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Showing results for tags 'percent'.
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South Med J. 2004;97:30-34 Celiac.com 03/30/2004 – According to Umaprasanna S. Karnam, MD (University of Miami School of Medicine in Florida), and colleagues, celiac disease is present in around 3% of iron-deficiency anemia cases. The researchers looked at all patients seen at the University of Miami for iron-deficiency anemia between 1998 and 2000. Iron-deficiency anemia was defined in their study as serum ferritin less than 25 ng/mL and hemoglobin less than 12 g/dL for women and less than 14 g/dL for men. Interestingly, patients with prior documented ulcerative or erosive conditions of the gastrointestinal tract or overt gastrointestinal bleeding during the prior three months were excluded (which means that many with advanced celiac disease would have been excluded from this study). Out of 139 possible patients with iron-deficiency anemia, 105 patients were included in the study (57 men and 48 women). According to the researchers: The prevalence of occult celiac disease in this prospective study of patients presenting with iron-deficiency anemia was 2.8%. A significant number of other gastrointestinal lesions amenable to therapy were also found on upper and lower endoscopy in these patients, the authors write. Given the treatable nature of celiac disease, it should be screened for in patients with unexplained iron-deficiency anemia with or without hemoccult-positive stools. The investigators recommend panendoscopy and screening for this treatable condition in unexplained cases. It is likely that had the study included patients with gastrointestinal bleeding or ulcerative conditions the rate of celiac disease would have been higher, perhaps as high as 5%.
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The Specific Carbohydrate Diet and the Two Percent Solution
Carol Frilegh posted an article in Additional Concerns
Celiac.com 05/03/2010 - Place a single tiny droplet of food coloring on a solid surface, a small plate will do nicely. Don't move it or touch it. What happens? Usually nothing. Do the same thing in a saucer of water and now what happens? The color spreads and permeates the water. This similar to the effects of eating a tiny amount of food restricted from your Celiac diet. I follow The Specific Carbohydrate Diet and it demands scrupulous attention to the kind of food I use and what is in it. The reason is that minuscule amounts of what we consider "The Undigestibles," feed bad gut bacteria, strengthen them, allow them to multiply and subdue friendly bacteria, all at the expense of a compromised digestive system. There are ways to determine food ingredients. We have all become more conscious of labels in recent years. Some tell us what is not in the product. I think for most of us celiacs, the magic words are "gluten-free." The Specific Carbohydrate Diet contingent is very fond of "free of starch, fillers, gluten and sugar." It's the favorite label of newcomers but not those in the know. That is because by US law, 2% of ingredients do NOT have to be disclosed on the label and are welcomed into our bodies by a gleeful band of bad bacteria creating a cause for celebration, feasting and procreation. Few commercial foods are approved for Specific Carbohydrate Diet and there are even problems with those that are. Ingredients and processing methods of store bought commercial foods are subject to change at any time and without notification. Periodically we contact companies requesting a document by regular mail or fax on company letterhead and signed by a living being. Email is not acceptable, neither is telephone validation. Does this sound reasonable? My own experience leads me to believe it is easier to have the Vatican approve a divorce than to squeeze a response even from certain juice companies whose products have been approved for years, something I attempted the last week in April 2010. Company number one agreed to send the letter. It hasn't arrived yet. Company number two looped me from Consumer Support to their nutritionist and I wound up in the legal department with assurance that they would get back to me (something like, "The check is in the mail?"). No word. These two products were chosen because of their wide availability in North America and even in a few other countries. What do I do? I have a very effective juicer! The fruit goes in with no additives and out comes juice with no additives, just as it should be. (we always dilute juice as in pure form it has too much natural sugar). It's my two percent solution.- 3 comments
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One Percent of Italian Schoolchildren have Celiac Disease
Scott Adams posted an article in Latest Research
Arch Dis Child 2004;89:499-501,512-515. Celiac.com 09/12/2004 – According to a recent study by Italian researchers, about 1% of Italian schoolchildren have celiac disease. The scientists screened blood samples taken from 3,188 schoolchildren aged 6 to 12 years for the presence of tissue Transglutaminase (tTG). The results showed that 33 tested positive for tTG, and of those 30 were verified by follow-up biopsies, and 3 refused biopsies but also tested positive for celiac disease-related antibodies and celiac disease-associated HLA DQ2-8. Out of the 33 who tested positive only 12 had symptoms. The researchers believe that the subsequent treatment of these children will likely help them to avoid future autoimmune disorders associated with untreated celiac disease. They also believe that because tTG screening is less expensive and more accurate than other forms of celiac disease screening, it should be used in the future for all mass-screening programs. They conclude that future mass screening programs deserve careful consideration.-
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BMJ 2004;328:322-323 (7 February) Celiac.com 02/18/2004 - A study conducted by researchers in the UK has found that 1% of all seven year old children in the UK have celiac disease, and most cases of celiac disease continue to remain undiagnosed. The researchers tested 5,470 "normal" children using a two stage screening that included an initial radioimmunoassay for antibodies to tissue transglutaminase (endomysial antigen), and a further testing of positive samples for IgA-EMA by indirect immunofluorescence. Children with tTG antibodies under the 97.5th percentile were defined as antibody negative. Out of those tested 54 were positive for IgA-EMA. Additionally: "IgA-EMA positive children were shorter and weighed less than those who tested negative for tTG antibody." The Researchers Comment: "At age 7, 1% of children were IgA-EMA positive and likely therefore to have sub clinical coeliac disease, though less than 0.1% were reported to be on a gluten-free diet. The prevalence of coeliac disease in these children is therefore comparable to that in UK adults. The benefit of early diagnosis of sub clinical coeliac disease remains unproven, but long term follow up of this cohort may help to resolve this. If screening is worth while, it should be started in childhood." "Since ALSPAC is an observational study based on analysis of anonymous samples, confirmatory biopsy was not possible...®eported clinical features were similar to those in adults with coeliac disease identified by screening. Gastrointestinal symptoms were not prominent, and the excess in girls mirrors that seen in affected adults. The most striking observation was that children with IgA-EMA were shorter by more than 0.76 standard deviation scores and lighter by 0.54 standard deviation scores than antibody negative children matched for date and place of birth. This equates to about 9 months growth and weight gain in an average child around this age. These features were independent of gastrointestinal symptoms and anemia and presumably unrelated to malabsorption." Conclusion: "Occult coeliac disease seems to start in childhood, even in those who are subsequently diagnosed as adults. The search for the trigger resulting in the breakdown of immune tolerance to gluten therefore needs to focus on infancy and intrauterine life."
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J Pediatr Gastroenterol Nutr 2001;33:462-465. Celiac.com 11/12/2001 - According to a recent report published in the October issue of the Journal of Pediatric Gastroenterology and Nutrition nearly 5% of US children with juvenile diabetes also have celiac disease. Dr. Steven L. Werlin of the Medical College of Wisconsin in Milwaukee and colleagues tested 218 patients with juvenile diabetes and 117 matched control subjects for the IgA endomysial antibody. Patients with positive results were offered a small bowel biopsy. The patients symptoms were assessed via a parent questionnaire. Results: Seventeen diabetic patients tested positive for the IgA endomysial antibody, while no positive results were found among control subjects. Fourteen of the 17 patients who tested positive underwent a follow-up small bowel biopsy. Villous atrophy was found in 11 of the patients. Two patients had increased intraepithelial lymphocytes without villous atrophy. Interestingly, more than half of the patients with biopsy-proven celiac disease were asymptomatic. According to Dr. Werlin, the results indicate that there is an association between asymptomatic celiac disease and juvenile diabetes. According to other research the treatment of the celiac disease in these patients will make the management of their diabetes easier. He further states that treating asymptomatic celiac disease will prevent many of its complications, and recommends that children with diabetes mellitus be screened for possible celiac disease with an antibody test and possible follow-up small bowel biopsy.
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