No popular authors found.
Ads by Google:

Categories

No categories found.


Get Celiac.com's E-Newsletter





Ads by Google:


Follow / Share


  FOLLOW US:
Twitter Facebook Google Plus Pinterest RSS Podcast Email  Get Email Alerts
SHARE:

Popular Articles

No popular articles found.
Celiac.com Sponsors:

Rates of Refractory Celiac Disease Down Sharply in Last 25 Years


Photo: CC--Mark Morgan

Celiac.com 01/30/2017 - A team of researchers recently set out to analyze potential changes in occurrence of complicated coeliac disease over the last 25 years.

The research team included W. Eigner, K. Bashir, C. Primas, L. Kazemi-Shirazi, F. Wrba, M. Trauner, and H. Vogelsang. They are variously affiliated with the Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University Hospital of Vienna, Vienna, Austria, and with the Department of Pathology at the Medical University of Vienna in Vienna, Austria.

The team included and evaluated a total of 1,138 patients based on time of first presentation at the Medical University of Vienna, Austria.

They assessed occurrences of refractory celiac disease and associated malignancies in 5-year intervals from January 1990 until December 2014, and then compared results over time. Twenty-nine patients, or 2.6%, were diagnosed with refractory celiac disease. Of these, 65.6% were females averaging 62.8 years of age at diagnosis.

Ads by Google:

The proportion of those patients was 2.6%, 3.1%, 3.3%, 2.7% and 0.5% for the 5 year intervals from 1990 through 2014. The number of refractory cases has been generally decreasing since 2000 (P = 0.024). During that time, a total of seven patients presented with lymphoma, totaling 0.6%, 0.4%, 1.1%, 0.8% and 0% of patients each year, respectively.

Similarly the number of patients with adenocarcinoma, four patients total, decreased to 0% until 2014. Nearly 50% of patients suffering from refractory disease died during the study period. Meanwhile, 71.4% all patients diagnosed with lymphoma died, with a 5-year survival rate of 28.6%.

Over the past 15 years, rates of complicated celiac disease have been decreasing. This may be due to increased celiac disease awareness, along with optimized diagnosis and treatment with avoidance of long-term immunological disease activity.

Known risk factors for refractory celiac disease and related cancer include untreated symptomatic disease and delayed diagnosis.

Source:

Celiac.com welcomes your comments below (registration is NOT required).












Related Articles



Comments




Rate this article and leave a comment:
Rating: * Poor Excellent
Your Name *: Email (private) *:




In Celiac.com's Forum Now:


Sorry your not responding well I've been gluten free dairy free and soy free since january. I didnt notice ANY improvements until that lucky 6 montb Mark you hear about quite often. There is definitely truth to that time period. With that being said I too had alot of dizziness heart Palps panic a...

Yes, I have heard about mushrooms and possible gluten exposure is in the medium they are grown on that can be concerning. Plus, you are not supposed to really wash mushrooms, just brush them off per chefs. http://www.foodnetwork.com/how-to/articles/how-to-clean-and-store-mushrooms-a-step-...

Welcome! The best way to determine if you have celiac disease is to take a simple blood test, but you need to be consuming gluten daily. So, do not go gluten free before testing. http://www.cureceliacdisease.org/screening/ honestly, those allergy tests are not accurate. h...

He is a kid. Gluten may be still getting into his diet. That is why testing is critical. Now, more than ever, since he is a teen. I read in one celiac book, Gluten Freedom by Dr. Fasano, that one teen patient was getting sick. His parents were perplexed. Speaking to the doctor alone, th...

Good luck ill say a prayer. I try to zone out breath in and out slow. Ive had many procedures. Ice pack on wrist slows circulation. Think of flowers or the wind close your eyes and relax. Practice at home.