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Found 2 results

  1. I am seeking more info from seronegative celiacs (celiacs where the blood tests did not show it) but later biopsy confirmed & from NCGS diagnosed whose symptoms were allieviated on the gfd What blood tests for celiac disease did you do? / Were your numbers totally low / normal? Were you gene typed? What were your results of gene typing? I'm especially curious to try to get a sense of if there are other DQ7 types out there who were seronegative.... but had symptoms resolve on the diet. Also were any of you ANA tested? (Asking because my kids are at risk. Half my husbands family are biopsy-confirmed celiacs - but most with weird paths to diagnosis - he was confirmed through DH skin biopsy / his sis never had a positive blood test but had tons of Marsh III lesions at time of endoscopy / first cousin had one equivical positive blood test as teen, when no damage was found on initial endoscopy doc advised her gluten was fine -- six years later new endoscopy showed major damage. Curious if there is a tie between genetic types. They haven't all been gene typed but we know my husband is DQ7)
  2. I've been experiencing some Celiac-like symptoms for a while now and could use some help making sense of these test results. Some history: I had a partial thyroidectomy 13 years ago (benign Follicular Adenoma). I take Synthroid 112 mcg daily. About 3 years ago, I starting experiencing hair loss, which my doctor attributed this to my throid and increased my synthroid. Then, I starting having numbness in my feet. My endo was concerned and ran what seemed like a million tests to discover that I was Vitamin B12 deficient. She told me to take OTC megadoses and then retested me to find I was still deficient. She prescribed B12 injections. The B12 seems to have stabilized, but still isn't ideal. Then, she tested my Vitamin D and found I was severally deficient there. OTC prescribed with no improvement. Prescription Vitamin D (50,000 Iu) every 7 days and then retested. I was still deficient and now my calcium was dangerously low, probably due to low D. Continued with the Vitamin D megadoses and then retested-both D and Calcium dangerously low and now my TSH is out of whack. The endo had me increase the D to 50,000 Iu every 5 days and add 600 mg of Calcium every night. She said she won't increase my Synthroid because she doesn't think I'm absorbing it and then referred me to a GI. I meet with the Gi who asks me about other symptoms. I report heartburn, flipping between consitpation and diarrhea, gas and bloating...He orders the blood test below and schedules an EGD. Immunoglobulin A, Qn, Serum 87 mg/dL (70-400) Deamidated Gliadin Abs, IgA 2 units (0-19) Negative 0 - 19 Weak Positive 20 - 30 Moderate to Strong Positive >30 Deamidated Gliadin Abs, IgG 3 units (0-19) Negative 0 - 19 Weak Positive 20 - 30 Moderate to Strong Positive >30 t-Transglutaminase (tTG) IgA <2 U/mL (0-3) Negative 0 - 3 Weak Positive 4 - 10 Positive >10 t-Transglutaminase (tTG) IgG <2 U/mL (0-5) Negative 0 - 5 Weak Positive 6 - 9 Positive >9 Endomysial IgA Negative After the EGD, the GI tells me that I have esophagitis and a gastric ulcer. They pulled tissue samples for a biopsy. He started me on a PPI to heal the ulcer. I heard from the nurse practitioner today, my biopsy results show lympohcytes indicative of early Celiac Disease but I have negative blood tests. I return to the doctor this Wednesday. Does anyone have any idea what this means?
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