Skin Biopsy Results?

[MacieMay]

These are my 18 mos olds skin biopsy results... Any insight will be greatly appreciated!

R, arm punch: Vacuolar interface dermatitis with perivascular and periadnexal lymphocytic inflammation

Comment: The histologic findings are consistent with a connective tissue disease

I don't understand why there is nothing about antibodies here?!?! If her rash is not related to gluten and is a being cause by a different autoimmune disease, shouldn't another type of antibody be here?

My husband took her for the biopsy. I do not know if the Derm biopsied the skin next to the lesion or lesion itself. My husband literally had beg him to do the biopsy, again we were being brushed off with a dx of eczema. It was a 0.2cm X 0.2cm x 0.2cm punch biopsy. If that helps anyone.

Please, anyone who has had negative skin biopsies for DH or any other experience with a skin biopsy, please share your insight. These results seems so vague to me. I feel like calling the lab to ask them questions.

Thanks!

MadsMegsandMacies Mom

[ravenwoodglass]

If the biopsy was done next to a lesion you should be able to see where it was done. Did your husband watch the procedure? If he did can he tell you about where the biopsy was done? Can you call the doctors office and ask? The placement of the biopsy and whether it was on the lesion itself should be in the record.

I would ask to follow this up with the doctor. Excema is not a connective tissue disorder as far as I know. You could also seek out a second opinion with another derm if you don't think the biopsy was done correctly.

[nora-n]

For DH, they have to look for DH in a special way.

I doubt they look for DH unless prompted.

They have to look at the sample in an electronic microcope I think, and look for fluorescent IgA deposits somehow,

if they took the sample somewhere where there has been a lesion, the IgA is used up and they cannot diagnose DH.