Photo: CC--K-State Research and Extension

What's the relationship between celiac disease and liver histology, serology and treatment response?

Celiac disease is diagnosed on the basis of ESPGHAN criteria, and clinical response to gluten-free diet. Researchers have noted histological abnormalities on liver biopsies in patients with celiac disease, but have rarely described the abnormalities in detail.

A team of researchers recently set out to assess the histological spectrum of 'celiac hepatitis' and to see if a gluten-free diet can reduce such features. 

Traditional scalloped potatoes benefit greatly from a bit of ham and onion. Photo: CC--Lori L. Saltieri

Sometimes when those chilly winds begin to blow, and the temperatures fall, the days get visibly shorter, what we need and what we want is comfort food. Well, look no further than this simple, easy twist on scalloped potatoes. A little ham and a bit of cheese work wonders to turn that old favorite into a meal all its own.

Is Celiac Disease Seriously Under-Diagnosed? Photo: CC--US Army

Are doctors even getting close to diagnosing the actual number of cases of celiac disease? Or are they missing the vast majority?

Researchers have said for some time that there are far more people with celiac disease than are being diagnosed, and that the vast majority of cases go undiagnosed.

If a new study by Canadian nutrition researchers is any indication, most cases of celiac disease remain undiagnosed.

Image: CC--TAKA@P.P.R.S

When I first saw the big advertisement that came through the mail I thought, "Wow, we are really getting somewhere!" However, when I read their advertisement my mind was quickly changed by what seems like false advertising.

It reads like a great deal of boasting, followed by the "disclaimer" (At the bottom. Who reads to the end of an advertisement?)

Here's the disclaimer:

"Domino's pizza made with a Gluten Free Crust is prepared in a common kitchen with the risk of gluten exposure. Therefore, Domino's DOES NOT recommend this pizza for customers with celiac disease. Customers with gluten sensitivities should exercise judgment in consuming this pizza."

Genes acting in concert could worsen celiac disease symptoms. Photo: CC--Glen Bowman

A new study shows that activation of IRF1 and IRF1-regulated genes together, both directly and via the interleukin-18 dependent inflammasome, would greatly increase the severity of the inflammatory response.

Celiac disease is a chronic inflammatory disease of the small intestine mucosa due to permanent intolerance to dietary gluten.

A team of researchers recently set out to clarify the role of small intestinal epithelial cells in the immunopathology of celiac disease, especially the influence of celiac disease-associated bacteria.

Photo: CC--Sergio Santos

Are primary care physicians under-testing for celiac disease in patients with iron deficiency anemia? A new survey of primary care doctors indicates that they are.

It's fairly common for people with celiac disease to develop iron deficiency anemia (IDA), but researchers don't know much about the frequency with which primary care physicians test for celiac disease in patients with IDA.

A team of researchers recently set out to describe how primary care doctors approach testing for celiac disease in asymptomatic patients with IDA.

Photo: CC--Bruce Geunter

What’s the best way to way to measure the gluten content of gluten-free foods, particularly those based on purified wheat starch?

These baked apples are just the way to start your Halloween season. Photo: CC--Healthier Michigan

Filled with nuts and cranberries, these easy to cook baked apples are slow-cooker magic. Top them with sea salt caramel sauce and vanilla ice cream, and you’ve got the makings for a memorable treat. These baked apples are just the way to start your Halloween season.

Can undetectable negative tTG IgA antibodies predict mucosal healing in treated celiac disease patients? Photo: CC--Binary Koala

Tissue transglutaminase (tTG) immunoglobulin A (IgA) testing is a sensitive adjunct to the diagnosis of coeliac disease. The threshold for positivity was developed for diagnosis, with negative results reported as below the reference value (<4 U/mL).

A team of researchers recently set out to investigate if an undetectable tissue transglutaminase IgA antibodies (tTG IgA<1.2 U/mL) is more predictive of healing compared to patients with negative but detectable serology (1.2-3.9 U/mL).

Image: CC--Dennis Jarvis

Despite the economic downturn, the cost of healthy products has not diminished. Sales have continued to grow in this sector thanks to the many information campaigns aimed at raising consumer awareness of the health benefits of consuming gluten free products. Manufacturers have responded to the growing demand by expanding the variety of products they offer. Many consumers, including those that cannot eat gluten, do not want to give up eating products specially designed for them although they cost even more than traditional food. The demand for products that address food intolerance continues to grow.

Photo: CC--See Ming Lee

A Merrill Lynch broker in Denver has sued the firm in federal court, claiming that its systemic "sabotage" of his relationship with clients during and following two medical leaves have cost him hundreds of thousands of dollars.

In a case filed this summer in federal court in Colorado, Kirk Kringel, a broker with Merrill since 2010, alleges that the company violated his rights under the Family Medical Leave Act by retaliating against him for taking the two medical leaves, including one that was related to celiac disease.

Slow cook chicken soup helps you start fall off right. Photo: CC--Jess (Paleo Grubs)

If you're looking for a delicious, easy to make meal that is perfect for the start of fall, this slow-cook chicken vegetable soup is just the thing.

Directions:
Combine onion, celery, garlic, thyme, sage, and 1 tablespoon oil in a large slow cooker.

Cover and cook on high until vegetables have slightly softened, about 10-12 minutes...

Can probiotics delay onset of gluten intolerance in children? Photo: CC--Ryan Schneider

New trial data suggests that the probiotic strains Lactobacillus plantarum Heal 9 and Lactobacillus paracasei 8700:2 may provide support for the immune system and delay the onset of gluten intolerance in children.

The findings, recently presented at the International Celiac Disease Symposium in New Delhi, suggest that Probi's patented probiotic strains have a 'surprisingly consistent' effect on suppressing coeliac autoimmunity and may delay the onset of the disease in children who are genetically pre-disposed to the condition.

Baked sausage and wild rice anchor this memorable dinner dish. Photo: CC--Anokarina

Casserole season is upon us once again. This hearty baked sausage and wild rice is just the thing for a chilly fall night. Baked sausage and wild rice anchor this memorable dinner dish.

Image: CC--bodegón simple

Gluten-free doesn't have to be complicated or confusing. It can be easy and delicious without thinking twice about the processed foods in the food stores. Simply eat Clean. What's Clean, you say? It's about eating real, wholesome, naturally gluten-free foods and steering clear of processed, packaged foods.

Do adolescent celiac patients face a higher risk of cardiovascular disease? Photo: CC--Kai Schreiber

Recent data show that more adults with celiac disease may face a higher risk for cardiovascular disease compared with the general population.

A team of researchers recently set out to investigate the association of with cardiovascular disease risk factors at late adolescence in a cross-sectional population-based study.

Our Ultimate Gluten-Free Candy Listing! Image: CC--jeannette_s

Halloween is once again upon us, and that means candy galore, and plenty of questions about gluten-free candy. Here is Celiac.com's list of Safe Gluten-free Candy for Halloween 2017.

This year, we offer our most up-to-date list of safe, gluten-free Halloween candies, and anther list of candies to watch out for. Below our SAFE, GLUTEN-FREE Halloween candy list, you will find a list of UNSAFE, NON–GLUTEN–FREE candies, along with a partial list of major candy makers, links to their company websites, and other resources.

Grain industry study touts benefits of bread. Photo: CC--Kevin Dooley

As people eat less processed foods, and more people adopt a gluten-free diet, manufacturers are selling less and less refined wheat flour, less bread, rolls, and cereals.

Consumption of wheat is plummeting, and that has the people who grow wheat wondering what to do.

Well, one thing wheat growers can do is hire researchers to study the problem in such a way that the logical conclusion is that foods made from refined grains, such as breads, rolls, and cereals, aren’t really that bad after all.

Photo: CC--NAIAD

For anyone following the efforts by ImmusanT to develop a vaccine for celiac disease, the company's recent presentations at the 2017 International Celiac Disease Symposium (ICDS) in New Delhi, India, were welcome news.

Nexvax2® is a therapeutic vaccine intended to protect against the effects of gluten exposure while maintaining a gluten-free diet in HLA-DQ2.5+ patients with celiac disease.

The company announced at ICDS 2017 that it has presented data showing the immunologic basis for the early clinical effects of gluten in celiac disease.

On November 9th, Beyond Celiac will host the first ever Bold Beyond Research Symposium, bringing together noted researchers, clinicians and community members to explore the current state and future directions of celiac disease research. The Symposium, a free event, will be held on the Drexel University campus in Philadelphia also webcast to a live audience worldwide. The event, sponsored in part by CBS Radio Philadelphia, will spur dialogue about research/community partnerships and drive celiac disease community involvement.