Celiac.com 11/07/2017 - Researchers still don't have much good data on the consequences of antibiotic use in early life and how that relates to the risk of certain autoimmune diseases.
A team of researchers recently set out to test the association between early-life antibiotic use and islet or celiac disease autoimmunity in genetically at-risk children prospectively followed up for type 1 diabetes (T1D) or celiac disease. Their study is part of a larger study called The Environmental Determinants of Diabetes in the Young, or TEDDY, for short.
The reasearch team enrolled HLA-genotyped newborns from Finland, Germany, Sweden, and the United States between November 20, 2004, and July 8, 2010, and analyzed data from November 20, 2004, to August 31, 2014.
They also enrolled individuals...

Celiac.com 03/11/2019 - Many researchers believe that intestinal microbiota play a key role in the development of celiac disease. Since gut microbiota are strongly influenced by systemic antibiotics, especially in early life, the role of antibiotics in the development of celiac disease comes into question. Do antibiotics in infancy influence celiac disease rates later on?
The team’s observational nationwide register-based cohort study included all children born in Denmark from 1995 through 2012, and Norway from 2004 through 2012. They followed the children born in Denmark until May 8, 2015 and the children born in Norway until December 31, 2013. 
In all, they gathered medical data on more than 1.7 million children, including 3,346 with a diagnosis of celiac disease. Any pa...

Celiac.com 06/28/2019 (originally published 07/12/2010) - The report by R.H. Wasserman titled “Vitamin D and the Dual Processes of Intestinal Calcium Absorption“ is very important.  I have some writing to do (and corrections to make) as a result of reading this.  It helps to explain why dogs don’t suffer from clinical osteoporosis.  It’s obvious that there are processes taking place in the ileum of humans that do not take place in the dog.  
This came up as I was counseling an Internet acquaintance concerning his osteoporosis.  He was not improving with conventional therapy and was also suffering from chronic lymphocytic colitis.  I knew that the ileum actively absorbs calcium but the numbers in the study above were news to me.  I’ve been telling people for years that one of the b...

Celiac.com 12/26/2019 - Earlier studies have suggested a relationship between infection, associated antibiotic exposure, and the risk of celiac disease. However, there hasn't been a comprehensive evaluation of those studies that might help to deliver a clear answer.
To address this, a team of researchers recently conducted a meta-analysis to investigate the relationship between infection, associated antibiotic exposure, and celiac disease risk.
They began looking for relevant studies by searching the PubMed, Embase, and Cochrane databases for articles published through April 2019. They used random effects models to determine overall pooled estimates and 95% confidence intervals (CIs). 
Their meta-analysis contained 19 observational studies, including 15 on infection ...