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Saliva Test Positive--Anyone Else Like Me?


gobruins2

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gobruins2 Newbie

So I have suffered the last year and half with too many symptoms to list (extreme joint pain, carpal tunnel, hypertension, flu like feeling, intolerance to heat, inability to exercise (makes hands/arms/legs go numb at night), IBS, fluid excretion from breast etc.) and have been diagnosed with a form of auto immune arthritis (Ankylosing Spondylitis) and fibromyalgia. All of my test results run for celiac have come back negative (DQ2 and DQ8). However, a new rheumatologist I just saw did a Saliva Gliadin Ab, SIgA test that came back with a high positive at 63 (15 is considered positive). My new Dr. said I must be gluten free for the rest of my life and he is hopeful that this will help with many of my symptoms. I am also borderline anemic, have overgrowth of yeast, and low functioning pancreas, all of which he says is consistent with gluten intolerance. When I pressed him on the difference between celiac and my results, he said since my test result was so high that in his opinion me being positive for celiac "was just a matter of time" if I continued to eat gluten. He was very adamant about my situation and said the proof is in the elimination of the gluten and how I feel 3-6 months later. . ..

I am so hopeful this will help, but I am wondering if there are any others out there that have been given this type of saliva test? I guess I am remain a little skeptical since my blood markers all were negative for celiac. I will say I have been gluten free for 18 days and my "IBS" is much, much better. I still have lots of other aches, pains etc. but I remain hopeful that over time these too will diminish.

Thanks for your feedback on this saliva test and your journeys.


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    • trents
      Yes, it does. And joint pain is another celiac symptom that is now well-recognized. 
    • ThomasA55
      Does my iron loss sound like celiac to you?
    • trents
      Being as how you are largely asymptomatic, I would certainly advise undertaking a gluten challenge in order to get formal testing for celiac disease. We have many forum participants who become violently ill when they undertake a gluten challenge and they therefore can't carry through with it. That doesn't seem to be the case with you. The reason I think it is important for you to get tested is that many or most people who don't have a formal diagnosis find it difficult to be consistent with the gluten-free diet. They find ways to rationalize that their symptoms are due to something other than celiac disease . . . especially when it becomes socially limiting.  The other factor here is by being inconsistent with the gluten free diet, assuming you do have celiac disease, you are likely causing slow, incremental damage to your gut, even though you are largely asymptomatic. It can take years for that damage to get to the point where it results in spinoff health problems. Concerning genetic testing, it can't be used for diagnosis, at least not definitively. Somewhere between 30 and 40% of the general population will have one or both of the two genes known to be associated with the development of active celiac disease. Yet, only about 1% of the general population will develop active celiac disease. But the genetic testing can be used as a rule out for celiac disease if you don't have either gene. But even so, that doesn't eliminate the possibility of having NCGS (Non Celiac Gluten Sensitivity).
    • ThomasA55
    • trents
      Welcome to the celiac.com community, @ThomasA55! Before I give my opinion on your question about whether or not you should undergo a gluten challenge, I would like to know how you react when you get a good dose of gluten? Are you largely asymptomatic or do you experience significant illness such as nausea and diarrhea? You mentioned intermittent joint pain before you began experimenting with a low gluten diet. Anything else?
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