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Need Help With Test Results Please?


caymanislands

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caymanislands Newbie

My Gliadin tests all came back normal but my IgG to Gluten came back high. What does this mean? Not celiac but gluten intolerance?? My biggest problems are constipation, dry itchy skin, bloated stomach by the end of the day and just unwell feeling overall usually. I am only 35 but tired all the time. Also tested with iron deficiency anemia which the doctor thinks could be related to a gluten intolerance in that I am not absorbing nutrients well. Can I have some help with this?

Thanks!

Shelly


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nora-n Rookie

Which tests did you have?

Usually they test the ttg, tissue transglutaminase.

Was it the antigliadin IgG that was elevated?

The celiac tests are:

EMA endomyeium antibody test, very specific

Ttg IgA very specific

Ttg IgG they do this if total IgA is low

antigliadin IgA less sepcific, an older test

antigliadin IgG "

they do the IgG version if the total IgA is low

caymanislands Newbie

Thanks. The tests that were done are:

Gluten IgG = high

Gliadin IgG = normal, it was only 2

Gliadin IgA = normal, it was 7

Gliadin IgA = <5.0 reference is 0.0 - 4.9

I think they did 2 tests to be sure.

Gliadin was <10.0 reference is 0.0 - 9.9

Reticulin was <1:10

Autoantibodies

Endomysial IgA AB <1:10

So it was just the Gluten IgG that was high which to me is just a food intolerance, correct? This is what my doctor is telling me and saying this is likely the cause of my anemia and constipation. Does this sound right to you?

Thanks.

Shelly

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    • trents
      Yes, it does. And joint pain is another celiac symptom that is now well-recognized. 
    • ThomasA55
      Does my iron loss sound like celiac to you?
    • trents
      Being as how you are largely asymptomatic, I would certainly advise undertaking a gluten challenge in order to get formal testing for celiac disease. We have many forum participants who become violently ill when they undertake a gluten challenge and they therefore can't carry through with it. That doesn't seem to be the case with you. The reason I think it is important for you to get tested is that many or most people who don't have a formal diagnosis find it difficult to be consistent with the gluten-free diet. They find ways to rationalize that their symptoms are due to something other than celiac disease . . . especially when it becomes socially limiting.  The other factor here is by being inconsistent with the gluten free diet, assuming you do have celiac disease, you are likely causing slow, incremental damage to your gut, even though you are largely asymptomatic. It can take years for that damage to get to the point where it results in spinoff health problems. Concerning genetic testing, it can't be used for diagnosis, at least not definitively. Somewhere between 30 and 40% of the general population will have one or both of the two genes known to be associated with the development of active celiac disease. Yet, only about 1% of the general population will develop active celiac disease. But the genetic testing can be used as a rule out for celiac disease if you don't have either gene. But even so, that doesn't eliminate the possibility of having NCGS (Non Celiac Gluten Sensitivity).
    • ThomasA55
    • trents
      Welcome to the celiac.com community, @ThomasA55! Before I give my opinion on your question about whether or not you should undergo a gluten challenge, I would like to know how you react when you get a good dose of gluten? Are you largely asymptomatic or do you experience significant illness such as nausea and diarrhea? You mentioned intermittent joint pain before you began experimenting with a low gluten diet. Anything else?
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