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Digestive enzymes won't help with gluten disorders per se but can often help with pancreatic enzyme deficiency related digestive problems. I'm not sure that having an IGA deficiency necessarily predisposes one to decreases in infection fighting ability but that's a good question to ask your physician. 

Thank you for sharing your journey—it sounds like you've been through a lot, and you're being incredibly proactive about your health! Celiac disease and gluten intolerance can be tricky to navigate, especially when there’s conflicting advice from different doctors. It’s great that you’re feeling healthier on a gluten-free diet, but I understand the frustration of wanting a definitive diagnosis. To answer your question about reintroducing gluten for the test, it’s important to follow your doctor's advice carefully. The "gluten challenge" (which is what you’d be doing to trigger an accurate test) typically involves consuming gluten daily for about 6 to 8 weeks. Most guidelines recommend eating 1-3 slices of bread per day (about 3 grams of gluten daily) to ensure enough gluten exposure for the test to detect damage or antibodies. Given your small size, you might want to start slowly with 1 slice of bread or the equivalent (like a small bowl of pasta), but consult your doctor or gastroenterologist for specific recommendations. It's crucial that you maintain the gluten intake during the period, even though you might experience discomfort, to ensure that the biopsy or blood tests can accurately assess whether you have celiac disease. Also, it's helpful that you’ve seen improvements in your health on a gluten-free diet. Keep monitoring your symptoms closely during the gluten challenge, and make sure to communicate everything to your gastroenterologist. Ultimately, the goal is to get a clear diagnosis so that you can make the best decisions for your long-term health. Stay strong through the process—you’re doing great in advocating for yourself!

That’s a really interesting idea about IgA deficiency. I’ve had chronic sinus infections for more than 10 years as well. I’ll bring it up next time with my PCM.    in the meantime I’m going to supplement B1 and see if there’s any change. I’m also doing l. reuteri plus a regular multistrain probiotic which seems to be helpful. Do digestive enzymes help at all, or it’s a ymmv situation?