis, may contribute to mental health disorders. Understanding the gut-brain axis offers a fresh perspective on the way physical and emotional health intersect. Factors that disrupt the balance of this delicate axis, such as chronic inflammation, stress, and dietary choices, can have far-reaching consequences for mental health. As researchers unravel the intricate threads of this connection, they are uncovering insights that may pave the way for innovative therapeutic approaches to address mental health conditions, particularly in individuals with underlying conditions such as celiac disease. Celiac Disease and Mental Health: A Complex Link As we journey deeper into the realm of celiac disease and its implications for mental health, we encounter a multifaceted connection that underscores the complexity of human physiology. Celiac disease, an autoimmune disorder triggered by the ingestion of gluten—a protein found in wheat, barley, and rye—has long been recognized for its impact on the gastrointestinal system. However, the story does not end there. A growing body of research suggests that the effects of celiac disease extend beyond the gut, reaching into the realm of mental health. While the exact mechanisms that link celiac disease to mental health conditions are still being unraveled, several factors contribute to this intricate relationship. One of the key elements is inflammation. Untreated celiac disease triggers an immune response that leads to chronic inflammation within the small intestine. This inflammation has the potential to extend beyond the gut, affecting other systems within the body—including the brain. This raises the intriguing possibility that the inflammation associated with celiac disease could play a role in the development or exacerbation of mental health issues. Moreover, the gut-brain axis comes into play once again. The gut microbiota, a collection of microorganisms residing in the gastrointestinal tract, plays a significant role in influencing both physical and mental health. Emerging research suggests that the gut microbiota of individuals with celiac disease may differ from those without the condition. This dysbiosis could potentially impact the production of neurotransmitters, such as serotonin, that are crucial for mood regulation. The prevalence of mental health issues among individuals with celiac disease adds another layer of complexity to the equation. Studies have shown that individuals with celiac disease are at an increased risk of conditions such as anxiety, depression, and attention disorders. While the exact causal relationship between celiac disease and these conditions remains under investigation, the implications are undeniable. Understanding the connections between celiac disease and mental health not only sheds light on the broader impact of the disorder but also offers new avenues for therapeutic interventions. Anxiety and Celiac Disease: Breaking Down the Ties Research has revealed a compelling link between celiac disease and anxiety disorders. While the exact mechanisms remain a subject of ongoing investigation, several factors contribute to this connection. One notable element is the role of inflammation. Untreated celiac disease triggers an immune response that leads to chronic inflammation in the small intestine. This inflammation may extend beyond the gut, affecting other areas of the body, including the brain. Inflammation is increasingly recognized as a potential contributor to anxiety, as it can disrupt neurotransmitter balance and neural pathways. In addition to inflammation, nutritional deficiencies resulting from malabsorption in celiac disease could exacerbate anxiety symptoms. Nutrients like B vitamins, particularly B12 and folate, are essential for maintaining optimal neurological function. Deficiencies in these vitamins have been linked to mood disorders, including anxiety. The gut's compromised ability to absorb these nutrients can hinder their availability to the brain, potentially amplifying feelings of anxiety. As for the impact of a gluten-free diet on anxiety, findings are promising but complex. Some individuals with celiac disease report a reduction in anxiety symptoms after adopting a gluten-free diet. However, the relationship is not one-size-fits-all. It's important to note that anxiety can stem from various factors, and while dietary changes might alleviate symptoms in some cases, they may not be a standalone solution for everyone. Seeking professional guidance from both medical and mental health experts is crucial for individuals with celiac disease experiencing anxiety. Depression and Celiac Disease: Searching for Clues Among the spectrum of mental health conditions, depression stands as a particularly intricate puzzle. Its origins are multifaceted, influenced by a combination of genetic, environmental, and physiological factors. As researchers delve into the complexities of depression, a new avenue of exploration emerges—one that involves the interplay between celiac disease and this mood disorder. Depression, characterized by persistent feelings of sadness, hopelessness, and a lack of interest in activities, affects millions of individuals worldwide. Interestingly, studies have shown a higher prevalence of depression among individuals with celiac disease compared to the general population. The question that naturally arises is whether there is a genuine connection between these two seemingly unrelated conditions. One avenue of investigation lies in the realm of serotonin, a neurotransmitter known for its role in regulating mood and emotions. An estimated 90% of serotonin is produced in the gastrointestinal tract, where the gut microbiota plays a significant role in its synthesis. Here, the gut-brain axis comes into play once again. Untreated celiac disease, with its potential to disrupt the balance of the gut microbiota, could potentially impact serotonin production and utilization. This disruption may contribute to the development or exacerbation of depressive symptoms. Moreover, nutritional deficiencies associated with celiac disease could play a role in the development of depression. Nutrients such as B vitamins, folate, and iron are essential for optimal neurological function. Malabsorption in celiac disease could lead to deficiencies in these nutrients, potentially affecting mood regulation. For instance, vitamin B12 deficiency has been linked to symptoms of depression, fatigue, and cognitive impairment—symptoms that often overlap with those of celiac disease. Could a gluten-free diet offer a ray of hope for individuals with celiac disease who also grapple with depression? While the research is ongoing and the results are variable, some individuals report improvements in their mood after adopting a gluten-free diet. This phenomenon raises intriguing possibilities regarding the connection between dietary choices and mental well-being. However, it's important to note that depression is a complex condition with diverse causes, and a gluten-free diet may not be a standalone solution for everyone. Consultation with medical and mental health professionals is essential for those considering dietary changes to manage their depression. Celiac Disease, ADHD, and Cognitive Function: Insights and Considerations Attention Deficit Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder that affects both children and adults, characterized by symptoms of inattention, hyperactivity, and impulsivity. While traditionally associated with behavioral and cognitive challenges, emerging research suggests a potential link between celiac disease and ADHD. The relationship between celiac disease and ADHD is complex and multifaceted. While definitive causality has not been established, studies have highlighted intriguing associations between the two conditions. Individuals with celiac disease seem to be at a higher risk of developing ADHD-like symptoms compared to the general population. Additionally, some research suggests that individuals with ADHD might have an increased prevalence of celiac disease. One plausible connection lies in the potential impact of untreated celiac disease on cognitive function. Nutritional deficiencies, often a consequence of malabsorption in celiac disease, can affect various aspects of cognitive performance. Nutrients like iron, zinc, and certain B vitamins are essential for optimal brain function. Deficiencies in these nutrients might contribute to attention difficulties and cognitive impairments often observed in individuals with ADHD. Furthermore, the gut-brain axis plays a role in shaping cognitive function and behavior. The gut microbiota, with its influence on neurotransmitter production and immune responses, could potentially impact the neural pathways associated with ADHD. Dysbiosis or imbalances in the gut microbiota might disrupt these pathways, contributing to the development or exacerbation of ADHD symptoms. Could adopting a gluten-free diet offer potential benefits for individuals with celiac disease who also experience ADHD-like symptoms? While the research is still unfolding, anecdotal evidence and some studies suggest that dietary changes might have positive effects on cognitive function and attention in individuals with celiac disease and ADHD. However, the outcomes vary, and the efficacy of a gluten-free diet for managing ADHD requires further investigation. It's essential for individuals to work closely with healthcare professionals when considering dietary interventions for managing ADHD symptoms. Autism Spectrum Disorders and Celiac Disease: An Evolving Understanding Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition characterized by a range of challenges in social interaction, communication, and behavior. While the exact causes of ASD remain elusive, researchers have been exploring potential links between celiac disease and autism, shedding light on intriguing intersections between the two. The relationship between celiac disease and ASD is a topic that continues to evolve. Studies investigating this connection have yielded mixed findings, with some suggesting a potential association and others failing to establish a clear link. Despite the ambiguity, there are notable overlaps in genetic and immunological factors between the two conditions, prompting researchers to delve deeper into the shared mechanisms. One avenue of exploration lies in the immune system's role in both celiac disease and ASD. Both conditions involve immune dysregulation and inflammation, suggesting that disruptions in the immune response could contribute to the development of both disorders. Shared genetic markers and pathways further underscore the potential connections between celiac disease and ASD. Additionally, nutritional deficiencies resulting from untreated celiac disease may play a role in the development of ASD symptoms. Nutrients like zinc, iron, and certain B vitamins are crucial for optimal neurological development. Deficiencies in these nutrients, which are common in individuals with celiac disease, could potentially impact brain development and function, potentially contributing to ASD symptoms. The question of whether a gluten-free diet could positively impact individuals with celiac disease and ASD remains a topic of interest. Some parents and caregivers have reported improvements in certain behaviors and symptoms in individuals with ASD after adopting a gluten-free diet. However, the results are variable, and the research landscape is complex. Rigorous scientific studies are needed to establish the potential benefits of dietary interventions for individuals with both celiac disease and ASD. Navigating the relationship between celiac disease and ASD requires a comprehensive approach that takes into account genetic, immunological, and nutritional factors. As researchers continue to explore this connection, individuals with celiac disease and caregivers of those with ASD are encouraged to collaborate with healthcare professionals to make informed decisions that consider the individual's unique needs and circumstances. Schizophrenia and Celiac Disease: Investigating the Intersection Schizophrenia, a complex and often debilitating mental health disorder, challenges our understanding of the intricate workings of the brain. Characterized by symptoms such as hallucinations, delusions, disorganized thinking, and impaired cognitive function, schizophrenia remains an enigma in the field of psychiatry. Recent research has sparked interest in the potential connections between celiac disease and schizophrenia, shedding light on an intersection that warrants further exploration. The relationship between celiac disease and schizophrenia is a topic of ongoing investigation, and while the evidence is limited, it presents intriguing insights into the possible links between immune dysregulation, inflammation, and brain function. Some studies suggest that individuals with celiac disease may be at a higher risk of developing schizophrenia-like symptoms compared to the general population. Furthermore, a shared genetic susceptibility between the two conditions raises the possibility of overlapping mechanisms. One avenue of inquiry involves the potential role of inflammation in both celiac disease and schizophrenia. Chronic inflammation, a hallmark of untreated celiac disease, has been proposed as a contributor to the development of schizophrenia symptoms. Immune molecules released during inflammation could impact neural circuits and neurotransmitter balance, potentially leading to the characteristic symptoms of schizophrenia. Moreover, the gut-brain axis comes into focus once again. The gut microbiota, with its influence on immune responses and neurotransmitter production, could play a role in shaping brain function and behavior. Alterations in the gut microbiota composition, often observed in individuals with celiac disease, may influence immune responses and inflammation, potentially contributing to the development or exacerbation of schizophrenia symptoms. As for the potential impact of a gluten-free diet on schizophrenia symptoms, the landscape is complex and the research is limited. Some case studies and anecdotal reports suggest that individuals with schizophrenia and celiac disease experienced improvements in their mental health after adopting a gluten-free diet. However, these outcomes are far from uniform, and more rigorous research is needed to establish the potential benefits of dietary interventions for managing schizophrenia. Understanding the potential connections between celiac disease and schizophrenia offers a fresh perspective on the intricate interplay between the immune system, inflammation, and brain function. As the scientific community continues to delve into this complex relationship, individuals with celiac disease and those with schizophrenia are encouraged to engage in open dialogues with healthcare professionals to make informed decisions that consider their unique circumstances. Bipolar Disorder and Celiac Disease: A Complex Interaction Bipolar Disorder, characterized by extreme shifts in mood, energy, and activity levels, presents a unique challenge in the realm of mental health. Individuals with bipolar disorder experience periods of elevated mood (mania) and periods of depression, often accompanied by changes in behavior and cognition. While the origins of bipolar disorder are multifaceted, researchers are uncovering potential connections between celiac disease and bipolar symptoms, shedding light on an intricate interplay that warrants exploration. The relationship between celiac disease and bipolar disorder is multifaceted and not fully understood. Studies exploring this connection have yielded mixed results, making it difficult to establish definitive causality. However, shared genetic factors and the potential impact of inflammation on brain function suggest potential links between the two conditions. One avenue of investigation involves the role of omega-3 fatty acids, essential nutrients with anti-inflammatory properties. Individuals with celiac disease are at risk of nutritional deficiencies, including deficiencies in omega-3 fatty acids. These deficiencies could potentially contribute to neuroinflammation and impact brain function, potentially exacerbating bipolar symptoms. Furthermore, the gut-brain axis enters the spotlight once again. The gut microbiota's influence on inflammation, neurotransmitter production, and immune responses makes it a key player in the relationship between celiac disease and bipolar disorder. Imbalances in the gut microbiota, often associated with celiac disease, could potentially contribute to immune dysregulation and impact mood regulation. The potential impact of a gluten-free diet on bipolar disorder symptoms remains a topic of interest. Some individuals with bipolar disorder and celiac disease have reported improvements in mood stability and overall well-being after adopting a gluten-free diet. However, the results are variable, and the research landscape is complex. Rigorous scientific studies are needed to establish the potential benefits of dietary interventions for individuals with both conditions. As researchers continue to explore the complex connections between celiac disease and bipolar disorder, individuals with celiac disease and those managing bipolar disorder are encouraged to engage in conversations with healthcare professionals. Understanding the potential impact of dietary choices and addressing nutritional deficiencies could hold promise in the realm of mental health, offering a comprehensive approach to managing bipolar disorder symptoms. The Impact of a Gluten-Free Diet on Mental Health As the intricate relationship between celiac disease and mental health unfolds, the question that looms large is whether a gluten-free diet—an essential component of managing celiac disease—could potentially have a positive impact on mental well-being. While the research is complex and the outcomes are variable, investigating the potential effects of a gluten-free diet on mental health conditions sheds light on a promising avenue of exploration. Anxiety and Depression: A Glimmer of Hope? For individuals with celiac disease who also experience anxiety and depression, the prospect of a gluten-free diet alleviating their symptoms is an intriguing one. While studies investigating the direct impact of a gluten-free diet on anxiety and depression are limited, some individuals report improvements in their mood and overall emotional well-being after adopting such a diet. The reasons behind these improvements are not fully understood, but they could stem from a combination of factors, including reduced inflammation and improvements in nutrient absorption. Attention and Cognitive Function: Enhancing Clarity? In the realm of attention disorders and cognitive function, the potential benefits of a gluten-free diet for individuals with celiac disease and ADHD remain under exploration. Anecdotal evidence suggests that some individuals experience improvements in attention and focus after adopting a gluten-free diet. However, rigorous scientific studies are needed to establish the efficacy of dietary interventions on cognitive function in individuals with ADHD. Autism Spectrum Disorders: Navigating Complexity For individuals with celiac disease and autism spectrum disorders, the potential impact of a gluten-free diet on symptoms remains a topic of debate. Some parents and caregivers report observed improvements in behavior and communication after removing gluten from the diet. However, the results are highly variable, and research findings have been mixed. It's crucial for individuals considering dietary changes to collaborate closely with healthcare professionals to make informed decisions that consider the individual's unique needs. Schizophrenia and Bipolar Disorder: A Bridge to Explore In the realm of severe mental health conditions like schizophrenia and bipolar disorder, the evidence regarding the impact of a gluten-free diet on symptoms is limited. While some case studies and anecdotal reports suggest potential benefits, the landscape is complex and the outcomes are far from uniform. The relationship between celiac disease, inflammation, and these conditions raises intriguing possibilities, but further research is needed to establish the potential role of dietary interventions. In the pursuit of understanding the impact of a gluten-free diet on mental health conditions, it's essential to approach dietary changes with caution. While the potential benefits are promising, it's important to recognize that dietary interventions are not a substitute for professional medical and mental health care. Consulting with healthcare providers who specialize in both celiac disease and mental health is crucial before making any significant changes to one's diet. Conclusion The intricate relationship between celiac disease and mental health unveils a captivating narrative that underscores the interconnectedness of the body and mind. As we navigate the complex landscape of the gut-brain axis, immune responses, and nutritional influences, a mosaic of connections emerges—highlighting the potential impact of celiac disease on a spectrum of mental health conditions. The gut-brain axis, a bidirectional communication network, serves as a bridge between the physical and emotional realms. The gut microbiota, immune responses, and inflammation play pivotal roles in shaping mental well-being. While the mechanisms are complex and multifaceted, the emerging research paints a compelling picture—one that invites us to consider new perspectives on mental health. From anxiety and depression to ADHD, autism spectrum disorders, schizophrenia, and bipolar disorder, each mental health condition weaves a unique thread in the tapestry of celiac disease's influence. Shared genetic factors, immune dysregulation, and nutritional deficiencies intermingle to create a symphony of interactions that challenge our understanding of the mind's intricate workings. As individuals with celiac disease and mental health conditions seek answers, it's essential to approach the journey with patience, curiosity, and a commitment to holistic well-being. While a gluten-free diet holds promise for some, it's not a panacea. Collaborating closely with healthcare professionals—those who specialize in both celiac disease and mental health—offers a comprehensive approach to addressing the nuanced connections between these realms. The exploration doesn't end here. As science continues to advance, our understanding of the gut-brain connection will deepen, unveiling new insights and potential interventions. The complexities of celiac disease's impact on mental health remind us of the intricate tapestry that makes us human—a tapestry woven with the threads of genetics, environment, biology, and experience. In the journey toward unraveling the gut-brain connection, we bridge the gap between the physical and emotional, gaining a deeper appreciation for the profound interplay that shapes our lives. As we move forward, let us continue to foster open dialogue, advance scientific inquiry, and empower individuals to make informed choices that honor both their physical health and mental well-being.
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Celiac.com 07/06/2022 - More and more people are avoiding gluten and FODMAP food components (fermentable oligosaccharides, disaccharides, monosaccharides and polyols) over concerns about their potential connection to celiac-like reactions in the gut. In recent years, gluten-free diets (GFD) and low-FODMAP diets (LFD) have become more popular across the globe. This is due to intolerances or allergies in some people, but also due to the direct influence of marketing movements or diet trends on eating choices. At the same time, understanding, diagnosing and treating neurological and psychiatric diseases is becoming more important in numerous countries. A number of researchers have started to examine FODMAPs for that reason. Because of this, the research team conducted a bibliographic systematic review to see if there is a pathophysiological relationship between consumption of gluten or FODMAPs and mental disorders. The research team included Egoitz Aranburu; Silvia Matias; Edurne Simón; Idoia Larretxi; Olaia Martínez; María Ángeles Bustamante; María del Pilar Fernández-Gil; and Jonatan Miranda. They are variously affiliated with the Gluten Analysis Laboratory of the University of the Basque Country, Department of Nutrition and Food Science, University of the Basque Country in Vitoria, Spain; the GLUTEN3S Research Group, Department of Nutrition and Food Science, University of the Basque Country in Vitoria, Spain; the Bioaraba, Nutrición y Seguridad Alimentaria, in Vitoria, Spain; and the Centro Integral de Atención a Mayores San Prudencio in Vitoria-Gasteiz, Spain. The team's review gathered data from clinical and randomized controlled trials, based on the PRISMA statement, published since 2012. Their analysis found that limiting or ruling out gluten or FODMAPs may improve symptoms such as depression, anxiety, or cognition deficiency, and to a lesser extent for schizophrenia and the autism spectrum. Nevertheless, further studies are needed to obtain completely reliable conclusions. Read more in Nutrients 2021, 13(6), 1894.
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Celiac.com 06/27/2022 - Consumer gluten-free diet and sales of gluten-free products have increased immensely over the last decade, fueled in part by allergies and sensitivities in some, and by the popular perception that the diet is healthier by many others. The popularity of the gluten-free diet has led a group of researchers to explore the physical and mental effects that gluten might have on young people, especially in those with existing stomach and gut issues. The research team set out to assess the effects of gluten in adolescents and young adults with existing gastrointestinal symptoms and enrolled nearly 275 eligible adolescents, with at least four different gastrointestinal symptoms, from a population-based cohort of nearly thirteen-hundred. In phase one of the study, fifty-four participants lived gluten-free for 2 weeks. Thirty-three participants who improved during phase one then moved to phase two. Phase two was a blinded randomized cross-over trial, in which participants were blindly randomized either to start with 7 days of gluten, eating two granola bars containing 10g of gluten or to 7 days on placebo, eating two granola bars without gluten, followed by the reverse and separated by a 7-day washout period. The team measured any effects of the intervention on gastrointestinal symptoms and participant mental health. Overall, just under sixty of the 273 participants entered the run-in phase, with 35 eligible for randomization. A total of 33 were randomized, while 32 completed the trial. Average age was just over 20 years old, and nearly all participants were women. The team found that, compared with placebo, adding gluten to the diet did not trigger gastrointestinal symptoms or negatively affect mental health in adolescents who participated in this trial. Read more in Alimentary Pharmacology & Therapeutics 29 March 2022 The research team included Caecilie Crawley, Nadia Savino, Cecilie Halby, Stine Dydensborg Sander, Anne-Marie Nybo Andersen, Manimozhiyan Arumugam, Joseph Murray, Robin Christensen, and Steffen Husby. They are variously affiliated with the Hans Christian Andersen Children’s Hospital, Odense University Hospital, Odense, Denmark; the Department of Clinical Research, University of Southern Denmark, Odense, Denmark; the Section of Epidemiology, Department of Public Health, University of Copenhagen, Copenhagen, Denmark; the Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; the Department of Gastroenterology and Hepatology, Odense University Hospital, Odense, Denmark; the Division of Gastroenterology and Hepatology, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA; the Section for Biostatistics and Evidence-Based Research, the Parker Institute, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark; the Research Unit of Rheumatology, Department of Clinical Research, University of Southern Denmark, Odense University Hospital, Odense, Denmark.
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Hi, I have just joined the forum. I have had CFS for around twenty years now.I have also suffered with depression,anxiety,paranoia,brain fog/confusion,chronic stiffness in my joints,mood swings,difficulty concentrating,racing thoughts/mania,feverish chills,shallow breath.I found it hard to stretch my body and use my muscles correctly.I had to give up yoga classes after seven years because I lacked muscle memory and was 'bypassing' my joints to try and get into poses,causing more problems. I have tried all sorts of things,had many tests done.Although the doctors have tended to view things as mental health related,I have always felt there was a physical origin to the issue.The tests showed I have reactive hypoglycemia.I cut out sugar and high sugar fruits and found it easier to manage moods by recognising when I was going hypo,which would lead to irritation,anger,frustration.I learned how to combat depression. But I still had the fatigue,the feeling of heaviness,the tension in my muscles and joints,the anxiety,paranoia and mood swings.I felt so uncomfortable in my body.I still couldn't access muscles and use them properly,I felt like my brain was bursting out of my skull.My head and neck still felt like they were held in a vice.I had a lot of tension headaches.I had to constantly remind myself to breath.I felt crap in general. I have been seeing an osteopath regularly for four years now.This has helped me to regain some flexibility. I recently visited an herbalist,who believes I am gluten and dairy intolerant.I therefore went on a gluten and dairy free diet five and a half weeks ago.Since then I have noticed an improvement in my ability to access and use my muscles correctly.I am regaining flexibility.I am feeling power returning to my body.My head feels less swollen.I am regaining my senses,which felt like they were receiving sensory data from behind a barrier. I gather that gluten can cause inflammation in individuals who have gluten sensitivity,as the body's auto-immune response kicks in to fight the threat.And this inflammation can cause many different symptoms.For myself,I appear to have had inflammation in my brain,affecting my nervous system,breathing,co-ordination,mobility. Since changing my diet,I have had some strange pains in my head/face at times.I have felt more lethargic than usual.I have been feeling emotionally volatile.I had a manic episode.(This is not normal for me,I have generally been too tired to get manic and energised,though I have had bipolar tendencies).During this episode I felt marvellous,super confident,played guitar better than ever,hardly slept in three days. I would like to ask if there are others who have had similar symptoms of gluten intolerance and/or similar experiences during the adjustment to a gluten free diet? How long did it take to feel better? And has anybody had mental health diagnoses/issues which cleared up after going gluten-free? Thanks, Shamogi
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Supplementing with the eight essential B vitamins can help stop gluten cravings. Wheat products are required by law to be enriched with vitamins and minerals lost in processing. In other words, wheat products have vitamins added to them. Celiac Disease damages the small intestine where the B vitamins are normally absorbed. We often do not get enough B Complex vitamins while we are healing because of the damage done by Celiac and because the gluten free diet can be deficient in these vitamins. By supplementing with B Complex vitamins, the body will be ensured of getting all the B vitamins it needs to recover and function properly. I became very ill with vitamin and mineral deficiencies. The doctors I saw did not recognise vitamin deficiency symptoms. I'm a microbiologist, so I had studied this stuff at university. I knew the pharmaceuticals the doctors threw at me were not helping, the pharmaceuticals only covered up the symptoms, but the real problem remained. And I craved gluten, not for the gluten, but because they were a source of the vitamins my body was craving. I started supplementing with all eight essential B vitamins. Our bodies can't make them so they must be consumed every day, hence they are called "essential". Deficiency in many of the B vitamins will cause altered mentality. It's rare to have just a single vitamin deficiency. I've had Thiamine (Vitamin B1) deficiency that resulted in Wernicke's- Korsakoff syndrome and was written off as crazy by doctors and psychiatric "experts". High dose (more than 500 mg/day) thiamine therapy was the only thing that corrected that. Thiamine deficiency is associated with Anorexia, Bulimia, and Binge and Purge disorders, and Obsessive Compulsive Disorder. I've had Niacin deficiency that resulted in Pellagra and had mental changes with that. I've had Cobalamine deficiency (Vitamin B12) and experienced B12 deficiency dementia. Vitamin D deficiency caused severe depression. Magnesium deficiency caused horrible nightmares. Vitamin C deficiency caused skin problems and delirium. If we give our bodies the building blocks of essential nutrients, our bodies can heal themselves. I was ill because I was deficient in vitamins and minerals, not because I was deficient in pharmaceuticals. Doctors don't recognize vitamin deficiency symptoms. Doctors are trained in medical training institutions funded by big pharmaceutical companies to prescribe pharmaceuticals. I've posted previously in this thread studies done on mental health and vitamin deficiencies. Please read them. Vitamin and mineral deficiencies will affect your mental health. Correcting vitamin and mineral deficiencies will help more than putting a bandaid antidepressant on the problems. Correcting deficiencies promptly is important. Deficiencies left untreated can cause permanent brain damage which can be seen on MRIs. Here's some helpful reading... Nutritional therapies for mental disorders https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2248201/ And... Bread and Other Edible Agents of Mental Disease https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809873/#!po=18.0556 And... The Role of Vitamins and Minerals in Psychiatry https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046018/#!po=10.0000
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This is my first post here. I’ve looked at the website on and off for years, but could never get myself to join. I was diagnosed with Celiac disease when I was 6 years old. They noticed I was extremely malnourished and super thin, so they did some tests. Following that, they did a biopsy which confirmed what they suspected. My mother took to it right away. She was very strict about it. Same with my maternal grandparents, as they had my Grandmama (great grandma), who was diagnosed with celiac later on in her life. My paternal side, not so much. From my diagnosis to around 11 years old, they didn’t believe my diagnosis and therefore, did not follow my diet. I was sick constantly as a kid. Going further, it was hard to maintain the diet and the urges. The longest I’ve ever made it with no gluten was just over a year. It’s hard not to notice the connection between my binges and my depressive episodes. I’m now 18 and still struggle immensely with my relationship with food. I feel the symptoms and they get worse with every binge but I can’t seem to stop myself. I have been well aware of all the medical issues both life threatening and chronic, but it seemed to fuel my guilt and harmful thoughts. I am terrified now that all the issues I have currently were caused by my lack of self preservation. After years of balancing medications and going to therapy, I’m finally able to acknowledge the pain I’ve caused myself. I wish to speak to my family doctor about this but I’m also afraid of the judgement. Even worse than that, I am terrified she won’t believe me. So, how do I strictly follow my diet when the urge is stronger than protecting myself? How do I bring this up to my doctor? Christopher
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Celiac.com 03/21/2022 - Eating a gluten-free diet is the only current treatment for celiac disease, but managing that diet can be difficult. It can come with a substantial perceived treatment burden, and is tied to higher rates of psychopathology in adult patients. Some studies have identified psychological problems in children with celiac disease, but no systematic review has documented actual rates. However, it is still important to determine the risk for psychological comorbidities in children with celiac disease before they become adults. A team of researchers recently set out to review existing research on mental health issues in children with celiac disease, and to compile a psychosocial research and clinical agenda. The research team included Shayna Skelley Coburn, Elaine Leonard Puppa, and Samra Blanchard. They are variously affiliated with the Department of Gastroenterology, Children's National Health System; the George Washington University School of Medicine, Washington, DC; and the University of Maryland Medical Center, Baltimore, MD. The team researched a number of databases, including Scopus and PubMed, and followed up any relevant references to additional publication material. Two investigators screened studies for preset factors. They looked for electronically available peer-reviewed celiac studies, published in English, that included children. One investigator pulled the data, which the second investigator then reviewed. The team found twenty-six publications which met their criteria, including 16 case-control, 9 observational, and 1 clinical trial. Source materials differed in terms of symptoms examined, methodology, and population characteristics. A number of studies found that kids with celiac disease had an elevated risk for psychological comorbidities, along with poorer quality of life scores. However, a large number of studies were limited by small sample size, and inconsistent or non-validated methods of measuring psychological symptoms. Because numerous prior studies have shown increased rates of celiac disease coupled with psychological symptoms or diagnoses, the team stresses the need for screening for psychological issues in celiac patients, and also for celiac screening in psychological patients. Further study of the issue is also clearly warranted. By identifying the need for evidence-based recommendations for psychosocial research and practice in children with celiac disease, the team is setting the stage for better overall care and quality of life for people with celiac disease. Read more in Nutrients
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A Celiac's Quality of Life: Passages
Janet Blenner, Professor posted an article in Autumn 2009 Issue
Celiac.com 01/04/2020 - My interest in quality of life and celiac disease originated 4 years ago, beginning with my own diagnosis of celiac disease. I was relieved to finally have an accurate diagnosis after almost 15 years of misdiagnosis by an internist. He was convinced that my lack of energy was due to depression, but another physician, who suspected celiac disease, ran some tests and found that my lack of energy was due to limited absorption of nutrients. My psychological and subsequent physical relief over the diagnosis soon turned to frustration. I realized that I needed to adhere to a strict gluten-free diet. To my dismay, I found that many products contained gluten since it is an inexpensive binding agent. I also found it was necessary to be cautious about a variety of food products, vitamins, medications, toothpaste, lipstick and even postage stamps. I initially thought "Why wasn't I taught any of this in my nursing program?" There was a lot of information on diabetic diets but virtually nothing on the gluten-free diet. Of course, I also remembered that the teachers taught us that celiac disease only occurs in children. Being a nursing professor, I was also alarmed at how little my colleagues knew about celiac disease and the gluten free diet. After a lot of reading about celiac disease I realized how common it is for physicians to misdiagnose it. Adult celiac disease is not emphasized in medical, nursing or other allied health educational programs. I guess I should forgive my internist! I decided to educate every doctor, nurse, student, and anyone else who would listen. I am sure that people whispered "Here comes the celiac advocate again." Educating health professionals was interesting. In fact, one nurse said to me that she could never be on a gluten-free diet. I said to her "Like one has a choice". In addition, my life as a social butterfly was undergoing a metamorphosis. My pre-celiac diagnosis life consisted of social interaction with friends and associates at restaurants, parties and other social events. My husband and I also enjoyed eating out at good restaurants. In addition, I love world travel and sampling various ethnic foods. Passage: "Is this GF diet a conspiracy to ruin my life?" Compulsive grocery shopping I began to see life as having dealt me a nasty card. I do not enjoy grocery stores and I previously spent as little time as necessary shopping for food. I used the get in–get out approach. I rarely looked at food ingredients. Grocery shopping was just a means to an end. Now I must compulsively check ingredients for any hint of gluten. It has become the enemy and it is secretly hiding everywhere. And it's not just in the grocery stores. In some restaurants waiters told me that there was no gluten in the food, then arrived with a dish crusted in bread crumbs. I especially enjoyed the time when a waitress said that we do not use wheat in this dish and came out with a flour tortilla. I once interviewed a Chef who told me that she was on a gluten-free diet for one year. She said that it was the most frustrating experience of her life. She said that gluten forms the cohesive basis for most foods. It was what made baked goods nice light and fluffy. She was glad that she no longer had to be on the diet. Oh yes! Did I tell you that I have a shelf filled with many gluten-free cookbooks? They are busy collecting dust. Good intentions but not one has been opened yet. This is, in part, due to my workaholic schedule but the rest you can attribute to my lack of motivation. Health Food Stores and Gluten-free products Thank goodness for the celiac support groups. The group in my area has been so active and has encouraged the local health food stores to carry a lot more gluten-free products. To my surprise they sell GF fresh baked goods and other groceries. I was thrilled! However, I also started realizing that these products were often more expensive and some of the baked goods were very dense with calories compared to those that contain gluten. I was consuming a lot more calories than I should eat. Weight gain The next problem was gaining weight. Being able to absorb nutrients now, and the high caloric content of much of the GF products, caused me to gain weight. I decided to search for weight loss programs that could accommodate a gluten-free diet. Programs such as Jennie Craig do not accommodate GF diets. I finally found an expensive weight loss program that provided a nutrionist to develop a customized program. As with other things in my life, the program closed seven months later. Passage: Perceiving the glass is half -full Being on a Gluten-free diet has had some positive outcomes. Eating healthy and friends Shopping in health food stores has made me eat healthier than I have ever eaten in my life. My social life is diminished but I have some really good friends who consciously try to provide gluten free food for me. Others view it as though it is a preference on my part saying: "You can have a little gluten." I now know who my real friends are. Making new friends I was on a movie set a couple of months ago and a well known actor was there. I found out that he has celiac disease. It was like meeting an old friend. We talked for over an hour about gluten free diets, and the impact it has had on both our lives. You see, being a celiac helps you make new friends! A New focus for my life's work Being a celiac has also provided a new focus for my research. I am trying to help better understand the quality of life issues for those of us with celiac disease. I feel like I have this "inside" perspective. In conclusion Someone asked me the other day "If you had a week to have whatever you want, what would you choose?" I surprised myself by saying "To eat regular food for one week. That would be my dream." She laughed. Then she realized that I was serious. Maybe I haven't come as far in my passages as I thought.- 6 comments
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Celiac.com 02/15/2021 - A number of studies have tied celiac disease to psychiatric disorders, but there is still not much good data to support the connection. To get a better picture of the issue, a team of researchers recently set out to describe the epidemiology of several psychiatric disorders in celiac disease. The research team included Motasem Alkhayyat, Thabet Qapaja, Manik Aggarwal, Ashraf Almomani, Mohammad Abureesh, Omaymah Al‐otoom, Mohammad Zmaili, Emad Mansoor, and Mohannad Abou Saleh. They are variously affiliated with the Department of Gastroenterology, Hepatology, and Nutrition, Cleveland Clinic Foundation, Cleveland, Ohio; the Department of Internal Medicine, Cleveland Clinic Foundation, Cleveland, Ohio; the Department of Gastroenterology, University Hospitals Cleveland Medical Center, Cleveland, Ohio; the Department of Internal Medicine, University Hospitals Cleveland Medical Center, Cleveland, Ohio; University of Jordan Medical School, University of Jordan, Amman, Jordan; and Department of Internal Medicine, Staten Island University Hospital, New York City, New York. For their study, the team used a multi‐center database, called Explorys Inc, which offers electronic health record data from 26 major integrated healthcare systems consisting of 360 hospitals in the US. Of the 3,746,581 patients in the database between 2016‐2020, there were 112,340 patients with celiac disease. The team identified a group with celiac disease using the Systematized Nomenclature Of Medicine ‐ Clinical Terms (SNOMED–CT). They then conducted multivariate analysis using SPSS version 25. Compared to patients with no history of celiac disease, celiac patients were more likely to have a history of anxiety, depression, bipolar, ADHD, eating disorder, and autistic disorder. Patients with celiac disease and psychiatric conditions were more likely to be smokers, and to have a history of alcohol and substance abuse , along with a history of personality disorder. This large database study shows that celiac patients have a higher risk of having multiple psychiatric diseases including anxiety, depression, bipolar, ADHD, eating disorder, and autism. The team advises clinicians to keep mental health in mind when treating celiac patients, and to make psychiatric referrals as needed. Read more in Gastroenterology
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Celiac.com 08/25/2020 - A number of studies describe psychological disorders, in addition to other extra intestinal manifestations of celiac disease, such as fatigue, neurological conditions including headache and neuropathy. However, there hasn't been study with robust enough data to provide accurate risk estimates. In an effort to obtain accurate risk estimates, Jonas F. Ludvigsson, MD, PhD, of the department of medical epidemiology and biostatistics at Karolinska Institutet in Sweden, and colleagues analyzed data from the Swedish nationwide ESPRESSO cohort to explore associations between childhood celiac disease and psychiatric disorders. They matched nearly 20,000 children with biopsy verified celiac with up to five of 100,000 reference children, and gathered data on psychiatric disorders from the patient register. During a follow-up period of just over 12 years, nearly 17% of 3,174 children with celiac disease were diagnosed with a psychiatric disorder, compared with about 14% of the 13,286 control subjects. People with childhood celiac disease had a nearly 20% increase in risk for any psychiatric disorder, an increase seen in every childhood age group. Specifically, celiac patients faced elevated risks for mood disorders, anxiety disorders, eating disorders, attention deficit hyperactivity disorder, autism spectrum disorder, and increased use of psychiatric drugs. The risk was highest in the first year after celiac diagnosis, but continued into adulthood. The results of this study underline the importance of mental health monitoring in people diagnosed with celiac disease as children. Because of the elevated risk of psychiatric disorder, the team advises that people diagnosed with celiac disease in childhood receive both physical and mental monitoring into adulthood. Stay tuned for more on this and related stories. Read more at Healio.com.
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Celiac.com 01/09/2020 - Research indicates that having additional medical conditions is associated with a lower quality of life. One study looked at the combined influence of having a chronic disease and their perceived quality of life and wanted to see if it had an impact on suicide-related ideations or suicide attempts. Depression was clearly linked to both. The people who had a lower quality of life had more suicide-related ideation and suicidal attempts than those with a higher quality of life. With the strong association between people with celiac disease and depression, we need to have plenty of tools at hand to support this at-risk population. Intervention techniques, prevention methods, and treatment strategies should be considered for anyone with celiac, even if you do not currently have a diagnosis of depression. There Are Several Factors That May Feed Into Suicide Statistics Hypoperfusion - There is a strong gut-brain connection. People diagnosed with celiac already have villous atrophy in their gut. 73% of people with a sensitivity to wheat have hypoperfusion, a lack of blood flow to the brain. This can be caused by any food sensitivity. Low Levels of Neurotransmitters - Neurotransmitters like dopamine and serotonin are produced in the gut. A lack of both of these feel good chemicals is associated with depression and anxiety. In fact, 90% of your serotonin levels reside in the gut where it also serves the critical role of helping to stimulate contractions that push food through your intestines. Dysbiosis - Dysbiosis has been linked to major mood disorders. A gluten-free diet starves your body of some much needed nutrients. Nearly 80% of the prebiotics in our diets comes from wheat! These prebiotics are fuel for the probiotics that reside in your gut microbiome. When you take away the primary food supply (wheat) from your beneficial bacteria, you starve the probiotics. They die off unless you replace the prebiotics you’ve been getting from wheat, with other prebiotic foods. As good bacteria dies off, the bad bacteria continues to flourish and reproduce. This creates dysbiosis (an altered microbiome), an environment out of balance. Financial Concerns - Even your finances can have an impact on your mental well being. Several studies have shown finances impact the ability to adhere to a gluten-free diet. A study in Nova Scotia looked at 56 different gluten-free foods and compared them against their counterparts. Across the board, the gluten-free food was more expensive. Financial worries become an additional burden on a person already taxed with other serious concerns. A higher mortality rate is associated with the lack of adherence to a gluten-free diet. Studies show that people who are wealthier are able to comply with the dietary protocol more easily. The lack of adherence may stem from the depression, or it may be a contributing factor toward becoming depressed. Social Engagement Participation - Studies support a reciprocal relationship exists between an engaged lifestyle and cognitive function. People who are actively engaged in social activities, do better cognitively. Also, if you are functioning better cognitively, you are more likely to participate in mental, social, and physical activities. It revealed that they mutually influence each other. Isolation, depression, and high rates of suicide make it imperative that you don’t let a restrictive diet stand in the way of meeting the human need for socialization. Restrictive Diets Restrict Social Life (if you let them) You are faced with a lifetime of family celebrations, weddings, birthday parties, fraternity or sorority parties, festivals, and workplace events while living gluten-free. There is no, “I can’t wait until this is over” moment. Life on a gluten-free diet is from here on out. Food is such a focal point of celebrations for the majority of people, but it can be a source of disappointment and frustration for people with gluten-related disorders. Events can become less and less enjoyable when met with the same predictable frustration. You can’t have what everyone else is having - gluten-laden snacks, drinks, and entrees. You don’t know if that innocent looking side dish is gluten-free, and odds are the person that made it doesn’t either. Asking questions can wear you (and others) down, until you finally throw in the towel. Either you give up asking and eat it against your better judgement despite the impact it will have on your health, or you give up going out altogether in order to control your environment. Over time you may find others pulling away from inviting you to things, or you may pull away from social engagements. It can lead to isolation with Gloom and Doom as your new lifelong companions. Treatment and Intervention Unfortunately, people with celiac find the requirement of living gluten-free restricts their social life. This can lead to either abandonment of your gluten-free protocol (which is an absolute necessity for anyone living with celiac disease), or it can lead you to becoming isolated and lonely. Neither are good. You must adhere to a strict gluten-free diet. Like it or not, it is what your body needs. If you choose to dismiss your body’s need for that, you will see other chronic conditions pop up. They may be more serious and life threatening, or it may simply be more of a nuisance that you have to deal with. But your body will be sending out autoantibodies that attack your own cells, every time you eat even the littlest amount of gluten. Eventually, an autoimmune condition will be diagnosed that reveals what your body was up to. Let’s not do any further damage. Stick to the diet. Find a good therapist. This is especially important if you do not have a built in network of support. It is critical if you have depression. Venting to someone can really help take the weight off of the burdens you carry. Actively work to heal your gut, so it can better support you. You want to make sure that your microbiome is brimming with diversity. It should contain approximately 80% of what we would call good bacteria and 20% of what we might consider bad. Since that gut is sending messages to your brain directing it to how it feels and what it wants, be sure your brain is being steered by the good guys. Reach out for help. If you or a loved one are in crisis and feeling like you want to harm yourself, reach out for a lifeline and call the National Suicide Prevention Lifeline at 1-800-273-8255. You are not alone, and they are there to listen. Talk to them and find out how they can best support you during your darkest hours. Thanks to your ancestral design as a species, you function better with a support network to help you survive, and that is still true today. We all need others in our lives. Connect with others. Finding ways to reconnect with lost friends and family or connect with total strangers can be helpful in preventing feelings of loneliness and isolation, which can make depressive thoughts more present. Many celiacs suffer from isolation and exclusion. As their world becomes smaller, it makes suicide prevention even more challenging. So we need to find ways to keep people socially engaged and improve their quality of life. Practical Solutions for Maintaining Social Contact Plan to be spontaneous. I know that sounds like a contradiction, but when you want to continue living spontaneously, you need to be prepared for whatever life may throw at you. Carry a digestive enzyme with you at all times. Choose digestive enzymes that help to break down minor exposures to gluten within approximately an hour. This timing is critical because you want to make sure it is broken down before gluten proteins exit the stomach. That is when the autoimmune response gets triggered. This is not permission to eat foods with gluten, just protection against trace amounts of gluten that you may encounter in a restaurant setting or at a friends house - wherever life may take you. Adhere to that gluten-free diet. Higher mortality rates are associated with the lack of a gluten-free diet. Make sure that you address your gut health wholly, not just the absence of gluten, but the replacement of nutrients lost in the process - like prebiotics and probiotics. Improving your gut health will improve your overall health, including addressing issues surrounding depression and anxiety. Install a gluten-free restaurant locator app on your phone. Wherever you are, when you and your friends or family are ready to eat, find out which restaurants offer food friendly options. To be safe, take a digestive enzyme. One study provided a NIMA Sensor to 804 people. Out of the 5,600+ samples labeled gluten-free in restaurants, almost one-third came back as containing gluten. 27.2% of “gluten-free” breakfast items tested in the study came back as containing gluten. Dinner came in at 34%, with pizza and pasta coming in at skyrocketing numbers. Gluten-free pasta dishes in restaurants contained gluten 50.8% of the time, and gluten-free pizza served in restaurants contained detectable gluten 53.2% of the time. Carry a NIMA Sensor with you. A NIMA Sensor can detect trace amounts of gluten. If you order gluten-free food in a restaurant and it comes back “glutened,” know before you take that bite. Always carry some goodies with you, so you have something to eat. If you end up at a friend’s house, and it looks like almost everything they have is infected with gluten, rather than go home, eat a little something to carry you over or supplement it with the little bit that they do have that is gluten-free, like a piece of fruit. Find alternative opportunities to socialize in places that do not involve food. For instance, enroll in yoga, art classes, or a dance class. Don’t restrict yourself more than necessary. If chronic pain or sickness has you bedridden, talk to your friends and family on the phone. Facetime them or skype. Ask a friend over to watch a movie. Vary the friends a little, so you don’t restrict your world to one friend. Don’t be too embarrassed to ask friends to take you to appointments. You would do it for them if you could. Let them help you. Become the "hostess with the mostest." If you are one of those who loves a good party, show them how it is done with a 100% gluten-free buffet. Have those recipes ready to share with friends and neighbors, so that they can retrieve it for their future events when they are looking for a great recipe or a gluten-free recipe. Let people know that all of the recipes will be gluten-free beforehand, so that anyone with any concerns leaves them at home. Create and provide a list of gluten-free approved snacks for a weekly gathering like book club or game night. If others have food sensitivities, work this into the gluten-free list. It doesn’t matter if you end up with a list of only 5 things. This is just snacks and drinks that everyone can enjoy. This eliminates worries for everyone about what people can or can’t eat, and reduces the competitive urge to keep up with or outdo the person that brought food before them. Find ways to improve your quality of life. A lower quality of life is associated with a higher risk of suicide and a lower adherence to a gluten-free diet. Life may be very different from what you used to dream about, but that doesn’t mean you have to stop dreaming. Create a dream list and modify anything that is food-related to include or address those needs. You may find that most things that would improve your quality of life, have nothing to do with food. Dare to dream. Remember your now is not your future. Don’t cling to where you are now. Figure out where you want to be and how you can get there. Then live out loud.
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Celiac.com 08/05/2019 - The relationship between mental health, gluten sensitivity, and celiac disease has not been well researched. Some studies have shown that people with schizophrenia and bipolar disorder have elevated levels of antibodies to gliadin. A team of researchers recently set out to examine longitudinally the levels of antibody reactivity to gliadin in acute mania. The sample included 60 individuals assessed during a hospital stay for acute mania, 39 at a 6-month follow-up, and a sample of 143 non-psychiatric control subjects. The research team included Faith Dickerson, Cassie Stallings, Andrea Origoni, Crystal Vaughan, Sunil Khushalani, and Robert Yolken. They are variously affiliated with the Stanley Research Program at Sheppard Pratt, Baltimore, MD, USA, and the Stanley Neurovirology Laboratory, Department of Pediatrics, Johns Hopkins School of Medicine, Baltimore, MD, USA. The team used enzyme immunoassay to measure antibodies to gliadin. They used regression models to analyze the relationship between the antibodies and the clinical progress of patients with mania. Using multivariate analyses, the team found that patients with mania had significantly higher levels of IgG antibodies to gliadin at baseline, but not other markers of celiac disease, compared with control subjects. At the six month follow-up, however, these levels did not differ substantially from those of control subjects. In patients with mania, elevated levels after six months were strongly associated with re-hospitalization in the 6-month follow-up period. Based on these results, the team concludes that the monitoring and control of gluten sensitivity could be helpful in managing individuals hospitalized with acute mania. Stay tuned for more on this and related stories. Source: Psychiatry Research. Volume 196, Issue 1, 30 March 2012, Pages 68-71.
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Hello, I'm looking for a Gastro Psychiatrist or GI doctor who works with mental illness and would appreciate any recommendations. I've also thought about looking for immunologist who work with the gut microbiome. I live in Nebraska so a doctor in the Midwest would be ideal, but I would appreciate any recomendations! I struggle with anxiety, depression, and multiple food allergies. I've been gluten free about 6 months so I don't think I can be tested for celiac. I've been thinking about doing a gluten challenge to be tested, but out of all my food allergies gluten seems to make anxiety the worst. So, I'm not sure if its worth testing or just keep avoiding. While I've seen improvement in digestive and mental health symptoms since eliminating food allergies, I'm still struggling. I highly suspect I have immune related issues from dysbiosis as I was regularly put on antibiotics for sinus infections growing up. I have a lot of symptoms that point to Candida, histamine intolerance, or SIBO. It would be great to investigate some of these causes under the care of a physician. Any advice is appreciated! <3 Elizabeth
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About a 2 years ago, I was having trouble with shortness of breath. It went from shortness of breath to not being able to focus. I felt that there was saran wrap around my brain. Using google, I found that this was called dissociation-where the world can feel 2-dimensional, and you can even feel outside of yourself like an out of body experience. It feels like I am losing my mind! I was terrified of course and went to countless doctors. They continued to prescribe me anti-depressants. even though I insisted that I wasn't depressed, and there must be something else wrong. A cardiologist eventually found that I had POTS which is a blood flow problem essentially. There is no medication for POTS. Eventually, that feeling subsided slightly, until recently. Along with the "brain fog" (as my doctor calls it) and extreme shortness of breath, I was having diarrhea, dizziness, and all of the fun flu symptoms. I went to the ER and they thought it could be a reaction to my new birth control and ran tests for a blood clot. I had to do my own research and read that my symptoms aligned with Celiac disease. I was tested and sure enough, I am celiac. Now here is my problem. I have been following the gluten-free diet, as well as my vegan diet I have already been following with lots of fruits and vegetables. I am also not B12 or Vitamin D deficient as many with cognitive issues on celiac forums report to be. (In fact, my doctor said I have way too much B12 haha.) I am concerned that this feeling will never go away. It feels like 2 years since I have been myself, and I was really hoping celiac was the answer. I am still very sad about the diagnosis: my diet being very limited. (A Cuban without Cuban bread is blasphemy.) I just want gluten-free to feel worth it. I want to feel a change. Has anyone else dealt with ongoing problems within weeks of going gluten-free? My doctor made it seem that I would have immediate results, and that is just not the case with me. I can't take this disconnected feeling. I am graduating college in a week, and feel that I won't be able to be successful in this state. :/
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