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Found 6 results

  1. Celiac.com 11/02/2017 - What is the link between the autoimmune diseases Sjögren's syndrome and celiac disease? In a study, 14.7% of Sjögren's syndrome patients were found to have celiac disease and 11.8% of non-celiac Sjögren's syndrome patients were found to have inflamed mucosa in the small intestine. With this knowledge, people who suffer from Sjögren's syndrome may be able to find relief for their symptoms with the gluten-free diet. Four million Americans are suffering from a disease they don't even know they have and their doctors don't even know to test for. Sound familiar? If you're familiar with my work as a gluten-free advocate, you have probably guessed that what I'm describing is celiac disease, an autoimmune reaction triggered by gluten, a protein component in wheat, barley, and rye. If that was your guess, you would actually be wrong: there is another underdiagnosed and common autoimmune disease that we and our doctors need to be aware of—Sjögren's syndrome, which affects the exocrine, or moisture-producing, glands. Unlike celiac disease, Sjögren's syndrome doesn't have a standardized effective treatment, but fortunately, research is demonstrating a link between these two autoimmune diseases, bringing good news for Sjögren's patients who may see relief of their symptoms by eliminating gluten from their diet. Chances are, many haven't heard of Sjögren's syndrome. This relatively unknown and underdiagnosed disease is an autoimmune disease in which the immune system attacks the tear and saliva glands of the body, reducing their production and resulting in dry mouth and eyes and other symptoms. Complications of Sjögren's include tooth decay, corneal ulcers, and non-Hodgkin's lymphoma. In women, vaginal dryness can also be a symptom. According to the UK's National Health Service, 9 out of 10 people who suffer from this condition are women, and the average age onset is between the ages of 40 and 60 years old. In a study by the Institute of Medical Technology, University of Tampere, Finland, 34 Sjögren's syndrome patients and a control group of 28 people were given a small bowel biopsy; five (14.7%) of the Sjögren's patients tested positive for celiac disease and four (11.8%) of the non-celiac patients were found to have inflammation in the mucous membrane of the small intestine. According to the study's conclusions, "The findings show a close association between Sjögren's syndrome and celiac disease." Currently, there are two classifications of Sjögren's syndrome as either primary, meaning that it has developed on its own, or secondary, which means that it has developed as the result of another autoimmune disease, such as rheumatoid arthritis or lupus. There is no "cure" for Sjögren's; researchers have identified a combination of factors—environmental, genetic, and hormonal, according to the National Health Service. There are a variety of treatments which can vary in effectiveness, including saliva-stimulating medication and eye drops. The good news is that Sjögren's patients who are found to be celiac may see the relief of their symptoms through a gluten-free diet, currently the effective and only treatment used for celiac disease. Just as with celiac disease, Sjögren's syndrome is under diagnosed relative to its frequency. As a diagnosed celiac American, I consider myself very lucky that I've been correctly diagnosed with celiac disease. With the help of advocate groups all over the country, gluten-free awareness and celiac diagnosis is on the rise. By spreading the word about the association between Sjögren's syndrome and celiac disease, we can help those with Sjögren's achieve better health and quality of life. Resources: National Health Service (UK): Sjögren's syndrome http://www.nhs.uk/conditions/Sjogrens-syndrome/Pages/Introduction.aspx National Institutes of Health: Celiac disease and markers of celiac disease latency in patients with primary Sjögren's syndrome http://www.ncbi.nlm.nih.gov/pubmed/10201480 Nutritional Healing: Articles. Sjögren's World: Links http://www.sjogrensworld.org/links.htm
  2. So what's the verdict on false negatives? Because I had my biopsy four years ago and it was negative, my IGA was ignored because it was always 10-20 points below the normal range- but my stomach has never completely recovered from the hellish 8 week pre-biopsy gluten trial I did in 2012 and I have been progressively more sick each year in new and exciting ways. Now I've been diagnosed with Sjogren's at 24. I plan to go back to actually watching for gluten cc instead of just eating whatever claims gluten-free status without certification either way but I admit I still wonder about Celiac each time a new digestive or autoimmune symptom pops up.
  3. Hi all, I'm having a bad week.. I was recently just diagnosed with yet another autoimmune - Sjogren's syndrome . I'm reaching out to see if anyone else on this forum also has Sjogren's and can share their experiences. My PCP diagnosed it with a blood test (negative SSA antibodies, positive SSB, negative ANA) and referred me to a rheumatologist. Unfortunately, I have to wait a couple of months to see the rheumatologist, but I'm getting so anxious wondering what to expect. I've read a lot of different information on the internet when researching it (I really need to stop with Googling it as it really puts me in a panic). Do they put you on immunosuppressives or DMAR drugs, or does it depend on the severity? Can it be managed with OTC meds? I'd prefer not to go on any immunosuppresive type meds. All of my other bloodwork came back normal (CBC, CMP, sed rate, CRP and other Lupus tests). Thanks to anyone for their help/support
  4. Hello all, I just found this forum and I would like to introduce myself. I have recently been to the allergist due to a host of food allergies. Like, this is really not cool, I'm running out of stuff to eat! Over the course of 10 years or so, I've been to the allergist 3 times for skin testing. I've got horrible environmental spring, fall, summer, and even winter 'allergies'. Nothing has come up save for this last time: cat and dog. I can't eat beef, I break out in hives, get miserably itchy, and oh yeah, the wheezing. Yet, I'm not "officially" allergic. Dairy gives me horrendous gastrointestinal issues. Most recently, I damn near had to go to the ER again after a reaction to almonds. The list goes on. My Dx the last time around for the allergies was nonallergic rhinitis. That didn't tell me anything else, really. Since nothing really showed on this round of testing, and a lot of my reactionary symptoms center around the itching, the doc ran a liver panel. I've seen the preliminary results and my AST, ALT, and GGT are elevated. Not astronomically, but outside of the "normal" range. At this point, I'll mention that I've got an aunt with Sjögren's, and an aunt with celiac disease. I've had asthma since I was a teen, and digestive issues in the way of constipation for as long as I can remember. After a little bit of google-fu on this liver function thing, Celiac Disease cannot be ruled out at this point. I looked at the rather extensive list on the U of Chicago website for celiac symptoms, and I'll be damned if just about every single thing that's ever been wrong with me isn't on that list! I feel like I'm going crazy with this right now, as celiac disease and/or Sjögren's are my primary suspicions. My mom's sisters are the aforementioned aunts so of course, my mom thinks I'm crazy for thinking celiac disease, but I really, really don't think it's even a stretch. I think it's a very viable possibility at this point. I've naturally gravitated away from breads, pastas, etc because I'm trying to lose that last 10 or so. I haven't gone gluten-free, but hadn't really put two and two together with the malaise, fatigue, nausea until the past few days. I'll be damned, I feel like THIS COULD REALLY BE IT!!! Brain fog, bloating, headache, after eating gluten - crackers, wheat in my tofu product, bread. Oh, the stomachache too. Keep in mind, while I'm glad that my aunt has many more food options nowadays, I've been wary of the gluten-free fad thing. For people that don't actually NEED to go gluten-free, it's unnecessary and ridiculous. Now that I'm looking at this possibility, there's a chance that I may be eating some crow with gluten free fixings. Ha. While I wait to discuss this further with the doc, I'll be here, probably asking questions as I go. I'm not completely crazy for making this leap, am I?
  5. Having multiple food sensitivities can be frustrating (and downright painful), but finally identifying one that has been creating havoc in your life is like winning back some of your life. My biggest battle won was discovering the link between my bi-weekly migraines (not good when you are trying to work as a surgeon) and corn-starch (which, as most here know, is in almost everything, including most gluten-free foods). In my case, it was also in the powered gloves and toothpaste I used, plus the medication I took for the migraines! Corn starch also triggered Sjogren's Syndrome (an immune-mediated situation in which I have no tear production, no nasal mucus and no saliva production - painful!!) Anyone with chronic dry eye, dry mouth or dry nostrils should research this. Sjogrens, for me, is a mixed blessing/curse. Because it starts very, very quickly when I ingest or get exposed to an intolerable ingredient, I have learned that I can't tolerate some pretty weird things that I wouldn't have suspected would cause trouble. Short and sweet, the following triggers my migraines and/or Sjogren's Syndrome: corn starch, wheat/barley gluten, apples*, shrimp, cauliflower*, grapes*, plus exposure to artificial fragrances, cedar or pine chips, cat litter, molds & mildews, dog fennel and dust mites. (*even home-grown organic) Problematic, but dose-dependent: rice, raisins, cats. A godsend for me, to deal with fibromyalgia and neck/torso pain secondary to a very bad horseback-riding accident, is dry-needling done by my physical therapist. That and deep muscle work have given me a huge chunk of my life back. For those of you with similar corn-starch sensitivities, BC Powders (aspirin and caffeine) contain no corn starch, and they work well. My best to all.
  6. Collin P et al. (1994) Celiac disease - associated disorders and survival. Gut vol 35 (9):1215 1218. Abstract: The associated diseases in 335 celiac patients diagnosed 1980-1990 were compared with age and sex matched control patients with various gastrointestinal symptoms. Endocrine disorders were found in 11.9% of celiac and 4.3% of control patients (p=0.0003). Celiac patients had insulin dependent diabetes mellitus significantly (p=0.0094) more often (5.4%) than control patients (1.5%). Connective tissue diseases were found in 7.2% of celiac and 2.7% of control patients (p=0.011). Sjogrens syndrome occurred in 3.3% of celiac patients and 0.3% of controls (p = 0.0059). Autoimmune thyroid diseases were found in 5.4% and asthma in 3.6% of celiac patients but also in 2.7% and 3.6%, respectively, among control patients. The incidences of malignant disease and the survival rate in celiac patients were compared with those in the Finnish population. Ten celiac patients developed a cancer during the follow up (mean 5.3 years, range 1-12) but none had a lymphoma. The risk of malignant disease did not differ from that in the Finnish population in general. Eleven celiac patients died during the follow up. The five year survival rate of celiac patients did not differ from those in the general population. At least 83% of the celiac patients adhered strictly to the gluten free diet, which may explain the favorable outcome.
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