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  • Scott Adams

    Atopic Dermatitis More Common in Adults with Multiple Autoimmune Diseases

    Scott Adams
    Reviewed and edited by a celiac disease expert.

      Adults with multiple autoimmune diseases were more likely to develop atopic dermatitis those with just one autoimmune disease.

    Terrestrial connections. Image: CC BY-ND 2.0--Masha Sardari
    Caption: Terrestrial connections. Image: CC BY-ND 2.0--Masha Sardari

    Celiac.com 01/04/2021 - Researchers have long known that the common chronic skin disorder atopic dermatitis is associated with other atopic conditions. A growing body of evidence supports a connection with non-atopic conditions, including autoimmune diseases, such as celiac disease, but data are limited with respect to autoimmune conditions. To remedy the situation, a research team recently examined the connection between atopic dermatitis and autoimmune diseases.

    The research team included L.U. Ivert, C.F. Wahlgren, B. Lindelöf, H. Dal, M. Bradley, and E.K. Johansson. They are variously affiliated with the Dermatology and Venereology Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden; the unit of Dermatology, Theme Inflammation and Infection, Karolinska University Hospital, Stockholm, Sweden; the Theme Cancer unit, Karolinska University Hospital, Stockholm, Sweden; and the Dermatological and Venereal Clinic, Södersjukhuset, Stockholm, Sweden.

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    For their case–controlled study, the team looked at the Swedish national healthcare registers, and looked at data from the entire Swedish population, aged 15 years or younger, from 1968 to 2016. 

    The researchers matched all atopic dermatitis cases by sex and age to healthy controls; including cases with an inpatient diagnosis of atopic dermatitis from 1968, and/or a specialist outpatient diagnosis of atopic dermatitis from 2001. In all, the team found 104,832 cases of atopic dermatitis, and matched them to 1,022,435 control subjects.

    Adults with multiple autoimmune diseases were more likely to develop atopic dermatitis than those with just one autoimmune disease. The associations were especially strong between atopic dermatitis and autoimmune dermatological, gastrointestinal and rheumatological diseases. 

    The study was funded by the Swedish Asthma and Allergy Association Research Foundation, Hudfonden (The Welander‐Finsen Foundation), and The Swedish Society for Dermatology and Venereology. The authors declare no conflicts of interest.

    These results invite further study of the relationship between atopic dermatitis and autoimmune conditions, such as celiac disease.

    Read more in the British Journal of Dermatology

    Edited by Scott Adams


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  • About Me

    Scott Adams was diagnosed with celiac disease in 1994, and, due to the nearly total lack of information available at that time, was forced to become an expert on the disease in order to recover. In 1995 he launched the site that later became Celiac.com to help as many people as possible with celiac disease get diagnosed so they can begin to live happy, healthy gluten-free lives.  He is co-author of the book Cereal Killers, and founder and publisher of the (formerly paper) newsletter Journal of Gluten Sensitivity. In 1998 he founded The Gluten-Free Mall which he sold in 2014. Celiac.com does not sell any products, and is 100% advertiser supported.

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