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Genetic Markers for Celiac Testing
In 1994 I was diagnosed with celiac disease, which led me to create Celiac.com in 1995. I created this site for a single purpose: To help as many people as possible with celiac disease get diagnosed so they can begin to live happy, healthy gluten-free lives. Celiac.com was the first site on the Internet dedicated solely to celiac disease. In 1998 I foundedÂ The Gluten-Free Mall, Your Special Diet Superstore!, and I am the co-author of the book Cereal Killers, and founder and publisher of Journal of Gluten Sensitivity.View all articles by Scott Adams
By Vijay Kumar, PhD., IMMCO Diagnostics, Inc. - IMMTEST@AOL.COM
The genetic markers associated with celiac disease are:
- HLA DQalpha *0501
More than 90% of patients with celiac disease have these markers. Negative tests for these markers in conjunction with negative serum antibody tests suggest an absence of celiac disease. However, positive tests for the genetic markers do not necessarily mean that the patient has celiac disease. In conclusion, genetic markers can be used as a test to exclude celiac disease as a diagnosis.
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Duodenal Biopsy Works Well for Diagnosis and Follow-up of Celiac Disease
A trio of researchers recently compared duodenal and jejunal small intestinal biopsies for diagnosis and follow-up of celiac disease.... [READ MORE]
Celiac Disease Genetic Testing Awareness Campaign Launched by Kimball Genetics
If you would like to learn more about celiac disease
genetic testing, or read about my personal experience with Kimball Genetics,
be sure to read the following two related articles:
Your DNA Results Indicate:
Super Celiac! By Scott Adams
Understanding the Genetics
of Gluten Sensitivity by Dr.... [READ MORE]
Future Enzyme Treatment Possible for People with Celiac Disease
J Pharmacol Exp Ther.... [READ MORE]
The following is excerpted from an article that was published in the American Celiac Society newsletter by Joseph A. Murray, MD of the Mayo Clinic Rochester, MN, who is a gastroenterologist who specializes in treating Celiac disease
for whom there is a high suspicion for celiac disease should have
a small bowel biopsy which can be obtained by an experienced endoscopist
in the distal duodendum.... [READ MORE]