dixonpete
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John Scott reacted to a comment on a blog entry:
Another conversation with ChatGPT about hookworms
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Another conversation with ChatGPT about hookworms
dixonpete commented on dixonpete's blog entry in Pete Dixon
I suppose it's all in how you ask the question. I just asked ChatGPT how much it would cost to resolve my gut issues the way hookworms have, and ChatGPT's response was "$15,000–$30,000/year for the most plausible UC biologic/small-molecule route, or $10,000–$40,000+/year for omalizumab-style allergy modulation". That assumes such medication actually wor... -
John Scott reacted to a blog entry:
Another conversation with ChatGPT about hookworms
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<ME> i have extreme reactivity to gluten and ulcerative colitis, or at least I do when not on hookworms. this is accompanied by broad food sensitivities. when using hookworms I am essentially normal, no symptoms doesn't this simply point to the idea my gut immune system is ok, but an expected link in the chain has to be there, and that link is hookworms ...
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Name reacted to a blog entry:
Hookworms and ChatGPT5
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Name reacted to a comment on a blog entry:
Hookworms and ChatGPT5
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@dixonpete, I've seen a number of your posts about hookworms and celiac. I am fascinated (and, tbh, a little disgusted). I ask myself the question, What evidence would be sufficient to convince me to try this. Frankly, I don't know.
My reason for posting, though, is to ask you personal medical questions that I hope you are comfortable answering.
- how were you diagnosed with celiac in the first place? what were your IgA and biopsy scores, if any?
- have you been getting standard celiac medical followup, and if so, what are the scores?
It sounds like the therapy permits you to eat gluten without the acute symptoms of celiac. Did you / do you have any of the non-alimentary symptoms, such as vitamin or other nutrient deficiencies, hypothyroidism, brain fog, etc. If so, how do these track during your therapy cycle?
Based...
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As for doubling the frequency of inoculations, that would mean doubling the frequency of incubations. Twice the work for no gain?
I know 25 larvae might seem high, but I don't experience side effects, and I know since they die off at six months or so (with me) that I'm not building up a large colony. So I think I'm good.
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Just to clarify my question: you currently inoculate every 6 mo +/- when the hookworms die and the therapy wears off. --and you become vulnerable to gluten. If you took half the dose +/- every 3 mo, couldn't you get a more even therapy?
I get it that it's work to run the incubation and innoculation. It's more of a curiosity question on my part.
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I inoculate every 5.5 months, and it appears that with me the hookworms die off around 6.5 months. The larvae don't develop into their adult form for 30 days or so, so you can't count on any immune help till then.
It's true doing it your way there would less chance of running out. I know a guy who does 2 larvae every 6 weeks. I suppose my model is the laziest possible, with the minimum number of inoculations. It is pretty cool not to have worry about it except for 2x a year.
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There is a difficulty getting hookworm larvae into the US
dixonpete posted a blog entry in Pete Dixon
With Donald Trump’s removal of the de minimis exemption for packages entering the United States, there has been increased scrutiny of inbound shipments, including those from helminthic therapy providers. The practical effect appears to be a near stoppage of Necator americanus larvae entering the U.S. I’ve previously written about incubation and self-sup... -
John Scott reacted to a blog entry:
Inoculation day!
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I did the hookworm larva collection and inoculation today. It took 1/2 hr with doing everything right and safely, including clean-up. You can see the 5 jars I prepared a week ago in the pic. Only #2 jar had a good number of larvae so it was the only jar I used. I placed enough drops onto a checker board scored Petri dish until I had 25 and soaked them...
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Oldturdle reacted to a comment on a blog entry:
Hookworms and ChatGPT5
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Colleen H reacted to a comment on a blog entry:
Hookwormed status report
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On September 23, 2025, I did my latest inoculation. It was right around the five-month mark — plenty of time to avoid the expected adult hookworm die-off in my gut at around 6 to 6.5 months. I never noticed any interruption of “worm services.” Neither my gluten reactions nor the colitis ever reared their ugly heads, so it appears I had a smooth transition with ...
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John Scott reacted to a comment on a blog entry:
Hookworms and ChatGPT5
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John Scott reacted to a blog entry:
Hookworms and ChatGPT5
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I asked a logical follow-up question to ChatGTP5: Can you estimate what percentage of celiac hookworm hosts like myself achieve full remission from the disease? ChatGPT said: Great question, Pete. Let’s be very clear here: There isn’t a single hard number published for “what percentage of celiacs with hookworms achieve full remission,” but...
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I recently sprang for a ChatGPT5 subscription just to play with it and have found it to be a revelation. ChatGPT5 has become my new best friend helping me to explore and answer questions that have been nagging me sometimes for years. Of course our conversation turned to hookworms and celiac disease as well as my other condition, ulcerative colitis. ChatGPT...
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Scott Adams reacted to a comment on a blog entry:
Hookwormed status report
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I should add that hookworms aren't a cure for celiac disease. Some people, and I couldn't tell you how many, stop evincing the symptoms of celiac disease while their hookworm colonies are healthy. Others have a reduction in the severity of their reactions to gluten, but should still stay well away from it. And other people don't seem to be helped much at...
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I was lucky (!) in that I would very quickly get sick after ingestion with something contaminated with gluten so it was easy to figure out the offender. I also had a very restricted diet and only ever introduced one new food item per day for this very reason. One memory that sticks out was pistachios. They put flour in the bag to stop the nuts sticking...
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Took about 20 minutes and 1/2 of that was clean-up. As per what has become my usual process, I prepared five small jars with the expectation of only using the one jar with the greatest population of larvae. Today is August 29th, so given that a week appears to be sufficient time for the eggs to hatch and the larvae to do their thing of migrating down to the...
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Probably the best Helminthic Therapy video I've seen
dixonpete commented on dixonpete's blog entry in Pete Dixon
I definitely fall into the category of being a celiac who hated being celiac and very much wanted that beer and sandwich. In fact, I just had a couple of regular bread ham sandwiches. Sadly no beer though. Trying to cut down. I can relate though to those celiacs who said that they would never touch gluten again, hookworms or no. Those memories of past... -
Probably the best Helminthic Therapy video I've seen
dixonpete commented on dixonpete's blog entry in Pete Dixon
There is a discussion of celiac disease at 42:56. -
A couple of therapists who use hookworms in their practice and a Crohn's patient talk about their use of hookworms and other helminths. Hookworm treatment is the same for celiacs as it is for Crohn's or any other Inflammatory Bowel Disease condition.
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Not much going on to report. My last inoculation of 25 Necator americanus hookworm larvae occurred April 11 2025, and I'm due to start incubating Aug 27 2026 and inoculate again with 25 larvae Sep 3 2025. Over the years I've seen my celiac/ulcerative colitis symptoms return six month-ish after inoculation, so I've settled on a frequency of a little less than...