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  • Jefferson Adams
    Jefferson Adams

    Researchers Look to Nail Down Effects of COVID-19 on US Celiac Patients

    Reviewed and edited by a celiac disease expert.

    Some researchers are looking at celiac disease patients with special interest in regards to clinical outcomes after a diagnosis of COVID-19. 

    Researchers Look to Nail Down Effects of COVID-19 on US Celiac Patients - Image: CC PDM 1.0--NavyMedicine
    Caption: Image: CC PDM 1.0--NavyMedicine

    Celiac.com 12/27/2021 - To better understand the rates of hospitalization, mortality, thrombosis or intensive care unit (ICU) treatment in individuals with celiac disease and COVID-19, a team of researchers recently set out to assess the clinical characteristics, hospitalization and mortality rates of COVID-19 among U.S. celiac disease patients.

    The research team included Emad Mansoor, Muhammed Mustafa Alikhan, Jaime Abraham Perez, Kayla Schlick, Mohannad Abou Saleh, and Dr Alberto Rubio-Tapia. They are variously affiliated with the Department of Medicine; Digestive Health Institute, University Hospitals of Cleveland, Cleveland, Ohio, USA; the Department of Medicine, University Hospitals of Cleveland, Cleveland, Ohio, USA; the Center for Clinical Research, Case Western Reserve University, Cleveland, Ohio, USA, Department of Medicine; the Division of Gastroenterology, Hepatology, and Nutrition, Cleveland Clinic, Cleveland, Ohio, USA.

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    The team notes that their work was sparked, in part, by Belli et al1 regarding outcomes of COVID-19 in liver transplant candidates. The authors in Belli et al concluded that liver transplant candidates were at risk of early death, especially those with decompensated cirrhosis and model for end-stage liver disease score of 15 or above.

    That research team reviewed clinical outcomes in celiac patients after a diagnosis of COVID-19.  Although the evidence of COVID-19's impact of other chronic disorders is emerging, researchers still don't know very much about the consequences of COVID-19 infection in people with celiac disease. 

    To compile the celiac disease cohort, the team used the TriNetX healthcare research network to compile the electronic medical records of adults with celiac disease, and confirmed COVID-19 infection, from 51 healthcare organizations in the USA, between 1 January 2020 and 7 July 2021. 

    For the non-celiac disease cohort, they also identified COVID-19 positive patients, with no history of celiac disease, from the same time period. They defined celiac disease by the International Classification of Disease, 10th Revision (celiac disease-10) diagnostic code and related codes, such as villous atrophy present on biopsy of small intestine and positive autoantibody screening. 

    For both groups, the team studied the risk of hospitalization, mortality, thrombosis, and ICU requirement within 90 days of COVID-19 diagnosis. They also performed 1:1 propensity score matching using a greedy nearest-neighbor matching algorithm to account for potential confounding variables.

    Overall, the researchers found no significant differences among any of the measured outcomes in those with celiac disease, compared with non-celiac patients with COVID-19, after propensity score matching.

    Understanding more about COVID-19 outcomes of patients with celiac disease will researchers and patients to get a better idea of any potential concerns or options, and potentially lead to better outcomes.

    Read the full findings in Gut

    Reference:

    • Belli LS, Duvoux C, Cortesi PA, et al. COVID-19 in liver transplant candidates: pretransplant and post-transplant outcomes - an ELITA/ELTR multicentre cohort study. Gut 2021;70:10.1136/gutjnl-2021-324879:1914–24. doi:10.1136/gutjnl-2021-324879


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    AnonyousCda

    This Celiac catched Covid19 February of 2020.  

    My celiac symptoms went cold for about 10 Months.  Then symptoms came back with a bit of extreme.  But not as constant.  Still way lesser brain fog.  Being able to think and have energy to get regular goals done day to day.  

    Still say getting Covid19 was the best thing to happen to me in 2020.  But having a foot injury in 2021 have been long in recovery. 

    Covid19 patients tend to have physical injuries down the road especially with feet.  Just look at all the people wearing BOOTS or limping around. 

    Stay strong celiac.  Vitamin A to keep the phlegm from building up in the throat.  Vitamin D, Iodine.  Also pomegranates fruit can help in getting the phlegm to cough out.  Healthy is a priority. 

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    Elizabeth Butler

    I agree. I got fired in 2020 for wearing a mask!! 😂 at a healthcare operation: read “business of healthcare”🙄 I also truly believe I have at the minimum gluten sensitivity becuase i have grass, corn and wheat allergy(tested) and a particular type of skin breakout that no dermatologist for years could correct. I believe it was dermatitis herpetiformis. Ive been gluten free for years at this point and my skin improved immediately. Going vegan later and drinking lemon water has also improved skin and nails. My energy levels are way up and I feel better now than I did at 20. I’m also never sick. I’m 38. Had covid confirmed( had to fake symptoms at same facility I was fired from in 2020 holiday just so I didn’t kill my relatives). Didn’t have anything but loss of smell, and some mild lung diminished capacity( noticed that in subsequent months). Hard to tell if that was because I quit exercising at my prior levels( intense)for 7 months after being let go or from covid…but given what I know about viruses, allergies, and asthma( also diagnosed) and exercise capacities for myself for years I’m guessing covid. The healthcare “industry” has disgusted me at this point. All the way around from covid to its business models to its costs( and insurance don’t even get me started they tell docs how to treat based on what’s covered and what the doc can get paid for so I may as well just ask the insurance what my life’s worth). I wouldn’t go see a doctor if my life depended on it I’d rather leave it to Mother Nature. I’m spent mentally with the whole system. I got my covid vaccine just so I could work.. but I choose J&J. Anything the body can’t destory( according to CDC it can’t be destroyed at least it was on their website vaccine info) should be considered a biological implant( just like a pig/cow/mechanical heart valve) nobody mandates a heart valve even though a needed heart valve is a serious piece of equipment necessary for life. 🧐 strange times we are living in..strange indeed. 

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  • About Me

    Jefferson Adams

    Jefferson Adams is Celiac.com's senior writer and Digital Content Director. He earned his B.A. and M.F.A. at Arizona State University. His articles, essays, poems, stories and book reviews have appeared in numerous magazines, journals, and websites, including North American Project, Antioch Review, Caliban, Mississippi Review, Slate, and more. He is the author of more than 2,500 articles on celiac disease. His university coursework includes studies in science, scientific methodology, biology, anatomy, physiology, medicine, logic, and advanced research. He previously devised health and medical content for Colgate, Dove, Pfizer, Sharecare, Walgreens, and more. Jefferson has spoken about celiac disease to the media, including an appearance on the KQED radio show Forum, and is the editor of numerous books, including "Cereal Killers" by Scott Adams and Ron Hoggan, Ed.D.

    >VIEW ALL ARTICLES BY JEFFERSON ADAMS

     


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