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Flattened Villi

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OK, I've been doing some reading and I'm confused. I've come across the idea that flattened villi doesn't necessarily mean that that person has celiac. But what else would it be?

What sparked my curiosity was this post by tired47. It states:

"Hi! I had the camera pill test done. My results were flattened villa and erosions of small bowel. I had blood work, and biospy which were all negative. Dr. has said he does not think it is celiac/crohn's. I am following the gluten free diet as advised. My family Dr. said it would help "heal" my small bowel. And I am still having severe malabsorption issues... we know it comes from small bowel abnormalities, but why do it have them??? Ideas anyone??? ( I was on mega doses of antibiiotics for H pylori last year)."

I don't understand how can your villi be flattened and yet your doctor would say it's not celiac. What else would it be?

gluten-free since 9/30/09

positive gene test 8/11/09

endoscopy 9/30/09 (awaiting results)

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Celiac.com Sponsor (A8):

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Celiac is the main cause for villi damage, but there are other causes. Some of the other possibilities rarely cause flatened villi, and are usually found in conjunction with Celiac Disease or immuno-deficiencies.

Villi damage can be caused by:

Coeliac Disease

Cows Milk Protein Intolerance

Soy Protein Intolerance

refractory Sprue

Collagenous Sprue

Immunodefiency Synodromes

Mediterranean lymphoma

intestinal ulceration


Intractable Diarrhoea of Infancy

Protein Calorie Malnutrition


Tropical Sprue

Parasitic Disease:




Intestinal Capillariasis

Hookworm Disease

Eosinophilic Gastroenteritis

Contaminated bowel Syndrome

Drug and Radiation Damage

Source: https://www.celiac.com/articles/50/1/Main-C...illi/Page1.html

Hope this helps.


Dx 8/05 via bloodwork and biopsy (total villous atrophy)

13-year old son Dx 11/05 via bloodwork and biopsy

Daughters (16 and 5) have tested negative via bloodwork

A woman is like a tea bag - you never know how strong she is until she gets in hot water. - Eleanor Roosevelt

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