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Jefferson Adams posted an article in Celiac Disease & Gluten Intolerance ResearchCeliac.com 07/17/2018 - What can fat soluble vitamin levels in newly diagnosed children tell us about celiac disease? A team of researchers recently assessed fat soluble vitamin levels in children diagnosed with newly celiac disease to determine whether vitamin levels needed to be assessed routinely in these patients during diagnosis. The researchers evaluated the symptoms of celiac patients in a newly diagnosed pediatric group and evaluated their fat soluble vitamin levels and intestinal biopsies, and then compared their vitamin levels with those of a healthy control group. The research team included Yavuz Tokgöz, Semiha Terlemez and Aslıhan Karul. They are variously affiliated with the Department of Pediatric Gastroenterology, Hepatology and Nutrition, the Department of Pediatrics, and the Department of Biochemistry at Adnan Menderes University Medical Faculty in Aydın, Turkey. The team evaluated 27 female, 25 male celiac patients, and an evenly divided group of 50 healthy control subjects. Patients averaged 9 years, and weighed 16.2 kg. The most common symptom in celiac patients was growth retardation, which was seen in 61.5%, with abdominal pain next at 51.9%, and diarrhea, seen in 11.5%. Histological examination showed nearly half of the patients at grade Marsh 3B. Vitamin A and vitamin D levels for celiac patients were significantly lower than the control group. Vitamin A and vitamin D deficiencies were significantly more common compared to healthy subjects. Nearly all of the celiac patients showed vitamin D insufficiency, while nearly 62% showed vitamin D deficiency. Nearly 33% of celiac patients showed vitamin A deficiency. The team saw no deficiencies in vitamin E or vitamin K1 among celiac patients. In the healthy control group, vitamin D deficiency was seen in 2 (4%) patients, vitamin D insufficiency was determined in 9 (18%) patients. The team found normal levels of all other vitamins in the healthy group. Children with newly diagnosed celiac disease showed significantly reduced levels of vitamin D and A. The team recommends screening of vitamin A and D levels during diagnosis of these patients. Source: BMC Pediatrics
PCB posted a topic in Celiac Disease - Post Diagnosis, Recovery/Treatment(s)I am 80+, have a brother with celiac and was well until an acute autoimmune illness at Xmas 2009 possibly following flu. After extensive rather inconclusive hospital tests this seemed to be resolving on multivitamins and minerals only, apart from persistent anaemia. Tests for celiac were carried out at my request at the end of 2012: antibodies +, biopsy + (Marsh 2). Strict gluten-free diet from Jan 1st 2013. From 2010 to present I have had 15 episodes of temporary loss of central night vision usually lasting a few days and looking like a dark C or its lower part, about 20º wide and different in the two eyes. I thought it must be due to vitamin A deficiency but it did not respond quickly to extra vitamin A and one blood test showed a normal level. On April 26th 2013 after a fish buffet night vision recovered completely but failed again slightly next day. In the latest episode lasting 9 days it improved after eggs on 2 successive days and resolved completely after one 1000mg cod liver oil capsule. This suggests that it might be due to malabsorption of omega 3 fatty acids, possibly DHA. Has anybody else out there had similar symptoms and are they indeed a useful indication of persistent malabsorption despite the gluten-free diet?