Jump to content
  • entries
    23
  • comments
    37
  • views
    18,633

About this blog

 

 

😸

Entries in this blog

Thiamine and Autoimmune Diseases

Thiamine Deficiency, Hypoxia, and Autoimmune Disease

Thiamine deficiency causes hypoxia.  Hypoxia-Inducible Factor 1α binds to thiamine transporter SLC19A3 and activates it to increase thiamine uptake.  HIF-1α signaling also triggers the release of inflammatory cytokines and inflammatory cells proliferation.  HIF-1a affects genes in the nucleus, entering through micro-pores.  Hypoxia and high levels of HIF-1a are found in many autoimmune diseases and cancer. "HIF-1α shows its functions through translocating into the nucleus, dimerizing with H
knitty kitty
0
Thiamine and Autoimmune Diseases

Thiamine and Autoimmune Diseases

Thiamine and Autoimmune Diseases Human Leukocyte Antigens are coded for in our DNA.  They act like street signs on cells so the body knows that they are "Self".   Tissue typing in organ transplantation looks for donors with "Self" street signs similar to the recipient's in order to prevent rejection of the transplanted organ.   The HLA DQ genes code for immune cells.  Some immune cells are encoded to recognize certain protein strings when that protein string attaches to the receptor on
knitty kitty
2
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.